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Showing 1501 to 1511 of 1511 entries
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The Impact of Tumor Mutation Burden on the Effect of Frontline Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2-Positive Advanced Gastric Cancers.

Frontiers in oncology

Kim HR, Ahn S, Jo H, Kim H, Hong J, Lee J, Lim HY, Kang WK, Kim ST.
PMID: 34926309
Front Oncol. 2021 Dec 02;11:792340. doi: 10.3389/fonc.2021.792340. eCollection 2021.

BACKGROUND: Trastuzumab is a HER2-trargeted humanized monoclonal antibody that has been studied as a first-line treatment for patients with HER2-positive advanced gastric cancer (AGC). The effect of anti-HER2 therapy according to tumor mutational burden (TMB) in HER2-positive AGC remains...

The Art of Framework Construction: Core-Shell Structured Micro-Energetic Materials.

Molecules (Basel, Switzerland)

Duan B, Li J, Mo H, Lu X, Xu M, Wang B, Liu N.
PMID: 34577119
Molecules. 2021 Sep 17;26(18). doi: 10.3390/molecules26185650.

Weak interfacial interactions remain a bottleneck for composite materials due to their weakened performance and restricted applications. The development of core-shell engineering shed light on the preparation of compact and intact composites with improved interfacial interactions. This review addresses...

Hemodynamic effects of carbetocin administered as an intravenous bolus or infusion during cesarean delivery.

Anesthesia and pain medicine

Kwon K, Kim D, Jo H, Park JE, Kim KO.
PMID: 33329809
Anesth Pain Med (Seoul). 2020 Apr 30;15(2):167-172. doi: 10.17085/apm.2020.15.2.167. Epub 2020 Apr 29.

BACKGROUND: Postpartum hemorrhage is the leading cause of maternal mortality. Oxytocin being the most popular uterotonic agent, has been routinely administered after both vaginal delivery and cesarean section. Carbetocin is a newer uterotonic agent and provides the benefit of...

The combination of intermittent electrical stimulation with acute intermittent hypoxia strengthens genioglossus muscle discharge in chronic intermittent hypoxia-pretreated rats.

Respiratory physiology & neurobiology

Mo H, Zhao J, Wu X, Liu W, Hu K.
PMID: 33971311
Respir Physiol Neurobiol. 2021 Sep;291:103680. doi: 10.1016/j.resp.2021.103680. Epub 2021 May 07.

OBJECTIVE: Exploring whether the genioglossus discharge in chronic intermittent hypoxia(CIH) - pretreated rats could be enhanced by intermittent electrical stimulation combined with acute intermittent hypoxia(AIH).METHODS: Rats were pretreated with CIH for 4 weeks and then were randomly divided into...

Long Noncoding RNA RP11-115N4.1 Promotes Inflammatory Responses by Interacting With HNRNPH3 and Enhancing the Transcription of HSP70 in Unexplained Recurrent Spontaneous Abortion.

Frontiers in immunology

Liu M, Sun X, Zhu L, Zhu M, Deng K, Nie X, Mo H, Du T, Huang B, Hu L, Liang L, Wang D, Luo Y, Yi J, Zhang J, Zhong X, Cao C, Chen H.
PMID: 34484222
Front Immunol. 2021 Aug 13;12:717785. doi: 10.3389/fimmu.2021.717785. eCollection 2021.

BACKGROUND: Unexplained recurrent spontaneous abortion (URSA) is a common pregnancy complication and the etiology is unknown. URSA-associated lncRNAs are expected to be potential biomarkers for diagnosis, and might be related to the disease pathogenesis.OBJECTIVE: To investigate differential lncRNAs in...

Rapid detection of neutralizing antibodies to SARS-CoV-2 variants in post-vaccination sera.

Journal of molecular cell biology

Miyakawa K, Stanleyraj JS, Kato H, Yamaoka Y, Go H, Yajima S, Shimada T, Mihara T, Goto A, Yamanaka T, Ryo A.
PMID: 34450642
J Mol Cell Biol. 2021 Aug 27; doi: 10.1093/jmcb/mjab050. Epub 2021 Aug 27.

The uncontrolled spread of the COVID-19 pandemic has led to the emergence of different SARS-CoV-2 variants across the globe. The ongoing global vaccination strategy to curtail the COVID-19 juggernaut, is threatened by the rapidly spreading Variants of Concern (VOC)...

Clinical Characteristics and Fracture Patterns Among Postmenopausal Women with Isolated Osteoporosis at the Forearm.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Chukir T, Haseltine K, Do H, McMahon DJ, Russell L, Stein EM.
PMID: 34511326
J Clin Densitom. 2021 Aug 13; doi: 10.1016/j.jocd.2021.07.012. Epub 2021 Aug 13.

Patients found to have isolated osteoporosis at the 1/3 radius (1/3RO) represent a therapeutic dilemma. It is unknown whether 1/3RO is associated with an increased risk of fragility fractures, and is therefore unclear whether these patients should be treated...

Pneumothorax and Pneumomediastinum Secondary to COVID-19 Disease Unrelated to Mechanical Ventilation.

Case reports in critical care

Tucker L, Patel S, Vatsis C, Poma A, Ammar A, Nasser W, Mukkera S, Vo M, Khan R, Carlan S.
PMID: 33299613
Case Rep Crit Care. 2020 Nov 23;2020:6655428. doi: 10.1155/2020/6655428. eCollection 2020.

In the recent worldwide coronavirus 2019 pandemic, a notable rise in pneumomediastinum and pneumothorax complications has been witnessed in numerous mechanically ventilated patients infected with severe acute respiratory syndrome coronavirus 2. Most cases have reported these complications as barotrauma...

Global warming-induced Asian hydrological climate transition across the Miocene-Pliocene boundary.

Nature communications

Ao H, Rohling EJ, Zhang R, Roberts AP, Holbourn AE, Ladant JB, Dupont-Nivet G, Kuhnt W, Zhang P, Wu F, Dekkers MJ, Liu Q, Liu Z, Xu Y, Poulsen CJ, Licht A, Sun Q, Chiang JCH, Liu X, Wu G, Ma C, Zhou W, Jin Z, Li X, Li X, Peng X, Qiang X, An Z.
PMID: 34836960
Nat Commun. 2021 Nov 26;12(1):6935. doi: 10.1038/s41467-021-27054-5.

Across the Miocene-Pliocene boundary (MPB; 5.3 million years ago, Ma), late Miocene cooling gave way to the early-to-middle Pliocene Warm Period. This transition, across which atmospheric CO

Overexpression of SKA3 correlates with poor prognosis in female early breast cancer.

PeerJ

Zhong Y, Zhuang Z, Mo P, Lin M, Gong J, Huang J, Mo H, Lu Y, Huang M.
PMID: 34993016
PeerJ. 2021 Dec 13;9:e12506. doi: 10.7717/peerj.12506. eCollection 2021.

BACKGROUND: Spindle and kinetochore associated complex subunit 3 (SKA3) plays an important role in tumorigenesis and the progression of various tumors. But the relationship between SKA3 and early breast cancer remains unclear. The study aimed to explore the prognostic...

Confined electrochemiluminescence imaging microarray for high-throughput biosensing of single cell-released dopamine.

Biosensors & bioelectronics

Wang N, Ao H, Xiao W, Chen W, Li G, Wu J, Ju H.
PMID: 34999521
Biosens Bioelectron. 2022 Jan 04;201:113959. doi: 10.1016/j.bios.2021.113959. Epub 2022 Jan 04.

The quantitative detection of single cell secretions is always limited by their accurate collection and the heterogeneity of different cells. In this work, a confined electrochemiluminescence (ECL) imaging microarray (CEIM) chip was designed to capture single or a few...

Showing 1501 to 1511 of 1511 entries