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Showing 37 to 48 of 64 entries
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On the localization of genes on certain autosomes of man through chromosome aberrations. 3. Exclusion of the possibility of gene assignment.

Humangenetik

Bender K, Burckhardt K.
PMID: 5488998
Humangenetik. 1970;9(1):75-85. doi: 10.1007/BF00696016.

No abstract available.

Psychiatric genetics: a genetic basis for health?.

Current biology : CB

Flint J, Goodwin G.
PMID: 10330369
Curr Biol. 1999 May 06;9(9):R326-8. doi: 10.1016/s0960-9822(99)80204-8.

Attempts to map the genes for psychotic illnesses have been fraught with problems. Studying why some family members do not become ill might prove to be a more successful strategy.

Limits on fine mapping of complex traits.

American journal of human genetics

Kruglyak L, Lander ES.
PMID: 8651271
Am J Hum Genet. 1996 May;58(5):1092-3.

No abstract available.

From Genetic Mapping to Molecular Breeding: Genomics Have Paved the Highway.

Molecular plant

Huang X.
PMID: 27268287
Mol Plant. 2016 Jul 06;9(7):959-60. doi: 10.1016/j.molp.2016.06.001. Epub 2016 Jun 04.

No abstract available.

eQTL analysis in humans.

Methods in molecular biology (Clifton, N.J.)

Franke L, Jansen RC.
PMID: 19763935
Methods Mol Biol. 2009;573:311-28. doi: 10.1007/978-1-60761-247-6_17.

Improving human health is a major aim of medical research, but it requires that variation between individuals be taken into account since each person carries a different combination of gene variants and is exposed to different environmental conditions, which...

From sextant to GPS: twenty-five years of mapping the genome with ChIP.

Journal of cellular biochemistry

Wacker DA, Kim TH.
PMID: 19180576
J Cell Biochem. 2009 May 01;107(1):6-10. doi: 10.1002/jcb.22060.

Since its inception, ChIP technology has evolved immensely. Technological advances have improved its specificity and sensitivity, its scale has expanded to a genome-wide level, and its relative ease of use has made it a virtually ubiquitous tool. This year...

The genetic map of finger millet, Eleusine coracana.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Dida MM, Srinivasachary, Ramakrishnan S, Bennetzen JL, Gale MD, Devos KM.
PMID: 17103137
Theor Appl Genet. 2007 Jan;114(2):321-32. doi: 10.1007/s00122-006-0435-7. Epub 2006 Nov 14.

Restriction fragment length polymorphism (RFLP), amplified fragment length polymorphism (AFLP), expressed-sequenced tag (EST), and simple sequence repeat (SSR) markers were used to generate a genetic map of the tetraploid finger millet (Eleusine coracana subsp. coracana) genome (2n = 4x...

Puzzling over orphan enzymes.

Cellular and molecular life sciences : CMLS

Lespinet O, Labedan B.
PMID: 16465439
Cell Mol Life Sci. 2006 Mar;63(5):517-23. doi: 10.1007/s00018-005-5520-6.

Despite the current availability of several hundreds of thousands of amino acid sequences, more than 39% of the well-defined enzyme activities (EC numbers) are not associated with any sequence in major public databases. This wide gap separating knowledge of...

Gene mappers form collaborations.

JAMA

Marwick C, Merz B.
PMID: 3172412
JAMA. 1988 Nov 04;260(17):2477.

No abstract available.

QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics.

BMC bioinformatics

O'Reilly PG, Wen Q, Bankhead P, Dunne PD, McArt DG, McPherson S, Hamilton PW, Mills KI, Zhang SD.
PMID: 27143038
BMC Bioinformatics. 2016 May 04;17(1):198. doi: 10.1186/s12859-016-1062-1.

BACKGROUND: Gene expression connectivity mapping has proven to be a powerful and flexible tool for research. Its application has been shown in a broad range of research topics, most commonly as a means of identifying potential small molecule compounds,...

[Recent progress in gene mapping through high-throughput sequencing technology and forward genetic approaches].

Yi chuan = Hereditas

Lu CR, Zou CS, Song GL.
PMID: 26266780
Yi Chuan. 2015 Aug;37(8):765-76. doi: 10.16288/j.yczz.15-068.

Traditional gene mapping using forward genetic approaches is conducted primarily through construction of a genetic linkage map, the process of which is tedious and time-consuming, and often results in low accuracy of mapping and large mapping intervals. With the...

Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments.

Nature biotechnology

Wills QF, Livak KJ, Tipping AJ, Enver T, Goldson AJ, Sexton DW, Holmes C.
PMID: 23873083
Nat Biotechnol. 2013 Aug;31(8):748-52. doi: 10.1038/nbt.2642. Epub 2013 Jul 21.

Gene expression in multiple individual cells from a tissue or culture sample varies according to cell-cycle, genetic, epigenetic and stochastic differences between the cells. However, single-cell differences have been largely neglected in the analysis of the functional consequences of...

Showing 37 to 48 of 64 entries