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Showing 13 to 24 of 59 entries
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Setting the benchmark.

The Journal of thoracic and cardiovascular surgery

Sundt TM.
PMID: 27085614
J Thorac Cardiovasc Surg. 2016 May;151(5):1339. doi: 10.1016/j.jtcvs.2016.03.005. Epub 2016 Mar 10.

No abstract available.

Analysis of COVID-19 vaccines: Types, thoughts, and application.

Journal of clinical laboratory analysis

Han X, Xu P, Ye Q.
PMID: 34396586
J Clin Lab Anal. 2021 Sep;35(9):e23937. doi: 10.1002/jcla.23937. Epub 2021 Aug 15.

OBJECTIVE: To deal with COVID-19, various countries have made many efforts, including the research and development of vaccines. The purpose of this manuscript was to summarize the development, application, and problems of COVID-19 vaccines.METHODS: This article reviewed the existing...

Intensifying insulin therapy in type 2 diabetes mellitus: dosing options for insulin analogue premixes.

Clinical therapeutics

Tibaldi JM.
PMID: 22030443
Clin Ther. 2011 Nov;33(11):1630-42. doi: 10.1016/j.clinthera.2011.09.019. Epub 2011 Oct 26.

BACKGROUND: As the diabetes epidemic expands, health care providers need more options to achieve glycemic control. Insulin analogue premixes provide basal and prandial insulin with 1 injection.OBJECTIVES: The aim of this review was to provide an overview of the...

Pediatric dose selection.

Clinical pharmacology and therapeutics

Abernethy DR, Burckart GJ.
PMID: 20160747
Clin Pharmacol Ther. 2010 Mar;87(3):270-1. doi: 10.1038/clpt.2009.292.

Selection of a drug dose in pediatrics is generally based on no or incomplete pharmacokinetic data. Traditionally, allometric, or scaling, techniques have been used; however, they have inherent limitations and may not make optimal use of the drug-specific clinical...

[Application of pharmacometrics in personalized therapy in children].

Zhonghua er ke za zhi = Chinese journal of pediatrics

Hao G, Zheng Y, Evelyne JA, Zhao W.
PMID: 26757963
Zhonghua Er Ke Za Zhi. 2015 Sep;53(9):647-9.

No abstract available.

Modeling for regulatory purposes (risk and safety assessment).

Methods in molecular biology (Clifton, N.J.)

El-Masri H.
PMID: 23086847
Methods Mol Biol. 2013;930:297-303. doi: 10.1007/978-1-62703-059-5_13.

Chemicals provide many key building blocks that are converted into end-use products or used in industrial processes to make products that benefit society. Ensuring the safety of chemicals and their associated products is a key regulatory mission. Current processes...

Evidence-based drug treatment for special patient populations through model-based approaches.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Krekels EHJ, van Hasselt JGC, van den Anker JN, Allegaert K, Tibboel D, Knibbe CAJ.
PMID: 28502674
Eur J Pharm Sci. 2017 Nov 15;109:S22-S26. doi: 10.1016/j.ejps.2017.05.022. Epub 2017 May 11.

The majority of marketed drugs remain understudied in some patient populations such as pregnant women, paediatrics, the obese, the critically-ill, and the elderly. As a consequence, currently used dosing regimens may not assure optimal efficacy or minimal toxicity in...

Environmental hormesis and its fundamental biological basis: Rewriting the history of toxicology.

Environmental research

Agathokleous E, Kitao M, Calabrese EJ.
PMID: 29734028
Environ Res. 2018 Aug;165:274-278. doi: 10.1016/j.envres.2018.04.034. Epub 2018 May 07.

It has long been debated whether a little stress may be "good" for you. Extensive evidence has now sufficiently accumulated demonstrating that low doses of a vast range of chemical and physical agents induce protective/beneficial effects while the opposite...

A generally useful modification of ALLFIT that facilitates the fitting of null equations to dose-response curves.

Trends in pharmacological sciences

Mackay D.
PMID: 3245085
Trends Pharmacol Sci. 1988 Apr;9(4):121-2. doi: 10.1016/0165-6147(88)90189-7.

No abstract available.

Linking Exome Sequencing Data with Drug Response Aberrations.

Studies in health technology and informatics

Kyriakidis K, Charalampidou A, Natsiavas P, Vizirianakis IS, Malousi A.
PMID: 31438372
Stud Health Technol Inform. 2019 Aug 21;264:1845-1846. doi: 10.3233/SHTI190677.

Next-generation sequencing has prompted the development of numerous -omics applications. Along with experimental procedures, various computational pipelines became available to address the inherent complexities concerning the volume and quality of data. These pipelines are effective and routinely applied; however,...

Solving the problem of dose optimization of children's medicines.

Expert review of clinical pharmacology

McWilliam SJ, Hawcutt DB.
PMID: 29355041
Expert Rev Clin Pharmacol. 2018 Mar;11(3):205-208. doi: 10.1080/17512433.2018.1431528. Epub 2018 Jan 30.

No abstract available.

[Bonferroni-Holm sequential test procedure].

Zeitschrift fur Gastroenterologie

Sonnenberg A.
PMID: 4090570
Z Gastroenterol. 1985 Dec;23(12):703-4.

No abstract available.

Showing 13 to 24 of 59 entries