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Showing 34369 to 420 of 420 entries
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Exploiting adversarial transfer learning for adverse drug reaction detection from texts.

Journal of biomedical informatics

Li Z, Yang Z, Luo L, Xiang Y, Lin H.
PMID: 32335225
J Biomed Inform. 2020 Jun;106:103431. doi: 10.1016/j.jbi.2020.103431. Epub 2020 Apr 24.

Adverse Drug Reactions (ADRs) are extremely hazardous to patients. ADR Detection aims to automatically determine whether a sentence is related to an ADR, which is a fundamental study for public health monitoring tasks, particularly for pharmacovigilance. Benchmark corpora are...

Unanswered Questions.

Deutsches Arzteblatt international

Lichtenstein B.
PMID: 30406747
Dtsch Arztebl Int. 2018 Oct 12;115(41):682. doi: 10.3238/arztebl.2018.0682a.

No abstract available.

In Reply.

Deutsches Arzteblatt international

Dubrall D, Sachs B.
PMID: 30406748
Dtsch Arztebl Int. 2018 Oct 12;115(41):682. doi: 10.3238/arztebl.2018.0682b.

No abstract available.

The economic burden of preventable adverse drug reactions: a systematic review of observational studies.

Expert opinion on drug safety

Formica D, Sultana J, Cutroneo PM, Lucchesi S, Angelica R, Crisafulli S, Ingrasciotta Y, Salvo F, Spina E, Trifirò G.
PMID: 29952667
Expert Opin Drug Saf. 2018 Jul;17(7):681-695. doi: 10.1080/14740338.2018.1491547. Epub 2018 Jul 03.

INTRODUCTION: Adverse drug reactions (ADRs) are an important cause of morbidity and mortality worldwide. They are associated with healthcare costs due to hospital admissions or prolonged length of stay, as well as additional interventions. The aim of this study...

Prevention of drug-related complications in cystic fibrosis.

Current opinion in pulmonary medicine

van der Meer R, Touw DJ, Heijerman HGM.
PMID: 31503211
Curr Opin Pulm Med. 2019 Nov;25(6):666-673. doi: 10.1097/MCP.0000000000000625.

PURPOSE OF REVIEW: Due to continuous development of new drugs and better treatment strategies, survival of patients with cystic fibrosis has changed dramatically. Recently, targeted therapy of cystic fibrosis transmembrane conductance regulator (CFTR) modulators have become available. Despite these...

Supporting Clinicians After Adverse Events: Development of a Clinician Peer Support Program.

Journal of patient safety

Lane MA, Newman BM, Taylor MZ, OʼNeill M, Ghetti C, Woltman RM, Waterman AD.
PMID: 29878948
J Patient Saf. 2018 Sep;14(3):e56-e60. doi: 10.1097/PTS.0000000000000508.

BACKGROUND: Many healthcare organizations have developed processes for supporting the emotional needs of patients and their families after medical errors or adverse events. However, the clinicians involved in such events may become "second victims" and frequently experience emotional harm...

Data Mining for Adverse Drug Events: Impact on Six Learning Styles.

Computers, informatics, nursing : CIN

[No authors listed]
PMID: 31094918
Comput Inform Nurs. 2019 May;37(5):283-284. doi: 10.1097/01.NCN.0000557763.30046.7d.

No abstract available.

The 10th International Congress on Cutaneous Adverse Drug Reactions, Shimane, Japan, 2018: Focus on New Discoveries.

Drug safety

Olteanu C, Shear NH, Morita E, Chung WH, Niihara H, Matsukura S, Hashimoto R, Dodiuk-Gad RP.
PMID: 31037651
Drug Saf. 2019 Jun;42(6):797-801. doi: 10.1007/s40264-019-00818-1.

No abstract available.

What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?.

The Journal of surgical research

Zarrinpar A, David Cheng TY, Huo Z.
PMID: 31653413
J Surg Res. 2020 Feb;246:599-604. doi: 10.1016/j.jss.2019.09.053. Epub 2019 Oct 22.

As more and more health systems have converted to the use of electronic health records, the amount of searchable and analyzable data is exploding. This includes not just provider or laboratory created data but also data collected by instruments,...

A Review of Drug Side Effect Identification Methods.

Current pharmaceutical design

Deng S, Sun Y, Zhao T, Hu Y, Zang T.
PMID: 32532187
Curr Pharm Des. 2020;26(26):3096-3104. doi: 10.2174/1381612826666200612163819.

Drug side effects have become an important indicator for evaluating the safety of drugs. There are two main factors in the frequent occurrence of drug safety problems; on the one hand, the clinical understanding of drug side effects is...

Signals of adverse drug reactions communicated by pharmacovigilance stakeholders: protocol for a scoping review of the global literature.

Systematic reviews

Sartori D, Aronson JK, Onakpoya IJ.
PMID: 32791982
Syst Rev. 2020 Aug 13;9(1):180. doi: 10.1186/s13643-020-01429-z.

BACKGROUND: Signals of adverse drug reactions (ADRs) form the basis of some regulatory risk-minimization actions in pharmacovigilance. Reviews of limited scope have highlighted that such signals are mostly supported by reports of ADRs or multiple types of evidence. The...

XenoNet: Inference and Likelihood of Intermediate Metabolite Formation.

Journal of chemical information and modeling

Flynn NR, Dang NL, Ward MD, Swamidass SJ.
PMID: 32525671
J Chem Inf Model. 2020 Jul 27;60(7):3431-3449. doi: 10.1021/acs.jcim.0c00361. Epub 2020 Jun 29.

Drug metabolism is a common cause of adverse drug reactions. Drug molecules can be metabolized into reactive metabolites, which can conjugate to biomolecules, like protein and DNA, in a process termed bioactivation. To mitigate adverse reactions caused by bioactivation,...

Showing 34369 to 420 of 420 entries