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Showing 1945 to 1948 of 1948 entries
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Circ_0017639 facilitates proliferative, migratory, and invasive potential of non-small cell lung cancer (NSCLC) cells via PI3K/AKT signaling pathway.

Bioengineered

Zhang HB, Qiu XM, Zhang YC, Huang TT, Zuo ZJ, Zhang T.
PMID: 35000535
Bioengineered. 2022 Jan;13(1):1590-1601. doi: 10.1080/21655979.2021.2020390.

Non-small cell lung cancer (NSCLC) has increased morbidity and mortality rate worldwide. The current NSCLS therapies are associated with poor outcomes and need further improvement. CircRNAs were shown to regulate NSCLC progression. However, little is known re garding the...

Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia.

Blood advances

Leung HHL, Perdomo J, Ahmadi Z, Yan F, McKenzie SE, Chong BH.
PMID: 34478504
Blood Adv. 2021 Dec 14;5(23):5439-5451. doi: 10.1182/bloodadvances.2020003093.

Heparin-induced thrombocytopenia (HIT) is associated with severe and potentially lethal thrombotic complications. NETosis was recently shown to be an important driver of thrombosis in HIT. We investigated the role of reactive oxygen species (ROS) and nicotinamide adenine dinucleotide phosphate...

Panax Notoginseng Saponins Protect H9c2 Cells From Hypoxia-reoxygenation Injury Through the Forkhead Box O3a Hypoxia-inducible Factor-1 Alpha Cell Signaling Pathway.

Journal of cardiovascular pharmacology

Liu XW, Lu MK, Zhong HT, Liu JJ, Fu YP.
PMID: 34354001
J Cardiovasc Pharmacol. 2021 Aug 05;78(5):e681-e689. doi: 10.1097/FJC.0000000000001120.

ABSTRACT: Panax notoginseng saponins (PNS) are commonly used in the treatment of cardiovascular diseases. Whether PNS can protect myocardial ischemia-reperfusion injury by regulating the forkhead box O3a hypoxia-inducible factor-1 alpha (FOXO3a/HIF-1α) cell signaling pathway remains unclear. The purpose of...

Protein domain identification methods and online resources.

Computational and structural biotechnology journal

Wang Y, Zhang H, Zhong H, Xue Z.
PMID: 33680357
Comput Struct Biotechnol J. 2021 Feb 02;19:1145-1153. doi: 10.1016/j.csbj.2021.01.041. eCollection 2021.

Protein domains are the basic units of proteins that can fold, function, and evolve independently. Knowledge of protein domains is critical for protein classification, understanding their biological functions, annotating their evolutionary mechanisms and protein design. Thus, over the past...

Showing 1945 to 1948 of 1948 entries