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Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis.

Molecular metabolism

Mukherjee S, Chakraborty M, Ulmasov B, McCommis K, Zhang J, Carpenter D, Msengi EN, Haubner J, Guo C, Pike DP, Ghoshal S, Ford DA, Neuschwander-Tetri BA, Chakraborty A.
PMID: 34757046
Mol Metab. 2021 Oct 28;54:101364. doi: 10.1016/j.molmet.2021.101364. Epub 2021 Oct 28.

OBJECTIVE: Obesity and insulin resistance greatly increase the risk of nonalcoholic fatty liver disease and steatohepatitis (NAFLD/NASH). We have previously discovered that whole-body and adipocyte-specific Ip6k1deletion protects mice from high-fat-diet-induced obesity and insulin resistance due to improved adipocyte thermogenesis...

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Mukherjee S, Chakraborty M, Ulmasov B, et al. Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. Mol Metab. 2021;54:101364doi: 10.1016/j.molmet.2021.101364.
Mukherjee, S., Chakraborty, M., Ulmasov, B., McCommis, K., Zhang, J., Carpenter, D., Msengi, E. N., Haubner, J., Guo, C., Pike, D. P., Ghoshal, S., Ford, D. A., Neuschwander-Tetri, B. A., & Chakraborty, A. (2021). Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. Molecular metabolism, 54101364. https://doi.org/10.1016/j.molmet.2021.101364
Mukherjee, Sandip, et al. "Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis." Molecular metabolism vol. 54 (2021): 101364. doi: https://doi.org/10.1016/j.molmet.2021.101364
Mukherjee S, Chakraborty M, Ulmasov B, McCommis K, Zhang J, Carpenter D, Msengi EN, Haubner J, Guo C, Pike DP, Ghoshal S, Ford DA, Neuschwander-Tetri BA, Chakraborty A. Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. Mol Metab. 2021 Oct 28;54:101364. doi: 10.1016/j.molmet.2021.101364. Epub 2021 Oct 28. PMID: 34757046; PMCID: PMC8609165.
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Virome holds back a vaccine.

Nature reviews. Microbiology

York A.
PMID: 35022581
Nat Rev Microbiol. 2022 Jan 12; doi: 10.1038/s41579-022-00685-1. Epub 2022 Jan 12.

No abstract available.

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York A. Virome holds back a vaccine. Nat Rev Microbiol. 2022;doi: 10.1038/s41579-022-00685-1.
York, A. (2022). Virome holds back a vaccine. Nature reviews. Microbiology, . https://doi.org/10.1038/s41579-022-00685-1
York, Ashley. "Virome holds back a vaccine." Nature reviews. Microbiology vol. (2022). doi: https://doi.org/10.1038/s41579-022-00685-1
York A. Virome holds back a vaccine. Nat Rev Microbiol. 2022 Jan 12; doi: 10.1038/s41579-022-00685-1. Epub 2022 Jan 12. PMID: 35022581.
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Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules.

Scientific reports

Stoiber P, Scribani Rossi P, Pokharel N, Germany JL, York EA, Schaus SE, Hansen U.
PMID: 34876605
Sci Rep. 2021 Dec 07;11(1):23564. doi: 10.1038/s41598-021-02962-0.

Factor quinolinone inhibitors are promising anti-cancer compounds, initially characterized as specific inhibitors of the oncogenic transcription factor LSF (TFCP2). These compounds exert anti-proliferative activity at least in part by disrupting mitotic spindles. Herein, we report additional interphase consequences of...

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Stoiber P, Scribani Rossi P, Pokharel N, et al. Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules. Sci Rep. 2021;11(1):23564doi: 10.1038/s41598-021-02962-0.
Stoiber, P., Scribani Rossi, P., Pokharel, N., Germany, J. L., York, E. A., Schaus, S. E., & Hansen, U. (2021). Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules. Scientific reports, 11(1), 23564. https://doi.org/10.1038/s41598-021-02962-0
Stoiber, Patrick, et al. "Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules." Scientific reports vol. 11,1 (2021): 23564. doi: https://doi.org/10.1038/s41598-021-02962-0
Stoiber P, Scribani Rossi P, Pokharel N, Germany JL, York EA, Schaus SE, Hansen U. Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules. Sci Rep. 2021 Dec 07;11(1):23564. doi: 10.1038/s41598-021-02962-0. PMID: 34876605; PMCID: PMC8651680.
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Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity.

Current biology : CB

Carreira-Rosario A, York RA, Choi M, Doe CQ, Clandinin TR.
PMID: 34478644
Curr Biol. 2021 Dec 06;31(23):5341-5349.e4. doi: 10.1016/j.cub.2021.08.022. Epub 2021 Sep 02.

Neural activity sculpts circuit wiring in many animals. In vertebrates, patterned spontaneous network activity (PaSNA) generates sensory maps and establishes local circuits.

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Carreira-Rosario A, York RA, Choi M, et al. Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity. Curr Biol. 2021;31(23):5341-5349.e4doi: 10.1016/j.cub.2021.08.022.
Carreira-Rosario, A., York, R. A., Choi, M., Doe, C. Q., & Clandinin, T. R. (2021). Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity. Current biology : CB, 31(23), 5341-5349.e4. https://doi.org/10.1016/j.cub.2021.08.022
Carreira-Rosario, Arnaldo, et al. "Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity." Current biology : CB vol. 31,23 (2021): 5341-5349.e4. doi: https://doi.org/10.1016/j.cub.2021.08.022
Carreira-Rosario A, York RA, Choi M, Doe CQ, Clandinin TR. Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity. Curr Biol. 2021 Dec 06;31(23):5341-5349.e4. doi: 10.1016/j.cub.2021.08.022. Epub 2021 Sep 02. PMID: 34478644; PMCID: PMC8665011.
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Assessments of Physicians' Electrocardiogram Interpretation Skill: A Systematic Review.

Academic medicine : journal of the Association of American Medical Colleges

Cook DA, Oh SY, Pusic MV.
PMID: 33913438
Acad Med. 2021 Apr 27; doi: 10.1097/ACM.0000000000004140. Epub 2021 Apr 27.

PURPOSE: To identify features of instruments, test procedures, study design, and validity evidence in published studies of electrocardiogram (ECG) skill assessments.METHOD: The authors conducted a systematic review, searching MEDLINE, Embase, Cochrane CENTRAL, PsycINFO, CINAHL, ERIC, and Web of Science...

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Cook DA, Oh SY, Pusic MV. Assessments of Physicians' Electrocardiogram Interpretation Skill: A Systematic Review. Acad Med. 2021;doi: 10.1097/ACM.0000000000004140.
Cook, D. A., Oh, S. Y., & Pusic, M. V. (2021). Assessments of Physicians' Electrocardiogram Interpretation Skill: A Systematic Review. Academic medicine : journal of the Association of American Medical Colleges, . https://doi.org/10.1097/ACM.0000000000004140
Cook, David A, et al. "Assessments of Physicians' Electrocardiogram Interpretation Skill: A Systematic Review." Academic medicine : journal of the Association of American Medical Colleges vol. (2021). doi: https://doi.org/10.1097/ACM.0000000000004140
Cook DA, Oh SY, Pusic MV. Assessments of Physicians' Electrocardiogram Interpretation Skill: A Systematic Review. Acad Med. 2021 Apr 27; doi: 10.1097/ACM.0000000000004140. Epub 2021 Apr 27. PMID: 33913438.
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Longitudinal Research Databases in Medical Education: Facilitating the Study of Educational Outcomes Over Time and Across Institutions.

Andriole DA, Roberts NK, Cook DA, Durning SJ, Triola MM.
UIID-AD: 393
2010;85:1340-1346. doi: 10.1097/ACM.0b013e3181e5c050.

Many education research questions cannot be answered using participants from one institution or short periods of follow-up. In response to societal demands for accountability and evidence of effectiveness, new models of research must be developed to study the outcomes...

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Andriole DA, Roberts NK, Cook DA, et al. Longitudinal Research Databases in Medical Education: Facilitating the Study of Educational Outcomes Over Time and Across Institutions. 2010;85:1340-1346doi: 10.1097/ACM.0b013e3181e5c050.
Andriole, D. A., Roberts, N. K., Cook, D. A., Durning, S. J., & Triola, M. M. (2010). Longitudinal Research Databases in Medical Education: Facilitating the Study of Educational Outcomes Over Time and Across Institutions. 851340-1346. https://doi.org/10.1097/ACM.0b013e3181e5c050
Andriole, D A, et al. "Longitudinal Research Databases in Medical Education: Facilitating the Study of Educational Outcomes Over Time and Across Institutions." vol. 85 (2010): 1340-1346. doi: https://doi.org/10.1097/ACM.0b013e3181e5c050
Andriole DA, Roberts NK, Cook DA, Durning SJ, Triola MM. Longitudinal Research Databases in Medical Education: Facilitating the Study of Educational Outcomes Over Time and Across Institutions. 2010;85:1340-1346. doi: 10.1097/ACM.0b013e3181e5c050. UIID-AD: 393.
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A web-based course on complementary medicine for medical students and residents improves knowledge and changes attitudes.

Schwartz A, Cook DA, Gelula MH, Dupras DM, Lee MC, Bauer BA.
UIID-AD: 395
2007;19:230-238.

Background: There is a growing need to educate physicians about complementary and alternative medicine (CAM). Few introductory courses in CAM have been described. Purpose: To develop and evaluate an introductory course in CAM for medical students and residents. Method:...

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Schwartz A, Cook DA, Gelula MH, et al. A web-based course on complementary medicine for medical students and residents improves knowledge and changes attitudes. 2007;19:230-238
Schwartz, A., Cook, D. A., Gelula, M. H., Dupras, D. M., Lee, M. C., & Bauer, B. A. (2007). A web-based course on complementary medicine for medical students and residents improves knowledge and changes attitudes. 19230-238.
Schwartz, A, et al. "A web-based course on complementary medicine for medical students and residents improves knowledge and changes attitudes." vol. 19 (2007): 230-238.
Schwartz A, Cook DA, Gelula MH, Dupras DM, Lee MC, Bauer BA. A web-based course on complementary medicine for medical students and residents improves knowledge and changes attitudes. 2007;19:230-238. UIID-AD: 395.
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Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials.

Schwartz A, Cook DA, Gelula MH, Dupras DM.
UIID-AD: 394
2007;41:897-905. doi: 10.1111/j.1365-2923.2007.02822.x.

CONTEXT Adapting web-based (WB) instruction to learners' individual differences may enhance learning. OBJECTIVES This study aimed to investigate aptitude-treatment interactions between learning and cognitive styles and WB instructional methods. METHODS We carried out a factorial, randomised, controlled, crossover, post-test-only...

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Schwartz A, Cook DA, Gelula MH, et al. Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials. 2007;41:897-905doi: 10.1111/j.1365-2923.2007.02822.x.
Schwartz, A., Cook, D. A., Gelula, M. H., & Dupras, D. M. (2007). Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials. 41897-905. https://doi.org/10.1111/j.1365-2923.2007.02822.x
Schwartz, A, et al. "Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials." vol. 41 (2007): 897-905. doi: https://doi.org/10.1111/j.1365-2923.2007.02822.x
Schwartz A, Cook DA, Gelula MH, Dupras DM. Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials. 2007;41:897-905. doi: 10.1111/j.1365-2923.2007.02822.x. UIID-AD: 394.
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Showing 577 to 584 of 584 entries