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Showing 25 to 36 of 233 entries
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Epigenetic regulatory modifications in genetic and sporadic frontotemporal dementia.

Expert review of neurotherapeutics

Fenoglio C, Scarpini E, Galimberti D.
PMID: 29799291
Expert Rev Neurother. 2018 Jun;18(6):469-475. doi: 10.1080/14737175.2018.1481389. Epub 2018 Jun 05.

INTRODUCTION: Epigenetic modifications have recently been linked to neurodegenerative diseases, such as frontotemporal dementia (FTD), which represents the second most common form of dementia in adulthood after Alzheimer's disease (AD). Epigenetic regulation occurs at different cellular levels and serve...

EWAS Atlas: a curated knowledgebase of epigenome-wide association studies.

Nucleic acids research

Li M, Zou D, Li Z, Gao R, Sang J, Zhang Y, Li R, Xia L, Zhang T, Niu G, Bao Y, Zhang Z.
PMID: 30364969
Nucleic Acids Res. 2019 Jan 08;47:D983-D988. doi: 10.1093/nar/gky1027.

Epigenome-Wide Association Study (EWAS) has become increasingly significant in identifying the associations between epigenetic variations and different biological traits. In this study, we develop EWAS Atlas (http://bigd.big.ac.cn/ewas), a curated knowledgebase of EWAS that provides a comprehensive collection of EWAS...

Epigenetics: Therapy-induced transcription is cryptically widespread.

Nature reviews. Cancer

Burgess DJ.
PMID: 28706265
Nat Rev Cancer. 2017 Aug;17(8):456. doi: 10.1038/nrc.2017.57. Epub 2017 Jul 14.

No abstract available.

Epigenetics as a mechanism linking developmental exposures to long-term toxicity.

Environment international

Barouki R, Melén E, Herceg Z, Beckers J, Chen J, Karagas M, Puga A, Xia Y, Chadwick L, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, Nohara K.
PMID: 29499450
Environ Int. 2018 May;114:77-86. doi: 10.1016/j.envint.2018.02.014. Epub 2018 Feb 27.

A variety of experimental and epidemiological studies lend support to the Developmental Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for mid- and long-term effects of early-life exposures remain unclear. Epigenetic alterations such as changes...

Cancer epigenetics: Therapy-induced transcription is cryptically widespread.

Nature reviews. Genetics

Burgess DJ.
PMID: 28649134
Nat Rev Genet. 2017 Aug;18(8):455. doi: 10.1038/nrg.2017.53. Epub 2017 Jun 26.

No abstract available.

Epigenetics: Getting instructions from mum.

Nature reviews. Genetics

Strzyz P.
PMID: 28781364
Nat Rev Genet. 2017 Sep;18(9):513. doi: 10.1038/nrg.2017.64. Epub 2017 Aug 07.

No abstract available.

Developmental Origins, Epigenetics, and Equity: Moving Upstream.

Maternal and child health journal

Wallack L, Thornburg K.
PMID: 27029539
Matern Child Health J. 2016 May;20(5):935-40. doi: 10.1007/s10995-016-1970-8.

The Developmental Origins of Health and Disease and the related science of epigenetics redefines the meaning of what constitutes upstream approaches to significant social and public health problems. An increasingly frequent concept being expressed is "When it comes to...

Epigenetics and developmental psychiatry.

The International journal of social psychiatry

Peedicayil J.
PMID: 28504044
Int J Soc Psychiatry. 2017 Jun;63(4):378. doi: 10.1177/0020764017693656. Epub 2017 Mar 07.

No abstract available.

Epigenetics for dummies.

Postgraduate medical journal

Launer J.
PMID: 26917777
Postgrad Med J. 2016 Mar;92(1085):183-4. doi: 10.1136/postgradmedj-2016-133993.

No abstract available.

[Current methods in molecular pathology].

Therapeutische Umschau. Revue therapeutique

Hench J, Jermann PM, Bratic Hench I, Matter MS.
PMID: 31498035
Ther Umsch. 2019 Sep;76(4):173-178. doi: 10.1024/0040-5930/a001081.

Current methods in molecular pathology

Targeting epigenetic modifications as a potential therapeutic option for diabetic retinopathy.

Journal of cellular physiology

Kumari N, Karmakar A, Ganesan SK.
PMID: 31531859
J Cell Physiol. 2020 Mar;235(3):1933-1947. doi: 10.1002/jcp.29180. Epub 2019 Sep 17.

Diabetic retinopathy (DR) is the leading cause of visual impairment in adults of working age (20-65 years) in developed countries. The metabolic memory phenomena (persistent effect of a glycemic insult even after retrieved) associated with it has increased the...

Epigenetic Applications in Adverse Outcome Pathways and Environmental Risk Evaluation.

Environmental health perspectives

Angrish MM, Allard P, McCullough SD, Druwe IL, Helbling Chadwick L, Hines E, Chorley BN.
PMID: 29669403
Environ Health Perspect. 2018 Apr 12;126(4):045001. doi: 10.1289/EHP2322.

BACKGROUND: The epigenome may be an important interface between environmental chemical exposures and human health. However, the links between epigenetic modifications and health outcomes are often correlative and do not distinguish between cause and effect or common-cause relationships. The...

Showing 25 to 36 of 233 entries