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Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival.

Journal of the National Cancer Institute

Wenzel L, Osann K, McKinney C, Cella D, Fulci G, Scroggins MJ, Lankes HA, Wang V, Nephew KP, Maxwell GL, Mok SC, Conrads TP, Miller A, Mannel RS, Gray HJ, Hanjani P, Huh WK, Spirtos N, Leitao MM, Glaser G, Sharma SK, Santin AD, Sperduto P, Lele SB, Burger RA, Monk BJ, Birrer M.
PMID: 33729494
J Natl Cancer Inst. 2021 Oct 01;113(10):1369-1378. doi: 10.1093/jnci/djab034.

BACKGROUND: There is a critical need to identify patient characteristics associated with long-term ovarian cancer survival.METHODS: Quality of life (QOL), measured by the Functional Assessment of Cancer Therapy-Ovarian-Trial Outcome Index (FACT-O-TOI), including physical, functional, and ovarian-specific subscales, was compared...

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Wenzel L, Osann K, McKinney C, et al. Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival. J Natl Cancer Inst. 2021;113(10):1369-1378doi: 10.1093/jnci/djab034.
Wenzel, L., Osann, K., McKinney, C., Cella, D., Fulci, G., Scroggins, M. J., Lankes, H. A., Wang, V., Nephew, K. P., Maxwell, G. L., Mok, S. C., Conrads, T. P., Miller, A., Mannel, R. S., Gray, H. J., Hanjani, P., Huh, W. K., Spirtos, N., Leitao, M. M., Glaser, G., Sharma, S. K., Santin, A. D., Sperduto, P., Lele, S. B., Burger, R. A., Monk, B. J., & Birrer, M. (2021). Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival. Journal of the National Cancer Institute, 113(10), 1369-1378. https://doi.org/10.1093/jnci/djab034
Wenzel, Lari, et al. "Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival." Journal of the National Cancer Institute vol. 113,10 (2021): 1369-1378. doi: https://doi.org/10.1093/jnci/djab034
Wenzel L, Osann K, McKinney C, Cella D, Fulci G, Scroggins MJ, Lankes HA, Wang V, Nephew KP, Maxwell GL, Mok SC, Conrads TP, Miller A, Mannel RS, Gray HJ, Hanjani P, Huh WK, Spirtos N, Leitao MM, Glaser G, Sharma SK, Santin AD, Sperduto P, Lele SB, Burger RA, Monk BJ, Birrer M. Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival. J Natl Cancer Inst. 2021 Oct 01;113(10):1369-1378. doi: 10.1093/jnci/djab034. PMID: 33729494; PMCID: PMC8486331.
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Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance.

Translational lung cancer research

de Ruiter QMB, Fontana JR, Pritchard WF, Mauda-Havakuk M, Bakhutashvili I, Esparza-Trujillo JA, Varble NA, Verstege M, Xu S, Seifabadi R, Browning RF, Wood BJ, Karanian JW.
PMID: 34584862
Transl Lung Cancer Res. 2021 Aug;10(8):3627-3644. doi: 10.21037/tlcr-21-275.

BACKGROUND: Endobronchial navigation is performed in a variety of ways, none of which are meeting all the clinicians' needs required to reach diagnostic success in every patient. We sought to characterize precurved and steerable guiding sheaths (GS) in endobronchial...

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de Ruiter QMB, Fontana JR, Pritchard WF, et al. Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Transl Lung Cancer Res. 2021;10(8):3627-3644doi: 10.21037/tlcr-21-275.
de Ruiter, Q. M. B., Fontana, J. R., Pritchard, W. F., Mauda-Havakuk, M., Bakhutashvili, I., Esparza-Trujillo, J. A., Varble, N. A., Verstege, M., Xu, S., Seifabadi, R., Browning, R. F., Wood, B. J., & Karanian, J. W. (2021). Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Translational lung cancer research, 10(8), 3627-3644. https://doi.org/10.21037/tlcr-21-275
de Ruiter, Quirina M B, et al. "Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance." Translational lung cancer research vol. 10,8 (2021): 3627-3644. doi: https://doi.org/10.21037/tlcr-21-275
de Ruiter QMB, Fontana JR, Pritchard WF, Mauda-Havakuk M, Bakhutashvili I, Esparza-Trujillo JA, Varble NA, Verstege M, Xu S, Seifabadi R, Browning RF, Wood BJ, Karanian JW. Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Transl Lung Cancer Res. 2021 Aug;10(8):3627-3644. doi: 10.21037/tlcr-21-275. PMID: 34584862; PMCID: PMC8435394.
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The GOG partners: A program for industry sponsored clinical trials in gynecologic oncology within the GOG foundation.

Gynecologic oncology

Monk BJ, Coleman RL, Herzog TJ, Moore KN, O'Malley DM, Randall LM, Slomovitz BM, Eskander R, Pothuri B, Reese LL, Mannel RS, Copeland LJ.
PMID: 33722417
Gynecol Oncol. 2021 Jul;162(1):203-209. doi: 10.1016/j.ygyno.2021.03.010. Epub 2021 Mar 13.

The GOG Foundation, Inc. (GOG-F) is a non-profit 501(c)(3) organization with the purpose of promoting excellence in the quality and integrity of clinical and basic scientific research in the field of gynecologic malignancies. GOG Partners (GOG-P) is a program...

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Monk BJ, Coleman RL, Herzog TJ, et al. The GOG partners: A program for industry sponsored clinical trials in gynecologic oncology within the GOG foundation. Gynecol Oncol. 2021;162(1):203-209doi: 10.1016/j.ygyno.2021.03.010.
Monk, B. J., Coleman, R. L., Herzog, T. J., Moore, K. N., O'Malley, D. M., Randall, L. M., Slomovitz, B. M., Eskander, R., Pothuri, B., Reese, L. L., Mannel, R. S., & Copeland, L. J. (2021). The GOG partners: A program for industry sponsored clinical trials in gynecologic oncology within the GOG foundation. Gynecologic oncology, 162(1), 203-209. https://doi.org/10.1016/j.ygyno.2021.03.010
Monk, Bradley J, et al. "The GOG partners: A program for industry sponsored clinical trials in gynecologic oncology within the GOG foundation." Gynecologic oncology vol. 162,1 (2021): 203-209. doi: https://doi.org/10.1016/j.ygyno.2021.03.010
Monk BJ, Coleman RL, Herzog TJ, Moore KN, O'Malley DM, Randall LM, Slomovitz BM, Eskander R, Pothuri B, Reese LL, Mannel RS, Copeland LJ. The GOG partners: A program for industry sponsored clinical trials in gynecologic oncology within the GOG foundation. Gynecol Oncol. 2021 Jul;162(1):203-209. doi: 10.1016/j.ygyno.2021.03.010. Epub 2021 Mar 13. PMID: 33722417.
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Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study.

Gynecologic oncology

duPont NC, Enserro D, Brady MF, Moxley K, Walker JL, Cosgrove C, Bixel K, Tewari KS, Thaker P, Wahner Hendrickson AE, Rubin S, Fujiwara K, Casey AC, Soper J, Burger RA, Monk BJ.
PMID: 34857397
Gynecol Oncol. 2021 Nov 29; doi: 10.1016/j.ygyno.2021.11.013. Epub 2021 Nov 29.

BACKGROUND: Age and ethnicity are among several factors that influence overall survival (OS) in ovarian cancer. The study objective was to determine whether ethnicity and age were of prognostic significance in women enrolled in a clinical trial evaluating the...

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duPont NC, Enserro D, Brady MF, et al. Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecol Oncol. 2021;doi: 10.1016/j.ygyno.2021.11.013.
duPont, N. C., Enserro, D., Brady, M. F., Moxley, K., Walker, J. L., Cosgrove, C., Bixel, K., Tewari, K. S., Thaker, P., Wahner Hendrickson, A. E., Rubin, S., Fujiwara, K., Casey, A. C., Soper, J., Burger, R. A., & Monk, B. J. (2021). Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecologic oncology, . https://doi.org/10.1016/j.ygyno.2021.11.013
duPont, Nefertiti C, et al. "Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study." Gynecologic oncology vol. (2021). doi: https://doi.org/10.1016/j.ygyno.2021.11.013
duPont NC, Enserro D, Brady MF, Moxley K, Walker JL, Cosgrove C, Bixel K, Tewari KS, Thaker P, Wahner Hendrickson AE, Rubin S, Fujiwara K, Casey AC, Soper J, Burger RA, Monk BJ. Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecol Oncol. 2021 Nov 29; doi: 10.1016/j.ygyno.2021.11.013. Epub 2021 Nov 29. PMID: 34857397.
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Paravertebral anesthetic nerve block for pain control after peroral endoscopic myotomy.

Techniques and innovations in gastrointestinal endoscopy

Elmunzer BJ, Lewis BR, Miller KF, Wolf BJ, Zeiler L, Gutman DA, Elias P, Tansel A, Moran RA, Bolin ED.
PMID: 34870251
Tech Innov Gastrointest Endosc. 2021;23(4):297-303. doi: 10.1016/j.tige.2021.06.006. Epub 2021 Jun 24.

BACKGROUND: Excess post-operative opioid medication use can delay recovery and is associated with long-term misuse, addiction, and overdose. We aimed to explore the effect of pre-procedural thoracic paravertebral nerve block (PNB) on pain-related outcomes after POEM.METHODS: In this retrospective...

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Elmunzer BJ, Lewis BR, Miller KF, et al. Paravertebral anesthetic nerve block for pain control after peroral endoscopic myotomy. Tech Innov Gastrointest Endosc. 2021;23(4):297-303doi: 10.1016/j.tige.2021.06.006.
Elmunzer, B. J., Lewis, B. R., Miller, K. F., Wolf, B. J., Zeiler, L., Gutman, D. A., Elias, P., Tansel, A., Moran, R. A., & Bolin, E. D. (2021). Paravertebral anesthetic nerve block for pain control after peroral endoscopic myotomy. Techniques and innovations in gastrointestinal endoscopy, 23(4), 297-303. https://doi.org/10.1016/j.tige.2021.06.006
Elmunzer, B Joseph, et al. "Paravertebral anesthetic nerve block for pain control after peroral endoscopic myotomy." Techniques and innovations in gastrointestinal endoscopy vol. 23,4 (2021): 297-303. doi: https://doi.org/10.1016/j.tige.2021.06.006
Elmunzer BJ, Lewis BR, Miller KF, Wolf BJ, Zeiler L, Gutman DA, Elias P, Tansel A, Moran RA, Bolin ED. Paravertebral anesthetic nerve block for pain control after peroral endoscopic myotomy. Tech Innov Gastrointest Endosc. 2021;23(4):297-303. doi: 10.1016/j.tige.2021.06.006. Epub 2021 Jun 24. PMID: 34870251; PMCID: PMC8635293.
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Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis.

European journal of clinical pharmacology

Kim HB, Kim JH, Wolf BJ.
PMID: 34817624
Eur J Clin Pharmacol. 2021 Nov 24; doi: 10.1007/s00228-021-03255-1. Epub 2021 Nov 24.

PURPOSE: Several observational studies have presented conflicting results on the association between the use of proton pump inhibitors (PPIs) or histamine H2 receptor antagonist (H2RA) and the risk of coronavirus disease 2019 (COVID-19). This systematic review and meta-analysis aimed...

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Kim HB, Kim JH, Wolf BJ. Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis. Eur J Clin Pharmacol. 2021;doi: 10.1007/s00228-021-03255-1.
Kim, H. B., Kim, J. H., & Wolf, B. J. (2021). Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis. European journal of clinical pharmacology, . https://doi.org/10.1007/s00228-021-03255-1
Kim, Hong-Bae, et al. "Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis." European journal of clinical pharmacology vol. (2021). doi: https://doi.org/10.1007/s00228-021-03255-1
Kim HB, Kim JH, Wolf BJ. Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis. Eur J Clin Pharmacol. 2021 Nov 24; doi: 10.1007/s00228-021-03255-1. Epub 2021 Nov 24. PMID: 34817624; PMCID: PMC8611395.
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Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes.

International journal of environmental research and public health

Verga JU, Huff M, Owens D, Wolf BJ, Hardiman G.
PMID: 35010832
Int J Environ Res Public Health. 2022 Jan 05;19(1). doi: 10.3390/ijerph19010574.

Exposure to Endocrine Disrupting Chemicals (EDC) has been linked with several adverse outcomes. In this review, we examine EDCs that are pervasive in the environment and are of concern in the context of human, animal, and environmental health. We...

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Verga JU, Huff M, Owens D, et al. Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes. Int J Environ Res Public Health. 2022;19(1)doi: 10.3390/ijerph19010574.
Verga, J. U., Huff, M., Owens, D., Wolf, B. J., & Hardiman, G. (2022). Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes. International journal of environmental research and public health, 19(1), . https://doi.org/10.3390/ijerph19010574
Verga, Jacopo Umberto, et al. "Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes." International journal of environmental research and public health vol. 19,1 (2022). doi: https://doi.org/10.3390/ijerph19010574
Verga JU, Huff M, Owens D, Wolf BJ, Hardiman G. Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes. Int J Environ Res Public Health. 2022 Jan 05;19(1). doi: 10.3390/ijerph19010574. PMID: 35010832.
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Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer.

Gynecologic oncology

Fuh KC, Bookman MA, Liu JF, Coleman RL, Herzog TJ, Thaker PH, Monk BJ, Anderson R, McIntyre G, Rangwala R, Moore KN.
PMID: 34474927
Gynecol Oncol. 2021 Nov;163(2):254-261. doi: 10.1016/j.ygyno.2021.08.020. Epub 2021 Aug 30.

OBJECTIVE: GAS6 and AXL are expressed in high-grade serous ovarian cancer but not in normal ovarian tissue. AVB-500, a novel high affinity Fc-sAXL fusion protein, binds GAS6 preventing AXL signaling. This Phase 1b study (NCT03639246) evaluated safety, efficacy, and...

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Fuh KC, Bookman MA, Liu JF, et al. Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer. Gynecol Oncol. 2021;163(2):254-261doi: 10.1016/j.ygyno.2021.08.020.
Fuh, K. C., Bookman, M. A., Liu, J. F., Coleman, R. L., Herzog, T. J., Thaker, P. H., Monk, B. J., Anderson, R., McIntyre, G., Rangwala, R., & Moore, K. N. (2021). Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer. Gynecologic oncology, 163(2), 254-261. https://doi.org/10.1016/j.ygyno.2021.08.020
Fuh, Katherine C, et al. "Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer." Gynecologic oncology vol. 163,2 (2021): 254-261. doi: https://doi.org/10.1016/j.ygyno.2021.08.020
Fuh KC, Bookman MA, Liu JF, Coleman RL, Herzog TJ, Thaker PH, Monk BJ, Anderson R, McIntyre G, Rangwala R, Moore KN. Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer. Gynecol Oncol. 2021 Nov;163(2):254-261. doi: 10.1016/j.ygyno.2021.08.020. Epub 2021 Aug 30. PMID: 34474927.
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The COVID-19 pandemic and the search for structure: Social media and conspiracy theories.

Social and personality psychology compass

Dow BJ, Johnson AL, Wang CS, Whitson J, Menon T.
PMID: 34512798
Soc Personal Psychol Compass. 2021 Aug 04;e12636. doi: 10.1111/spc3.12636. Epub 2021 Aug 04.

The study outlines a model for how the COVID-19 pandemic has uniquely exacerbated the propagation of conspiracy beliefs and subsequent harmful behaviors. The pandemic has led to widespread disruption of cognitive and social structures. As people face these disruptions...

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Dow BJ, Johnson AL, Wang CS, et al. The COVID-19 pandemic and the search for structure: Social media and conspiracy theories. Soc Personal Psychol Compass. 2021;e12636doi: 10.1111/spc3.12636.
Dow, B. J., Johnson, A. L., Wang, C. S., Whitson, J., & Menon, T. (2021). The COVID-19 pandemic and the search for structure: Social media and conspiracy theories. Social and personality psychology compass, e12636. https://doi.org/10.1111/spc3.12636
Dow, Benjamin J, et al. "The COVID-19 pandemic and the search for structure: Social media and conspiracy theories." Social and personality psychology compass vol. (2021): e12636. doi: https://doi.org/10.1111/spc3.12636
Dow BJ, Johnson AL, Wang CS, Whitson J, Menon T. The COVID-19 pandemic and the search for structure: Social media and conspiracy theories. Soc Personal Psychol Compass. 2021 Aug 04;e12636. doi: 10.1111/spc3.12636. Epub 2021 Aug 04. PMID: 34512798; PMCID: PMC8420120.
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Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance.

Translational lung cancer research

de Ruiter QMB, Fontana JR, Pritchard WF, Mauda-Havakuk M, Bakhutashvili I, Esparza-Trujillo JA, Varble NA, Verstege M, Xu S, Seifabadi R, Browning RF, Wood BJ, Karanian JW.
PMID: 34584862
Transl Lung Cancer Res. 2021 Aug;10(8):3627-3644. doi: 10.21037/tlcr-21-275.

BACKGROUND: Endobronchial navigation is performed in a variety of ways, none of which are meeting all the clinicians' needs required to reach diagnostic success in every patient. We sought to characterize precurved and steerable guiding sheaths (GS) in endobronchial...

Cite
de Ruiter QMB, Fontana JR, Pritchard WF, et al. Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Transl Lung Cancer Res. 2021;10(8):3627-3644doi: 10.21037/tlcr-21-275.
de Ruiter, Q. M. B., Fontana, J. R., Pritchard, W. F., Mauda-Havakuk, M., Bakhutashvili, I., Esparza-Trujillo, J. A., Varble, N. A., Verstege, M., Xu, S., Seifabadi, R., Browning, R. F., Wood, B. J., & Karanian, J. W. (2021). Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Translational lung cancer research, 10(8), 3627-3644. https://doi.org/10.21037/tlcr-21-275
de Ruiter, Quirina M B, et al. "Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance." Translational lung cancer research vol. 10,8 (2021): 3627-3644. doi: https://doi.org/10.21037/tlcr-21-275
de Ruiter QMB, Fontana JR, Pritchard WF, Mauda-Havakuk M, Bakhutashvili I, Esparza-Trujillo JA, Varble NA, Verstege M, Xu S, Seifabadi R, Browning RF, Wood BJ, Karanian JW. Endovascular steerable and endobronchial precurved guiding sheaths for transbronchial needle delivery under augmented fluoroscopy and cone beam CT image guidance. Transl Lung Cancer Res. 2021 Aug;10(8):3627-3644. doi: 10.21037/tlcr-21-275. PMID: 34584862; PMCID: PMC8435394.
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Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study.

Gynecologic oncology

duPont NC, Enserro D, Brady MF, Moxley K, Walker JL, Cosgrove C, Bixel K, Tewari KS, Thaker P, Wahner Hendrickson AE, Rubin S, Fujiwara K, Casey AC, Soper J, Burger RA, Monk BJ.
PMID: 34857397
Gynecol Oncol. 2021 Nov 29; doi: 10.1016/j.ygyno.2021.11.013. Epub 2021 Nov 29.

BACKGROUND: Age and ethnicity are among several factors that influence overall survival (OS) in ovarian cancer. The study objective was to determine whether ethnicity and age were of prognostic significance in women enrolled in a clinical trial evaluating the...

Cite
duPont NC, Enserro D, Brady MF, et al. Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecol Oncol. 2021;doi: 10.1016/j.ygyno.2021.11.013.
duPont, N. C., Enserro, D., Brady, M. F., Moxley, K., Walker, J. L., Cosgrove, C., Bixel, K., Tewari, K. S., Thaker, P., Wahner Hendrickson, A. E., Rubin, S., Fujiwara, K., Casey, A. C., Soper, J., Burger, R. A., & Monk, B. J. (2021). Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecologic oncology, . https://doi.org/10.1016/j.ygyno.2021.11.013
duPont, Nefertiti C, et al. "Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study." Gynecologic oncology vol. (2021). doi: https://doi.org/10.1016/j.ygyno.2021.11.013
duPont NC, Enserro D, Brady MF, Moxley K, Walker JL, Cosgrove C, Bixel K, Tewari KS, Thaker P, Wahner Hendrickson AE, Rubin S, Fujiwara K, Casey AC, Soper J, Burger RA, Monk BJ. Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study. Gynecol Oncol. 2021 Nov 29; doi: 10.1016/j.ygyno.2021.11.013. Epub 2021 Nov 29. PMID: 34857397.
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Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

O'Malley DM, Neffa M, Monk BJ, Melkadze T, Huang M, Kryzhanivska A, Bulat I, Meniawy TM, Bagameri A, Wang EW, Doger de Speville Uribe B, Hegg R, Ortuzar Feliu W, Ancukiewicz M, Lugowska I.
PMID: 34932394
J Clin Oncol. 2021 Dec 21;JCO2102067. doi: 10.1200/JCO.21.02067. Epub 2021 Dec 21.

PURPOSE: Balstilimab (antiprogrammed death-1) and zalifrelimab (anticytotoxic T-lymphocyte-associated antigen-4) are two new checkpoint inhibitors emerging as promising investigational agents for the treatment of advanced cervical cancer. This phase II trial (ClinicalTrials.gov identifier: NCT03495882) evaluated the combination of balstilimab plus...

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O'Malley DM, Neffa M, Monk BJ, et al. Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study. J Clin Oncol. 2021;JCO2102067doi: 10.1200/JCO.21.02067.
O'Malley, D. M., Neffa, M., Monk, B. J., Melkadze, T., Huang, M., Kryzhanivska, A., Bulat, I., Meniawy, T. M., Bagameri, A., Wang, E. W., Doger de Speville Uribe, B., Hegg, R., Ortuzar Feliu, W., Ancukiewicz, M., & Lugowska, I. (2021). Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2102067. https://doi.org/10.1200/JCO.21.02067
O'Malley, David M, et al. "Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study." Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. (2021): JCO2102067. doi: https://doi.org/10.1200/JCO.21.02067
O'Malley DM, Neffa M, Monk BJ, Melkadze T, Huang M, Kryzhanivska A, Bulat I, Meniawy TM, Bagameri A, Wang EW, Doger de Speville Uribe B, Hegg R, Ortuzar Feliu W, Ancukiewicz M, Lugowska I. Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study. J Clin Oncol. 2021 Dec 21;JCO2102067. doi: 10.1200/JCO.21.02067. Epub 2021 Dec 21. PMID: 34932394.
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