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Showing 13 to 24 of 2845 entries
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Contributions of natural and anthropogenic radiative forcing to mass loss of Northern Hemisphere mountain glaciers and quantifying their uncertainties.

Scientific reports

Hirabayashi Y, Nakano K, Zhang Y, Watanabe S, Tanoue M, Kanae S.
PMID: 27435236
Sci Rep. 2016 Jul 20;6:29723. doi: 10.1038/srep29723.

Observational evidence indicates that a number of glaciers have lost mass in the past. Given that glaciers are highly impacted by the surrounding climate, human-influenced global warming may be partly responsible for mass loss. However, previous research studies have...

Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease.

Hepatology research : the official journal of the Japan Society of Hepatology

Fukushima H, Yamashina S, Arakawa A, Taniguchi G, Aoyama T, Uchiyama A, Kon K, Ikejima K, Watanabe S.
PMID: 29473277
Hepatol Res. 2018 Aug;48(9):757-767. doi: 10.1111/hepr.13071. Epub 2018 Apr 10.

AIM: Hepatic inclusion composed of autophagy-specific substrate p62 is one of the histological features of non-alcoholic fatty liver disease (NAFLD) and can be a precursor to hepatic carcinogenesis. The expression of p62 was enhanced by not only autophagic dysfunction...

Adaptive phenotypic variation among clonal ant workers.

Royal Society open science

Hasegawa E, Watanabe S, Murakami Y, Ito F.
PMID: 29515823
R Soc Open Sci. 2018 Feb 14;5(2):170816. doi: 10.1098/rsos.170816. eCollection 2018 Feb.

Phenotypic variations are observed in most organisms, but their significance is not always known. The phenotypic variations observed in social insects are exceptions. Genetically based response threshold variances have been identified among workers and are thought to play several...

Cleft Lip and Palate Repair Using a Surgical Microscope.

Archives of plastic surgery

Kato M, Watanabe A, Watanabe S, Utsunomiya H, Yokoyama T, Ogishima S.
PMID: 29069876
Arch Plast Surg. 2017 Nov;44(6):490-495. doi: 10.5999/aps.2017.01060. Epub 2017 Oct 26.

BACKGROUND: Cleft lip and palate repair requires a deep and small surgical field and is usually performed by surgeons wearing surgical loupes. Surgeons with loupes can obtain a wider surgical view, although headlights are required for the deepest procedures....

Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells.

Biology open

Maekawa M, Tanigawa K, Sakaue T, Hiyoshi H, Kubota E, Joh T, Watanabe Y, Taguchi T, Higashiyama S.
PMID: 29038302
Biol Open. 2017 Nov 15;6(11):1707-1719. doi: 10.1242/bio.029579.

Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is related to numerous pathophysiological events. We previously reported that a RING ubiquitin ligase complex scaffold protein, cullin-3 (CUL3), and one of its adaptor proteins, BAZF, regulated angiogenesis...

Antiemetic Effectiveness and Cost-Saving of Aprepitant plus Granisetron Is Superior to Palonosetron in Gastrointestinal Cancer Patients Who Received Moderately Emetogenic Chemotherapy.

Journal of Cancer

Toda H, Kawazoe H, Yano A, Yamamoto Y, Watanabe Y, Yamamoto Y, Hiasa Y, Yakushijin Y, Tanaka A, Araki H.
PMID: 28638451
J Cancer. 2017 May 12;8(8):1371-1377. doi: 10.7150/jca.17102. eCollection 2017.

No abstract available.

Atlantic hurricane surge response to geoengineering.

Proceedings of the National Academy of Sciences of the United States of America

Moore JC, Grinsted A, Guo X, Yu X, Jevrejeva S, Rinke A, Cui X, Kravitz B, Lenton A, Watanabe S, Ji D.
PMID: 26504210
Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13794-9. doi: 10.1073/pnas.1510530112. Epub 2015 Oct 26.

Devastating floods due to Atlantic hurricanes are relatively rare events. However, the frequency of the most intense storms is likely to increase with rises in sea surface temperatures. Geoengineering by stratospheric sulfate aerosol injection cools the tropics relative to...

Combined effects of recent Pacific cooling and Indian Ocean warming on the Asian monsoon.

Nature communications

Ueda H, Kamae Y, Hayasaki M, Kitoh A, Watanabe S, Miki Y, Kumai A.
PMID: 26564801
Nat Commun. 2015 Nov 13;6:8854. doi: 10.1038/ncomms9854.

Recent research indicates that the cooling trend in the tropical Pacific Ocean over the past 15 years underlies the contemporaneous hiatus in global mean temperature increase. During the hiatus, the tropical Pacific Ocean displays a La Niña-like cooling pattern...

Possible association of single nucleotide polymorphisms in the 3' untranslated region of HOXB9 with acetabular overcoverage.

Bone & joint research

Sekimoto T, Kurogi S, Funamoto T, Ota T, Watanabe S, Sakamoto T, Hamada H, Chosa E.
PMID: 25833894
Bone Joint Res. 2015 Apr;4(4):50-5. doi: 10.1302/2046-3758.44.2000349.

OBJECTIVES: Excessive acetabular coverage is the most common cause of pincer-type femoroacetabular impingement. To date, an association between acetabular over-coverage and genetic variations has not been studied. In this study we investigated the association between single nucleotide polymorphisms (SNPs)...

Association of a transcription factor 21 gene polymorphism with hypertension.

Biomedical reports

Fujimaki T, Oguri M, Horibe H, Kato K, Matsuoka R, Abe S, Tokoro F, Arai M, Noda T, Watanabe S, Yamada Y.
PMID: 25469260
Biomed Rep. 2015 Jan;3(1):118-122. doi: 10.3892/br.2014.371. Epub 2014 Oct 13.

Various loci and genes that confer susceptibility to coronary artery disease (CAD) have been identified mainly in Caucasian populations by genome-wide association studies (GWASs). As hypertension is a major risk factor for CAD, certain polymorphisms may contribute to the...

Normalization of Overexpressed α-Synuclein Causing Parkinson's Disease By a Moderate Gene Silencing With RNA Interference.

Molecular therapy. Nucleic acids

Takahashi M, Suzuki M, Fukuoka M, Fujikake N, Watanabe S, Murata M, Wada K, Nagai Y, Hohjoh H.
PMID: 25965551
Mol Ther Nucleic Acids. 2015 May 12;4:e241. doi: 10.1038/mtna.2015.14.

The α-synuclein (SNCA) gene is a responsible gene for Parkinson's disease (PD); and not only nucleotide variations but also overexpression of SNCA appears to be involved in the pathogenesis of PD. A specific inhibition against mutant SNCA genes carrying...

Successful control of a case of severe insulin allergy with liraglutide.

Journal of diabetes investigation

Kawanami D, Ito T, Watanabe Y, Kinoshita J, Sakamoto M, Isaka T, Utsunomiya K.
PMID: 24843637
J Diabetes Investig. 2013 Jan 29;4(1):94-6. doi: 10.1111/j.2040-1124.2012.00239.x. Epub 2012 Aug 30.

A 72-year-old woman presented with repeated hypoglycemic and hyperglycemic episodes because of an insulin allergy. On admission, she was diagnosed with type B insulin resistance syndrome. She was also found to have anti-insulin antibodies. After steroid therapy, glycemic control...

Showing 13 to 24 of 2845 entries