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Showing 37 to 48 of 1480 entries
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Aggression Addiction and Relapse: A New Frontier in Psychiatry.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Golden SA, Shaham Y.
PMID: 29192664
Neuropsychopharmacology. 2018 Jan;43(1):224-225. doi: 10.1038/npp.2017.173.

No abstract available.

Emerging Advances in Nanotheranostics with Intelligent Bioresponsive Systems.

Theranostics

Wang J, Tao W, Chen X, Farokhzad OC, Liu G.
PMID: 29109787
Theranostics. 2017 Sep 05;7(16):3915-3919. doi: 10.7150/thno.21317. eCollection 2017.

The confluence of therapeutics and diagnostics based on the advantages of nanotechnology offers significant opportunities for personalized and precision medicine. Intelligent nanotheranostics based on bioresponsive systems have recently emerged and offer the promise of high specificity and efficiency via...

Results Reporting for Trials With the Same Sponsor, Drug, and Condition in ClinicalTrials.gov and Peer-Reviewed Publications.

JAMA internal medicine

Fain KM, Rajakannan T, Tse T, Williams RJ, Zarin DA.
PMID: 29532058
JAMA Intern Med. 2018 Jul 01;178(7):990-992. doi: 10.1001/jamainternmed.2018.0263.

No abstract available.

"If the Shoe Fits …": The Hierarchical Structure of Psychopathology and Psychiatric Neuroimaging.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Dickinson D.
PMID: 29560917
Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 May;2(4):303-304. doi: 10.1016/j.bpsc.2017.03.015. Epub 2017 Apr 28.

No abstract available.

Biocuration workflows and text mining: overview of the BioCreative 2012 Workshop Track II.

Database : the journal of biological databases and curation

Lu Z, Hirschman L.
PMID: 23160416
Database (Oxford). 2012 Nov 17;2012:bas043. doi: 10.1093/database/bas043. Print 2012.

Manual curation of data from the biomedical literature is a rate-limiting factor for many expert curated databases. Despite the continuing advances in biomedical text mining and the pressing needs of biocurators for better tools, few existing text-mining tools have...

SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics.

Bioinformatics (Oxford, England)

Song L, Liu A, Shi J.
PMID: 30911754
Bioinformatics. 2019 Oct 15;35(20):4038-4044. doi: 10.1093/bioinformatics/btz176.

MOTIVATION: Polygenic risk score (PRS) methods based on genome-wide association studies (GWAS) have a potential for predicting the risk of developing complex diseases and are expected to become more accurate with larger training datasets and innovative statistical methods. The...

When the Minimal Becomes Measurable.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Hourigan CS, Goswami M, Battiwalla M, Barrett AJ, Sheela S, Karp JE, Lai C.
PMID: 27185839
J Clin Oncol. 2016 Jul 20;34(21):2557-8. doi: 10.1200/JCO.2016.67.6395. Epub 2016 May 16.

No abstract available.

Neurodevelopmental Characterization of Young Children Diagnosed with Niemann-Pick Disease, Type C1.

Journal of developmental and behavioral pediatrics : JDBP

Thurm A, Chlebowski C, Joseph L, Farmer C, Adedipe D, Weiss M, Wiggs E, Farhat N, Bianconi S, Berry-Kravis E, Porter FD.
PMID: 32073546
J Dev Behav Pediatr. 2020 Jun/Jul;41(5):388-396. doi: 10.1097/DBP.0000000000000785.

OBJECTIVE: Niemann-Pick disease type C1 (NPC1) is a lysosomal storage disease characterized by progressive neurodegeneration, with the age of diagnosis ranging from the prenatal period through adulthood. Although neurological symptoms usually precede genetic diagnosis, they do not necessarily prompt...

Viral non-coding RNAs: Stealth strategies in the tug-of-war between humans and herpesviruses.

Seminars in cell & developmental biology

Tagawa T, Serquiña A, Kook I, Ziegelbauer J.
PMID: 32631785
Semin Cell Dev Biol. 2021 Mar;111:135-147. doi: 10.1016/j.semcdb.2020.06.015. Epub 2020 Jul 03.

Oncogenic DNA viruses establish lifelong infections in humans, and they cause cancers, often in immunocompromised patients, despite anti-viral immune surveillance targeted against viral antigens. High-throughput sequencing techniques allowed the field to identify novel viral non-coding RNAs (ncRNAs). ncRNAs are...

Challenges to informed consent for exome sequencing: A best-worst scaling experiment.

Journal of genetic counseling

Gore RH, Bridges JFP, Cohen JS, Biesecker BB.
PMID: 31553105
J Genet Couns. 2019 Dec;28(6):1189-1197. doi: 10.1002/jgc4.1171. Epub 2019 Sep 25.

As exome sequencing expands as a diagnostic tool, patients and providers have voiced concerns about communicating the breadth and scope of potential results when obtaining informed consent. This study aimed to understand how genetic counselors prioritize essential components of...

Total volume of physical activity: TAC, TLAC or TAC(λ).

Preventive medicine

Varma VR, Dey D, Leroux A, Di J, Urbanek J, Xiao L, Zipunnikov V.
PMID: 29080825
Prev Med. 2018 Jan;106:233-235. doi: 10.1016/j.ypmed.2017.10.028. Epub 2017 Nov 11.

No abstract available.

The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex.

Oncoimmunology

Jochems C, Tritsch SR, Knudson KM, Gameiro SR, Smalley Rumfield C, Pellom ST, Morillon YM, Newman R, Marcus W, Szeto C, Rabizadeh S, Wong HC, Soon-Shiong P, Schlom J.
PMID: 30713787
Oncoimmunology. 2018 Nov 27;8(2):e1532764. doi: 10.1080/2162402X.2018.1532764. eCollection 2019.

Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain of IgG1 (N-803, formerly designated as ALT-803) fused to two single chain anti-PD-L1 domains. The fully human IgG1 portion...

Showing 37 to 48 of 1480 entries