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Showing 4477 to 4487 of 4487 entries
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Adverse drug reactions to trimethoprim-sulfamethoxazole in systemic lupus erythematosus.

Lupus

Izuka S, Yamashita H, Takahashi Y, Kaneko H.
PMID: 34304628
Lupus. 2021 Sep;30(10):1679-1683. doi: 10.1177/09612033211033985. Epub 2021 Jul 26.

OBJECTIVES: Trimethoprim-sulfamethoxazole (TMP-SMX), a prophylactic agent against pneumocystis pneumonia (PCP), can cause adverse drug reactions (ADRs), particularly in patients with systemic lupus erythematosus (SLE). However, the risk factors for ADRs remain unclear. Thus, we sought to examine the prevalence...

Epigenetic upregulation of TET2 is an independent poor prognostic factor for intrahepatic cholangiocarcinoma.

Virchows Archiv : an international journal of pathology

Yamashita H, Tourna A, Akita M, Itoh T, Chokshi S, Ajiki T, Fukumoto T, Youngson NA, Zen Y.
PMID: 34905094
Virchows Arch. 2021 Dec 14; doi: 10.1007/s00428-021-03251-x. Epub 2021 Dec 14.

Mutations in IDH1/2 and the epigenetic silencing of TET2 occur in leukaemia or glioma in a mutually exclusive manner. Although intrahepatic cholangiocarcinoma (iCCA) may harbour IDH1/2 mutations, the contribution of TET2 to carcinogenesis remains unknown. In the present study,...

Comparative accuracy of cervical cancer screening strategies in healthy asymptomatic women: a systematic review and network meta-analysis.

Scientific reports

Terasawa T, Hosono S, Sasaki S, Hoshi K, Hamashima Y, Katayama T, Hamashima C.
PMID: 34997127
Sci Rep. 2022 Jan 07;12(1):94. doi: 10.1038/s41598-021-04201-y.

To compare all available accuracy data on screening strategies for identifying cervical intraepithelial neoplasia grade ≥ 2 in healthy asymptomatic women, we performed a systematic review and network meta-analysis. MEDLINE and EMBASE were searched up to October 2020 for...

Overview of Drug Transporters in Human Placenta.

International journal of molecular sciences

Yamashita M, Markert UR.
PMID: 34884954
Int J Mol Sci. 2021 Dec 05;22(23). doi: 10.3390/ijms222313149.

The transport of drugs across the placenta is a point of great importance in pharmacotherapy during pregnancy. However, the knowledge of drug transport in pregnancy is mostly based on experimental clinical data, and the underlying biological mechanisms are not...

In Situ Exploration of Stimulus-Induced Emission Changes in Mechanochromic Dyes.

The journal of physical chemistry letters

Yamashita M, Nagai S, Ito S, Tachikawa T.
PMID: 34378940
J Phys Chem Lett. 2021 Aug 19;12(32):7826-7831. doi: 10.1021/acs.jpclett.1c02015. Epub 2021 Aug 11.

The development of in situ analysis techniques for visualizing and linking macro- and nanoscopic features of external stimulus-responsive materials is crucial for their rational design and applications. Herein, we investigate the mechanical stress-induced emission changes in electron donor-acceptor type...

Long-term risk of cancer development among anti-Th/To antibody-positive systemic sclerosis patients: comment on the article by Mecoli et al.

Arthritis & rheumatology (Hoboken, N.J.)

Yamashita Y, Yamano Y, Muro Y, Koizumi H, Takeichi T, Kondoh Y, Akiyama M.
PMID: 34351078
Arthritis Rheumatol. 2021 Aug 05; doi: 10.1002/art.41945. Epub 2021 Aug 05.

We read the report by Mecoli et al on the relationship between cancer and anti-Th/To antibodies (AThAs) in patients with systemic sclerosis (SSc) (1). It is interesting that the presence of AThAs was reported to confer a protective effect...

Acetabular Morphology in Patients with Developmental Dysplasia of the Hip with High Dislocation.

Hip & pelvis

Tateda K, Nagoya S, Suzuki D, Kosukegawa I, Yamashita T.
PMID: 33748023
Hip Pelvis. 2021 Mar;33(1):25-32. doi: 10.5371/hp.2021.33.1.25. Epub 2021 Mar 02.

PURPOSE: The current study aimed to investigate the morphology of the true acetabulum in developmental dysplasia of the hip (DDH) with high dislocation. A secondary was to evaluate the acetabular cup placement in patients with high dislocation who were...

Reconstruction of the Midfoot Area with Vascularized Chimeric Osteocutaneous Scapula Flap: A Case Report.

Plastic and reconstructive surgery. Global open

Arata J, Tsuge I, Kumakiri M, Yamashita T, Kaito S, Yong Y, Yamada S.
PMID: 33747685
Plast Reconstr Surg Glob Open. 2021 Mar 15;9(3):e3361. doi: 10.1097/GOX.0000000000003361. eCollection 2021 Mar.

We report a case of reconstruction of a left midfoot defect with a chimeric partial scapula and skin flap in a 20-year-old man. After radical debridement, bone and soft tissue defects were reconstructed with a chimeric scapula and skin...

Requirement of CRMP2 Phosphorylation in Neuronal Migration of Developing Mouse Cerebral Cortex and Hippocampus and Redundant Roles of CRMP1 and CRMP4.

Cerebral cortex (New York, N.Y. : 1991)

Yamazaki Y, Moizumi M, Nagai J, Hatashita Y, Cai T, Kolattukudy P, Inoue T, Goshima Y, Ohshima T.
PMID: 34297816
Cereb Cortex. 2021 Jul 23; doi: 10.1093/cercor/bhab228. Epub 2021 Jul 23.

The mammalian cerebral cortex is characterized by a 6-layer structure, and proper neuronal migration is critical for its formation. Cyclin-dependent kinase 5 (Cdk5) has been shown to be a critical kinase for neuronal migration. Several Cdk5 substrates have been...

Enantioselective hydrophosphonylation of .

Organic & biomolecular chemistry

Chassillan L, Yamashita Y, Yoo WJ, Toffano M, Guillot R, Kobayashi S, Vo-Thanh G.
PMID: 34870670
Org Biomol Chem. 2021 Dec 15;19(48):10560-10564. doi: 10.1039/d1ob01953h.

The enantioselective hydrophosphonylation of

MUC1-C Dictates Neuroendocrine Lineage Specification in Pancreatic Ductal Adenocarcinomas.

Carcinogenesis

Luan Z, Morimoto Y, Fushimi A, Yamashita N, Suo W, Bhattacharya A, Hagiwara M, Jin C, Kufe D.
PMID: 34657147
Carcinogenesis. 2021 Oct 17; doi: 10.1093/carcin/bgab097. Epub 2021 Oct 17.

Pancreatic ductal adenocarcinomas (PDAC) and poorly differentiated pancreatic neuroendocrine (NE) carcinomas are KRAS mutant malignancies with a potential common cell of origin. PDAC ductal, but not NE, lineage traits have been associated with cell-intrinsic activation of interferon (IFN) pathways....

Showing 4477 to 4487 of 4487 entries