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1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs.

The Science of the total environment

Godri Pollitt KJ, Kim JH, Peccia J, Elimelech M, Zhang Y, Charkoftaki G, Hodges B, Zucker I, Huang H, Deziel NC, Murphy K, Ishii M, Johnson CH, Boissevain A, O'Keefe E, Anastas PT, Orlicky D, Thompson DC, Vasiliou V.
PMID: 31302550
Sci Total Environ. 2019 Nov 10;690:853-866. doi: 10.1016/j.scitotenv.2019.06.443. Epub 2019 Jun 28.

1,4-Dioxane has historically been used to stabilize chlorinated solvents and more recently has been found as a contaminant of numerous consumer and food products. Once discharged into the environment, its physical and chemical characteristics facilitate migration in groundwater, resulting...

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Godri Pollitt KJ, Kim JH, Peccia J, et al. 1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs. Sci Total Environ. 2019;690:853-866doi: 10.1016/j.scitotenv.2019.06.443.
Godri Pollitt, K. J., Kim, J. H., Peccia, J., Elimelech, M., Zhang, Y., Charkoftaki, G., Hodges, B., Zucker, I., Huang, H., Deziel, N. C., Murphy, K., Ishii, M., Johnson, C. H., Boissevain, A., O'Keefe, E., Anastas, P. T., Orlicky, D., Thompson, D. C., & Vasiliou, V. (2019). 1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs. The Science of the total environment, 690853-866. https://doi.org/10.1016/j.scitotenv.2019.06.443
Godri Pollitt, Krystal J, et al. "1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs." The Science of the total environment vol. 690 (2019): 853-866. doi: https://doi.org/10.1016/j.scitotenv.2019.06.443
Godri Pollitt KJ, Kim JH, Peccia J, Elimelech M, Zhang Y, Charkoftaki G, Hodges B, Zucker I, Huang H, Deziel NC, Murphy K, Ishii M, Johnson CH, Boissevain A, O'Keefe E, Anastas PT, Orlicky D, Thompson DC, Vasiliou V. 1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs. Sci Total Environ. 2019 Nov 10;690:853-866. doi: 10.1016/j.scitotenv.2019.06.443. Epub 2019 Jun 28. PMID: 31302550.
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Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork.

Journal of biological rhythms

Riggle JP, Onishi KG, Love JA, Beach DE, Zucker I, Prendergast BJ.
PMID: 34931572
J Biol Rhythms. 2021 Dec 21;7487304211060896. doi: 10.1177/07487304211060896. Epub 2021 Dec 21.

Circadian rhythms are generated by interlocked transcriptional-translational feedback loops of circadian clock genes and their protein products. Mice homozygous for a functional deletion in the Period-2 gene (

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Riggle JP, Onishi KG, Love JA, et al. Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork. J Biol Rhythms. 2021;7487304211060896doi: 10.1177/07487304211060896.
Riggle, J. P., Onishi, K. G., Love, J. A., Beach, D. E., Zucker, I., & Prendergast, B. J. (2021). Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork. Journal of biological rhythms, 7487304211060896. https://doi.org/10.1177/07487304211060896
Riggle, Jonathan P, et al. "Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork." Journal of biological rhythms vol. (2021): 7487304211060896. doi: https://doi.org/10.1177/07487304211060896
Riggle JP, Onishi KG, Love JA, Beach DE, Zucker I, Prendergast BJ. Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork. J Biol Rhythms. 2021 Dec 21;7487304211060896. doi: 10.1177/07487304211060896. Epub 2021 Dec 21. PMID: 34931572.
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Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication.

Exercise and sport sciences reviews

Gao L, Wang HJ, Tian C, Zucker IH.
PMID: 33927165
Exerc Sport Sci Rev. 2021 Jul 01;49(3):213-222. doi: 10.1249/JES.0000000000000257.

This review explores the hypothesis that the repetitive contraction-relaxation that occurs during chronic exercise activates skeletal myocyte nuclear factor erythroid-derived 2-like 2 (Nrf2) to upregulate antioxidant enzymes. These proteins are secreted into the circulation within extracellular vesicles and taken...

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Gao L, Wang HJ, Tian C, et al. Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication. Exerc Sport Sci Rev. 2021;49(3):213-222doi: 10.1249/JES.0000000000000257.
Gao, L., Wang, H. J., Tian, C., & Zucker, I. H. (2021). Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication. Exercise and sport sciences reviews, 49(3), 213-222. https://doi.org/10.1249/JES.0000000000000257
Gao, Lie, et al. "Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication." Exercise and sport sciences reviews vol. 49,3 (2021): 213-222. doi: https://doi.org/10.1249/JES.0000000000000257
Gao L, Wang HJ, Tian C, Zucker IH. Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication. Exerc Sport Sci Rev. 2021 Jul 01;49(3):213-222. doi: 10.1249/JES.0000000000000257. PMID: 33927165; PMCID: PMC8195856.
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Q-Finder: An Algorithm for Credible Subgroup Discovery in Clinical Data Analysis - An Application to the International Diabetes Management Practice Study.

Frontiers in artificial intelligence

Esnault C, Gadonna ML, Queyrel M, Templier A, Zucker JD.
PMID: 33733209
Front Artif Intell. 2020 Dec 17;3:559927. doi: 10.3389/frai.2020.559927. eCollection 2020.

Addressing the heterogeneity of both the outcome of a disease and the treatment response to an intervention is a mandatory pathway for regulatory approval of medicines. In randomized clinical trials (RCTs), confirmatory subgroup analyses focus on the assessment of...

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Esnault C, Gadonna ML, Queyrel M, et al. Q-Finder: An Algorithm for Credible Subgroup Discovery in Clinical Data Analysis - An Application to the International Diabetes Management Practice Study. Front Artif Intell. 2020;3:559927doi: 10.3389/frai.2020.559927.
Esnault, C., Gadonna, M. L., Queyrel, M., Templier, A., & Zucker, J. D. (2020). Q-Finder: An Algorithm for Credible Subgroup Discovery in Clinical Data Analysis - An Application to the International Diabetes Management Practice Study. Frontiers in artificial intelligence, 3559927. https://doi.org/10.3389/frai.2020.559927
Esnault, Cyril, et al. "Q-Finder: An Algorithm for Credible Subgroup Discovery in Clinical Data Analysis - An Application to the International Diabetes Management Practice Study." Frontiers in artificial intelligence vol. 3 (2020): 559927. doi: https://doi.org/10.3389/frai.2020.559927
Esnault C, Gadonna ML, Queyrel M, Templier A, Zucker JD. Q-Finder: An Algorithm for Credible Subgroup Discovery in Clinical Data Analysis - An Application to the International Diabetes Management Practice Study. Front Artif Intell. 2020 Dec 17;3:559927. doi: 10.3389/frai.2020.559927. eCollection 2020. PMID: 33733209; PMCID: PMC7861304.
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Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement.

International journal of impotence research

Zucker IJ, Masterson TA.
PMID: 34663926
Int J Impot Res. 2021 Oct 18; doi: 10.1038/s41443-021-00477-w. Epub 2021 Oct 18.

Low testosterone affects an increasing number of patients each year resulting in a steady increase in prescriptions for testosterone replacement therapy (TRT). In 2018, the American Urological Association (AUA) and the Endocrine Society (ES) published their guidelines for treating...

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Zucker IJ, Masterson TA. Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement. Int J Impot Res. 2021;doi: 10.1038/s41443-021-00477-w.
Zucker, I. J., & Masterson, T. A. (2021). Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement. International journal of impotence research, . https://doi.org/10.1038/s41443-021-00477-w
Zucker, Isaac Jake, and Masterson, Thomas A. "Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement." International journal of impotence research vol. (2021). doi: https://doi.org/10.1038/s41443-021-00477-w
Zucker IJ, Masterson TA. Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement. Int J Impot Res. 2021 Oct 18; doi: 10.1038/s41443-021-00477-w. Epub 2021 Oct 18. PMID: 34663926.
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Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters.

Journal of biological rhythms

Piekarski DJ, Jarjisian SG, Perez L, Ahmad H, Dhawan N, Zucker I, Kriegsfeld LJ.
PMID: 24916391
J Biol Rhythms. 2014 Jun;29(3):181-191. doi: 10.1177/0748730414532423. Epub 2014 Jun 10.

Long days (LDs) stimulate and short days (SDs) inhibit reproduction in photoperiodic rodents by modifying nocturnal pineal melatonin secretion. In LD Turkish hamsters, unlike other rodents, pinealectomy induces reproductive quiescence comparable to that produced by SDs. We assessed whether...

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Piekarski DJ, Jarjisian SG, Perez L, et al. Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters. J Biol Rhythms. 2014;29(3):181-191doi: 10.1177/0748730414532423.
Piekarski, D. J., Jarjisian, S. G., Perez, L., Ahmad, H., Dhawan, N., Zucker, I., & Kriegsfeld, L. J. (2014). Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters. Journal of biological rhythms, 29(3), 181-191. https://doi.org/10.1177/0748730414532423
Piekarski, David J, et al. "Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters." Journal of biological rhythms vol. 29,3 (2014): 181-191. doi: https://doi.org/10.1177/0748730414532423
Piekarski DJ, Jarjisian SG, Perez L, Ahmad H, Dhawan N, Zucker I, Kriegsfeld LJ. Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters. J Biol Rhythms. 2014 Jun;29(3):181-191. doi: 10.1177/0748730414532423. Epub 2014 Jun 10. PMID: 24916391; PMCID: PMC4387122.
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Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity.

Chemosphere

Rubin AE, Zucker I.
PMID: 34890605
Chemosphere. 2021 Dec 07;289:133212. doi: 10.1016/j.chemosphere.2021.133212. Epub 2021 Dec 07.

High levels of persistent contaminants such as microplastics (MPs) and trace organic compounds (TrOCs) in the aquatic environment have become a major threat on the ecosystem and human health. While MP's role as a vector of environmental TrOCs is...

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Rubin AE, Zucker I. Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity. Chemosphere. 2021;289:133212doi: 10.1016/j.chemosphere.2021.133212.
Rubin, A. E., & Zucker, I. (2021). Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity. Chemosphere, 289133212. https://doi.org/10.1016/j.chemosphere.2021.133212
Rubin, Andrey Ethan, and Zucker, Ines. "Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity." Chemosphere vol. 289 (2021): 133212. doi: https://doi.org/10.1016/j.chemosphere.2021.133212
Rubin AE, Zucker I. Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity. Chemosphere. 2021 Dec 07;289:133212. doi: 10.1016/j.chemosphere.2021.133212. Epub 2021 Dec 07. PMID: 34890605.
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Asthma in Youth and Early-onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents.

The Journal of clinical endocrinology and metabolism

Shapiro M, Arbel C, Zucker I, Balmor GR, Lutski M, Derazne E, Beer Z, Pinhas-Hamiel O, Mosenzon O, Tzur D, Afek A, Tirosh A, Cukierman-Yaffe T, Gerstein HC, Rosenberg V, Chodick G, Raz I, Twig G.
PMID: 34291806
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5043-e5053. doi: 10.1210/clinem/dgab542.

BACKGROUND: The prevalence of both asthma and early-onset diabetes is on the rise; however, the association between them remains unclear. We examined a possible association of asthma at adolescence with type 2 diabetes in young adulthood.METHODS: This is a...

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Shapiro M, Arbel C, Zucker I, et al. Asthma in Youth and Early-onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents. J Clin Endocrinol Metab. 2021;106(12):e5043-e5053doi: 10.1210/clinem/dgab542.
Shapiro, M., Arbel, C., Zucker, I., Balmor, G. R., Lutski, M., Derazne, E., Beer, Z., Pinhas-Hamiel, O., Mosenzon, O., Tzur, D., Afek, A., Tirosh, A., Cukierman-Yaffe, T., Gerstein, H. C., Rosenberg, V., Chodick, G., Raz, I., & Twig, G. (2021). Asthma in Youth and Early-onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents. The Journal of clinical endocrinology and metabolism, 106(12), e5043-e5053. https://doi.org/10.1210/clinem/dgab542
Shapiro, Michael, et al. "Asthma in Youth and Early-onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents." The Journal of clinical endocrinology and metabolism vol. 106,12 (2021): e5043-e5053. doi: https://doi.org/10.1210/clinem/dgab542
Shapiro M, Arbel C, Zucker I, Balmor GR, Lutski M, Derazne E, Beer Z, Pinhas-Hamiel O, Mosenzon O, Tzur D, Afek A, Tirosh A, Cukierman-Yaffe T, Gerstein HC, Rosenberg V, Chodick G, Raz I, Twig G. Asthma in Youth and Early-onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents. J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5043-e5053. doi: 10.1210/clinem/dgab542. PMID: 34291806.
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Recent developments in the redox-switched binding of organic compounds.

Chemical Society reviews

Tucker JH, Collinson SR.
PMID: 12122640
Chem Soc Rev. 2002 May;31(3):147-56. doi: 10.1039/a804251i.

This review summarizes and puts into context recent advances in the field of redox-switched binding processes, with particular reference to the interaction between redox-active compounds and organic compounds, both charged and neutral. Simple homogeneous, two-component systems are discussed at...

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Tucker JH, Collinson SR. Recent developments in the redox-switched binding of organic compounds. Chem Soc Rev. 2002;31(3):147-56doi: 10.1039/a804251i.
Tucker, J. H., & Collinson, S. R. (2002). Recent developments in the redox-switched binding of organic compounds. Chemical Society reviews, 31(3), 147-56. https://doi.org/10.1039/a804251i
Tucker, James H R, and Collinson, Simon R. "Recent developments in the redox-switched binding of organic compounds." Chemical Society reviews vol. 31,3 (2002): 147-56. doi: https://doi.org/10.1039/a804251i
Tucker JH, Collinson SR. Recent developments in the redox-switched binding of organic compounds. Chem Soc Rev. 2002 May;31(3):147-56. doi: 10.1039/a804251i. PMID: 12122640.
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Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in .

Frontiers in physiology

Moore TM, Lin AJ, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Nguyen CQ, Yackly A, Mahata SK, Wanagat J, Stiles L, Turcotte LP, Crosbie RH, Zhou Z.
PMID: 32636760
Front Physiol. 2020 Jun 19;11:690. doi: 10.3389/fphys.2020.00690. eCollection 2020.

Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the...

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Moore TM, Lin AJ, Strumwasser AR, et al. Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in . Front Physiol. 2020;11:690doi: 10.3389/fphys.2020.00690.
Moore, T. M., Lin, A. J., Strumwasser, A. R., Cory, K., Whitney, K., Ho, T., Ho, T., Lee, J. L., Rucker, D. H., Nguyen, C. Q., Yackly, A., Mahata, S. K., Wanagat, J., Stiles, L., Turcotte, L. P., Crosbie, R. H., & Zhou, Z. (2020). Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in . Frontiers in physiology, 11690. https://doi.org/10.3389/fphys.2020.00690
Moore, Timothy M, et al. "Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in ." Frontiers in physiology vol. 11 (2020): 690. doi: https://doi.org/10.3389/fphys.2020.00690
Moore TM, Lin AJ, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Nguyen CQ, Yackly A, Mahata SK, Wanagat J, Stiles L, Turcotte LP, Crosbie RH, Zhou Z. Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in . Front Physiol. 2020 Jun 19;11:690. doi: 10.3389/fphys.2020.00690. eCollection 2020. PMID: 32636760; PMCID: PMC7317021.
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Temperature Resistant Binary SLES/Nonionic Surfactant Mixtures at the Air/Water Interface.

Langmuir : the ACS journal of surfaces and colloids

Smith C, Lu JR, Tucker IM, Grainger D, Li P, Webster JRP, Thomas RK.
PMID: 30010345
Langmuir. 2018 Aug 14;34(32):9442-9452. doi: 10.1021/acs.langmuir.8b01093. Epub 2018 Jul 30.

Surface compositions of adsorbed monolayers at the air/water interface, formed from binary surfactant mixtures in equilibrium, have been studied using neutron reflectivity at three discrete temperatures: 10, 25, and 40 °C. The binary compositions studied are sodium lauryl dodecyl...

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Smith C, Lu JR, Tucker IM, et al. Temperature Resistant Binary SLES/Nonionic Surfactant Mixtures at the Air/Water Interface. Langmuir. 2018;34(32):9442-9452doi: 10.1021/acs.langmuir.8b01093.
Smith, C., Lu, J. R., Tucker, I. M., Grainger, D., Li, P., Webster, J. R. P., & Thomas, R. K. (2018). Temperature Resistant Binary SLES/Nonionic Surfactant Mixtures at the Air/Water Interface. Langmuir : the ACS journal of surfaces and colloids, 34(32), 9442-9452. https://doi.org/10.1021/acs.langmuir.8b01093
Smith, Charles, et al. "Temperature Resistant Binary SLES/Nonionic Surfactant Mixtures at the Air/Water Interface." Langmuir : the ACS journal of surfaces and colloids vol. 34,32 (2018): 9442-9452. doi: https://doi.org/10.1021/acs.langmuir.8b01093
Smith C, Lu JR, Tucker IM, Grainger D, Li P, Webster JRP, Thomas RK. Temperature Resistant Binary SLES/Nonionic Surfactant Mixtures at the Air/Water Interface. Langmuir. 2018 Aug 14;34(32):9442-9452. doi: 10.1021/acs.langmuir.8b01093. Epub 2018 Jul 30. PMID: 30010345.
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Mixing Natural and Synthetic Surfactants: Co-Adsorption of Triterpenoid Saponins and Sodium Dodecyl Sulfate at the Air-Water Interface.

Langmuir : the ACS journal of surfaces and colloids

Tucker IM, Burley A, Petkova RE, Hosking SL, Penfold J, Thomas RK, Li PX, Webster JRP, Welbourn R.
PMID: 32388992
Langmuir. 2020 Jun 02;36(21):5997-6006. doi: 10.1021/acs.langmuir.0c00922. Epub 2020 May 18.

Saponins are highly surface active glycosides, derived from a wide range of plant species. Their ability to produce stable foams and emulsions has stimulated their applications in beverages, foods, and cosmetics. To explore a wider range of potential applications,...

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Tucker IM, Burley A, Petkova RE, et al. Mixing Natural and Synthetic Surfactants: Co-Adsorption of Triterpenoid Saponins and Sodium Dodecyl Sulfate at the Air-Water Interface. Langmuir. 2020;36(21):5997-6006doi: 10.1021/acs.langmuir.0c00922.
Tucker, I. M., Burley, A., Petkova, R. E., Hosking, S. L., Penfold, J., Thomas, R. K., Li, P. X., Webster, J. R. P., & Welbourn, R. (2020). Mixing Natural and Synthetic Surfactants: Co-Adsorption of Triterpenoid Saponins and Sodium Dodecyl Sulfate at the Air-Water Interface. Langmuir : the ACS journal of surfaces and colloids, 36(21), 5997-6006. https://doi.org/10.1021/acs.langmuir.0c00922
Tucker, I M, et al. "Mixing Natural and Synthetic Surfactants: Co-Adsorption of Triterpenoid Saponins and Sodium Dodecyl Sulfate at the Air-Water Interface." Langmuir : the ACS journal of surfaces and colloids vol. 36,21 (2020): 5997-6006. doi: https://doi.org/10.1021/acs.langmuir.0c00922
Tucker IM, Burley A, Petkova RE, Hosking SL, Penfold J, Thomas RK, Li PX, Webster JRP, Welbourn R. Mixing Natural and Synthetic Surfactants: Co-Adsorption of Triterpenoid Saponins and Sodium Dodecyl Sulfate at the Air-Water Interface. Langmuir. 2020 Jun 02;36(21):5997-6006. doi: 10.1021/acs.langmuir.0c00922. Epub 2020 May 18. PMID: 32388992.
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