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Showing 253 to 258 of 258 entries
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Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ.

Nucleic acids research

Dahl JM, Thomas N, Tracy MA, Hearn BL, Perera L, Kennedy SR, Herr AJ, Kunkel TA.
PMID: 35037018
Nucleic Acids Res. 2022 Jan 17; doi: 10.1093/nar/gkab1255. Epub 2022 Jan 17.

We report the properties of two mutations in the exonuclease domain of the Saccharomyces cerevisiae DNA polymerase ϵ. One, pol2-Y473F, increases the mutation rate by about 20-fold, similar to the catalytically dead pol2-D290A/E290A mutant. The other, pol2-N378K, is a...

Societal implications of a changing Arctic Ocean.

Ambio

Huntington HP, Zagorsky A, Kaltenborn BP, Shin HC, Dawson J, Lukin M, Dahl PE, Guo P, Thomas DN.
PMID: 34279810
Ambio. 2022 Feb;51(2):298-306. doi: 10.1007/s13280-021-01601-2. Epub 2021 Jul 19.

The Arctic Ocean is undergoing rapid change: sea ice is being lost, waters are warming, coastlines are eroding, species are moving into new areas, and more. This paper explores the many ways that a changing Arctic Ocean affects societies...

Assessing the use of ellipsoidal microparticles for determining lipid membrane viscosity.

Biophysical journal

Jahl PE, Parthasarathy R.
PMID: 34800470
Biophys J. 2021 Nov 18; doi: 10.1016/j.bpj.2021.11.020. Epub 2021 Nov 18.

The viscosity of lipid membranes sets the timescales of membrane-associated motions, whether driven or diffusive, and therefore influences the dynamics of a wide range of cellular processes. Techniques to measure membrane viscosity remain sparse, however, and reported measurements to...

No Evidence of the Vertical Transmission of Non-Virulent Infectious Salmon Anaemia Virus (ISAV-HPR0) in Farmed Atlantic Salmon.

Viruses

Christiansen DH, Petersen PE, Dahl MM, Vest N, Aamelfot M, Kristoffersen AB, Jansen MD, Matejusova I, Gallagher MD, Jónsson G, Rodriguez E, Fosse JH, Falk K.
PMID: 34960697
Viruses. 2021 Dec 03;13(12). doi: 10.3390/v13122428.

The nonvirulent infectious salmon anaemia virus (ISAV-HPR0) is the putative progenitor for virulent-ISAV, and a potential risk factor for the development of infectious salmon anaemia (ISA). Understanding the transmission dynamics of ISAV-HPR0 is fundamental to proper management and mitigation...

Analysis of the Mercury Distribution in Blood as a Potential Tool for Exposure Assessment - Results from Two Artisanal and Small-Scale Gold Mining Areas in Zimbabwe.

Biological trace element research

Wahl AM, Bose-O'Reilly S, Mambrey V, Rooney JPK, Shoko D, Moyo D, Muteti-Fana S, Steckling-Muschack N, Rakete S.
PMID: 33893622
Biol Trace Elem Res. 2021 Apr 23; doi: 10.1007/s12011-021-02714-1. Epub 2021 Apr 23.

People in artisanal and small-scale gold mining (ASGM) areas are frequently exposed to high levels of mercury (Hg). Hg analyses in urine and whole blood are the gold standard of biomonitoring, although this may not provide sufficient information about...

Expression of .

Cancers

Müller CSL, Pföhler C, Wahl M, Bochen F, Körner S, Kühn JP, Bozzato A, Schick B, Linxweiler M.
PMID: 33915997
Cancers (Basel). 2021 Apr 01;13(7). doi: 10.3390/cancers13071645.

No abstract available.

Showing 253 to 258 of 258 entries