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PI3K in T Cell Adhesion and Trafficking.

Frontiers in immunology

Johansen KH, Golec DP, Thomsen JH, Schwartzberg PL, Okkenhaug K.
PMID: 34421914
Front Immunol. 2021 Aug 06;12:708908. doi: 10.3389/fimmu.2021.708908. eCollection 2021.

PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K...

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Johansen KH, Golec DP, Thomsen JH, et al. PI3K in T Cell Adhesion and Trafficking. Front Immunol. 2021;12:708908doi: 10.3389/fimmu.2021.708908.
Johansen, K. H., Golec, D. P., Thomsen, J. H., Schwartzberg, P. L., & Okkenhaug, K. (2021). PI3K in T Cell Adhesion and Trafficking. Frontiers in immunology, 12708908. https://doi.org/10.3389/fimmu.2021.708908
Johansen, Kristoffer H, et al. "PI3K in T Cell Adhesion and Trafficking." Frontiers in immunology vol. 12 (2021): 708908. doi: https://doi.org/10.3389/fimmu.2021.708908
Johansen KH, Golec DP, Thomsen JH, Schwartzberg PL, Okkenhaug K. PI3K in T Cell Adhesion and Trafficking. Front Immunol. 2021 Aug 06;12:708908. doi: 10.3389/fimmu.2021.708908. eCollection 2021. PMID: 34421914; PMCID: PMC8377255.
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mRNA Transport and Local Translation in Glia.

Trends in cell biology

Meservey LM, Topkar VV, Fu MM.
PMID: 33840591
Trends Cell Biol. 2021 Jun;31(6):419-423. doi: 10.1016/j.tcb.2021.03.006. Epub 2021 Apr 08.

Though mRNA transport and local translation are extensively studied in neurons, emerging evidence supports that these cellular processes are also abundant in non-neuronal glial cells. Here, we explore mechanisms of mRNA transport and local translation in oligodendrocytes, astrocytes, microglia,...

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Meservey LM, Topkar VV, Fu MM. mRNA Transport and Local Translation in Glia. Trends Cell Biol. 2021;31(6):419-423doi: 10.1016/j.tcb.2021.03.006.
Meservey, L. M., Topkar, V. V., & Fu, M. M. (2021). mRNA Transport and Local Translation in Glia. Trends in cell biology, 31(6), 419-423. https://doi.org/10.1016/j.tcb.2021.03.006
Meservey, Lindsey Madsen, et al. "mRNA Transport and Local Translation in Glia." Trends in cell biology vol. 31,6 (2021): 419-423. doi: https://doi.org/10.1016/j.tcb.2021.03.006
Meservey LM, Topkar VV, Fu MM. mRNA Transport and Local Translation in Glia. Trends Cell Biol. 2021 Jun;31(6):419-423. doi: 10.1016/j.tcb.2021.03.006. Epub 2021 Apr 08. PMID: 33840591; PMCID: PMC8328280.
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Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases.

The Journal of pharmacology and experimental therapeutics

Goldstein DS, Castillo G, Sullivan P, Sharabi Y.
PMID: 34503991
J Pharmacol Exp Ther. 2021 Nov;379(3):253-259. doi: 10.1124/jpet.121.000826. Epub 2021 Sep 09.

The endogenous catecholamines dopamine (DA), norepinephrine (NE), and epinephrine (EPI) play key roles in neurobehavioral, cardiovascular, and metabolic processes; various clinical disorders; and effects of numerous drugs. Steps in intracellular catecholamine synthesis and metabolism were delineated long ago, but...

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Goldstein DS, Castillo G, Sullivan P, et al. Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases. J Pharmacol Exp Ther. 2021;379(3):253-259doi: 10.1124/jpet.121.000826.
Goldstein, D. S., Castillo, G., Sullivan, P., & Sharabi, Y. (2021). Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases. The Journal of pharmacology and experimental therapeutics, 379(3), 253-259. https://doi.org/10.1124/jpet.121.000826
Goldstein, David S, et al. "Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases." The Journal of pharmacology and experimental therapeutics vol. 379,3 (2021): 253-259. doi: https://doi.org/10.1124/jpet.121.000826
Goldstein DS, Castillo G, Sullivan P, Sharabi Y. Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases. J Pharmacol Exp Ther. 2021 Nov;379(3):253-259. doi: 10.1124/jpet.121.000826. Epub 2021 Sep 09. PMID: 34503991.
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Compound heterozygous .

Journal of neurogenetics

Burke EA, Sturgeon M, Zastrow DB, Fernandez L, Prybol C, Marwaha S, Frothingham EP, Ward PA, Eng CM, Fresard L, Montgomery SB, Enns GM, Fisher PG, Wolfe LA, Harding B, Carrington B, Bishop K, Sood R, Huang Y, Elkahloun A, Toro C, Bassuk AG, Wheeler MT, Markello TC, Gahl WA, Malicdan MCV.
PMID: 33970744
J Neurogenet. 2021 Mar-Jun;35(2):74-83. doi: 10.1080/01677063.2021.1892095. Epub 2021 May 10.

KCTD7 is a member of the potassium channel tetramerization domain-containing protein family and has been associated with progressive myoclonic epilepsy (PME), characterized by myoclonus, epilepsy, and neurological deterioration. Here we report four affected individuals from two unrelated families in...

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Burke EA, Sturgeon M, Zastrow DB, et al. Compound heterozygous . J Neurogenet. 2021;35(2):74-83doi: 10.1080/01677063.2021.1892095.
Burke, E. A., Sturgeon, M., Zastrow, D. B., Fernandez, L., Prybol, C., Marwaha, S., Frothingham, E. P., Ward, P. A., Eng, C. M., Fresard, L., Montgomery, S. B., Enns, G. M., Fisher, P. G., Wolfe, L. A., Harding, B., Carrington, B., Bishop, K., Sood, R., Huang, Y., Elkahloun, A., Toro, C., Bassuk, A. G., Wheeler, M. T., Markello, T. C., Gahl, W. A., & Malicdan, M. C. V. (2021). Compound heterozygous . Journal of neurogenetics, 35(2), 74-83. https://doi.org/10.1080/01677063.2021.1892095
Burke, Elizabeth A, et al. "Compound heterozygous ." Journal of neurogenetics vol. 35,2 (2021): 74-83. doi: https://doi.org/10.1080/01677063.2021.1892095
Burke EA, Sturgeon M, Zastrow DB, Fernandez L, Prybol C, Marwaha S, Frothingham EP, Ward PA, Eng CM, Fresard L, Montgomery SB, Enns GM, Fisher PG, Wolfe LA, Harding B, Carrington B, Bishop K, Sood R, Huang Y, Elkahloun A, Toro C, Bassuk AG, Wheeler MT, Markello TC, Gahl WA, Malicdan MCV. Compound heterozygous . J Neurogenet. 2021 Mar-Jun;35(2):74-83. doi: 10.1080/01677063.2021.1892095. Epub 2021 May 10. PMID: 33970744.
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Making sense of associations between type 2 diabetes, metformin, and breast cancer risk.

British journal of cancer

Park YM, Sandler DP.
PMID: 33911196
Br J Cancer. 2021 Sep;125(7):909-910. doi: 10.1038/s41416-021-01372-3. Epub 2021 Apr 28.

The relationship between type 2 diabetes (T2D), metformin, and breast cancer is complex. T2D may increase risk, but metformin used as first-line treatment of T2D may decrease breast cancer risk. This comment explores efforts to disentangle effects of T2D...

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Park YM, Sandler DP. Making sense of associations between type 2 diabetes, metformin, and breast cancer risk. Br J Cancer. 2021;125(7):909-910doi: 10.1038/s41416-021-01372-3.
Park, Y. M., & Sandler, D. P. (2021). Making sense of associations between type 2 diabetes, metformin, and breast cancer risk. British journal of cancer, 125(7), 909-910. https://doi.org/10.1038/s41416-021-01372-3
Park, Yong-Moon Mark, and Sandler, Dale P. "Making sense of associations between type 2 diabetes, metformin, and breast cancer risk." British journal of cancer vol. 125,7 (2021): 909-910. doi: https://doi.org/10.1038/s41416-021-01372-3
Park YM, Sandler DP. Making sense of associations between type 2 diabetes, metformin, and breast cancer risk. Br J Cancer. 2021 Sep;125(7):909-910. doi: 10.1038/s41416-021-01372-3. Epub 2021 Apr 28. PMID: 33911196; PMCID: PMC8476566.
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Actomyosin dynamics modulate microtubule deformation and growth during T-cell activation.

Molecular biology of the cell

Rey-Suarez I, Rogers N, Kerr S, Shroff H, Upadhyaya A.
PMID: 33826369
Mol Biol Cell. 2021 Aug 19;32(18):1641-1653. doi: 10.1091/mbc.E20-10-0685. Epub 2021 Apr 07.

Activation of T-cells leads to the formation of immune synapses (ISs) with antigen-presenting cells. This requires T-cell polarization and coordination between the actomyosin and microtubule cytoskeletons. The interactions between these two cytoskeletal components during T-cell activation are not well...

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Rey-Suarez I, Rogers N, Kerr S, et al. Actomyosin dynamics modulate microtubule deformation and growth during T-cell activation. Mol Biol Cell. 2021;32(18):1641-1653doi: 10.1091/mbc.E20-10-0685.
Rey-Suarez, I., Rogers, N., Kerr, S., Shroff, H., & Upadhyaya, A. (2021). Actomyosin dynamics modulate microtubule deformation and growth during T-cell activation. Molecular biology of the cell, 32(18), 1641-1653. https://doi.org/10.1091/mbc.E20-10-0685
Rey-Suarez, Ivan, et al. "Actomyosin dynamics modulate microtubule deformation and growth during T-cell activation." Molecular biology of the cell vol. 32,18 (2021): 1641-1653. doi: https://doi.org/10.1091/mbc.E20-10-0685
Rey-Suarez I, Rogers N, Kerr S, Shroff H, Upadhyaya A. Actomyosin dynamics modulate microtubule deformation and growth during T-cell activation. Mol Biol Cell. 2021 Aug 19;32(18):1641-1653. doi: 10.1091/mbc.E20-10-0685. Epub 2021 Apr 07. PMID: 33826369; PMCID: PMC8684730.
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Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain.

Cerebral cortex (New York, N.Y. : 1991)

Murillo A, Navarro AI, Puelles E, Zhang Y, Petros TJ, Pérez-Otaño I.
PMID: 33290502
Cereb Cortex. 2021 Mar 05;31(4):1914-1926. doi: 10.1093/cercor/bhaa330.

GluN3A subunits endow N-Methyl-D-Aspartate receptors (NMDARs) with unique biophysical, trafficking, and signaling properties. GluN3A-NMDARs are typically expressed during postnatal development, when they are thought to gate the refinement of neural circuits by inhibiting synapse maturation, and stabilization. Recent work...

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Murillo A, Navarro AI, Puelles E, et al. Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain. Cereb Cortex. 2021;31(4):1914-1926doi: 10.1093/cercor/bhaa330.
Murillo, A., Navarro, A. I., Puelles, E., Zhang, Y., Petros, T. J., & Pérez-Otaño, I. (2021). Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain. Cerebral cortex (New York, N.Y. : 1991), 31(4), 1914-1926. https://doi.org/10.1093/cercor/bhaa330
Murillo, Alvaro, et al. "Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain." Cerebral cortex (New York, N.Y. : 1991) vol. 31,4 (2021): 1914-1926. doi: https://doi.org/10.1093/cercor/bhaa330
Murillo A, Navarro AI, Puelles E, Zhang Y, Petros TJ, Pérez-Otaño I. Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain. Cereb Cortex. 2021 Mar 05;31(4):1914-1926. doi: 10.1093/cercor/bhaa330. PMID: 33290502; PMCID: PMC7945027.
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Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1.

Cancer research

Mishra AP, Sahu S, Sharan SK.
PMID: 34911781
Cancer Res. 2021 Dec 15;81(24):6080-6082. doi: 10.1158/0008-5472.CAN-21-3480.

The coiled-coil domain of BRCA1 is essential for its interaction with partner and localizer of BRCA2 (PALB2). In mice, loss of this interaction is known to result in Fanconi anemia-associated phenotypes. In a study published in this issue of

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Mishra AP, Sahu S, Sharan SK. Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1. Cancer Res. 2021;81(24):6080-6082doi: 10.1158/0008-5472.CAN-21-3480.
Mishra, A. P., Sahu, S., & Sharan, S. K. (2021). Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1. Cancer research, 81(24), 6080-6082. https://doi.org/10.1158/0008-5472.CAN-21-3480
Mishra, Arun P, et al. "Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1." Cancer research vol. 81,24 (2021): 6080-6082. doi: https://doi.org/10.1158/0008-5472.CAN-21-3480
Mishra AP, Sahu S, Sharan SK. Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1. Cancer Res. 2021 Dec 15;81(24):6080-6082. doi: 10.1158/0008-5472.CAN-21-3480. PMID: 34911781.
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A study of microbial translocation markers in mastocytosis.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Komarow HD, Brenchley JM, Eisch AR, Young ML, Scott LM, Kulinski JM, Heller T, Bai Y, Metcalfe DD.
PMID: 33259149
Clin Exp Allergy. 2021 Feb;51(2):369-372. doi: 10.1111/cea.13798. Epub 2020 Dec 10.

No abstract available.

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Komarow HD, Brenchley JM, Eisch AR, et al. A study of microbial translocation markers in mastocytosis. Clin Exp Allergy. 2020;51(2):369-372doi: 10.1111/cea.13798.
Komarow, H. D., Brenchley, J. M., Eisch, A. R., Young, M. L., Scott, L. M., Kulinski, J. M., Heller, T., Bai, Y., & Metcalfe, D. D. (2021). A study of microbial translocation markers in mastocytosis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 51(2), 369-372. https://doi.org/10.1111/cea.13798
Komarow, Hirsh D, et al. "A study of microbial translocation markers in mastocytosis." Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology vol. 51,2 (2021): 369-372. doi: https://doi.org/10.1111/cea.13798
Komarow HD, Brenchley JM, Eisch AR, Young ML, Scott LM, Kulinski JM, Heller T, Bai Y, Metcalfe DD. A study of microbial translocation markers in mastocytosis. Clin Exp Allergy. 2021 Feb;51(2):369-372. doi: 10.1111/cea.13798. Epub 2020 Dec 10. PMID: 33259149.
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Association Between Serum Iron Biomarkers and Breast Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Von Holle A, O'Brien KM, Sandler DP, Janicek R, Weinberg CR.
PMID: 33293341
Cancer Epidemiol Biomarkers Prev. 2021 Feb;30(2):422-425. doi: 10.1158/1055-9965.EPI-20-0715. Epub 2020 Dec 08.

BACKGROUND: Iron is both essential to life and potentially toxic at higher levels. Epidemiologic studies of iron and breast cancer are sparse, with substantial heterogeneity found in a recent meta-analysis. Evidence based on a comprehensive set of iron biomarkers...

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Von Holle A, O'Brien KM, Sandler DP, et al. Association Between Serum Iron Biomarkers and Breast Cancer. Cancer Epidemiol Biomarkers Prev. 2020;30(2):422-425doi: 10.1158/1055-9965.EPI-20-0715.
Von Holle, A., O'Brien, K. M., Sandler, D. P., Janicek, R., & Weinberg, C. R. (2021). Association Between Serum Iron Biomarkers and Breast Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(2), 422-425. https://doi.org/10.1158/1055-9965.EPI-20-0715
Von Holle, Ann, et al. "Association Between Serum Iron Biomarkers and Breast Cancer." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,2 (2021): 422-425. doi: https://doi.org/10.1158/1055-9965.EPI-20-0715
Von Holle A, O'Brien KM, Sandler DP, Janicek R, Weinberg CR. Association Between Serum Iron Biomarkers and Breast Cancer. Cancer Epidemiol Biomarkers Prev. 2021 Feb;30(2):422-425. doi: 10.1158/1055-9965.EPI-20-0715. Epub 2020 Dec 08. PMID: 33293341; PMCID: PMC7867615.
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The use of teledentistry in facilitating oral health for older adults: A scoping review.

Journal of the American Dental Association (1939)

Ben-Omran MO, Livinski AA, Kopycka-Kedzierawski DT, Boroumand S, Williams D, Weatherspoon DJ, Iafolla TJ, Fontelo P, Dye BA.
PMID: 34521539
J Am Dent Assoc. 2021 Dec;152(12):998-1011.e17. doi: 10.1016/j.adaj.2021.06.005. Epub 2021 Sep 11.

BACKGROUND: Teledentistry is used in many countries to provide oral health care services. However, using teledentistry to provide oral health care services for older adults is not well documented. This knowledge gap needs to be addressed, especially when accessing...

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Ben-Omran MO, Livinski AA, Kopycka-Kedzierawski DT, et al. The use of teledentistry in facilitating oral health for older adults: A scoping review. J Am Dent Assoc. 2021;152(12):998-1011.e17doi: 10.1016/j.adaj.2021.06.005.
Ben-Omran, M. O., Livinski, A. A., Kopycka-Kedzierawski, D. T., Boroumand, S., Williams, D., Weatherspoon, D. J., Iafolla, T. J., Fontelo, P., & Dye, B. A. (2021). The use of teledentistry in facilitating oral health for older adults: A scoping review. Journal of the American Dental Association (1939), 152(12), 998-1011.e17. https://doi.org/10.1016/j.adaj.2021.06.005
Ben-Omran, Munder O, et al. "The use of teledentistry in facilitating oral health for older adults: A scoping review." Journal of the American Dental Association (1939) vol. 152,12 (2021): 998-1011.e17. doi: https://doi.org/10.1016/j.adaj.2021.06.005
Ben-Omran MO, Livinski AA, Kopycka-Kedzierawski DT, Boroumand S, Williams D, Weatherspoon DJ, Iafolla TJ, Fontelo P, Dye BA. The use of teledentistry in facilitating oral health for older adults: A scoping review. J Am Dent Assoc. 2021 Dec;152(12):998-1011.e17. doi: 10.1016/j.adaj.2021.06.005. Epub 2021 Sep 11. PMID: 34521539; PMCID: PMC8627480.
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GCgx: transcriptome-wide exploration of the response to glucocorticoids.

Journal of molecular endocrinology

Cao Q, Boo Irizarry Y, Yazhuk S, Tran T, Gadkari M, Franco LM.
PMID: 34787097
J Mol Endocrinol. 2021 Dec 10;68(2):B1-B4. doi: 10.1530/JME-21-0107.

Glucocorticoids are the cornerstone of immunosuppressive and anti-inflammatory therapy in humans, yet the mechanisms of glucocorticoid immunoregulation and toxicity remain unclear. The response to glucocorticoids is highly cell type-dependent, so translating results from different experimental systems into a better...

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Cao Q, Boo Irizarry Y, Yazhuk S, et al. GCgx: transcriptome-wide exploration of the response to glucocorticoids. J Mol Endocrinol. 2021;68(2):B1-B4doi: 10.1530/JME-21-0107.
Cao, Q., Boo Irizarry, Y., Yazhuk, S., Tran, T., Gadkari, M., & Franco, L. M. (2021). GCgx: transcriptome-wide exploration of the response to glucocorticoids. Journal of molecular endocrinology, 68(2), B1-B4. https://doi.org/10.1530/JME-21-0107
Cao, Qilin, et al. "GCgx: transcriptome-wide exploration of the response to glucocorticoids." Journal of molecular endocrinology vol. 68,2 (2021): B1-B4. doi: https://doi.org/10.1530/JME-21-0107
Cao Q, Boo Irizarry Y, Yazhuk S, Tran T, Gadkari M, Franco LM. GCgx: transcriptome-wide exploration of the response to glucocorticoids. J Mol Endocrinol. 2021 Dec 10;68(2):B1-B4. doi: 10.1530/JME-21-0107. PMID: 34787097.
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Showing 1453 to 1464 of 1480 entries