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Showing 193 to 201 of 201 entries
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Impact of freeze-thaw processes on monoclonal antibody platform process development.

Biotechnology and bioengineering

Weber D, Sittig C, Hubbuch J.
PMID: 34170514
Biotechnol Bioeng. 2021 Oct;118(10):3914-3925. doi: 10.1002/bit.27867. Epub 2021 Jul 06.

Freezing of cell culture supernatant (CCS) is a standard procedure in process development of monoclonal antibody (mAb) platform processes as up- and downstream development are usually separated. In the manufacturing process of mAb, however, freezing is avoided, which poses...

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Weber D, Sittig C, Hubbuch J. Impact of freeze-thaw processes on monoclonal antibody platform process development. Biotechnol Bioeng. 2021;118(10):3914-3925doi: 10.1002/bit.27867.
Weber, D., Sittig, C., & Hubbuch, J. (2021). Impact of freeze-thaw processes on monoclonal antibody platform process development. Biotechnology and bioengineering, 118(10), 3914-3925. https://doi.org/10.1002/bit.27867
Weber, Dennis, et al. "Impact of freeze-thaw processes on monoclonal antibody platform process development." Biotechnology and bioengineering vol. 118,10 (2021): 3914-3925. doi: https://doi.org/10.1002/bit.27867
Weber D, Sittig C, Hubbuch J. Impact of freeze-thaw processes on monoclonal antibody platform process development. Biotechnol Bioeng. 2021 Oct;118(10):3914-3925. doi: 10.1002/bit.27867. Epub 2021 Jul 06. PMID: 34170514.
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Silicon nanocolumns on nanosphere lithography templated substrates: effects of sphere size and substrate temperature.

Journal of nanoscience and nanotechnology

Patzig C, Fuhrmann B, Leipner HS, Rauschenbach B.
PMID: 19435070
J Nanosci Nanotechnol. 2009 Mar;9(3):1985-91. doi: 10.1166/jnn.2009.367.

Glancing angle ion beam sputter deposition was used to grow regular arrays of Si nanocolumns with a nominal height of 650 nm at room temperature on polystyrene nanospheres with sphere diameters between 260 nm and 3550 nm, and at...

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Patzig C, Fuhrmann B, Leipner HS, et al. Silicon nanocolumns on nanosphere lithography templated substrates: effects of sphere size and substrate temperature. J Nanosci Nanotechnol. 2009;9(3):1985-91doi: 10.1166/jnn.2009.367.
Patzig, C., Fuhrmann, B., Leipner, H. S., & Rauschenbach, B. (2009). Silicon nanocolumns on nanosphere lithography templated substrates: effects of sphere size and substrate temperature. Journal of nanoscience and nanotechnology, 9(3), 1985-91. https://doi.org/10.1166/jnn.2009.367
Patzig, Christian, et al. "Silicon nanocolumns on nanosphere lithography templated substrates: effects of sphere size and substrate temperature." Journal of nanoscience and nanotechnology vol. 9,3 (2009): 1985-91. doi: https://doi.org/10.1166/jnn.2009.367
Patzig C, Fuhrmann B, Leipner HS, Rauschenbach B. Silicon nanocolumns on nanosphere lithography templated substrates: effects of sphere size and substrate temperature. J Nanosci Nanotechnol. 2009 Mar;9(3):1985-91. doi: 10.1166/jnn.2009.367. PMID: 19435070.
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De novo formation of phthalimide from ubiquitous phthalic acid derivatives during the drying process of tea (Camellia sinensis) and selected herbal infusions.

Food chemistry

Wittig M, Biller J, Nitsopoulos A, Friedle A.
PMID: 34915368
Food Chem. 2022 Apr 16;374:131544. doi: 10.1016/j.foodchem.2021.131544. Epub 2021 Nov 08.

It is well documented that under some circumstances phthalimide, a known degradation product of the fungicide folpet, can be formed as an artifact during gas chromatographic analysis. This fact explains one phthalimide source, but does not explain a great...

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Wittig M, Biller J, Nitsopoulos A, et al. De novo formation of phthalimide from ubiquitous phthalic acid derivatives during the drying process of tea (Camellia sinensis) and selected herbal infusions. Food Chem. 2021;374:131544doi: 10.1016/j.foodchem.2021.131544.
Wittig, M., Biller, J., Nitsopoulos, A., & Friedle, A. (2022). De novo formation of phthalimide from ubiquitous phthalic acid derivatives during the drying process of tea (Camellia sinensis) and selected herbal infusions. Food chemistry, 374131544. https://doi.org/10.1016/j.foodchem.2021.131544
Wittig, Maximilian, et al. "De novo formation of phthalimide from ubiquitous phthalic acid derivatives during the drying process of tea (Camellia sinensis) and selected herbal infusions." Food chemistry vol. 374 (2022): 131544. doi: https://doi.org/10.1016/j.foodchem.2021.131544
Wittig M, Biller J, Nitsopoulos A, Friedle A. De novo formation of phthalimide from ubiquitous phthalic acid derivatives during the drying process of tea (Camellia sinensis) and selected herbal infusions. Food Chem. 2022 Apr 16;374:131544. doi: 10.1016/j.foodchem.2021.131544. Epub 2021 Nov 08. PMID: 34915368.
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Mesenchymal Stromal Cell Transplantation Induces Regeneration of Large and Full-Thickness Cartilage Defect of the Temporomandibular Joint.

Cartilage

Gomez M, Wittig O, Diaz-Solano D, Cardier JE.
PMID: 32493042
Cartilage. 2021 Dec;13(1):1814S-1821S. doi: 10.1177/1947603520926711. Epub 2020 Jun 04.

OBJECTIVE: Cartilage damage (CD) in the temporomandibular joint (TMJ) continues being a major problem in maxillofacial field. Evidence suggests that cellular therapy may be used for repairing CD in the TMJ.DESIGN: A murine model of condyle CD (CCD) was...

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Gomez M, Wittig O, Diaz-Solano D, et al. Mesenchymal Stromal Cell Transplantation Induces Regeneration of Large and Full-Thickness Cartilage Defect of the Temporomandibular Joint. Cartilage. 2020;13(1):1814S-1821Sdoi: 10.1177/1947603520926711.
Gomez, M., Wittig, O., Diaz-Solano, D., & Cardier, J. E. (2021). Mesenchymal Stromal Cell Transplantation Induces Regeneration of Large and Full-Thickness Cartilage Defect of the Temporomandibular Joint. Cartilage, 13(1), 1814S-1821S. https://doi.org/10.1177/1947603520926711
Gomez, Marcos, et al. "Mesenchymal Stromal Cell Transplantation Induces Regeneration of Large and Full-Thickness Cartilage Defect of the Temporomandibular Joint." Cartilage vol. 13,1 (2021): 1814S-1821S. doi: https://doi.org/10.1177/1947603520926711
Gomez M, Wittig O, Diaz-Solano D, Cardier JE. Mesenchymal Stromal Cell Transplantation Induces Regeneration of Large and Full-Thickness Cartilage Defect of the Temporomandibular Joint. Cartilage. 2021 Dec;13(1):1814S-1821S. doi: 10.1177/1947603520926711. Epub 2020 Jun 04. PMID: 32493042.
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Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma.

Case reports in plastic surgery & hand surgery

Decilveo AP, Liebling MS, Golden AL, Wittig JC.
PMID: 34790836
Case Reports Plast Surg Hand Surg. 2021 Nov 11;8(1):175-180. doi: 10.1080/23320885.2021.1999246. eCollection 2021.

Adamantinoma is a malignant tumor that usually presents in adult men between 20 and 50 years. Due to its metastatic potential, differentiating Adamantinoma from Osteofibrous dysplasia is essential as treatment varies greatly. We present a case of limb salvage...

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Decilveo AP, Liebling MS, Golden AL, et al. Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma. Case Reports Plast Surg Hand Surg. 2021;8(1):175-180doi: 10.1080/23320885.2021.1999246.
Decilveo, A. P., Liebling, M. S., Golden, A. L., & Wittig, J. C. (2021). Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma. Case reports in plastic surgery & hand surgery, 8(1), 175-180. https://doi.org/10.1080/23320885.2021.1999246
Decilveo, Alexander P, et al. "Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma." Case reports in plastic surgery & hand surgery vol. 8,1 (2021): 175-180. doi: https://doi.org/10.1080/23320885.2021.1999246
Decilveo AP, Liebling MS, Golden AL, Wittig JC. Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma. Case Reports Plast Surg Hand Surg. 2021 Nov 11;8(1):175-180. doi: 10.1080/23320885.2021.1999246. eCollection 2021. PMID: 34790836; PMCID: PMC8592600.
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[No title available]

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Nast A, Häfner HM, Kolk A, Koscielny J, Kunte C, Löser C, Meissner M, Pokrywka A, Schirmer S, Scherer FD, Strömer K, Wetzig T, Dressler C.
PMID: 34661348
J Dtsch Dermatol Ges. 2021 Oct;19(10):1531-1547. doi: 10.1111/ddg.14522_g.

No abstract available.

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Nast A, Häfner HM, Kolk A, et al. S3-Leitlinie: Umgang mit Antikoagulanzien und Thrombozytenaggregationshemmern bei Operationen an der Haut. . J Dtsch Dermatol Ges. 2021;19(10):1531-1547doi: 10.1111/ddg.14522_g.
Nast, A., Häfner, H. M., Kolk, A., Koscielny, J., Kunte, C., Löser, C., Meissner, M., Pokrywka, A., Schirmer, S., Scherer, F. D., Strömer, K., Wetzig, T., & Dressler, C. (2021). S3-Leitlinie: Umgang mit Antikoagulanzien und Thrombozytenaggregationshemmern bei Operationen an der Haut. . Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 19(10), 1531-1547. https://doi.org/10.1111/ddg.14522_g
Nast, Alexander, et al. "S3-Leitlinie: Umgang mit Antikoagulanzien und Thrombozytenaggregationshemmern bei Operationen an der Haut." . Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG vol. 19,10 (2021): 1531-1547. doi: https://doi.org/10.1111/ddg.14522_g
Nast A, Häfner HM, Kolk A, Koscielny J, Kunte C, Löser C, Meissner M, Pokrywka A, Schirmer S, Scherer FD, Strömer K, Wetzig T, Dressler C. S3-Leitlinie: Umgang mit Antikoagulanzien und Thrombozytenaggregationshemmern bei Operationen an der Haut. . J Dtsch Dermatol Ges. 2021 Oct;19(10):1531-1547. doi: 10.1111/ddg.14522_g. German. PMID: 34661348.
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The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB.

Molecular cancer therapeutics

Prüser JL, Ramer R, Wittig F, Ivanov I, Merkord J, Hinz B.
PMID: 33632876
Mol Cancer Ther. 2021 May;20(5):787-802. doi: 10.1158/1535-7163.MCT-20-0589. Epub 2021 Feb 25.

A targeted modulation of the endocannabinoid system is currently discussed as a promising strategy for cancer treatment. An important enzyme for the endocannabinoid metabolism is the monoacylglycerol lipase (MAGL), which catalyzes the degradation of 2-arachidonoylglycerol (2-AG) to glycerol and...

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Prüser JL, Ramer R, Wittig F, et al. The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB. Mol Cancer Ther. 2021;20(5):787-802doi: 10.1158/1535-7163.MCT-20-0589.
Prüser, J. L., Ramer, R., Wittig, F., Ivanov, I., Merkord, J., & Hinz, B. (2021). The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB. Molecular cancer therapeutics, 20(5), 787-802. https://doi.org/10.1158/1535-7163.MCT-20-0589
Prüser, Jan Lukas, et al. "The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB." Molecular cancer therapeutics vol. 20,5 (2021): 787-802. doi: https://doi.org/10.1158/1535-7163.MCT-20-0589
Prüser JL, Ramer R, Wittig F, Ivanov I, Merkord J, Hinz B. The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB. Mol Cancer Ther. 2021 May;20(5):787-802. doi: 10.1158/1535-7163.MCT-20-0589. Epub 2021 Feb 25. PMID: 33632876.
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Is There Value in Pathology Specimens in Routine Total Hip and Knee Arthroplasty?.

Cureus

Koss J, Goyette D, Patel J, Harrington CJ, Mazzei C, Wittig JC, Dundon J.
PMID: 33659136
Cureus. 2021 Jan 30;13(1):e13005. doi: 10.7759/cureus.13005.

Background Routine analysis of bone specimens in total joint arthroplasty (TJA) is mandatory at many institutions. The purpose of this study was to determine if mandatory routine TJA specimen analysis alters patient care or if they represent an unnecessary...

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Koss J, Goyette D, Patel J, et al. Is There Value in Pathology Specimens in Routine Total Hip and Knee Arthroplasty?. Cureus. 2021;13(1):e13005doi: 10.7759/cureus.13005.
Koss, J., Goyette, D., Patel, J., Harrington, C. J., Mazzei, C., Wittig, J. C., & Dundon, J. (2021). Is There Value in Pathology Specimens in Routine Total Hip and Knee Arthroplasty?. Cureus, 13(1), e13005. https://doi.org/10.7759/cureus.13005
Koss, Justin, et al. "Is There Value in Pathology Specimens in Routine Total Hip and Knee Arthroplasty?." Cureus vol. 13,1 (2021): e13005. doi: https://doi.org/10.7759/cureus.13005
Koss J, Goyette D, Patel J, Harrington CJ, Mazzei C, Wittig JC, Dundon J. Is There Value in Pathology Specimens in Routine Total Hip and Knee Arthroplasty?. Cureus. 2021 Jan 30;13(1):e13005. doi: 10.7759/cureus.13005. PMID: 33659136; PMCID: PMC7919613.
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Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction.

The Journal of clinical investigation

Keller TCS, Lim L, Shewale SV, McDaid K, Martí-Pàmies Í, Tang AT, Wittig C, Guerrero AA, Sterling S, Leu NA, Scherrer-Crosbie M, Gimotty PA, Kahn ML.
PMID: 34403369
J Clin Invest. 2021 Oct 15;131(20). doi: 10.1172/JCI147070.

In recent decades, treatments for myocardial infarction (MI), such as stem and progenitor cell therapy, have attracted considerable scientific and clinical attention but failed to improve patient outcomes. These efforts indicate that more rigorous mechanistic and functional testing of...

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Keller TCS, Lim L, Shewale SV, et al. Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction. J Clin Invest. 2021;131(20)doi: 10.1172/JCI147070.
Keller, T. C. S., Lim, L., Shewale, S. V., McDaid, K., Martí-Pàmies, �. �., Tang, A. T., Wittig, C., Guerrero, A. A., Sterling, S., Leu, N. A., Scherrer-Crosbie, M., Gimotty, P. A., & Kahn, M. L. (2021). Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction. The Journal of clinical investigation, 131(20), . https://doi.org/10.1172/JCI147070
Keller, T C Stevenson, et al. "Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction." The Journal of clinical investigation vol. 131,20 (2021). doi: https://doi.org/10.1172/JCI147070
Keller TCS, Lim L, Shewale SV, McDaid K, Martí-Pàmies Í, Tang AT, Wittig C, Guerrero AA, Sterling S, Leu NA, Scherrer-Crosbie M, Gimotty PA, Kahn ML. Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction. J Clin Invest. 2021 Oct 15;131(20). doi: 10.1172/JCI147070. PMID: 34403369; PMCID: PMC8516448.
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Showing 193 to 201 of 201 entries