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Showing 361 to 371 of 371 entries
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TLR4 Signaling Contributes to Post-Traumatic Epileptogenesis Through Insertion of Inwardly Rectifying AMPA Receptors: Not a Happy CP-AMPAR.

Epilepsy currents

Lillis KP.
PMID: 34025258
Epilepsy Curr. 2020 Sep 10;20(6):375-377. eCollection 2020.

No abstract available.

Sensei: how many samples to tell a change in cell type abundance?.

BMC bioinformatics

Liang S, Willis J, Dou J, Mohanty V, Huang Y, Vilar E, Chen K.
PMID: 34983369
BMC Bioinformatics. 2022 Jan 04;23(1):2. doi: 10.1186/s12859-021-04526-5.

Cellular heterogeneity underlies cancer evolution and metastasis. Advances in single-cell technologies such as single-cell RNA sequencing and mass cytometry have enabled interrogation of cell type-specific expression profiles and abundance across heterogeneous cancer samples obtained from clinical trials and preclinical...

Post-exercise accumulation of interstitial lung water is greater in hypobaric than normobaric hypoxia in adults born prematurely.

Respiratory physiology & neurobiology

Debevec T, Poussel M, Osredkar D, Willis SJ, Sartori C, Millet GP.
PMID: 34890833
Respir Physiol Neurobiol. 2021 Dec 07;297:103828. doi: 10.1016/j.resp.2021.103828. Epub 2021 Dec 07.

We aimed to gauge the interstitial lung water accumulation following moderate-intensity exercise under normobaric and hypobaric hypoxic conditions in a group of preterm born but otherwise healthy young adults. Sixteen pre-term-born individuals (age = 21±2yrs.; gestational age = 29±3wk.;...

Designing and controlling the properties of transition metal oxide quantum materials.

Nature materials

Ahn C, Cavalleri A, Georges A, Ismail-Beigi S, Millis AJ, Triscone JM.
PMID: 33941911
Nat Mater. 2021 Nov;20(11):1462-1468. doi: 10.1038/s41563-021-00989-2. Epub 2021 May 03.

This Perspective addresses the design, creation, characterization and control of synthetic quantum materials with strong electronic correlations. We show how emerging synergies between theoretical/computational approaches and materials design/experimental probes are driving recent advances in the discovery, understanding and control...

Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.

Journal of medicinal chemistry

Steadman D, Atkinson BN, Zhao Y, Willis NJ, Frew S, Monaghan A, Patel C, Armstrong E, Costelloe K, Magno L, Bictash M, Jones EY, Fish PV, Svensson F.
PMID: 34939789
J Med Chem. 2022 Jan 13;65(1):562-578. doi: 10.1021/acs.jmedchem.1c01735. Epub 2021 Dec 23.

Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Inhibitors of Notum could be of use in diseases where dysfunctional Notum activity is an underlying cause....

Comparative effectiveness analysis of first-line immunotherapy versus chemotherapy in metastatic urothelial carcinoma of the bladder.

Urologic oncology

Chakiryan NH, Jiang DD, Gillis KA, Green E, Hajiran A, Hugar L, Zemp L, Zhang J, Jain R, Chahoud J, Li R, Sexton W, Manley BJ, Gilbert SM.
PMID: 34426068
Urol Oncol. 2021 Aug 20; doi: 10.1016/j.urolonc.2021.07.030. Epub 2021 Aug 20.

BACKGROUND: Clinical trials have not shown a significant overall survival (OS) difference between chemotherapy and immunotherapy as first-line agents in metastatic urothelial carcinoma (UC). However, the generalizability of these findings in a real-world setting has not yet been evaluated...

Phonon-induced disorder in dynamics of optically pumped metals from nonlinear electron-phonon coupling.

Nature communications

Sous J, Kloss B, Kennes DM, Reichman DR, Millis AJ.
PMID: 34608144
Nat Commun. 2021 Oct 04;12(1):5803. doi: 10.1038/s41467-021-26030-3.

The non-equilibrium dynamics of matter excited by light may produce electronic phases, such as laser-induced high-transition-temperature superconductivity, that do not exist in equilibrium. Here we simulate the dynamics of a metal driven at initial time by a spatially uniform...

Etoposide-Bound Magnetic Nanoparticles Designed for Remote Targeting of Cancer Cells Disseminated Within Cerebrospinal Fluid Pathways.

Frontiers in neurology

Engelhard HH, Willis AJ, Hussain SI, Papavasiliou G, Banner DJ, Kwasnicki A, Lakka SS, Hwang S, Shokuhfar T, Morris SC, Liu B.
PMID: 33329349
Front Neurol. 2020 Nov 27;11:596632. doi: 10.3389/fneur.2020.596632. eCollection 2020.

Magnetic nanoparticles (MNPs) have potential for enhancing drug delivery in selected cancer patients, including those which have cells that have disseminated within cerebrospinal fluid (CSF) pathways. Here, we present data related to the creation and

Author Correction: Deep learning algorithm predicts diabetic retinopathy progression in individual patients.

NPJ digital medicine

Arcadu F, Benmansour F, Maunz A, Willis J, Haskova Z, Prunotto M.
PMID: 33293570
NPJ Digit Med. 2020 Dec 08;3(1):160. doi: 10.1038/s41746-020-00365-5.

A Correction to this paper has been published: https://doi.org/10.1038/s41746-020-00365-5.

Post-exercise accumulation of interstitial lung water is greater in hypobaric than normobaric hypoxia in adults born prematurely.

Respiratory physiology & neurobiology

Debevec T, Poussel M, Osredkar D, Willis SJ, Sartori C, Millet GP.
PMID: 34890833
Respir Physiol Neurobiol. 2021 Dec 07;297:103828. doi: 10.1016/j.resp.2021.103828. Epub 2021 Dec 07.

We aimed to gauge the interstitial lung water accumulation following moderate-intensity exercise under normobaric and hypobaric hypoxic conditions in a group of preterm born but otherwise healthy young adults. Sixteen pre-term-born individuals (age = 21±2yrs.; gestational age = 29±3wk.;...

Educational and health impact of the Baume Report: 'A Cutting Edge: Australia's Surgical Workforce'.

Hillis DJ, Gorton MW, Barraclough BH, Beckett D.
UIID-AD: 121
2014;38:487-494. doi: 10.1071/ah14062.

Objectives The Baume Report (1994) on Australia's surgical workforce had the potential to impact upon the health and educational sectors. This paper analyses the recommendations of this report and their impact at the time and 15 years later (2009)....

Showing 361 to 371 of 371 entries