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Showing 9985 to 9996 of 52260 entries
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Additives improved saprotrophic fungi for formation of humic acids in chicken manure and corn stover mix composting.

Bioresource technology

Zhang W, Yu C, Wang X, Yin S, Chang X.
PMID: 34958903
Bioresour Technol. 2021 Dec 24;346:126626. doi: 10.1016/j.biortech.2021.126626. Epub 2021 Dec 24.

The objective of this study was to analyze the effects of additives (biochar (BC) and palygorskite (PG)) on predominant fungi succession throughout composting of corn stover/chicken manure mix to influence humic substances formation (HS). Results indicated that BC and...

NHS-IL12 and bintrafusp alfa combination therapy enhances antitumor activity in preclinical cancer models.

Translational oncology

Xu C, Marelli B, Qi J, Qin G, Yu H, Wang H, Jenkins MH, Lo KM, Lan Y.
PMID: 34954456
Transl Oncol. 2022 Feb;16:101322. doi: 10.1016/j.tranon.2021.101322. Epub 2021 Dec 23.

Combinatorial immunotherapy approaches are emerging as viable cancer therapeutic strategies for improving patient responses and outcomes. This study investigated whether two such immunotherapies, with complementary mechanisms of action, could enhance antitumor activity in murine tumor models. The immunocytokine NHS-IL12,...

The Next Challenge for Post-COVID-19 Clinics: Scale.

Chest

Yu E, Kelly B.
PMID: 35000722
Chest. 2022 Jan;161(1):e63. doi: 10.1016/j.chest.2021.07.045.

No abstract available.

Low-Dose Aspirin Prevents Kidney Damage in LPS-Induced Preeclampsia by Inhibiting the WNT5A and NF-κB Signaling Pathways.

Frontiers in endocrinology

Li G, Wei W, Suo L, Zhang C, Yu H, Liu H, Guo Q, Zhen X, Yu Y.
PMID: 33790866
Front Endocrinol (Lausanne). 2021 Mar 11;12:639592. doi: 10.3389/fendo.2021.639592. eCollection 2021.

Preeclampsia (PE) is a serious pregnancy-related disease, and patients usually present with a high inflammatory response. Previous studies have suggested that aspirin (ASP) may have a role in alleviating the pathogenesis of preeclampsia. However, whether ASP can improve kidney...

A Predictive Nomogram for Red Blood Cell Transfusion in Pheochromocytoma Surgery: A Study on Improving the Preoperative Management of Pheochromocytoma.

Frontiers in endocrinology

Guo Y, You L, Hu H, Tong A, Zhang X, Yan L, Zhang S.
PMID: 33790869
Front Endocrinol (Lausanne). 2021 Mar 11;12:647610. doi: 10.3389/fendo.2021.647610. eCollection 2021.

PURPOSE: Surgery is the major treatment option for pheochromocytoma but carries potential risks, including hemorrhage and hemodynamic instability. Even with laparoscopic adrenalectomy, intraoperative blood transfusion happens from time to time, but few studies have investigated risk factors. For the...

Journey of Poly(ethylene Glycol) in Living Cells.

ACS applied materials & interfaces

Yang J, Xu L, Di L, Su Y, Zhu X.
PMID: 34424662
ACS Appl Mater Interfaces. 2021 Sep 01;13(34):40267-40277. doi: 10.1021/acsami.1c09366. Epub 2021 Aug 23.

As the gold standard for stealth polymer materials, poly(ethylene glycol) (PEG) has been widely used in drug delivery with excellent properties such as low toxicity, reduced immunogenicity, good water solubility, and so forth. However, lack of understanding for the...

Icaritin inhibited cigarette smoke extract-induced CD8.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Li Q, Sun J, Cao Y, Liu B, Zhao Z, Hu L, Zhang H, Kong Q, Wu J, Dong J.
PMID: 35026517
Phytomedicine. 2021 Dec 24;96:153907. doi: 10.1016/j.phymed.2021.153907. Epub 2021 Dec 24.

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a disabling/fatal disease characterized by progressive pulmonary function decline, and there are currently few drugs that can effectively reverse the decline in lung function; therefore, it is necessary to find novel drug...

Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease.

European journal of medicinal chemistry

Shi Y, Zhang H, Song Q, Yu G, Liu Z, Zhong F, Tan Z, Liu X, Deng Y.
PMID: 35026532
Eur J Med Chem. 2022 Jan 05;230:114098. doi: 10.1016/j.ejmech.2021.114098. Epub 2022 Jan 05.

Based on multitarget-directed ligands approach, through two rounds of screening, a series of 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives were designed, synthesized and evaluated as innovative multifunctional agents against Alzheimer's disease. In vitro biological assays indicated that most of the hybrids were endowed...

High-risk phenotypes of genetic disease in a Neonatal Intensive Care Unit population.

Chinese medical journal

Xiao T, Ni Q, Chen H, Wang H, Yang L, Wu B, Cao Y, Cheng G, Wang L, Hu L, Mei H, Lu Y, Gong M, Dong X, Zhou W.
PMID: 35026772
Chin Med J (Engl). 2022 Jan 13; doi: 10.1097/CM9.0000000000001959. Epub 2022 Jan 13.

No abstract available.

Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging.

Aging cell

Lu J, Li S, Li X, Zhao W, Duan X, Gu X, Xu J, Yu B, Sigal LJ, Dong Z, Xie L, Fang M.
PMID: 33780118
Aging Cell. 2021 May;20(5):e13353. doi: 10.1111/acel.13353. Epub 2021 Mar 29.

MicroRNAs (miRNAs) regulate gene expression and thereby influence cell development and function. Numerous studies have shown the significant roles of miRNAs in regulating immune cells including natural killer (NK) cells. However, little is known about the role of miRNAs...

Carbon dots and gold nanoclusters assisted construction of a ratiometric fluorescent biosensor for detection of Gram-negative bacteria.

Food chemistry

Fu L, Chen Q, Jia L.
PMID: 34871851
Food Chem. 2021 Dec 01;374:131750. doi: 10.1016/j.foodchem.2021.131750. Epub 2021 Dec 01.

A core-satellite nanocomposite was prepared by encapsulating the photostable blue carbon dots (BCDs) in the core of silica as the reference signal readout, and the target-sensitive gold nanoclusters (AuNCs) covalently linked to the surface of silica as the respond...

The emerging role of circular RNAs in spinal cord injury.

Journal of orthopaedic translation

Peng Peng, Yu H, Yongjin Li, Huang J, Yao S, Xing C, Liu W, Zhang B, Feng S.
PMID: 34401327
J Orthop Translat. 2021 Jul 22;30:1-5. doi: 10.1016/j.jot.2021.06.001. eCollection 2021 Sep.

Spinal cord injury (SCI) is one kind of severe diseases with high mortality and morbidity worldwide, and lacks effective therapeutic interventions currently, which leads to not only permanent neurological impairments but also heavy social and economic burden. Recent studies...

Showing 9985 to 9996 of 52260 entries