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Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions.

JCI insight

Templehof H, Moshe N, Avraham-Davidi I, Yaniv K.
PMID: 34236046
JCI Insight. 2021 Jul 08;6(13). doi: 10.1172/jci.insight.130399.

Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs, and LDLs and is essential for their production. Defects in ApoB synthesis and secretion result in several human diseases, including abetalipoproteinemia and familial hypobetalipoproteinemia (FHBL1). In addition, ApoB-related dyslipidemia...

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Templehof H, Moshe N, Avraham-Davidi I, et al. Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI Insight. 2021;6(13)doi: 10.1172/jci.insight.130399.
Templehof, H., Moshe, N., Avraham-Davidi, I., & Yaniv, K. (2021). Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI insight, 6(13), . https://doi.org/10.1172/jci.insight.130399
Templehof, Hanoch, et al. "Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions." JCI insight vol. 6,13 (2021). doi: https://doi.org/10.1172/jci.insight.130399
Templehof H, Moshe N, Avraham-Davidi I, Yaniv K. Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI Insight. 2021 Jul 08;6(13). doi: 10.1172/jci.insight.130399. PMID: 34236046; PMCID: PMC8410079.
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Differentiating between drug-sensitive and drug-resistant tuberculosis with machine learning for clinical and radiological features.

Quantitative imaging in medicine and surgery

Yang F, Yu H, Kantipudi K, Karki M, Kassim YM, Rosenthal A, Hurt DE, Yaniv Z, Jaeger S.
PMID: 34993110
Quant Imaging Med Surg. 2022 Jan;12(1):675-687. doi: 10.21037/qims-21-290.

BACKGROUND: Tuberculosis (TB) drug resistance is a worldwide public health problem that threatens progress made in TB care and control. Early detection of drug resistance is important for disease control, with discrimination between drug-resistant TB (DR-TB) and drug-sensitive TB...

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Yang F, Yu H, Kantipudi K, et al. Differentiating between drug-sensitive and drug-resistant tuberculosis with machine learning for clinical and radiological features. Quant Imaging Med Surg. 2022;12(1):675-687doi: 10.21037/qims-21-290.
Yang, F., Yu, H., Kantipudi, K., Karki, M., Kassim, Y. M., Rosenthal, A., Hurt, D. E., Yaniv, Z., & Jaeger, S. (2022). Differentiating between drug-sensitive and drug-resistant tuberculosis with machine learning for clinical and radiological features. Quantitative imaging in medicine and surgery, 12(1), 675-687. https://doi.org/10.21037/qims-21-290
Yang, Feng, et al. "Differentiating between drug-sensitive and drug-resistant tuberculosis with machine learning for clinical and radiological features." Quantitative imaging in medicine and surgery vol. 12,1 (2022): 675-687. doi: https://doi.org/10.21037/qims-21-290
Yang F, Yu H, Kantipudi K, Karki M, Kassim YM, Rosenthal A, Hurt DE, Yaniv Z, Jaeger S. Differentiating between drug-sensitive and drug-resistant tuberculosis with machine learning for clinical and radiological features. Quant Imaging Med Surg. 2022 Jan;12(1):675-687. doi: 10.21037/qims-21-290. PMID: 34993110; PMCID: PMC8666787.
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Radiation-Induced Oxidation Reactions of 2-Selenouracil in Aqueous Solutions: Comparison with Sulfur Analog of Uracil.

Molecules (Basel, Switzerland)

Skotnicki K, Janik I, Sadowska K, Leszczynska G, Bobrowski K.
PMID: 35011366
Molecules. 2021 Dec 27;27(1). doi: 10.3390/molecules27010133.

One-electron oxidation of 2-selenouracil (2-SeU) by hydroxyl (

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Skotnicki K, Janik I, Sadowska K, et al. Radiation-Induced Oxidation Reactions of 2-Selenouracil in Aqueous Solutions: Comparison with Sulfur Analog of Uracil. Molecules. 2021;27(1)doi: 10.3390/molecules27010133.
Skotnicki, K., Janik, I., Sadowska, K., Leszczynska, G., & Bobrowski, K. (2021). Radiation-Induced Oxidation Reactions of 2-Selenouracil in Aqueous Solutions: Comparison with Sulfur Analog of Uracil. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010133
Skotnicki, Konrad, et al. "Radiation-Induced Oxidation Reactions of 2-Selenouracil in Aqueous Solutions: Comparison with Sulfur Analog of Uracil." Molecules (Basel, Switzerland) vol. 27,1 (2021). doi: https://doi.org/10.3390/molecules27010133
Skotnicki K, Janik I, Sadowska K, Leszczynska G, Bobrowski K. Radiation-Induced Oxidation Reactions of 2-Selenouracil in Aqueous Solutions: Comparison with Sulfur Analog of Uracil. Molecules. 2021 Dec 27;27(1). doi: 10.3390/molecules27010133. PMID: 35011366.
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Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood.

Stroke

Bardugo A, Fishman B, Libruder C, Tanne D, Ram A, Hershkovitz Y, Zucker I, Furer A, Gilon R, Chodick G, Tiosano S, Derazne E, Tzur D, Afek A, Pinhas-Hamiel O, Bendor CD, Yaniv G, Rotem RS, Twig G.
PMID: 33980044
Stroke. 2021 Jun;52(6):2043-2052. doi: 10.1161/STROKEAHA.120.033595. Epub 2021 May 13.

[Figure: see text].

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Bardugo A, Fishman B, Libruder C, et al. Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood. Stroke. 2021;52(6):2043-2052doi: 10.1161/STROKEAHA.120.033595.
Bardugo, A., Fishman, B., Libruder, C., Tanne, D., Ram, A., Hershkovitz, Y., Zucker, I., Furer, A., Gilon, R., Chodick, G., Tiosano, S., Derazne, E., Tzur, D., Afek, A., Pinhas-Hamiel, O., Bendor, C. D., Yaniv, G., Rotem, R. S., & Twig, G. (2021). Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood. Stroke, 52(6), 2043-2052. https://doi.org/10.1161/STROKEAHA.120.033595
Bardugo, Aya, et al. "Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood." Stroke vol. 52,6 (2021): 2043-2052. doi: https://doi.org/10.1161/STROKEAHA.120.033595
Bardugo A, Fishman B, Libruder C, Tanne D, Ram A, Hershkovitz Y, Zucker I, Furer A, Gilon R, Chodick G, Tiosano S, Derazne E, Tzur D, Afek A, Pinhas-Hamiel O, Bendor CD, Yaniv G, Rotem RS, Twig G. Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood. Stroke. 2021 Jun;52(6):2043-2052. doi: 10.1161/STROKEAHA.120.033595. Epub 2021 May 13. PMID: 33980044.
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Kidney Transplantation in Times of Covid-19: Decision Analysis in the Canadian Context.

Canadian journal of kidney health and disease

Yanev I, Gagnon M, Cheng MP, Paraskevas S, Kumar D, Dragomir A, Sapir-Pichhadze R.
PMID: 34540237
Can J Kidney Health Dis. 2021 Sep 14;8:20543581211040332. doi: 10.1177/20543581211040332. eCollection 2021.

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic impacted transplant programs across Canada.OBJECTIVE: We evaluated the implications of delays in transplantation among Canadian end-stage kidney disease (ESKD) patients to allow pretransplant vaccination.DESIGN: We used a Markov microsimulation model and ESKD...

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Yanev I, Gagnon M, Cheng MP, et al. Kidney Transplantation in Times of Covid-19: Decision Analysis in the Canadian Context. Can J Kidney Health Dis. 2021;8:20543581211040332doi: 10.1177/20543581211040332.
Yanev, I., Gagnon, M., Cheng, M. P., Paraskevas, S., Kumar, D., Dragomir, A., & Sapir-Pichhadze, R. (2021). Kidney Transplantation in Times of Covid-19: Decision Analysis in the Canadian Context. Canadian journal of kidney health and disease, 820543581211040332. https://doi.org/10.1177/20543581211040332
Yanev, Ivan, et al. "Kidney Transplantation in Times of Covid-19: Decision Analysis in the Canadian Context." Canadian journal of kidney health and disease vol. 8 (2021): 20543581211040332. doi: https://doi.org/10.1177/20543581211040332
Yanev I, Gagnon M, Cheng MP, Paraskevas S, Kumar D, Dragomir A, Sapir-Pichhadze R. Kidney Transplantation in Times of Covid-19: Decision Analysis in the Canadian Context. Can J Kidney Health Dis. 2021 Sep 14;8:20543581211040332. doi: 10.1177/20543581211040332. eCollection 2021. PMID: 34540237; PMCID: PMC8447095.
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Ca.

Frontiers in physiology

Yang D, Morrell CH, Lyashkov AE, Tagirova Sirenko S, Zahanich I, Yaniv Y, Vinogradova TM, Ziman BD, Maltsev VA, Lakatta EG.
PMID: 34566668
Front Physiol. 2021 Sep 08;12:612770. doi: 10.3389/fphys.2021.612770. eCollection 2021.

Ca

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Yang D, Morrell CH, Lyashkov AE, et al. Ca. Front Physiol. 2021;12:612770doi: 10.3389/fphys.2021.612770.
Yang, D., Morrell, C. H., Lyashkov, A. E., Tagirova Sirenko, S., Zahanich, I., Yaniv, Y., Vinogradova, T. M., Ziman, B. D., Maltsev, V. A., & Lakatta, E. G. (2021). Ca. Frontiers in physiology, 12612770. https://doi.org/10.3389/fphys.2021.612770
Yang, Dongmei, et al. "Ca." Frontiers in physiology vol. 12 (2021): 612770. doi: https://doi.org/10.3389/fphys.2021.612770
Yang D, Morrell CH, Lyashkov AE, Tagirova Sirenko S, Zahanich I, Yaniv Y, Vinogradova TM, Ziman BD, Maltsev VA, Lakatta EG. Ca. Front Physiol. 2021 Sep 08;12:612770. doi: 10.3389/fphys.2021.612770. eCollection 2021. PMID: 34566668; PMCID: PMC8456031.
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Synus node dysfunction in heart failure is characterized by reduced CaMKII signaling.

The Journal of general physiology

Xue JB, Val-Blasco A, Davoodi M, Gómez S, Yaniv Y, Benitah JP, Gómez AM.
PMID: 34767009
J Gen Physiol. 2022 Sep 05;154(9). doi: 10.1085/jgp.2021ecc37. Epub 2021 Nov 12.

Heart failure (HF) is a complex syndrome in which death rates are over 50%. The main cause of death among HF patients is pump failure and ventricular arrhythmias, but severe bradycardia is also a common cause of sudden cardiac...

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Xue JB, Val-Blasco A, Davoodi M, et al. Synus node dysfunction in heart failure is characterized by reduced CaMKII signaling. J Gen Physiol. 2021;154(9)doi: 10.1085/jgp.2021ecc37.
Xue, J. B., Val-Blasco, A., Davoodi, M., Gómez, S., Yaniv, Y., Benitah, J. P., & Gómez, A. M. (2022). Synus node dysfunction in heart failure is characterized by reduced CaMKII signaling. The Journal of general physiology, 154(9), . https://doi.org/10.1085/jgp.2021ecc37
Xue, Jian-Bin, et al. "Synus node dysfunction in heart failure is characterized by reduced CaMKII signaling." The Journal of general physiology vol. 154,9 (2022). doi: https://doi.org/10.1085/jgp.2021ecc37
Xue JB, Val-Blasco A, Davoodi M, Gómez S, Yaniv Y, Benitah JP, Gómez AM. Synus node dysfunction in heart failure is characterized by reduced CaMKII signaling. J Gen Physiol. 2022 Sep 05;154(9). doi: 10.1085/jgp.2021ecc37. Epub 2021 Nov 12. PMID: 34767009.
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CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA.

Journal of neuroradiology = Journal de neuroradiologie

Nael K, Sakai Y, Larson J, Goldstein J, Deutsch J, Awad AJ, Pawha P, Aggarwal A, Fifi J, Deleacy R, Yaniv G, Wintermark M, Liebeskind DS, Shoirah H, Mocco J.
PMID: 34800563
J Neuroradiol. 2021 Nov 17; doi: 10.1016/j.neurad.2021.11.002. Epub 2021 Nov 17.

BACKGROUND & PURPOSE: Perfusion collateral index (PCI) has been recently defined as a promising measure of collateral status. We sought to compare collateral status assessed via CT-PCI in comparison to single-phase CTA and their relationship to outcome measures including...

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Nael K, Sakai Y, Larson J, et al. CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA. J Neuroradiol. 2021;doi: 10.1016/j.neurad.2021.11.002.
Nael, K., Sakai, Y., Larson, J., Goldstein, J., Deutsch, J., Awad, A. J., Pawha, P., Aggarwal, A., Fifi, J., Deleacy, R., Yaniv, G., Wintermark, M., Liebeskind, D. S., Shoirah, H., & Mocco, J. (2021). CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA. Journal of neuroradiology = Journal de neuroradiologie, . https://doi.org/10.1016/j.neurad.2021.11.002
Nael, Kambiz, et al. "CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA." Journal of neuroradiology = Journal de neuroradiologie vol. (2021). doi: https://doi.org/10.1016/j.neurad.2021.11.002
Nael K, Sakai Y, Larson J, Goldstein J, Deutsch J, Awad AJ, Pawha P, Aggarwal A, Fifi J, Deleacy R, Yaniv G, Wintermark M, Liebeskind DS, Shoirah H, Mocco J. CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA. J Neuroradiol. 2021 Nov 17; doi: 10.1016/j.neurad.2021.11.002. Epub 2021 Nov 17. PMID: 34800563.
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3.0 Tesla normative diffusivity in 3rd trimester fetal brain.

Neuroradiology

Segev M, Djurabayev B, Katorza E, Yaniv G, Hoffmann C, Shrot S.
PMID: 34820712
Neuroradiology. 2021 Nov 25; doi: 10.1007/s00234-021-02863-z. Epub 2021 Nov 25.

PURPOSE: Apparent diffusion coefficient (ADC) values in the developing fetus provide valuable information on the diagnosis and prognosis of prenatal brain pathologies. Normative ADC data has been previously established in 1.5 T MR scanners but lacking in 3.0 T...

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Segev M, Djurabayev B, Katorza E, et al. 3.0 Tesla normative diffusivity in 3rd trimester fetal brain. Neuroradiology. 2021;doi: 10.1007/s00234-021-02863-z.
Segev, M., Djurabayev, B., Katorza, E., Yaniv, G., Hoffmann, C., & Shrot, S. (2021). 3.0 Tesla normative diffusivity in 3rd trimester fetal brain. Neuroradiology, . https://doi.org/10.1007/s00234-021-02863-z
Segev, Maria, et al. "3.0 Tesla normative diffusivity in 3rd trimester fetal brain." Neuroradiology vol. (2021). doi: https://doi.org/10.1007/s00234-021-02863-z
Segev M, Djurabayev B, Katorza E, Yaniv G, Hoffmann C, Shrot S. 3.0 Tesla normative diffusivity in 3rd trimester fetal brain. Neuroradiology. 2021 Nov 25; doi: 10.1007/s00234-021-02863-z. Epub 2021 Nov 25. PMID: 34820712.
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Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing.

Journal of perinatal medicine

Yoffe L, Kuperman AA, Isakov O, Haguel D, Polsky AL, Farberov L, Pillar N, Gurevich V, Haviv I, Shomron N.
PMID: 34114389
J Perinat Med. 2021 Jun 11;49(9):1071-1083. doi: 10.1515/jpm-2021-0006. Print 2021 Nov 25.

OBJECTIVES: Preeclampsia is a dangerous pregnancy complication. The source of preeclampsia is unknown, though the placenta is believed to have a central role in its pathogenesis. An association between maternal infection and preeclampsia has been demonstrated, yet the involvement...

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Yoffe L, Kuperman AA, Isakov O, et al. Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing. J Perinat Med. 2021;49(9):1071-1083doi: 10.1515/jpm-2021-0006.
Yoffe, L., Kuperman, A. A., Isakov, O., Haguel, D., Polsky, A. L., Farberov, L., Pillar, N., Gurevich, V., Haviv, I., & Shomron, N. (2021). Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing. Journal of perinatal medicine, 49(9), 1071-1083. https://doi.org/10.1515/jpm-2021-0006
Yoffe, Liron, et al. "Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing." Journal of perinatal medicine vol. 49,9 (2021): 1071-1083. doi: https://doi.org/10.1515/jpm-2021-0006
Yoffe L, Kuperman AA, Isakov O, Haguel D, Polsky AL, Farberov L, Pillar N, Gurevich V, Haviv I, Shomron N. Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing. J Perinat Med. 2021 Jun 11;49(9):1071-1083. doi: 10.1515/jpm-2021-0006. Print 2021 Nov 25. PMID: 34114389.
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The effect of lifestyle intervention on cardiometabolic risk factors in mental health rehabilitation hostel residents at-risk: a cluster-randomized controlled 15-month trial.

International journal of obesity (2005)

Tsodikov F, Schechter M, Goldsmith R, Peleg L, Baloush-Kleinman V, Rozenberg A, Yanuv I, Gimelfarb Y, Mosenzon O, Endevelt R.
PMID: 35022545
Int J Obes (Lond). 2022 Jan 12; doi: 10.1038/s41366-022-01063-w. Epub 2022 Jan 12.

OBJECTIVE: Cardiometabolic disorders contribute to morbidity and mortality in people with severe mental illnesses (SMI), yet lifestyle-intervention efficacy in patients with SMI is unclear. Israel's unique mental-health rehabilitation hostels (MHRHs) provide housing to subjects with SMI. We tested how...

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Tsodikov F, Schechter M, Goldsmith R, et al. The effect of lifestyle intervention on cardiometabolic risk factors in mental health rehabilitation hostel residents at-risk: a cluster-randomized controlled 15-month trial. Int J Obes (Lond). 2022;doi: 10.1038/s41366-022-01063-w.
Tsodikov, F., Schechter, M., Goldsmith, R., Peleg, L., Baloush-Kleinman, V., Rozenberg, A., Yanuv, I., Gimelfarb, Y., Mosenzon, O., & Endevelt, R. (2022). The effect of lifestyle intervention on cardiometabolic risk factors in mental health rehabilitation hostel residents at-risk: a cluster-randomized controlled 15-month trial. International journal of obesity (2005), . https://doi.org/10.1038/s41366-022-01063-w
Tsodikov, Faina, et al. "The effect of lifestyle intervention on cardiometabolic risk factors in mental health rehabilitation hostel residents at-risk: a cluster-randomized controlled 15-month trial." International journal of obesity (2005) vol. (2022). doi: https://doi.org/10.1038/s41366-022-01063-w
Tsodikov F, Schechter M, Goldsmith R, Peleg L, Baloush-Kleinman V, Rozenberg A, Yanuv I, Gimelfarb Y, Mosenzon O, Endevelt R. The effect of lifestyle intervention on cardiometabolic risk factors in mental health rehabilitation hostel residents at-risk: a cluster-randomized controlled 15-month trial. Int J Obes (Lond). 2022 Jan 12; doi: 10.1038/s41366-022-01063-w. Epub 2022 Jan 12. PMID: 35022545.
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Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58.

Diabetes care

Cahn A, Wiviott SD, Mosenzon O, Goodrich EL, Murphy SA, Yanuv I, Rozenberg A, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Gause-Nilsson IAM, Langkilde AM, Sabatine MS, Raz I.
PMID: 35015847
Diabetes Care. 2022 Jan 10; doi: 10.2337/dc21-1744. Epub 2022 Jan 10.

OBJECTIVE: Current guidelines recommend prescribing SGLT2 inhibitors to patients with type 2 diabetes and established or at high risk for atherosclerotic cardiovascular disease (ASCVD), irrespective of HbA1c levels. We studied the association of HbA1c with cardiovascular and renal outcomes...

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Cahn A, Wiviott SD, Mosenzon O, et al. Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58. Diabetes Care. 2022;doi: 10.2337/dc21-1744.
Cahn, A., Wiviott, S. D., Mosenzon, O., Goodrich, E. L., Murphy, S. A., Yanuv, I., Rozenberg, A., Bhatt, D. L., Leiter, L. A., McGuire, D. K., Wilding, J. P. H., Gause-Nilsson, I. A. M., Langkilde, A. M., Sabatine, M. S., & Raz, I. (2022). Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58. Diabetes care, . https://doi.org/10.2337/dc21-1744
Cahn, Avivit, et al. "Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58." Diabetes care vol. (2022). doi: https://doi.org/10.2337/dc21-1744
Cahn A, Wiviott SD, Mosenzon O, Goodrich EL, Murphy SA, Yanuv I, Rozenberg A, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Gause-Nilsson IAM, Langkilde AM, Sabatine MS, Raz I. Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58. Diabetes Care. 2022 Jan 10; doi: 10.2337/dc21-1744. Epub 2022 Jan 10. PMID: 35015847.
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