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Showing 25 to 36 of 386 entries
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Gene variants of osteoprotegerin, estrogen-, calcitonin- and vitamin D-receptor genes and serum markers of bone metabolism in patients with Gaucher disease type 1.

Therapeutics and clinical risk management

Zimmermann A, Popp RA, Rossmann H, Bucerzan S, Nascu I, Leucuta D, Weber MM, Grigorescu-Sido P.
PMID: 30498352
Ther Clin Risk Manag. 2018 Oct 24;14:2069-2080. doi: 10.2147/TCRM.S177480. eCollection 2018.

PURPOSE: Osteopathy/osteoporosis in Gaucher disease type 1 (GD1) shows variable responses to enzyme replacement therapy (ERT); the pathogenesis is incompletely understood. We aimed to investigate the effects of several gene variants on bone mineral density (BMD) and serum markers...

Catalytic hydrogenation of α,β-unsaturated carboxylic acid derivatives using copper(i)/N-heterocyclic carbene complexes.

Chemical communications (Cambridge, England)

Zimmermann BM, Kobosil SCK, Teichert JF.
PMID: 30714586
Chem Commun (Camb). 2019 Feb 19;55(16):2293-2296. doi: 10.1039/c8cc09853k.

A simple and air-stable copper(i)/N-heterocyclic carbene complex enables the catalytic hydrogenation of enoates and enamides, hitherto unreactive substrates employing homogeneous copper catalysis and H2 as a terminal reducing agent. This atom economic transformation replaces commonly employed hydrosilanes and can...

DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia.

Frontiers in oncology

Carr MI, Zimmermann A, Chiu LY, Zenke FT, Blaukat A, Vassilev LT.
PMID: 32117773
Front Oncol. 2020 Feb 13;10:127. doi: 10.3389/fonc.2020.00127. eCollection 2020.

Despite significant advances in the treatment of acute myeloid leukemia (AML) the long-term prognosis remains relatively poor and there is an urgent need for improved therapies with increased potency and tumor selectivity. Mylotarg is the first AML-targeting drug from...

Content, evaluations and influences in newspaper coverage of predictive genetic testing: A comparative media content analysis from the United Kingdom and Switzerland.

Public understanding of science (Bristol, England)

Zimmermann BM, Aebi N, Kolb S, Shaw D, Elger BS.
PMID: 30583711
Public Underst Sci. 2019 Apr;28(3):256-274. doi: 10.1177/0963662518816014. Epub 2018 Dec 24.

Predictive genetic testing often entails challenging decisions about preventive measures and uncertain health-related risk predictions. Because of its increasing availability, it is important to assess how to debate it publicly. Newspaper content analysis represents a common and reliable way...

Radiative lifetimes and absolute transition probabilities in Ti II.

Physical review. A, General physics

Kwiatkowski M, Werner K, Zimmermann P.
PMID: 9895807
Phys Rev A Gen Phys. 1985 Apr;31(4):2695-2697. doi: 10.1103/physreva.31.2695.

No abstract available.

Photoionization study of the 3pns and 3pnd 1P1 resonances in Mg I.

Physical review. A, General physics

Fiedler W, Kortenkamp C, Zimmermann P.
PMID: 9898697
Phys Rev A Gen Phys. 1987 Jul 01;36(1):384-385. doi: 10.1103/physreva.36.384.

No abstract available.

Mesoporous Poly(melamine-.

Molecules (Basel, Switzerland)

Borchert KBL, Steinbach C, Reis B, Gerlach N, Zimmermann P, Schwarz S, Schwarz D.
PMID: 34771024
Molecules. 2021 Oct 31;26(21). doi: 10.3390/molecules26216615.

Due to the existence-threatening risk to aquatic life and entire ecosystems, the removal of oxyanions such as sulfate and phosphate from anthropogenic wastewaters, such as municipal effluents and acid mine drainage, is inevitable. Furthermore, phosphorus is an indispensable resource...

File audit to assess sustained fidelity to a recovery and wellbeing oriented mental health service model: an Australian case study.

Archives of public health = Archives belges de sante publique

Jones CL, Deane FP, Wolstencroft K, Zimmermann A.
PMID: 31768253
Arch Public Health. 2019 Nov 23;77:50. doi: 10.1186/s13690-019-0377-6. eCollection 2019.

BACKGROUND: Over the past decade there has been increasing attention to implementing recovery-oriented approaches within mental health service practice and enhancing fidelity to such approaches. However, as is often the case with evidence-based practices, less attention has been paid...

Antibiotic exposure and adverse long-term health outcomes in children: a systematic review and meta-analysis.

The Journal of infection

Duong QA, Pittet LF, Curtis N, Zimmermann P.
PMID: 35021114
J Infect. 2022 Jan 09; doi: 10.1016/j.jinf.2022.01.005. Epub 2022 Jan 09.

BACKGROUND: Antibiotics are among the most commonly used drugs in children. In addition to inducing antibiotic resistance, antibiotic exposure has been associated with long-term adverse health outcomes.METHODS: A systematic search using PRISMA Guidelines to identify original studies reporting associations...

Family risk and early attachment development: The differential role of parental sensitivity.

Infant mental health journal

Gerlach J, Fößel JM, Vierhaus M, Sann A, Eickhorst A, Zimmermann P, Spangler G.
PMID: 35020951
Infant Ment Health J. 2022 Jan 12; doi: 10.1002/imhj.21964. Epub 2022 Jan 12.

Family risks are known to be detrimental to children's attachment development. This study investigated whether parental sensitivity plays different roles in early attachment development in the context of risk: Sensitivity was hypothesized to mediate risk effects on attachment, as...

Influence of measurement and sizing techniques in thoracic endovascular aortic repair on outcome in acute complicated type B aortic dissections.

Interactive cardiovascular and thoracic surgery

Rychla M, Dueppers P, Meuli L, Rancic Z, Menges AL, Kopp R, Zimmermann A, Reutersberg B.
PMID: 34788425
Interact Cardiovasc Thorac Surg. 2021 Nov 11; doi: 10.1093/icvts/ivab300. Epub 2021 Nov 11.

OBJECTIVES: Thoracic endovascular aortic repair (TEVAR) is the first-line therapy in acute complicated type B aortic dissections (cTBAD). Nevertheless, no evidence-based consensus on the optimal measurement technique and sizing for TEVAR in cTBAD exists. The aim was to evaluate...

Spermidine supplementation in rare translation-associated disorders.

Cell stress

Zimmermann A, Carmona-Gutierrez D, Madeo F.
PMID: 33688620
Cell Stress. 2021 Mar 08;5(3):29-32. doi: 10.15698/cst2021.03.243.

The polyamine spermidine is essential for protein translation in eukaryotes, both as a substrate for the hypusination of the translation initiation factor eIF5A as well as general translational fidelity. Dwindling spermidine levels during aging have been implicated in reduced...

Showing 25 to 36 of 386 entries