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Showing 13 to 24 of 67 entries
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[Carcinogenesis high molecular weight substances in vivo].

Saishin igaku. Modern medicine

Naora H, Endo H.
PMID: 5684908
Saishin Igaku. 1968 Mar 10;23(3):415-6.

No abstract available.

Pyrococcus furiosus Argonaute-mediated nucleic acid detection.

Chemical communications (Cambridge, England)

He R, Wang L, Wang F, Li W, Liu Y, Li A, Wang Y, Mao W, Zhai C, Ma L.
PMID: 31589231
Chem Commun (Camb). 2019 Oct 31;55(88):13219-13222. doi: 10.1039/c9cc07339f.

We demonstrate that short single-stranded DNA generated by Pyrococcus furiosus Argonaute (PfAgo) can initiate a second round of cleavage. Based on this principle, we established a molecular diagnostic method, termed PfAgo-mediated Nucleic acid Detection (PAND). This method could detect...

Concentration effects on capture rate and translocation configuration of nanopore-based DNA detection.

Electrophoresis

Zhang Y, Zhao J, Kan Y, Ji R, Pan J, Huang W, Xu Z, Si W, Sha J.
PMID: 32529653
Electrophoresis. 2020 Sep;41(16):1523-1528. doi: 10.1002/elps.202000016. Epub 2020 Jun 11.

Nanopore is a kind of powerful tool to detect single molecules and investigate fundamental biological processes. In biological cells or real detection systems, concentration of DNA molecules is various. Here, we report an experimental study of the effects of...

Imaging with DNA.

Nature methods

Strack R.
PMID: 31363210
Nat Methods. 2019 Aug;16(8):675. doi: 10.1038/s41592-019-0524-6.

No abstract available.

Microfluidic Platform for Next-Generation Sequencing Library Preparation with Low-Input Samples.

Analytical chemistry

Murphy TW, Hsieh YP, Zhu B, Naler LB, Lu C.
PMID: 31894965
Anal Chem. 2020 Feb 04;92(3):2519-2526. doi: 10.1021/acs.analchem.9b04086. Epub 2020 Jan 14.

Advances in next-generation sequencing (NGS) have made available a wealth of information that had previously been inaccessible to researchers and clinicians. NGS has been applied to understand genomic, transcriptomic, and epigenomic changes and gained traction as a significant tool...

Integrated microfluidic systems for DNA analysis.

Topics in current chemistry

Njoroge SK, Chen HW, Witek MA, Soper SA.
PMID: 21607848
Top Curr Chem. 2011;304:203-60. doi: 10.1007/128_2011_153.

The potential utility of genome-related research in terms of evolving basic discoveries in biology has generated widespread use of DNA diagnostics and DNA forensics and driven the accelerated development of fully integrated microfluidic systems for genome processing. To produce...

On-channel base stacking in microchip capillary gel electrophoresis for high-sensitivity DNA fragment analysis.

Journal of chromatography. A

Kim DK, Kang SH.
PMID: 15729827
J Chromatogr A. 2005 Jan 28;1064(1):121-7. doi: 10.1016/j.chroma.2004.12.045.

We evaluated a novel strategy for high-sensitivity DNA fragment analysis in a conventional glass double-T microfluidic chip. The microchip allows for a DNA on-channel concentration based on base stacking (BS) with a microchip capillary gel electrophoretic (MCGE) separation step...

Multiple enzyme layers on carbon nanotubes for electrochemical detection down to 80 DNA copies.

Analytical chemistry

Munge B, Liu G, Collins G, Wang J.
PMID: 16013886
Anal Chem. 2005 Jul 15;77(14):4662-6. doi: 10.1021/ac050132g.

Signal amplification using enzyme multilayers on carbon nanotube (CNT) templates is shown to yield a remarkably sensitive electrochemical detection of proteins and nucleic acids. The electrostatic layer-by-layer (LBL) self-assembly onto CNT carriers maximizes the ratio of enzyme tags per...

Ovotesticular disorder of sexual development (true hermaphroditism).

Urology

Berger-Zaslav AL, Mehta L, Jacob J, Mercado T, Gadi I, Tepperberg JH, Palmer LS.
PMID: 18822450
Urology. 2009 Feb;73(2):293-6. doi: 10.1016/j.urology.2008.08.428. Epub 2008 Sep 26.

OBJECTIVES: To determine the mechanism for the 46,XX/46,XY karyotype observed in a patient with an ovotesticular disorder of sexual development (ie, true hermaphroditism).METHODS: Cytogenetic, molecular cytogenetic, and molecular DNA analyses were performed on the blood, skin, and left and...

Integrating amperometric detection with electrophoresis microchip devices for biochemical assays: recent developments.

Talanta

Ghanim MH, Abdullah MZ.
PMID: 21645665
Talanta. 2011 Jul 15;85(1):28-34. doi: 10.1016/j.talanta.2011.04.069. Epub 2011 May 05.

Recent advances in microfluidic systems, particularly in the Micro Total Analysis System (μTAS) or Lab On a Chip (LOC), drive the current analysis tools and equipment towards miniaturization, rapid at-line testing and mobility. The state-of-the-art microfluidic technology targets a...

Pimp my spec!.

BioTechniques

Perkel JM.
PMID: 23227984
Biotechniques. 2012 Dec;53(6):339-43. doi: 10.2144/000113960.

No abstract available.

Using Environmental DNA for Invasive Species Surveillance and Monitoring.

Methods in molecular biology (Clifton, N.J.)

Mahon AR, Jerde CL.
PMID: 27460374
Methods Mol Biol. 2016;1452:131-42. doi: 10.1007/978-1-4939-3774-5_8.

The method employed for environmental DNA (eDNA) surveillance for detection and monitoring of rare species in aquatic systems has evolved dramatically since its first large-scale applications. Both active (targeted) and passive (total diversity) surveillance methods provide helpful information for...

Showing 13 to 24 of 67 entries