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Showing 1 to 12 of 12 entries
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Genomes, proteomes, and the central dogma.

Circulation. Cardiovascular genetics

Franklin S, Vondriska TM.
PMID: 22010165
Circ Cardiovasc Genet. 2011 Oct;4(5):576. doi: 10.1161/CIRCGENETICS.110.957795.

Systems biology, with its associated technologies of proteomics, genomics, and metabolomics, is driving the evolution of our understanding of cardiovascular physiology. Rather than studying individual molecules or even single reactions, a systems approach allows integration of orthogonal data sets...

An update on biomarkers of heart failure in hypertensive patients.

Journal of hypertension

Gluba A, Bielecka-Dabrowa A, Bielecka A, Mikhailidis DP, Wong ND, Franklin SS, Rysz J, Banach M.
PMID: 22828089
J Hypertens. 2012 Sep;30(9):1681-9. doi: 10.1097/HJH.0b013e3283569a9c.

Biomarkers should have high sensitivity, specificity, reproducibility, be cost-effective, and provide incremental predictive or diagnostic utility over standard risk factors or tests. Despite numerous studies investigating biomarkers in heart failure (HF), there are only a few that predict HF...

The medical treatment of congestive heart failure.

Boletin de la Asociacion Medica de Puerto Rico

Hernández López E.
PMID: 2486900
Bol Asoc Med P R. 1989 Jan;81(1):2-14.

The data herein presented provides persuasive evidence that in addition to diuretics, and probably digitalis (since all studies have included subjects taking this drug) patients with congestive heart failure should also be placed on a vasodilator regimen to slow...

Molecular events in cardiac failure.

The American journal of medicine

OLSON RE.
PMID: 13282934
Am J Med. 1956 Feb;20(2):159-62. doi: 10.1016/0002-9343(56)90184-x.

No abstract available.

Protein trafficking in cardiovascular disease: How the science has evolved and where it must go.

Trends in cardiovascular medicine

Saffitz JE.
PMID: 25666491
Trends Cardiovasc Med. 2015 Jul;25(5):390-1. doi: 10.1016/j.tcm.2015.01.002. Epub 2015 Jan 12.

No abstract available.

[Symposium: physiopathology of congestive heart failure].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

Hayase M, Miyahara M, Kusukawa R, Kinoshita M, Saimyoji H.
PMID: 4677150
Nihon Naika Gakkai Zasshi. 1972 Dec 31;61(13):15-9.

No abstract available.

[Some aspects of metabolic remodeling of myocard during chronic heart failure].

Georgian medical news

Mamamtavrishvili N, Sanikidze T, Pavliashvili N, Kvirkvelia A, Narsia E.
PMID: 18323590
Georgian Med News. 2008 Jan;(154):33-6.

Review provides different mechanisms of "metabolic remodeling" of myocard during Chronic Heart Failure (CHF) including disorder of myocardial energy metabolism, changed activity of intracellular regulatory enzymes, metabolic activity of myocardial interstitium, different metabolic pathways leading to apoptosis of cardiomyocytes....

A review of congestive heart failure.

The Journal of the Singapore Paediatric Society

Wong ML.
PMID: 1305657
J Singapore Paediatr Soc. 1992;34(3):171-9.

No abstract available.

Cardiac metabolism in myocardial failure.

Bibliotheca cardiologica

BING RJ.
PMID: 13800773
Bibl Cardiol. 1959;9:148-55. doi: 10.1159/000383830.

No abstract available.

Sodium-Glucose Cotransporter-2 Inhibitors, Reverse J-Curve Pattern, and Mortality in Heart Failure.

Heart failure clinics

Imprialos K, Stavropoulos K, Papademetriou V.
PMID: 31472887
Heart Fail Clin. 2019 Oct;15(4):519-530. doi: 10.1016/j.hfc.2019.06.004. Epub 2019 Aug 07.

The prevalence of diabetes mellitus and heart failure is increasing. The novel sodium-glucose cotransporters 2 inhibitors offer multidimensional ameliorating effects on cardiovascular and heart failure risk factors. Several studies have assessed the impact on cardiovascular events, with data suggesting...

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention.

Trends in cardiovascular medicine

Xiao S, Shaw RM.
PMID: 25649302
Trends Cardiovasc Med. 2015 Jul;25(5):379-89. doi: 10.1016/j.tcm.2014.12.012. Epub 2014 Dec 29.

Cardiomyocytes, the individual contractile units of heart muscle, are long-lived and robust. Given the longevity of these cells, it can be easy to overlook their dynamic intracellular environment that contain rapid protein movements and frequent protein turnover. Critical gene...

Impact of oral soluble guanylate cyclase stimulators in heart failure: A systematic review and Meta-analysis of randomized controlled trials.

American heart journal

Moghaddam N, Malhi N, Toma M.
PMID: 34283990
Am Heart J. 2021 Nov;241:74-82. doi: 10.1016/j.ahj.2021.07.003. Epub 2021 Jul 18.

BACKGROUND: Soluble guanylate cyclase (sGC) stimulators are a novel class of medications with emerging role in heart failure (HF). The aim of this study is to evaluate the efficacy and safety of oral sGC stimulators in patients with HF...

Showing 1 to 12 of 12 entries