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Showing 13 to 24 of 28 entries
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Preclinical translation of exosomes derived from mesenchymal stem/stromal cells.

Stem cells (Dayton, Ohio)

Elahi FM, Farwell DG, Nolta JA, Anderson JD.
PMID: 31381842
Stem Cells. 2020 Jan;38(1):15-21. doi: 10.1002/stem.3061. Epub 2019 Oct 01.

Exosomes are nanovesicles secreted by virtually all cells. Exosomes mediate the horizontal transfer of various macromolecules previously believed to be cell-autonomous in nature, including nonsecretory proteins, various classes of RNA, metabolites, and lipid membrane-associated factors. Exosomes derived from mesenchymal...

[Drugs and the culturing of hepatocytes].

Bulletin de l'Academie nationale de medecine

Bourel M, Guillouzo A, Guguen-Guillouzo C.
PMID: 2790528
Bull Acad Natl Med. 1989 Apr;173(4):409-12; discussion 412-4.

Two model systems are described for studying isolated hepatocytes in vitro: pure culture for short-term designs and co-culture with epithelial rat liver cells (for long duration procedures). Acute or chronic liver toxicities are discussed as well as indirect toxicities....

[Abstracts of reports presented at the working meeting of the Committee for Cell Culture and the Section on Tissue Culture of the Czech and Slovak Oncology Societies of the J.E. Purkinje Medical Society. Stráznice, 26-29 May 1986].

Ceskoslovenska fysiologie

[No authors listed]
PMID: 3581206
Cesk Fysiol. 1987;36(2):159-79.

No abstract available.

[Liver cell culture and physiopathology of the liver].

Nihon rinsho. Japanese journal of clinical medicine

Nagamori S, Fujise K, Hasumura S, Kameda H.
PMID: 691698
Nihon Rinsho. 1978 May;2208-9.

No abstract available.

Time delay in simple chemostat models.

Biotechnology and bioengineering

MacDonald N.
PMID: 1268333
Biotechnol Bioeng. 1976 Jun;18(6):805-12. doi: 10.1002/bit.260180604.

The models of Monod and Williams, for the growth of unicellular organisms in chemostats, give strongly damped transients in the biomass and cell number when the flow rate of the chemostat is changed. A simple trick is used to...

Approaches to the problem of metabolic heterogeneity in the kidney.

The International journal of biochemistry

Guder WG, Ross BD.
PMID: 7399008
Int J Biochem. 1980;12(1):1-2. doi: 10.1016/0020-711x(80)90032-4.

No abstract available.

A potential platform for developing 3D tubular scaffolds for paediatric organ development.

Journal of materials science. Materials in medicine

de Mel A, Yap T, Cittadella G, Hale LR, Maghsoudlou P, de Coppi P, Birchall MA, Seifalian AM.
PMID: 25737129
J Mater Sci Mater Med. 2015 Mar;26(3):141. doi: 10.1007/s10856-015-5477-4. Epub 2015 Mar 04.

Children suffer from damaged or loss of hollow organs i.e. trachea, oesophagus or arteries from birth defects or diseases. Generally these organs possess an outer matrix consisting of collagen, elastin, and cells such as smooth muscle cells (SMC) and...

From Micro to Macro: The Hierarchical Design in a Micropatterned Scaffold for Cell Assembling and Transplantation.

Advanced materials (Deerfield Beach, Fla.)

Wang K, Wang X, Han C, Hou W, Wang J, Chen L, Luo Y.
PMID: 28066985
Adv Mater. 2017 Jan;29(2). doi: 10.1002/adma.201604600. Epub 2016 Nov 07.

A microwell-patterned membranous scaffold that integrates nano- and microscale topographical characteristics based on polyurethane is fabricated for transplanting syngeneic islets and allogeneic mesenchymal stem cells into diabetic rodents. The scaffold effectively allows for assembling of single cells/microtissues, enables the...

Metabolic profiling using HPLC allows classification of drugs according to their mechanisms of action in HL-1 cardiomyocytes.

Toxicology and applied pharmacology

Strigun A, Wahrheit J, Beckers S, Heinzle E, Noor F.
PMID: 21320520
Toxicol Appl Pharmacol. 2011 Apr 15;252(2):183-91. doi: 10.1016/j.taap.2011.02.008. Epub 2011 Feb 12.

Along with hepatotoxicity, cardiotoxic side effects remain one of the major reasons for drug withdrawals and boxed warnings. Prediction methods for cardiotoxicity are insufficient. High content screening comprising of not only electrophysiological characterization but also cellular molecular alterations are...

Gradient generation platforms: new directions for an established microfluidic technology.

Lab on a chip

Berthier E, Beebe DJ.
PMID: 25008971
Lab Chip. 2014 Sep 07;14(17):3241-7. doi: 10.1039/c4lc00448e.

Microscale platforms are enabling for cell-based studies as they allow the recapitulation of physiological conditions such as extracellular matrix (ECM) configurations and soluble factors interactions. Gradient generation platforms have been one of the few applications of microfluidics that have...

Analysis of protein changes using two-dimensional difference gel electrophoresis.

Methods in molecular biology (Clifton, N.J.)

Gao W.
PMID: 24623216
Methods Mol Biol. 2014;1105:17-30. doi: 10.1007/978-1-62703-739-6_2.

A protocol for protein analysis using two-dimensional difference gel electrophoresis (2D-DIGE) is described. 2D-DIGE is one of the most popular and versatile methods of protein separation among rapidly increasing proteomics technologies. Similar to traditional two-dimensional polyacrylamide gel electrophoresis (2D-PAGE),...

Human Genetic Mutant Cell Repository.

Cytogenetics and cell genetics

[No authors listed]
PMID: 4780771
Cytogenet Cell Genet. 1973;12(5):367-73. doi: 10.1159/000130475.
Free Article

No abstract available.

Showing 13 to 24 of 28 entries