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Intelligent Characterization of Lentil Genetic Resources: Evolutionary History, Genetic Diversity of Germplasm, and the Need for Well-Represented Collections.

Current protocols

Guerra-García A, Gioia T, von Wettberg E, Logozzo G, Papa R, Bitocchi E, Bett KE.
PMID: 34004055
Curr Protoc. 2021 May;1(5):e134. doi: 10.1002/cpz1.134.

The genetic and phenotypic characterization of crops allows us to elucidate their evolutionary and domestication history, the genetic basis of important traits, and the use of variation present in landraces and wild relatives to enhance resilience. In this context,...

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Guerra-García A, Gioia T, von Wettberg E, et al. Intelligent Characterization of Lentil Genetic Resources: Evolutionary History, Genetic Diversity of Germplasm, and the Need for Well-Represented Collections. Curr Protoc. 2021;1(5):e134doi: 10.1002/cpz1.134.
Guerra-García, A., Gioia, T., von Wettberg, E., Logozzo, G., Papa, R., Bitocchi, E., & Bett, K. E. (2021). Intelligent Characterization of Lentil Genetic Resources: Evolutionary History, Genetic Diversity of Germplasm, and the Need for Well-Represented Collections. Current protocols, 1(5), e134. https://doi.org/10.1002/cpz1.134
Guerra-García, Azalea, et al. "Intelligent Characterization of Lentil Genetic Resources: Evolutionary History, Genetic Diversity of Germplasm, and the Need for Well-Represented Collections." Current protocols vol. 1,5 (2021): e134. doi: https://doi.org/10.1002/cpz1.134
Guerra-García A, Gioia T, von Wettberg E, Logozzo G, Papa R, Bitocchi E, Bett KE. Intelligent Characterization of Lentil Genetic Resources: Evolutionary History, Genetic Diversity of Germplasm, and the Need for Well-Represented Collections. Curr Protoc. 2021 May;1(5):e134. doi: 10.1002/cpz1.134. PMID: 34004055.
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VarFish: comprehensive DNA variant analysis for diagnostics and research.

Nucleic acids research

Holtgrewe M, Stolpe O, Nieminen M, Mundlos S, Knaus A, Kornak U, Seelow D, Segebrecht L, Spielmann M, Fischer-Zirnsak B, Boschann F, Scholl U, Ehmke N, Beule D.
PMID: 32338743
Nucleic Acids Res. 2020 Jul 02;48:W162-W169. doi: 10.1093/nar/gkaa241.

VarFish is a user-friendly web application for the quality control, filtering, prioritization, analysis, and user-based annotation of DNA variant data with a focus on rare disease genetics. It is capable of processing variant call files with single or multiple...

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Holtgrewe M, Stolpe O, Nieminen M, et al. VarFish: comprehensive DNA variant analysis for diagnostics and research. Nucleic Acids Res. 2020;48:W162-W169doi: 10.1093/nar/gkaa241.
Holtgrewe, M., Stolpe, O., Nieminen, M., Mundlos, S., Knaus, A., Kornak, U., Seelow, D., Segebrecht, L., Spielmann, M., Fischer-Zirnsak, B., Boschann, F., Scholl, U., Ehmke, N., & Beule, D. (2020). VarFish: comprehensive DNA variant analysis for diagnostics and research. Nucleic acids research, 48W162-W169. https://doi.org/10.1093/nar/gkaa241
Holtgrewe, Manuel, et al. "VarFish: comprehensive DNA variant analysis for diagnostics and research." Nucleic acids research vol. 48 (2020): W162-W169. doi: https://doi.org/10.1093/nar/gkaa241
Holtgrewe M, Stolpe O, Nieminen M, Mundlos S, Knaus A, Kornak U, Seelow D, Segebrecht L, Spielmann M, Fischer-Zirnsak B, Boschann F, Scholl U, Ehmke N, Beule D. VarFish: comprehensive DNA variant analysis for diagnostics and research. Nucleic Acids Res. 2020 Jul 02;48:W162-W169. doi: 10.1093/nar/gkaa241. PMID: 32338743; PMCID: PMC7319464.
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Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis.

Genetics in medicine : official journal of the American College of Medical Genetics

Alaimo JT, Glinton KE, Liu N, Xiao J, Yang Y, Reid Sutton V, Elsea SH.
PMID: 32439973
Genet Med. 2020 Sep;22(9):1560-1566. doi: 10.1038/s41436-020-0827-0. Epub 2020 May 22.

PURPOSE: A primary barrier to improving exome sequencing diagnostic rates is the interpretation of variants of uncertain clinical significance. We aimed to determine the contribution of integrated untargeted metabolomics in the analysis of exome sequencing data by retrospective analysis...

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Alaimo JT, Glinton KE, Liu N, et al. Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis. Genet Med. 2020;22(9):1560-1566doi: 10.1038/s41436-020-0827-0.
Alaimo, J. T., Glinton, K. E., Liu, N., Xiao, J., Yang, Y., Reid Sutton, V., & Elsea, S. H. (2020). Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis. Genetics in medicine : official journal of the American College of Medical Genetics, 22(9), 1560-1566. https://doi.org/10.1038/s41436-020-0827-0
Alaimo, Joseph T, et al. "Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis." Genetics in medicine : official journal of the American College of Medical Genetics vol. 22,9 (2020): 1560-1566. doi: https://doi.org/10.1038/s41436-020-0827-0
Alaimo JT, Glinton KE, Liu N, Xiao J, Yang Y, Reid Sutton V, Elsea SH. Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis. Genet Med. 2020 Sep;22(9):1560-1566. doi: 10.1038/s41436-020-0827-0. Epub 2020 May 22. PMID: 32439973; PMCID: PMC7483344.
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Genetically modulated educational attainment and coronary disease risk.

European heart journal

Zeng L, Ntalla I, Kessler T, Kastrati A, Erdmann J, Danesh J, Watkins H, Samani NJ, Deloukas P, Schunkert H.
PMID: 31170283
Eur Heart J. 2019 Aug 01;40(29):2413-2420. doi: 10.1093/eurheartj/ehz328.

AIMS: Genetic disposition and lifestyle factors are understood as independent components underlying the risk of multiple diseases. In this study, we aim to investigate the interplay between genetics, educational attainment-an important denominator of lifestyle-and coronary artery disease (CAD) risk.METHODS...

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Zeng L, Ntalla I, Kessler T, et al. Genetically modulated educational attainment and coronary disease risk. Eur Heart J. 2019;40(29):2413-2420doi: 10.1093/eurheartj/ehz328.
Zeng, L., Ntalla, I., Kessler, T., Kastrati, A., Erdmann, J., Danesh, J., Watkins, H., Samani, N. J., Deloukas, P., & Schunkert, H. (2019). Genetically modulated educational attainment and coronary disease risk. European heart journal, 40(29), 2413-2420. https://doi.org/10.1093/eurheartj/ehz328
Zeng, Lingyao, et al. "Genetically modulated educational attainment and coronary disease risk." European heart journal vol. 40,29 (2019): 2413-2420. doi: https://doi.org/10.1093/eurheartj/ehz328
Zeng L, Ntalla I, Kessler T, Kastrati A, Erdmann J, Danesh J, Watkins H, Samani NJ, Deloukas P, Schunkert H. Genetically modulated educational attainment and coronary disease risk. Eur Heart J. 2019 Aug 01;40(29):2413-2420. doi: 10.1093/eurheartj/ehz328. PMID: 31170283; PMCID: PMC6669407.
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DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps.

JAMA

Murray MF, Evans JP, Khoury MJ.
PMID: 31808788
JAMA. 2020 Jan 28;323(4):307-308. doi: 10.1001/jama.2019.18640.

No abstract available.

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Murray MF, Evans JP, Khoury MJ. DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps. JAMA. 2020;323(4):307-308doi: 10.1001/jama.2019.18640.
Murray, M. F., Evans, J. P., & Khoury, M. J. (2020). DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps. JAMA, 323(4), 307-308. https://doi.org/10.1001/jama.2019.18640
Murray, Michael F, et al. "DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps." JAMA vol. 323,4 (2020): 307-308. doi: https://doi.org/10.1001/jama.2019.18640
Murray MF, Evans JP, Khoury MJ. DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps. JAMA. 2020 Jan 28;323(4):307-308. doi: 10.1001/jama.2019.18640. PMID: 31808788.
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Dispersal and Good Habitat Quality Promote Neutral Genetic Diversity in Metapopulations.

Bulletin of mathematical biology

Garnier J, Lafontaine P.
PMID: 33452944
Bull Math Biol. 2021 Jan 16;83(3):20. doi: 10.1007/s11538-020-00853-5.

Dispersal is a fundamental and crucial ecological process for a metapopulation to survive in heterogeneous or changing habitats. In this paper, we investigate the effect of the habitat quality and the dispersal on the neutral genetics diversity of a...

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Garnier J, Lafontaine P. Dispersal and Good Habitat Quality Promote Neutral Genetic Diversity in Metapopulations. Bull Math Biol. 2021;83(3):20doi: 10.1007/s11538-020-00853-5.
Garnier, J., & Lafontaine, P. (2021). Dispersal and Good Habitat Quality Promote Neutral Genetic Diversity in Metapopulations. Bulletin of mathematical biology, 83(3), 20. https://doi.org/10.1007/s11538-020-00853-5
Garnier, Jimmy, and Lafontaine, Pierre. "Dispersal and Good Habitat Quality Promote Neutral Genetic Diversity in Metapopulations." Bulletin of mathematical biology vol. 83,3 (2021): 20. doi: https://doi.org/10.1007/s11538-020-00853-5
Garnier J, Lafontaine P. Dispersal and Good Habitat Quality Promote Neutral Genetic Diversity in Metapopulations. Bull Math Biol. 2021 Jan 16;83(3):20. doi: 10.1007/s11538-020-00853-5. PMID: 33452944.
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The role of genetic diversity and arbuscular mycorrhizal fungal diversity in population recovery of the semi-natural grassland plant species Succisa pratensis.

BMC ecology and evolution

Van Geel M, Aavik T, Ceulemans T, Träger S, Mergeay J, Peeters G, van Acker K, Zobel M, Koorem K, Honnay O.
PMID: 34740329
BMC Ecol Evol. 2021 Nov 05;21(1):200. doi: 10.1186/s12862-021-01928-0.

BACKGROUND: Ecosystem restoration is as a critical tool to counteract the decline of biodiversity and recover vital ecosystem services. Restoration efforts, however, often fall short of meeting their goals. Although functionally important levels of biodiversity can significantly contribute to...

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Van Geel M, Aavik T, Ceulemans T, et al. The role of genetic diversity and arbuscular mycorrhizal fungal diversity in population recovery of the semi-natural grassland plant species Succisa pratensis. BMC Ecol Evol. 2021;21(1):200doi: 10.1186/s12862-021-01928-0.
Van Geel, M., Aavik, T., Ceulemans, T., Träger, S., Mergeay, J., Peeters, G., van Acker, K., Zobel, M., Koorem, K., & Honnay, O. (2021). The role of genetic diversity and arbuscular mycorrhizal fungal diversity in population recovery of the semi-natural grassland plant species Succisa pratensis. BMC ecology and evolution, 21(1), 200. https://doi.org/10.1186/s12862-021-01928-0
Van Geel, Maarten, et al. "The role of genetic diversity and arbuscular mycorrhizal fungal diversity in population recovery of the semi-natural grassland plant species Succisa pratensis." BMC ecology and evolution vol. 21,1 (2021): 200. doi: https://doi.org/10.1186/s12862-021-01928-0
Van Geel M, Aavik T, Ceulemans T, Träger S, Mergeay J, Peeters G, van Acker K, Zobel M, Koorem K, Honnay O. The role of genetic diversity and arbuscular mycorrhizal fungal diversity in population recovery of the semi-natural grassland plant species Succisa pratensis. BMC Ecol Evol. 2021 Nov 05;21(1):200. doi: 10.1186/s12862-021-01928-0. PMID: 34740329; PMCID: PMC8570031.
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COVID-19 severity, miR-21 targets, and common human genetic variation. Letter regarding the article 'Circulating cardiovascular microRNAs in critically ill COVID-19 patients'.

European journal of heart failure

Dingsdag SA, Clay OK, Quintero GA.
PMID: 34318976
Eur J Heart Fail. 2021 Nov;23(11):1986-1987. doi: 10.1002/ejhf.2317. Epub 2021 Aug 09.

No abstract available.

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Dingsdag SA, Clay OK, Quintero GA. COVID-19 severity, miR-21 targets, and common human genetic variation. Letter regarding the article 'Circulating cardiovascular microRNAs in critically ill COVID-19 patients'. Eur J Heart Fail. 2021;23(11):1986-1987doi: 10.1002/ejhf.2317.
Dingsdag, S. A., Clay, O. K., & Quintero, G. A. (2021). COVID-19 severity, miR-21 targets, and common human genetic variation. Letter regarding the article 'Circulating cardiovascular microRNAs in critically ill COVID-19 patients'. European journal of heart failure, 23(11), 1986-1987. https://doi.org/10.1002/ejhf.2317
Dingsdag, Simon A, et al. "COVID-19 severity, miR-21 targets, and common human genetic variation. Letter regarding the article 'Circulating cardiovascular microRNAs in critically ill COVID-19 patients'." European journal of heart failure vol. 23,11 (2021): 1986-1987. doi: https://doi.org/10.1002/ejhf.2317
Dingsdag SA, Clay OK, Quintero GA. COVID-19 severity, miR-21 targets, and common human genetic variation. Letter regarding the article 'Circulating cardiovascular microRNAs in critically ill COVID-19 patients'. Eur J Heart Fail. 2021 Nov;23(11):1986-1987. doi: 10.1002/ejhf.2317. Epub 2021 Aug 09. PMID: 34318976; PMCID: PMC8427028.
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Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy.

International journal of molecular sciences

Feldmeyer L, Heidemeyer K, Yawalkar N.
PMID: 27472323
Int J Mol Sci. 2016 Jul 27;17(8). doi: 10.3390/ijms17081214.

Acute generalized exanthematous pustulosis (AGEP) is a severe, usually drug-related reaction, characterized by an acute onset of mainly small non-follicular pustules on an erythematous base and spontaneous resolution usually within two weeks. Systemic involvement occurs in about 20% of...

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Feldmeyer L, Heidemeyer K, Yawalkar N. Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy. Int J Mol Sci. 2016;17(8)doi: 10.3390/ijms17081214.
Feldmeyer, L., Heidemeyer, K., & Yawalkar, N. (2016). Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy. International journal of molecular sciences, 17(8), . https://doi.org/10.3390/ijms17081214
Feldmeyer, Laurence, et al. "Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy." International journal of molecular sciences vol. 17,8 (2016). doi: https://doi.org/10.3390/ijms17081214
Feldmeyer L, Heidemeyer K, Yawalkar N. Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy. Int J Mol Sci. 2016 Jul 27;17(8). doi: 10.3390/ijms17081214. PMID: 27472323; PMCID: PMC5000612.
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Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants.

PLoS computational biology

Bagley SC, Sirota M, Chen R, Butte AJ, Altman RB.
PMID: 27115429
PLoS Comput Biol. 2016 Apr 26;12(4):e1004885. doi: 10.1371/journal.pcbi.1004885. eCollection 2016 Apr.

Patterns of disease co-occurrence that deviate from statistical independence may represent important constraints on biological mechanism, which sometimes can be explained by shared genetics. In this work we study the relationship between disease co-occurrence and commonly shared genetic architecture...

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Bagley SC, Sirota M, Chen R, et al. Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants. PLoS Comput Biol. 2016;12(4):e1004885doi: 10.1371/journal.pcbi.1004885.
Bagley, S. C., Sirota, M., Chen, R., Butte, A. J., & Altman, R. B. (2016). Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants. PLoS computational biology, 12(4), e1004885. https://doi.org/10.1371/journal.pcbi.1004885
Bagley, Steven C, et al. "Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants." PLoS computational biology vol. 12,4 (2016): e1004885. doi: https://doi.org/10.1371/journal.pcbi.1004885
Bagley SC, Sirota M, Chen R, Butte AJ, Altman RB. Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants. PLoS Comput Biol. 2016 Apr 26;12(4):e1004885. doi: 10.1371/journal.pcbi.1004885. eCollection 2016 Apr. PMID: 27115429; PMCID: PMC4846031.
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Intratumor heterogeneity: origins, clinical significance and optimal strategies for cancer treatment.

Future oncology (London, England)

Mangano A, Lianos GD, Mangano A, Boni L, Dionigi G.
PMID: 25686113
Future Oncol. 2015;11(4):561-4. doi: 10.2217/fon.14.296.

No abstract available.

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Mangano A, Lianos GD, Mangano A, et al. Intratumor heterogeneity: origins, clinical significance and optimal strategies for cancer treatment. Future Oncol. 2015;11(4):561-4doi: 10.2217/fon.14.296.
Mangano, A., Lianos, G. D., Mangano, A., Boni, L., & Dionigi, G. (2015). Intratumor heterogeneity: origins, clinical significance and optimal strategies for cancer treatment. Future oncology (London, England), 11(4), 561-4. https://doi.org/10.2217/fon.14.296
Mangano, Alberto, et al. "Intratumor heterogeneity: origins, clinical significance and optimal strategies for cancer treatment." Future oncology (London, England) vol. 11,4 (2015): 561-4. doi: https://doi.org/10.2217/fon.14.296
Mangano A, Lianos GD, Mangano A, Boni L, Dionigi G. Intratumor heterogeneity: origins, clinical significance and optimal strategies for cancer treatment. Future Oncol. 2015;11(4):561-4. doi: 10.2217/fon.14.296. PMID: 25686113.
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Host genetics and infectious disease: new tools, insights and translational opportunities.

Nature reviews. Genetics

Kwok AJ, Mentzer A, Knight JC.
PMID: 33277640
Nat Rev Genet. 2021 Mar;22(3):137-153. doi: 10.1038/s41576-020-00297-6. Epub 2020 Dec 04.

Understanding how human genetics influence infectious disease susceptibility offers the opportunity for new insights into pathogenesis, potential drug targets, risk stratification, response to therapy and vaccination. As new infectious diseases continue to emerge, together with growing levels of antimicrobial...

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Kwok AJ, Mentzer A, Knight JC. Host genetics and infectious disease: new tools, insights and translational opportunities. Nat Rev Genet. 2020;22(3):137-153doi: 10.1038/s41576-020-00297-6.
Kwok, A. J., Mentzer, A., & Knight, J. C. (2021). Host genetics and infectious disease: new tools, insights and translational opportunities. Nature reviews. Genetics, 22(3), 137-153. https://doi.org/10.1038/s41576-020-00297-6
Kwok, Andrew J, et al. "Host genetics and infectious disease: new tools, insights and translational opportunities." Nature reviews. Genetics vol. 22,3 (2021): 137-153. doi: https://doi.org/10.1038/s41576-020-00297-6
Kwok AJ, Mentzer A, Knight JC. Host genetics and infectious disease: new tools, insights and translational opportunities. Nat Rev Genet. 2021 Mar;22(3):137-153. doi: 10.1038/s41576-020-00297-6. Epub 2020 Dec 04. PMID: 33277640; PMCID: PMC7716795.
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Showing 25 to 36 of 186 entries