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Showing 9985 to 9996 of 62137 entries
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Frequency-Dependent Effects on Coordination and Prefrontal Hemodynamics During Finger Force Production Tasks.

Frontiers in human neuroscience

Xu D, Shin N, Lee S, Park J.
PMID: 34733144
Front Hum Neurosci. 2021 Oct 18;15:721679. doi: 10.3389/fnhum.2021.721679. eCollection 2021.

Behavioral stability partially depends on the variability of net outcomes by means of the co-varied adjustment of individual elements such as multi-finger forces. The properties of cyclic actions affect stability and variability of the performance as well as the...

Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways.

Frontiers in pharmacology

Yang X, An X, Wang C, Gao F, Lin Y, Chen W, Deng Q, Xu D, Li S, Zhang P, Sun B, Hou Y, Wu J.
PMID: 34733156
Front Pharmacol. 2021 Oct 18;12:722907. doi: 10.3389/fphar.2021.722907. eCollection 2021.

Mechanical ventilation is an indispensable life-support treatment for acute respiratory failure in critically ill patients, which is generally believed to involve uncontrolled inflammatory responses. Oxytocin (OT) has been reported to be effective in animal models of acute lung injury....

Determination of tipping point in course of PM.

Journal of hazardous materials

Chen S, Li D, Yu D, Li M, Ye L, Jiang Y, Tang S, Zhang R, Xu C, Jiang S, Wang Z, Aschner M, Zheng Y, Chen L, Chen W.
PMID: 34933256
J Hazard Mater. 2021 Dec 16;426:128089. doi: 10.1016/j.jhazmat.2021.128089. Epub 2021 Dec 16.

The dynamic network biomarkers (DNBs) are designed to identify the tipping point and specific molecules in initiation of PM

[Mediating effect of physical activity on association between sedentary leisure-time and obesity indexes among hypertensive individuals].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

Zhou TY, Su J, Zhou JY, Tao R, Lu Y, Hua YJ, Jin JR, Guo Y, Lyu J, Chen ZM, Li LM, Wu M.
PMID: 34954975
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Dec 10;42(12):2125-2130. doi: 10.3760/cma.j.cn112338-20210112-00031.

No abstract available.

An integrated space-to-ground quantum communication network over 4,600 kilometres.

Nature

Chen YA, Zhang Q, Chen TY, Cai WQ, Liao SK, Zhang J, Chen K, Yin J, Ren JG, Chen Z, Han SL, Yu Q, Liang K, Zhou F, Yuan X, Zhao MS, Wang TY, Jiang X, Zhang L, Liu WY, Li Y, Shen Q, Cao Y, Lu CY, Shu R, Wang JY, Li L, Liu NL, Xu F, Wang XB, Peng CZ, Pan JW.
PMID: 33408416
Nature. 2021 Jan;589(7841):214-219. doi: 10.1038/s41586-020-03093-8. Epub 2021 Jan 06.

Quantum key distribution (QKD)

RNA-seq identifies long non-coding RNAs as potential therapeutic targets for human corneal endothelial dysfunction under oxidative stress.

Experimental eye research

Shan K, Qiu J, Zhou R, Gu J, Zhang X, Zhang C, Xiang J, Xu J.
PMID: 34728181
Exp Eye Res. 2021 Dec;213:108820. doi: 10.1016/j.exer.2021.108820. Epub 2021 Oct 30.

Human corneal endothelial cells (CECs) have limited ability to regenerate in vivo. Oxidative stress has been proposed as one potential reason. Understanding the mechanism of oxidative stress-induced CEC dysfunction might provide novel targets for improving CEC regenerative capacity, and...

ESR evidence for the stereospecific spin trapping of 5-alkyl-5-methyl-1-pyrroline N-oxides.

Magnetic resonance in chemistry : MRC

Zhang Y, Xu G.
PMID: 34034435
Magn Reson Chem. 1989 Sep;27(9):846-851. doi: 10.1002/mrc.1260270907.

The ability of ten cyclic nitrones, 5-alkyl-5-methyl-1-pyrroline N-oxides, to trap a variety of short-lived free radicals has been investigated using ESR spectroscopy. Stereospecific spin trapping by these nitrones has been demonstrated by comparison of the ESR spectra of their...

Low muscle mass and Charlson comorbidity index are risk factors for short-term postoperative prognosis of elderly patients with gastrointestinal tumor: a cross-sectional study.

BMC geriatrics

Wang J, Xu L, Huang S, Hui Q, Shi X, Zhang Q.
PMID: 34949161
BMC Geriatr. 2021 Dec 23;21(1):730. doi: 10.1186/s12877-021-02683-z.

BACKGROUND: Sarcopenia is one of the most frequent syndromes in older adults and one of its main characteristics is low muscle mass. Gastrointestinal tumor is a malignant disease with high incidence. This study aimed to investigate the risk factors...

Identification of .

RSC medicinal chemistry

Liu H, Jiang X, Gao X, Tian W, Xu C, Wang R, Xu Y, Wei L, Cao F, Li W.
PMID: 33479646
RSC Med Chem. 2020 Mar 11;11(3):411-418. doi: 10.1039/c9md00556k. eCollection 2020 Mar 01.

ATP binding cassette transporter A1 (ABCA1) is a critical transporter that mediates cellular cholesterol efflux from macrophages to apolipoprotein A-I (ApoA-I). Therefore, increasing the expression level of ABCA1 is anti-atherogenic and ABCA1 expression upregulators have become novel choices for...

circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade.

Cancer cell international

Wu SG, Zhou P, Chen JX, Lei J, Hua L, Dong Y, Hu M, Lian CL, Yang LC, Zhou J.
PMID: 34034740
Cancer Cell Int. 2021 May 25;21(1):277. doi: 10.1186/s12935-021-01985-x.

BACKGROUND: Precise quantification of microRNA is challenging since circulating mRNA and rRNA in the blood are usually degraded. Therefore, it is necessary to identify specific biomarkers for ovarian cancer. This study aimed to investigate candidate circular RNAs (circRNAs) involved...

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation.

Signal transduction and targeted therapy

Zhu R, Li L, Nguyen B, Seo J, Wu M, Seale T, Levis M, Duffield A, Hu Y, Small D.
PMID: 34024909
Signal Transduct Target Ther. 2021 May 24;6(1):186. doi: 10.1038/s41392-021-00578-4.

Tyrosine kinase inhibitors (TKIs) targeting FLT3 have shown activity but when used alone have achieved limited success in clinical trials, suggesting the need for combination with other drugs. We investigated the combination of FLT3 TKIs (Gilteritinib or Sorafenib), with...

OsMKKK70 regulates grain size and leaf angle in rice through the OsMKK4-OsMAPK6-OsWRKY53 signaling pathway.

Journal of integrative plant biology

Liu Z, Mei E, Tian X, He M, Tang J, Xu M, Liu J, Song L, Li X, Wang Z, Guan Q, Xu Q, Bu Q.
PMID: 34561955
J Integr Plant Biol. 2021 Dec;63(12):2043-2057. doi: 10.1111/jipb.13174. Epub 2021 Oct 18.

Grain size and leaf angle are key agronomic traits that determine final yields in rice. However, the underlying molecular mechanisms are not well understood. Here we demonstrate that the Oryza sativa Mitogen Activated Protein Kinase Kinase Kinase OsMKKK70 regulates...

Showing 9985 to 9996 of 62137 entries