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Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.

Frontiers in cell and developmental biology

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F.
PMID: 33681191
Front Cell Dev Biol. 2021 Feb 11;9:581805. doi: 10.3389/fcell.2021.581805. eCollection 2021.

Cathepsin D (CTSD) is a lysosomal protease important for the degradation of various substrates, including disease-associated proteins like α-synuclein (a-syn), amyloid precursor protein (APP) and tau, all of which tend to aggregate if not efficiently degraded. Hence, it is...

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Bunk J, Prieto Huarcaya S, Drobny A, et al. Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties. Front Cell Dev Biol. 2021;9:581805doi: 10.3389/fcell.2021.581805.
Bunk, J., Prieto Huarcaya, S., Drobny, A., Dobert, J. P., Walther, L., Rose-John, S., Arnold, P., & Zunke, F. (2021). Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties. Frontiers in cell and developmental biology, 9581805. https://doi.org/10.3389/fcell.2021.581805
Bunk, Josina, et al. "Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties." Frontiers in cell and developmental biology vol. 9 (2021): 581805. doi: https://doi.org/10.3389/fcell.2021.581805
Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F. Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties. Front Cell Dev Biol. 2021 Feb 11;9:581805. doi: 10.3389/fcell.2021.581805. eCollection 2021. PMID: 33681191; PMCID: PMC7928348.
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[The role of university hospitals in regional health care management for coping with the COVID-19 pandemic].

Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

Panchyrz I, Pohl S, Hoffmann J, Gatermann C, Walther F, Harst L, Held HC, Kleber C, Albrecht M, Schmitt J.
PMID: 34774428
Z Evid Fortbild Qual Gesundhwes. 2021 Dec;167:68-77. doi: 10.1016/j.zefq.2021.09.004. Epub 2021 Nov 10.

INTRODUCTION: The complex and dynamic situation in the current pandemic requires a regionally coordinated and interconnected cooperation between the different stakeholders within the health care system, such as the inpatient sector or the public health service. The aim of...

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Panchyrz I, Pohl S, Hoffmann J, et al. Die Rolle der Universitätskliniken im regionalen medizinischen Versorgungsmanagement zur Bewältigung der COVID-19 Pandemie. [The role of university hospitals in regional health care management for coping with the COVID-19 pandemic]. Z Evid Fortbild Qual Gesundhwes. 2021;167:68-77doi: 10.1016/j.zefq.2021.09.004.
Panchyrz, I., Pohl, S., Hoffmann, J., Gatermann, C., Walther, F., Harst, L., Held, H. C., Kleber, C., Albrecht, M., & Schmitt, J. (2021). Die Rolle der Universitätskliniken im regionalen medizinischen Versorgungsmanagement zur Bewältigung der COVID-19 Pandemie. [The role of university hospitals in regional health care management for coping with the COVID-19 pandemic]. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, 16768-77. https://doi.org/10.1016/j.zefq.2021.09.004
Panchyrz, Ivonne, et al. "Die Rolle der Universitätskliniken im regionalen medizinischen Versorgungsmanagement zur Bewältigung der COVID-19 Pandemie." [The role of university hospitals in regional health care management for coping with the COVID-19 pandemic]. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen vol. 167 (2021): 68-77. doi: https://doi.org/10.1016/j.zefq.2021.09.004
Panchyrz I, Pohl S, Hoffmann J, Gatermann C, Walther F, Harst L, Held HC, Kleber C, Albrecht M, Schmitt J. Die Rolle der Universitätskliniken im regionalen medizinischen Versorgungsmanagement zur Bewältigung der COVID-19 Pandemie. [The role of university hospitals in regional health care management for coping with the COVID-19 pandemic]. Z Evid Fortbild Qual Gesundhwes. 2021 Dec;167:68-77. doi: 10.1016/j.zefq.2021.09.004. Epub 2021 Nov 10. German. PMID: 34774428; PMCID: PMC8580327.
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Physico-chemical analysis of electrospun fibers - A systematic approach.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Walther M, Rohde F, Kielholz T, Windbergs M.
PMID: 35007695
Eur J Pharm Biopharm. 2022 Jan 07; doi: 10.1016/j.ejpb.2022.01.001. Epub 2022 Jan 07.

Electrospun fibers emerged as promising drug delivery systems for various pharmaceutical applications due to their favorable properties. However, while for established drug delivery systems (e.g. tablets or capsules) standardized analytical procedures exist, the methodologies for characterization of electrospun fibers...

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Walther M, Rohde F, Kielholz T, et al. Physico-chemical analysis of electrospun fibers - A systematic approach. Eur J Pharm Biopharm. 2022;doi: 10.1016/j.ejpb.2022.01.001.
Walther, M., Rohde, F., Kielholz, T., & Windbergs, M. (2022). Physico-chemical analysis of electrospun fibers - A systematic approach. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, . https://doi.org/10.1016/j.ejpb.2022.01.001
Walther, M, et al. "Physico-chemical analysis of electrospun fibers - A systematic approach." European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V vol. (2022). doi: https://doi.org/10.1016/j.ejpb.2022.01.001
Walther M, Rohde F, Kielholz T, Windbergs M. Physico-chemical analysis of electrospun fibers - A systematic approach. Eur J Pharm Biopharm. 2022 Jan 07; doi: 10.1016/j.ejpb.2022.01.001. Epub 2022 Jan 07. PMID: 35007695.
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Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain.

Heliyon

Hami J, von Bohlen Und Halbach V, Tetzner A, Walther T, von Bohlen Und Halbach O.
PMID: 34901497
Heliyon. 2021 Nov 18;7(11):e08440. doi: 10.1016/j.heliyon.2021.e08440. eCollection 2021 Nov.

Numerous studies in the last decades have provided evidence for the existence of a local renin-angiotensin system (RAS) in the central nervous system (CNS). Widespread distribution of the different RAS components in the brain demonstrates the pleiotropic role of...

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Hami J, von Bohlen Und Halbach V, Tetzner A, et al. Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain. Heliyon. 2021;7(11):e08440doi: 10.1016/j.heliyon.2021.e08440.
Hami, J., von Bohlen Und Halbach, V., Tetzner, A., Walther, T., & von Bohlen Und Halbach, O. (2021). Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain. Heliyon, 7(11), e08440. https://doi.org/10.1016/j.heliyon.2021.e08440
Hami, Javad, et al. "Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain." Heliyon vol. 7,11 (2021): e08440. doi: https://doi.org/10.1016/j.heliyon.2021.e08440
Hami J, von Bohlen Und Halbach V, Tetzner A, Walther T, von Bohlen Und Halbach O. Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain. Heliyon. 2021 Nov 18;7(11):e08440. doi: 10.1016/j.heliyon.2021.e08440. eCollection 2021 Nov. PMID: 34901497; PMCID: PMC8637488.
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Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia.

Schizophrenia bulletin

Viher PV, Stegmayer K, Bracht T, Federspiel A, Bohlhalter S, Strik W, Wiest R, Walther S.
PMID: 34355246
Schizophr Bull. 2021 Aug 06; doi: 10.1093/schbul/sbab089. Epub 2021 Aug 06.

Neurological soft signs (NSS) are related to grey matter and functional brain abnormalities in schizophrenia. Studies in healthy subjects suggest, that NSS are also linked to white matter. However, the association between NSS and white matter abnormalities in schizophrenia...

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Viher PV, Stegmayer K, Bracht T, et al. Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia. Schizophr Bull. 2021;doi: 10.1093/schbul/sbab089.
Viher, P. V., Stegmayer, K., Bracht, T., Federspiel, A., Bohlhalter, S., Strik, W., Wiest, R., & Walther, S. (2021). Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia. Schizophrenia bulletin, . https://doi.org/10.1093/schbul/sbab089
Viher, Petra Verena, et al. "Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia." Schizophrenia bulletin vol. (2021). doi: https://doi.org/10.1093/schbul/sbab089
Viher PV, Stegmayer K, Bracht T, Federspiel A, Bohlhalter S, Strik W, Wiest R, Walther S. Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia. Schizophr Bull. 2021 Aug 06; doi: 10.1093/schbul/sbab089. Epub 2021 Aug 06. PMID: 34355246.
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One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve.

Circulation

Kim WK, Walther T, Burgdorf C, Möllmann H, Linke A, Redwood S, Thilo C, Hilker M, Joner M, Thiele H, Conzelmann L, Conradi L, Kerber S, Schymik G, Prendergast B, Husser O, Blumenstein J, Stortecky S, Heg D, Künzi A, Jüni P, Windecker S, Pilgrim T, Lanz J.
PMID: 33750210
Circulation. 2021 Mar 23;143(12):1267-1269. doi: 10.1161/CIRCULATIONAHA.120.052251. Epub 2021 Mar 22.

No abstract available.

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Kim WK, Walther T, Burgdorf C, et al. One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve. Circulation. 2021;143(12):1267-1269doi: 10.1161/CIRCULATIONAHA.120.052251.
Kim, W. K., Walther, T., Burgdorf, C., Möllmann, H., Linke, A., Redwood, S., Thilo, C., Hilker, M., Joner, M., Thiele, H., Conzelmann, L., Conradi, L., Kerber, S., Schymik, G., Prendergast, B., Husser, O., Blumenstein, J., Stortecky, S., Heg, D., Künzi, A., Jüni, P., Windecker, S., Pilgrim, T., Lanz, J. (2021). One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve. Circulation, 143(12), 1267-1269. https://doi.org/10.1161/CIRCULATIONAHA.120.052251
Kim, Won-Keun, et al. "One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve." Circulation vol. 143,12 (2021): 1267-1269. doi: https://doi.org/10.1161/CIRCULATIONAHA.120.052251
Kim WK, Walther T, Burgdorf C, Möllmann H, Linke A, Redwood S, Thilo C, Hilker M, Joner M, Thiele H, Conzelmann L, Conradi L, Kerber S, Schymik G, Prendergast B, Husser O, Blumenstein J, Stortecky S, Heg D, Künzi A, Jüni P, Windecker S, Pilgrim T, Lanz J. One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve. Circulation. 2021 Mar 23;143(12):1267-1269. doi: 10.1161/CIRCULATIONAHA.120.052251. Epub 2021 Mar 22. PMID: 33750210.
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Fiber-compatible photonic feed-forward with 99% fidelity.

Optics express

Luiz Zanin G, Jacquet MJ, Spagnolo M, Schiansky P, Calafell IA, Rozema LA, Walther P.
PMID: 33770941
Opt Express. 2021 Feb 01;29(3):3425-3437. doi: 10.1364/OE.409867.

Both photonic quantum computation and the establishment of a quantum internet require fiber-based measurement and feed-forward in order to be compatible with existing infrastructure. Here we present a fiber-compatible scheme for measurement and feed-forward, whose performance is benchmarked by...

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Luiz Zanin G, Jacquet MJ, Spagnolo M, et al. Fiber-compatible photonic feed-forward with 99% fidelity. Opt Express. 2021;29(3):3425-3437doi: 10.1364/OE.409867.
Luiz Zanin, G., Jacquet, M. J., Spagnolo, M., Schiansky, P., Calafell, I. A., Rozema, L. A., & Walther, P. (2021). Fiber-compatible photonic feed-forward with 99% fidelity. Optics express, 29(3), 3425-3437. https://doi.org/10.1364/OE.409867
Luiz Zanin, Guilherme, et al. "Fiber-compatible photonic feed-forward with 99% fidelity." Optics express vol. 29,3 (2021): 3425-3437. doi: https://doi.org/10.1364/OE.409867
Luiz Zanin G, Jacquet MJ, Spagnolo M, Schiansky P, Calafell IA, Rozema LA, Walther P. Fiber-compatible photonic feed-forward with 99% fidelity. Opt Express. 2021 Feb 01;29(3):3425-3437. doi: 10.1364/OE.409867. PMID: 33770941.
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[No title available]

Atencion primaria

Diez JD, Caicedo LM, Rodríguez PR, Morales MC, Maestu LP, Walther LA.
PMID: 22397829
Aten Primaria. 2012 Mar 06; doi: 10.1016/j.aprim.2012.01.002. Epub 2012 Mar 06.

No abstract available.

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Diez JD, Caicedo LM, Rodríguez PR, et al. WITHDRAWN: La enfermedad pulmonar obstructiva crónica como factor de riesgo cardiovascular. . Aten Primaria. 2012;doi: 10.1016/j.aprim.2012.01.002.
Diez, J. D., Caicedo, L. M., Rodríguez, P. R., Morales, M. C., Maestu, L. P., & Walther, L. A. (2012). WITHDRAWN: La enfermedad pulmonar obstructiva crónica como factor de riesgo cardiovascular. . Atencion primaria, . https://doi.org/10.1016/j.aprim.2012.01.002
Diez, Javier de Miguel, et al. "WITHDRAWN: La enfermedad pulmonar obstructiva crónica como factor de riesgo cardiovascular." . Atencion primaria vol. (2012). doi: https://doi.org/10.1016/j.aprim.2012.01.002
Diez JD, Caicedo LM, Rodríguez PR, Morales MC, Maestu LP, Walther LA. WITHDRAWN: La enfermedad pulmonar obstructiva crónica como factor de riesgo cardiovascular. . Aten Primaria. 2012 Mar 06; doi: 10.1016/j.aprim.2012.01.002. Epub 2012 Mar 06. Spanish. PMID: 22397829.
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Correction to: Cross-Modality Imaging of Murine Tumor Vasculature-a Feasibility Study.

Molecular imaging and biology

Zopf LM, Heimel P, Geyer SH, Kavirayani A, Reier S, Fröhlich V, Stiglbauer-Tscholakoff A, Chen Z, Nics L, Zinnanti J, Drexler W, Mitterhauser M, Helbich T, Weninger WJ, Slezak P, Obenauf A, Bühler K, Walter A.
PMID: 34302268
Mol Imaging Biol. 2021 Dec;23(6):894. doi: 10.1007/s11307-021-01625-w.

No abstract available.

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Zopf LM, Heimel P, Geyer SH, et al. Correction to: Cross-Modality Imaging of Murine Tumor Vasculature-a Feasibility Study. Mol Imaging Biol. 2021;23(6):894doi: 10.1007/s11307-021-01625-w.
Zopf, L. M., Heimel, P., Geyer, S. H., Kavirayani, A., Reier, S., Fröhlich, V., Stiglbauer-Tscholakoff, A., Chen, Z., Nics, L., Zinnanti, J., Drexler, W., Mitterhauser, M., Helbich, T., Weninger, W. J., Slezak, P., Obenauf, A., Bühler, K., & Walter, A. (2021). Correction to: Cross-Modality Imaging of Murine Tumor Vasculature-a Feasibility Study. Molecular imaging and biology, 23(6), 894. https://doi.org/10.1007/s11307-021-01625-w
Zopf, Lydia M, et al. "Correction to: Cross-Modality Imaging of Murine Tumor Vasculature-a Feasibility Study." Molecular imaging and biology vol. 23,6 (2021): 894. doi: https://doi.org/10.1007/s11307-021-01625-w
Zopf LM, Heimel P, Geyer SH, Kavirayani A, Reier S, Fröhlich V, Stiglbauer-Tscholakoff A, Chen Z, Nics L, Zinnanti J, Drexler W, Mitterhauser M, Helbich T, Weninger WJ, Slezak P, Obenauf A, Bühler K, Walter A. Correction to: Cross-Modality Imaging of Murine Tumor Vasculature-a Feasibility Study. Mol Imaging Biol. 2021 Dec;23(6):894. doi: 10.1007/s11307-021-01625-w. PMID: 34302268.
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Prenatal detection of a giant isolated coronary fistula.

Clinical case reports

Walter A, Calite E, Engels AC, Herberg U, Breuer J, Willruth A, Berg C, Geipel A, Gembruch U.
PMID: 33768852
Clin Case Rep. 2021 Feb 04;9(3):1393-1396. doi: 10.1002/ccr3.3779. eCollection 2021 Mar.

Prenatal detection of an isolated congenital coronary artery fistula (ICCAF) requires an examination of the affected fetal hemodynamic situation by the fistula. Early pediatric cardiological presentation is needed, since prenatal changes may have relevant postpartal consequences.

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Walter A, Calite E, Engels AC, et al. Prenatal detection of a giant isolated coronary fistula. Clin Case Rep. 2021;9(3):1393-1396doi: 10.1002/ccr3.3779.
Walter, A., Calite, E., Engels, A. C., Herberg, U., Breuer, J., Willruth, A., Berg, C., Geipel, A., & Gembruch, U. (2021). Prenatal detection of a giant isolated coronary fistula. Clinical case reports, 9(3), 1393-1396. https://doi.org/10.1002/ccr3.3779
Walter, Adeline, et al. "Prenatal detection of a giant isolated coronary fistula." Clinical case reports vol. 9,3 (2021): 1393-1396. doi: https://doi.org/10.1002/ccr3.3779
Walter A, Calite E, Engels AC, Herberg U, Breuer J, Willruth A, Berg C, Geipel A, Gembruch U. Prenatal detection of a giant isolated coronary fistula. Clin Case Rep. 2021 Feb 04;9(3):1393-1396. doi: 10.1002/ccr3.3779. eCollection 2021 Mar. PMID: 33768852; PMCID: PMC7981625.
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Wavelength-Selective Softening of Hydrogel Networks.

Advanced materials (Deerfield Beach, Fla.)

Pelloth JL, Tran PA, Walther A, Goldmann AS, Frisch H, Truong VX, Barner-Kowollik C.
PMID: 34365684
Adv Mater. 2021 Oct;33(39):e2102184. doi: 10.1002/adma.202102184. Epub 2021 Aug 08.

Photoresponsive hydrogels hold key potential in advanced biomedical applications including tissue engineering, regenerative medicine, and drug delivery, as well as intricately engineered functions such as biosensing, soft robotics, and bioelectronics. Herein, the wavelength-dependent degradation of bio-orthogonal poly(ethylene glycol) hydrogels...

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Pelloth JL, Tran PA, Walther A, et al. Wavelength-Selective Softening of Hydrogel Networks. Adv Mater. 2021;33(39):e2102184doi: 10.1002/adma.202102184.
Pelloth, J. L., Tran, P. A., Walther, A., Goldmann, A. S., Frisch, H., Truong, V. X., & Barner-Kowollik, C. (2021). Wavelength-Selective Softening of Hydrogel Networks. Advanced materials (Deerfield Beach, Fla.), 33(39), e2102184. https://doi.org/10.1002/adma.202102184
Pelloth, Jessica L, et al. "Wavelength-Selective Softening of Hydrogel Networks." Advanced materials (Deerfield Beach, Fla.) vol. 33,39 (2021): e2102184. doi: https://doi.org/10.1002/adma.202102184
Pelloth JL, Tran PA, Walther A, Goldmann AS, Frisch H, Truong VX, Barner-Kowollik C. Wavelength-Selective Softening of Hydrogel Networks. Adv Mater. 2021 Oct;33(39):e2102184. doi: 10.1002/adma.202102184. Epub 2021 Aug 08. PMID: 34365684.
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Letter to the editor.

Critical care (London, England)

Sjöberg F, Orwelius L, Chew M, Berg S, Walther S.
PMID: 34284803
Crit Care. 2021 Jul 20;25(1):255. doi: 10.1186/s13054-021-03635-0.

No abstract available.

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Sjöberg F, Orwelius L, Chew M, et al. Letter to the editor. Crit Care. 2021;25(1):255doi: 10.1186/s13054-021-03635-0.
Sjöberg, F., Orwelius, L., Chew, M., Berg, S., & Walther, S. (2021). Letter to the editor. Critical care (London, England), 25(1), 255. https://doi.org/10.1186/s13054-021-03635-0
Sjöberg, Folke, et al. "Letter to the editor." Critical care (London, England) vol. 25,1 (2021): 255. doi: https://doi.org/10.1186/s13054-021-03635-0
Sjöberg F, Orwelius L, Chew M, Berg S, Walther S. Letter to the editor. Crit Care. 2021 Jul 20;25(1):255. doi: 10.1186/s13054-021-03635-0. PMID: 34284803; PMCID: PMC8290535.
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Showing 1357 to 1368 of 1379 entries