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Showing 13 to 15 of 15 entries
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Drug discovery: engineering drug combinations.

Nature chemical biology

Dixon SJ, Stockwell BR.
PMID: 20404820
Nat Chem Biol. 2010 May;6(5):318-9. doi: 10.1038/nchembio.353.

No abstract available.

Network-based target ranking for polypharmacological therapies.

Journal of biomedical informatics

Vitali F, Mulas F, Marini P, Bellazzi R.
PMID: 23850841
J Biomed Inform. 2013 Oct;46(5):876-81. doi: 10.1016/j.jbi.2013.06.015. Epub 2013 Jul 10.

With the growing understanding of complex diseases, the focus of drug discovery has shifted from the well-accepted "one target, one drug" model, to a new "multi-target, multi-drug" model, aimed at systemically modulating multiple targets. In this context, polypharmacology has...

Response to "Three drugs are unnecessary for treating paucibacillary leprosy-A critique of the WHO guidelines".

PLoS neglected tropical diseases

Kumar B, Thakur V, Narang T, Dogra S.
PMID: 32497033
PLoS Negl Trop Dis. 2020 Jun 04;14(6):e0008169. doi: 10.1371/journal.pntd.0008169. eCollection 2020 Jun.

No abstract available.

Showing 13 to 15 of 15 entries