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Showing 25 to 36 of 78 entries
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Novel strategies using modern radiotherapy to improve pancreatic cancer outcomes: toward a new standard?.

Therapeutic advances in medical oncology

Bouchart C, Navez J, Closset J, Hendlisz A, Van Gestel D, Moretti L, Van Laethem JL.
PMID: 32684987
Ther Adv Med Oncol. 2020 Jul 07;12:1758835920936093. doi: 10.1177/1758835920936093. eCollection 2020.

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive solid tumours with an estimated 5-year overall survival rate of 7% for all stages combined. In this highly resistant disease that is located in the vicinity of many radiosensitive...

A prospective study on the prevalence and risk factors of poststroke depression.

Cerebrovascular diseases extra

De Ryck A, Brouns R, Fransen E, Geurden M, Van Gestel G, Wilssens I, De Ceulaer L, Mariën P, De Deyn PP, Engelborghs S.
PMID: 23626594
Cerebrovasc Dis Extra. 2013 Jan 26;3(1):1-13. doi: 10.1159/000345557. Print 2013 Jan.

BACKGROUND AND PURPOSE: Poststroke depression (PSD) is common. Early detection of depressive symptoms and identification of patients at risk for PSD are important as PSD negatively affects stroke outcome and costs of medical care. Therefore, the aim of this...

Amplification of chirality in benzene tricarboxamide helical supramolecular polymers.

Chemical communications (Cambridge, England)

Wilson AJ, van Gestel J, Sijbesma RP, Meijer EW.
PMID: 17057858
Chem Commun (Camb). 2006 Nov 13;(42):4404-6. doi: 10.1039/b610051a. Epub 2006 Sep 13.

The chirality of benzene tricarboxamides is expressed and amplified into the helicity of self-assembled columnar aggregates according to 'sergeants and soldiers' and 'majority rules' principles; the strength of the amplification is analysed quantitatively and the effect of the number...

Impact of steric interactions on the helical transition in assemblies of discotic molecules.

Langmuir : the ACS journal of surfaces and colloids

van Gestel J, van der Schoot P.
PMID: 16378458
Langmuir. 2006 Jan 03;22(1):446-52. doi: 10.1021/la0521903.

We investigate theoretically the effect of excluded-volume interactions on the helical configurational transition of supramolecular assemblies in solutions of chiral disklike molecules. To this end, we set up a second-virial theory within the context of the helical self-assembly of...

Financial time series prediction using least squares support vector machines within the evidence framework.

IEEE transactions on neural networks

Van Gestel T, Suykens JK, Baestaens DE, Lambrechts A, Lanckriet G, Vandaele B, De Moor B, Vandewalle J.
PMID: 18249915
IEEE Trans Neural Netw. 2001;12(4):809-21. doi: 10.1109/72.935093.

The Bayesian evidence framework is applied in this paper to least squares support vector machine (LS-SVM) regression in order to infer nonlinear models for predicting a financial time series and the related volatility. On the first level of inference,...

Incorporation of the biomarker concept in ecotoxicology calls for a redefinition of terms.

Ecotoxicology (London, England)

Van Gestel CA, Van Brummelen TC.
PMID: 24193812
Ecotoxicology. 1996 Aug;5(4):217-25. doi: 10.1007/BF00118992.

: Biomarkers have received a lot of attention but the biomarker concept has not yet been defined properly. As a consequence, various interpretations of the term 'biomarker' exist, some of which overlap with well-established ecotoxicological concepts. To allow incorporation...

Measurement of the Neutron Lifetime by Counting Trapped Protons.

Journal of research of the National Institute of Standards and Technology

Wietfeldt FE, Dewey MS, Gilliam DM, Nico JS, Fei X, Snow WM, Greene GL, Pauwels J, Eykens R, Lamberty A, Van Gestel J.
PMID: 27308145
J Res Natl Inst Stand Technol. 2005 Aug 01;110(4):327-31. doi: 10.6028/jres.110.048. Print 2005.

We measured the neutron decay lifetime by counting in-beam neutron decay recoil protons trapped in a quasi-Penning trap. The absolute neutron beam fluence was measured by capture in a thin (6)LiF foil detector with known efficiency. The combination of...

Oligometastatic Disease Detection with .

Cancers

Artigas C, Diamand R, Shagera QA, Plouznikoff N, Fokoue F, Otte FX, Gil T, Peltier A, Van Gestel D, Flamen P.
PMID: 34638466
Cancers (Basel). 2021 Oct 04;13(19). doi: 10.3390/cancers13194982.

Metastasis-directed therapy (MDT) in oligometastatic prostate cancer has the potential of delaying the start of androgen deprivation therapy (ADT) and disease progression. We aimed to analyze the efficacy of PSMA-PET/CT in detecting oligometastatic disease (OMD), to look for predictive...

Aging-related modifications to G protein-coupled receptor signaling diversity.

Pharmacology & therapeutics

van Gastel J, Leysen H, Boddaert J, Vangenechten L, Luttrell LM, Martin B, Maudsley S.
PMID: 33316288
Pharmacol Ther. 2021 Jul;223:107793. doi: 10.1016/j.pharmthera.2020.107793. Epub 2020 Dec 13.

Aging is a highly complex molecular process, affecting nearly all tissue systems in humans and is the highest risk factor in developing neurodegenerative disorders such as Alzheimer's and Parkinson's disease, cardiovascular disease and Type 2 diabetes mellitus. The intense...

Who accepts nudges? nudge acceptability from a self-regulation perspective.

PloS one

van Gestel LC, Adriaanse MA, de Ridder DTD.
PMID: 34860843
PLoS One. 2021 Dec 03;16(12):e0260531. doi: 10.1371/journal.pone.0260531. eCollection 2021.

BACKGROUND: Public acceptability of nudging is receiving increasingly more attention, but studies remain limited to evaluations of aspects of the nudge itself or (inferred intentions) of the nudger. Yet, it is important to investigate which individuals are likely to...

Humanized Mice as a Valuable Pre-Clinical Model for Cancer Immunotherapy Research.

Frontiers in oncology

Cogels MM, Rouas R, Ghanem GE, Martinive P, Awada A, Van Gestel D, Krayem M.
PMID: 34869042
Front Oncol. 2021 Nov 18;11:784947. doi: 10.3389/fonc.2021.784947. eCollection 2021.

Immunotherapy with checkpoint inhibitors opened new horizons in cancer treatment. Clinical trials for novel immunotherapies or unexplored combination regimens either need years of development or are simply impossible to perform like is the case in cancer patients with limited...

Advanced cutaneous squamous cell carcinoma of the head in two renal transplanted patients treated with cemiplimab.

Journal of the European Academy of Dermatology and Venereology : JEADV

Orte Cano C, Van Meerhaeghe T, Tannous J, Lienard D, Van Gestel D, Cuylits N, Luce S, Carlot S, Le Moine A, Aspeslagh S, Del Marmol V.
PMID: 34855244
J Eur Acad Dermatol Venereol. 2022 Jan;36:53-58. doi: 10.1111/jdv.17658.

It is well known that organ transplant recipients are prone to develop non-melanoma skin cancers, particularly cutaneous squamous cell carcinoma (cSCC). This is explained by the long-term use of immunosuppressants and thus the decrease of the immunosurveillance that protects...

Showing 25 to 36 of 78 entries