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Showing 25 to 36 of 584 entries
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Reply to Letter: "Surgical Simulation: Seeing the Bigger Picture and Asking the Right Questions".

Annals of surgery

Zendejas B, Cook DA.
PMID: 25607763
Ann Surg. 2015 Aug;262(2):e51-2. doi: 10.1097/SLA.0000000000001138.

No abstract available.

A Semiempirical Quantum Model for Hydrogen-Bonded Nucleic Acid Base Pairs.

Journal of chemical theory and computation

Giese TJ, Sherer EC, Cramer CJ, York DM.
PMID: 26631671
J Chem Theory Comput. 2005 Nov;1(6):1275-85. doi: 10.1021/ct050102l.

An exploratory semiempirical Hamiltonian (PM3BP) is developed to model hydrogen bonding in nucleic acid base pairs. The PM3BP Hamiltonian is a novel reparametrization of the PM3 Hamiltonian designed to reproduce experimental base pair dimer enthalpies and high-level density-functional results....

A facile synthesis of perfluoroalkyl vinyl iodides and their palladium-mediated cross-coupling reactions.

The Journal of organic chemistry

Jennings MP, Cork EA, Ramachandran PV.
PMID: 11112601
J Org Chem. 2000 Dec 15;65(25):8763-6. doi: 10.1021/jo001318c.

Catalytic amounts of zinc, as low as 10 mol %, in the presence of trifluoroacetic acid (TFA) initiate the radical addition of perfluoroalkyl iodides to terminal alkynes with high regio- and stereoselectivities. Palladium-mediated cross-coupling of these (E)-perfluoroalkyl vinyl iodides...

On vanishing stimuli in instructional material.

Journal of the experimental analysis of behavior

COOK DA.
PMID: 13695238
J Exp Anal Behav. 1960 Oct;3:292.

No abstract available.

Accuracy of paramedic diagnosis of stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Zweifler RM, York D, U TT, Mendizabal JE, Rothrock JF.
PMID: 17895125
J Stroke Cerebrovasc Dis. 1998 Nov-Dec;7(6):446-8. doi: 10.1016/s1052-3057(98)80130-4.

BACKGROUND AND PURPOSE: Accurate prehospital diagnosis of acute stroke may lead to fewer delays in hospital presentation. In addition, prehospital personnel soon may be administering therapies to patients with presumed stroke. We sought to determine the sensitivity and positive...

Association between funding and quality of published medical education research.

JAMA

Reed DA, Cook DA, Beckman TJ, Levine RB, Kern DE, Wright SM.
PMID: 17785645
JAMA. 2007 Sep 05;298(9):1002-9. doi: 10.1001/jama.298.9.1002.

CONTEXT: Methodological shortcomings in medical education research are often attributed to insufficient funding, yet an association between funding and study quality has not been established.OBJECTIVES: To develop and evaluate an instrument for measuring the quality of education research studies...

The research we still are not doing: an agenda for the study of computer-based learning.

Academic medicine : journal of the Association of American Medical Colleges

Cook DA.
PMID: 15917356
Acad Med. 2005 Jun;80(6):541-8. doi: 10.1097/00001888-200506000-00005.

Media-comparative research-that is, the comparison of computer-based learning (CBL) to noncomputer instruction-is logically impossible because there are no valid comparison groups. Results from media-comparative studies are thus confounded and difficult to meaningfully interpret. In 1994, Friedman proposed that such...

Light Energy Distribution in the Brown Alga Macrocystis pyrifera (Giant Kelp).

Plant physiology

Fork DC, Herbert SK, Malkin S.
PMID: 16668047
Plant Physiol. 1991 Mar;95(3):731-9. doi: 10.1104/pp.95.3.731.

The brown alga Macrocystis pyrifera (giant kelp) was studied by a combination of fluorescence spectroscopy at 77 kelvin, room temperature modulated fluorimetry, and photoacoustic techniques to determine how light energy is partitioned between photosystems I and II in states...

The effects of osmotic tissue dehydration and air drying on morphology and energy transfer in two species of porphyra.

Plant physiology

Smith CM, Satoh K, Fork DC.
PMID: 16664729
Plant Physiol. 1986 Apr;80(4):843-7. doi: 10.1104/pp.80.4.843.

Studies were conducted to document the effects on morphology and energy transfer in photosynthesis of severe tissue dehydration induced either by air-drying or by immersing the tissues of two Porphyra species in hyperosmotic solutions. These studies showed that the...

Web-based learning: pros, cons and controversies.

Clinical medicine (London, England)

Cook DA.
PMID: 17348573
Clin Med (Lond). 2007 Jan-Feb;7(1):37-42. doi: 10.7861/clinmedicine.7-1-37.

Advantages of web-based learning (WBL) in medical education include overcoming barriers of distance and time, economies of scale, and novel instructional methods, while disadvantages include social isolation, up-front costs, and technical problems. Web-based learning is purported to facilitate individualised...

Insight into the role of Mg in hammerhead ribozyme catalysis from X-ray crystallography and molecular dynamics simulation.

Journal of chemical theory and computation

Lee TS, López CS, Martick M, Scott WG, York DM.
PMID: 19079784
J Chem Theory Comput. 2007 Mar;3(2):325-327. doi: 10.1021/ct6003142.

Results of a series of 12 ns molecular dynamics (MD) simulations of the reactant state (with and without a Mg(2+) ion), early and late transition state mimics are presented based on a recently reported crystal structure of a full-length...

Effect of an herbal extract Number Ten (NT) on body weight in rats.

Chinese medicine

York DA, Thomas S, Greenway FL, Liu Z, Rood JC.
PMID: 17868447
Chin Med. 2007 Sep 14;2:10. doi: 10.1186/1749-8546-2-10.

BACKGROUND: Chinese herbal extract Number Ten (NT) is a dietary herbal formulation prepared from rhubarb, ginger, astragalus, red sage and tumeric. This study tested the effectiveness of NT in reducing body weight gain in rats.METHODS: Sixty female Wistar rats...

Showing 25 to 36 of 584 entries