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Showing 8377 to 8387 of 8387 entries
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Vascular and Collagen Target: A Rational Approach to Hypertrophic Scar Management.

Advances in wound care

Yuan B, Upton Z, Leavesley D, Fan C, Wang XQ.
PMID: 34328823
Adv Wound Care (New Rochelle). 2021 Aug 10; doi: 10.1089/wound.2020.1348. Epub 2021 Aug 10.

No abstract available.

Active targeted Janus nanoparticles enable anti-angiogenic drug combining chemotherapy agent to prevent postoperative hepatocellular carcinoma recurrence.

Biomaterials

Zhang XP, Chen XJ, Li BZ, Xu S, Wu ZL, Hu MG, Zhao ZM, Zhao GD, Wang CR, Hong W, Li SP, Li L, Wang CG, Nie G, Liu R.
PMID: 34998170
Biomaterials. 2022 Jan 04;281:121362. doi: 10.1016/j.biomaterials.2022.121362. Epub 2022 Jan 04.

Surgery is one of the main effective strategies for the treatment of solid tumors, but high postoperative recurrence is also the main cause of death in current cancer therapy. The prevention of postoperative hepatocellular carcinoma (HCC) recurrence is a...

Mendelian Randomization Analysis Reveals Causal Effects of the Human Gut Microbiota on Abdominal Obesity.

The Journal of nutrition

Xu Q, Zhang SS, Wang RR, Weng YJ, Cui X, Wei XT, Ni JJ, Ren HG, Zhang L, Pei YF.
PMID: 33768223
J Nutr. 2021 Jun 01;151(6):1401-1406. doi: 10.1093/jn/nxab025.

BACKGROUND: Although recent studies have revealed an association between the composition of the gut microbiota and obesity, whether specific gut microbiota cause obesity has not been determined.OBJECTIVES: The aim of this study is to determine the causal relationship between...

The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway.

Frontiers in pharmacology

Chen L, Guo Y, Qu S, Li K, Yang T, Yang Y, Zheng Z, Liu H, Wang X, Deng S, Zhang Y, Zhu X, Li Y.
PMID: 33762941
Front Pharmacol. 2021 Mar 08;12:619311. doi: 10.3389/fphar.2021.619311. eCollection 2021.

No abstract available.

Hepatoprotective effects of chamazulene against alcohol-induced liver damage by alleviation of oxidative stress in rat models.

Open life sciences

Wang X, Dong K, Ma Y, Jin Q, Yin S, Wang S.
PMID: 33817213
Open Life Sci. 2020 Apr 20;15(1):251-258. doi: 10.1515/biol-2020-0026. eCollection 2020.

Liver injury and disease caused by alcohol is a common complication to human health worldwide. Chamazulene is a natural proazulene with antioxidant and anti-inflammatory properties. This study aims to investigate the hepatoprotective effects of chamazulene against ethanol-induced liver injury...

Association of HIF-1α and NDRG2 Expression with EMT in Gastric Cancer Tissues.

Open life sciences

Wang RX, Ou XW, Kang MF, Zhou ZP.
PMID: 33817155
Open Life Sci. 2019 Jul 22;14:217-223. doi: 10.1515/biol-2019-0025. eCollection 2019 Jan.

OBJECTIVE: This study aims to investigate the differences in the expression of hypoxia-inducible factor-1α (HIF-1α), N-myc downstream-regulated gene 2 (NDRG2) and epithelial mesenchymal transition (EMT)-related proteins in normal gastric tissues, gastric cancer tissues and lymph node metastasis.METHODS: Immunohistochemistry was...

Serum tumor markers for the prediction of concordance between genomic profiles from liquid and tissue biopsy in patients with advanced lung adenocarcinoma.

Translational lung cancer research

Jiao XD, Ding LR, Zhang CT, Qin BD, Liu K, Jiang LP, Wang X, Lv LT, Ding H, Li DM, Yang H, Chen XQ, Zhu WY, Wu Y, Ling Y, He X, Liu J, Shao L, Wang HZ, Chen Y, Zheng JJ, Inui N, Zang YS.
PMID: 34430361
Transl Lung Cancer Res. 2021 Jul;10(7):3236-3250. doi: 10.21037/tlcr-21-543.

BACKGROUND: The concordance between mutations detected from plasma and tissue is critical for treatment choices of patients with advanced lung adenocarcinoma.METHODS: We prospectively analyzed the association of the serum tumor markers with the concordance between blood and tissue genomic...

Identification of NLRP3 as a covalent target of 1,6-O,O-diacetylbritannilactone against neuroinflammation by quantitative thiol reactivity profiling (QTRP).

Bioorganic chemistry

Wang MR, Huang LF, Guo C, Yang J, Dong S, Tang JJ, Gao JM.
PMID: 34894577
Bioorg Chem. 2021 Dec 05;119:105536. doi: 10.1016/j.bioorg.2021.105536. Epub 2021 Dec 05.

Neuroinflammation plays a key etiological role in the progressive neuronal damage of neurodegenerative diseases. Our phenotypic-based screening discovered 1,6-O,O-diacetylbritannilactone (OABL, 1) from Inula britannica exhibited the potential anti-neuroinflammatory activity as well as a favorable blood-brain barrier penetration. 1 and...

Machine Learning: New Ideas and Tools in Environmental Science and Engineering.

Environmental science & technology

Zhong S, Zhang K, Bagheri M, Burken JG, Gu A, Li B, Ma X, Marrone BL, Ren ZJ, Schrier J, Shi W, Tan H, Wang T, Wang X, Wong BM, Xiao X, Yu X, Zhu JJ, Zhang H.
PMID: 34403250
Environ Sci Technol. 2021 Oct 05;55(19):12741-12754. doi: 10.1021/acs.est.1c01339. Epub 2021 Aug 17.

The rapid increase in both the quantity and complexity of data that are being generated daily in the field of environmental science and engineering (ESE) demands accompanied advancement in data analytics. Advanced data analysis approaches, such as machine learning...

Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative.

ACS applied bio materials

Luo YL, Rong RX, Li JM, Chen X, Wang SS, Li XL, Wang KR.
PMID: 35025381
ACS Appl Bio Mater. 2020 May 18;3(5):3390-3400. doi: 10.1021/acsabm.0c00311. Epub 2020 May 06.

Metabolic clearance of drugs from the body is a key element for future clinical applications. Compared with the liver-bile metabolic route, the renal-urinary route is the most desirable and efficient clearance pathway for practical use in clinical trials and...

Why Students Choose STEM Majors: Motivation, High School Learning, and Postsecondary Context of Support.

Wang XL.
UIID-AD: 1226
2013;50:1081-1121. doi: 10.3102/0002831213488622.

This study draws upon social cognitive career theory and higher education literature to test a conceptual framework for understanding the entrance into science, technology, engineering, and mathematics (STEM) majors by recent high school graduates attending 4-year institutions. Results suggest...

Showing 8377 to 8387 of 8387 entries