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Showing 13 to 24 of 1130 entries
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Prevalence of KRAS, BRAF, PI3K and EGFR mutations among Asian patients with metastatic colorectal cancer.

Oncology letters

Phua LC, Ng HW, Yeo AH, Chen E, Lo MS, Cheah PY, Chan EC, Koh PK, Ho HK.
PMID: 26622882
Oncol Lett. 2015 Oct;10(4):2519-2526. doi: 10.3892/ol.2015.3560. Epub 2015 Aug 03.

Mutations in oncogenes along the epidermal growth factor receptor (EGFR) signaling pathway have been implicated in the resistance to cetuximab in patients with metastatic colorectal cancer (mCRC). However, the relative significance of these mutations based on their frequencies of...

Dearomative Indole Bisfunctionalization via a Diastereoselective Palladium-Catalyzed Arylcyanation.

Organic letters

Petrone DA, Yen A, Zeidan N, Lautens M.
PMID: 26379033
Org Lett. 2015 Oct 02;17(19):4838-41. doi: 10.1021/acs.orglett.5b02403.

The first Pd-catalyzed dearomative indole bisfunctionalization via a diastereoselective arylcyanation is reported. This method facilitates the formation of diverse indoline scaffolds bearing congested stereocenters with high levels of diastereoselectivity. This also represents the first example of a cyanation mechanism...

Rhodium-Catalyzed Asymmetric Cycloisomerization and Parallel Kinetic Resolution of Racemic Oxabicycles.

Angewandte Chemie (International ed. in English)

Loh CC, Schmid M, Webster R, Yen A, Yazdi SK, Franke PT, Lautens M.
PMID: 27416818
Angew Chem Int Ed Engl. 2016 Aug 16;55(34):10074-8. doi: 10.1002/anie.201604937. Epub 2016 Jul 15.

While desymmetrizations by intermolecular asymmetric ring-opening reactions of oxabicyclic alkenes with various nucleophiles have been reported over the past two decades, the demonstration of an intramolecular variant is unknown. Reported herein is the first rhodium-catalyzed asymmetric cycloisomerization of meso-oxabicyclic...

Low-cost facile fabrication of flexible transparent copper electrodes by nanosecond laser ablation.

Advanced materials (Deerfield Beach, Fla.)

Paeng D, Yoo JH, Yeo J, Lee D, Kim E, Ko SH, Grigoropoulos CP.
PMID: 25821011
Adv Mater. 2015 May 06;27(17):2762-7. doi: 10.1002/adma.201500098. Epub 2015 Mar 27.

Low-cost Cu flexible transparent conducting electrodes (FTCEs) are fabricated by facile nanosecond laser ablation. The fabricated Cu FTCEs show excellent opto-electrical properties (transmittance: 83%, sheet resistance: 17.48 Ω sq(-1)) with outstanding mechanical durability. Successful demonstration of a touch-screen panel...

Highly stretchable and transparent metal nanowire heater for wearable electronics applications.

Advanced materials (Deerfield Beach, Fla.)

Hong S, Lee H, Lee J, Kwon J, Han S, Suh YD, Cho H, Shin J, Yeo J, Ko SH.
PMID: 26177729
Adv Mater. 2015 Aug 26;27(32):4744-51. doi: 10.1002/adma.201500917. Epub 2015 Jul 14.

A highly stretchable and transparent electrical heater is demonstrated by constructing a partially embedded silver nanowire percolative network on an elastic substrate. The stretchable network heater is applied on human wrists under real-time strain, bending, and twisting, and has...

Collective Experience: A Database-Fuelled, Inter-Disciplinary Team-Led Learning System.

Journal of computing science and engineering : JCSE

Celi LA, Mark RG, Lee J, Scott DJ, Panch T.
PMID: 23766887
J Comput Sci Eng. 2012 Mar 01;6(1):51-59. doi: 10.5626/JCSE.2012.6.1.51.

We describe the framework of a data-fuelled, interdisciplinary team-led learning system. The idea is to build models using patients from one's own institution whose features are similar to an index patient as regards an outcome of interest, in order...

Availability of tongue diagnosis system for assessing tongue coating thickness in patients with functional dyspepsia.

Evidence-based complementary and alternative medicine : eCAM

Kim J, Son J, Jang S, Nam DH, Han G, Yeo I, Ko SJ, Park JW, Ryu B, Kim J.
PMID: 24159343
Evid Based Complement Alternat Med. 2013;2013:348272. doi: 10.1155/2013/348272. Epub 2013 Sep 15.

Tongue diagnosis is an important procedure in traditional Korean medicine (TKM). In particular, tongue coating thickness (TCT) is deemed to show the progression of the disease. However, conventional tongue diagnosis has limitations because of various external factors. Therefore, it...

Never in mitosis gene A-related kinase 6 promotes cell proliferation of hepatocellular carcinoma via cyclin B modulation.

Oncology letters

Zhang B, Zhang H, Wang D, Han S, Wang K, Yao A, Li X.
PMID: 25120679
Oncol Lett. 2014 Sep;8(3):1163-1168. doi: 10.3892/ol.2014.2300. Epub 2014 Jun 30.

Never in mitosis gene A-related kinase (Nek) 6 is a recently identified Nek that is required for mitotic cell cycle progression; however, the role and mechanism of Nek6 activity during hepatocarcinogenesis is not well known. The aim of this...

Kinetic Studies of the Reactions of Pentacyanoferrate(II) Complexes with Peroxydisulfate.

Inorganic chemistry

Chen MH, Lee S, Liu S, Yeh A.
PMID: 11666479
Inorg Chem. 1996 Apr 24;35(9):2627-2629. doi: 10.1021/ic9505920.

Reactions of Fe(CN)(5)L(3-) (L = 4-aminopyridine (4-ampy), pyridine (py), 4,4'-bipyridine (4,4'-bpy), and pyrazine (pz)) with peroxydisulfate, Fe(CN)(5)L(3-) + S(2)O(8)(2-) right harpoon over left harpoon Fe(CN)(5)L(2-) + SO(4)(-) + SO(4)(2-), have been found to follow an outer-sphere electron transfer mechanism....

Oxidative dehydrogenation on the alpha-carbon of 4-pyridylacetonitrile complexes of pentaammineruthenium(II).

Inorganic chemistry

Liu S, Lee S, Wang S, Yeh A, Gau HM, Shao MY.
PMID: 11703111
Inorg Chem. 2001 Nov 19;40(24):6139-43. doi: 10.1021/ic000944p.

The oxidation of Ru(NH(3))(5)NCCH(2)py(2+) in 0.10 M HCl turns the solution from yellow to greenish blue with an absorption at lambda = 791 nm. The absorbance reaches its maximum value when the complex undergoes a two-electron oxidation. The IR...

Three-Dimensional Quantitative Analysis of Scintigraphic Tomographic Images after Elastic Transformation to a Template.

Surgical technology international

Goris ML, Maclean M, Pace WM, Yee A, Kwan A.
PMID: 12219283
Surg Technol Int. 2000 Oct;81-90.

The diagnostic information in scintigraphic images is generally not contained in specific morphological image attributes, but in the regional distribution of count rate densities across the organ volumes. In a subclass of scintigraphic images, the evaluation is actually based...

ansa-[(tert-Butylamino)(isodicyclopentadienyl)dimethylsilane]Zr(NMe2)2 prepared by an amine-elimination reaction.

Acta crystallographica. Section C, Crystal structure communications

Gallucci JC, Gentil S, Pirio N, Meunier P, Gallou F, Paquette LA.
PMID: 12682383
Acta Crystallogr C. 2003 Apr;59:M109-11. doi: 10.1107/s0108270103003172. Epub 2003 Mar 11.

An amine-elimination reaction was used to obtain the title compound, i.e. (N-tert-butyl-N-[[(1,2,3,3a,7a-eta)-4,5,6,7-tetrahydro-4,7-methano-1H-inden-2-yl]dimethylsilyl]amido-kappaN)bis(N-methylmethanaminato-kappaN)zirconium(IV) or [isodiCpSiMe(2)N-tert-butyl]Zr(NMe(2))(2) (Cp is cyclopentadienyl), [Zr(C(16)H(25)NSi)(C(2)H(6)N)(2)], in very good yield. Treatment of isodiCpHSiMe(2)NH-tert-butyl with Zr(NMe(2))(4) leads to the formation of a yellow solid that can be purified...

Showing 13 to 24 of 1130 entries