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Showing 49 to 60 of 126 entries
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Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E.

Frontiers in bioengineering and biotechnology

Gilman KE, Camden JM, Woods LT, Weisman GA, Limesand KH.
PMID: 34381764
Front Bioeng Biotechnol. 2021 Jul 21;9:697671. doi: 10.3389/fbioe.2021.697671. eCollection 2021.

Annually, >600,000 new cases of head and neck cancer (HNC) are diagnosed worldwide with primary treatment being surgery and radiotherapy. During ionizing radiation (IR) treatment of HNC, healthy salivary glands are collaterally damaged, leading to loss of function that...

Convolutional Neural Networks for Automated PET/CT Detection of Diseased Lymph Node Burden in Patients with Lymphoma.

Radiology. Artificial intelligence

Weisman AJ, Kieler MW, Perlman SB, Hutchings M, Jeraj R, Kostakoglu L, Bradshaw TJ.
PMID: 33937842
Radiol Artif Intell. 2020 Sep 02;2(5):e200016. doi: 10.1148/ryai.2020200016. eCollection 2020 Sep.

PURPOSE: To automatically detect lymph nodes involved in lymphoma on fluorine 18 (MATERIALS AND METHODS: In this retrospective study, baseline disease of 90 patients with lymphoma was segmented on RESULTS: Across all 90 patients, a range of 0-61 nodes...

Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis.

Shock (Augusta, Ga.)

Jones TK, Reilly JP, Anderson BJ, Miano TA, Dunn TG, Weisman AR, Agyekum R, Feng R, Ittner CAG, Shashaty MGS, Meyer NJ.
PMID: 34265829
Shock. 2022 Jan 01;57(1):41-47. doi: 10.1097/SHK.0000000000001833.

BACKGROUND: Matrix Metalloproteinases (MMP) respond to tissue damage during sepsis. Higher plasma concentrations of MMPs and the tissue-inhibitor of matrix metalloproteinases (TIMP) have been reported in sepsis compared with healthy controls. The objective of this study was to examine...

Suicidal ideation and executive functioning in pediatric cancer.

Psycho-oncology

Sharkey CM, Hardy KK, Gioia A, Weisman H, Walsh K.
PMID: 34797956
Psychooncology. 2021 Nov 19; doi: 10.1002/pon.5858. Epub 2021 Nov 19.

OBJECTIVE: Neurocognitive impairments and psychological distress are among the most common difficulties experienced by children treated for cancer. Elevated rates of suicidal ideation (SI) are documented among cancer survivors, and a link between neurocognitive deficits and SI is evident,...

The Association of Tumor Necrosis Factor Inhibitor Use With Incident Hypertension in Ankylosing Spondylitis: Data From the PSOAS Cohort.

The Journal of rheumatology

Liew JW, Jafarzadeh SR, Dubreuil M, Heckbert SR, Mooney SJ, Brown MA, Ishimori ML, Reveille JD, Ward MM, Weisman MH, Gensler LS.
PMID: 34853088
J Rheumatol. 2021 Dec 01; doi: 10.3899/jrheum.210332. Epub 2021 Dec 01.

OBJECTIVE: Individuals with ankylosing spondylitis (AS) have a greater cardiovascular (CV) risk than those in the general population. The effect of tumor necrosis factor inhibitors (TNFis) on CV risk, including on the development of hypertension (HTN), remains unclear, with...

Elevation of Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries.

medRxiv : the preprint server for health sciences

Qu HQ, Qu J, Dunn T, Snyder J, Miano TA, Connolly J, Glessner J, Anderson BJ, Reilly JP, Jones TK, Giannini HM, Agyekum RS, Weisman AR, Ittner CAG, Rodrigues LG, Kao C, Shashaty MGS, Sleiman P, Meyer NJ, Hakonarson H.
PMID: 34075388
medRxiv. 2021 May 27; doi: 10.1101/2021.05.25.21257799.

OBJECTIVE: The cytokines, LIGHT (TNFSF14) and Interleukin-18 (IL-18), are two important therapeutic targets due to their central roles in the function of activated T cells and inflammatory injury. LIGHT was recently shown to play a major role in COVID19...

Contraceptive Procedures in Internal Medicine Clinics and Resident Education: a Qualitative Study of Implementation Methods, Barriers, and Facilitators.

Journal of general internal medicine

Casas RS, Prifti CA, Bachorik AE, Stuckey H, Sobota M, Chuang CH, Weisman CS.
PMID: 33959883
J Gen Intern Med. 2021 Nov;36(11):3346-3352. doi: 10.1007/s11606-021-06832-3. Epub 2021 May 06.

BACKGROUND: Long-acting reversible contraceptives (LARCs) such as intrauterine devices (IUDs) and implants are highly effective and increasingly popular. Internal Medicine (IM) clinics and residency curricula do not routinely include LARCs, which can limit patient access to these methods. In...

Clinical Benefit within Patient Subgroups Receiving c7E3 Fab (Abciximab) During Percutaneous Coronary Revascularization: Subgroup Analysis from the EPIC Trial.

The Journal of invasive cardiology

Aguirre FV, Topol EJ, Anderson KM, Kleiman NS, Weisman HF, FitzPatrick SE, Califf RM.
PMID: 10785766
J Invasive Cardiol. 1996;8:21B-29B.

No abstract available.

THE SIMILARITY OF ACTION OF MALE HORMONES AND ADRENAL EXTRACTS ON THE FEMALE BITTERLING.

Science (New York, N.Y.)

Kleiner IS, Weisman AI, Mishkind DI.
PMID: 17755790
Science. 1937 Jan 15;85(2194):75. doi: 10.1126/science.85.2194.75.

No abstract available.

Phenylalanine: Transplacental centrations in Rhesus Monkeys.

Science (New York, N.Y.)

Kerr GR, Waisman HA.
PMID: 17746728
Science. 1966 Feb 18;151(3712):823-5. doi: 10.1126/science.151.3712.823.

Arbino acids are actively transported across the mammalian placenta, crncentrations in fetal blood being higher than those in the maternal circu-Elevated concentrations of phenylalanine were induced by dietarv means blood of pregnant rhesus monkeys, and the active transport mechanism...

Incidence of Ankylosing Spondylitis Among Male and Female United States Army Personnel.

Arthritis care & research

Nelson DA, Kaplan RM, Kurina LM, Weisman MH.
PMID: 34459565
Arthritis Care Res (Hoboken). 2021 Aug 30; doi: 10.1002/acr.24774. Epub 2021 Aug 30.

OBJECTIVE: Incidence rates of ankylosing spondylitis (AS) among males versus females are poorly understood. Results of prior research have been mixed, including findings of a 3:1 incidence ratio for males vs. females, but increasing AS rates among females.METHODS: We...

Evaluation of Diarylureas for Activity Against Plasmodium falciparum.

ACS medicinal chemistry letters

Zhang Y, Anderson M, Weisman JL, Lu M, Choy CJ, Boyd VA, Price J, Sigal M, Clark J, Connelly M, Zhu F, Guiguemde WA, Jeffries C, Yang L, Lemoff A, Liou AP, Webb TR, Derisi JL, Guy RK.
PMID: 21243104
ACS Med Chem Lett. 2010 Dec 09;1(9):460-465. doi: 10.1021/ml100083c.

A library of diarylurea IGFR inhibitors was screened for activity against chloroquine-sensitive (3D7) and chloroquine-resistant (K1) strains of Plasmodium falciparum. The 4-aminoquinaldine-derived diarylureas displayed promising antimalarial potency. Further exploration of the B ring of 4-aminoquinaldinyl ureas allowed identification of...

Showing 49 to 60 of 126 entries