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Showing 193 to 200 of 200 entries
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Reactive oxygen species limit intestinal mucosa-bacteria homeostasis in vitro.

Scientific reports

Luchan J, Choi C, Carrier RL.
PMID: 34887444
Sci Rep. 2021 Dec 09;11(1):23727. doi: 10.1038/s41598-021-02080-x.

Interactions between epithelial and immune cells with the gut microbiota have wide-ranging effects on many aspects of human health. Therefore, there is value in developing in vitro models capable of performing highly controlled studies of such interactions. However, several...

What underlies the observed hospital volume-outcome relationship?.

BMC health services research

Huguet M, Joutard X, Ray-Coquard I, Perrier L.
PMID: 35031047
BMC Health Serv Res. 2022 Jan 14;22(1):70. doi: 10.1186/s12913-021-07449-2.

BACKGROUND: Studies of the hospital volume-outcome relationship have highlighted that a greater volume activity improves patient outcomes. While this finding has been known for years, most studies to date have failed to delve into what underlies this relationship.OBJECTIVE: This...

Interpretable Machine Learning Model for Locoregional Relapse Prediction in Oropharyngeal Cancers.

Cancers

Giraud P, Giraud P, Nicolas E, Boisselier P, Alfonsi M, Rives M, Bardet E, Calugaru V, Noel G, Chajon E, Pommier P, Morelle M, Perrier L, Liem X, Burgun A, Bibault JE.
PMID: 33379188
Cancers (Basel). 2020 Dec 28;13(1). doi: 10.3390/cancers13010057.

BACKGROUND: There is no evidence to support surgery or radiotherapy as the best treatment for resectable oropharyngeal cancers with a negative HPV status. Predictive algorithms may help to decide which strategy to choose, but they will only be accepted...

The consequences of hesitation: Axelrod model with intrinsic noise.

PloS one

Perrier R, Gandica Y, Hernández L.
PMID: 34735501
PLoS One. 2021 Nov 04;16(11):e0259295. doi: 10.1371/journal.pone.0259295. eCollection 2021.

We study the influence of hesitating agents in the Axelrod model by introducing an intrinsic noise, which is proportional to the disagreement between the interacting agents, and thus coupled to the dynamics. Our results show that, unlike the effect...

Post-traumatic stress and stress disorders during the COVID-19 pandemic: Survey of emergency physicians.

Journal of the American College of Emergency Physicians open

Marco CA, Larkin GL, Feeser VR, Monti JE, Vearrier L.
PMID: 33392568
J Am Coll Emerg Physicians Open. 2020 Nov 02;1(6):1594-1601. doi: 10.1002/emp2.12305. eCollection 2020 Dec.

OBJECTIVE: Emergency physicians routinely encounter stressful clinical situations, including treating victims of crime, violence, and trauma; facing the deaths of patients; and delivering bad news. During a pandemic, stress may be increased for healthcare workers. This study was undertaken...

Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes.

JAMA oncology

Goudie C, Witkowski L, Cullinan N, Reichman L, Schiller I, Tachdjian M, Armstrong L, Blood KA, Brossard J, Brunga L, Cacciotti C, Caswell K, Cellot S, Clark ME, Clinton C, Coltin H, Felton K, Fernandez CV, Fleming AJ, Fuentes-Bolanos N, Gibson P, Grant R, Hammad R, Harrison LW, Irwin MS, Johnston DL, Kane S, Lafay-Cousin L, Lara-Corrales I, Larouche V, Mathews N, Meyn MS, Michaeli O, Perrier R, Pike M, Punnett A, Ramaswamy V, Say J, Somers G, Tabori U, Thibodeau ML, Toupin AK, Tucker KM, van Engelen K, Vairy S, Waespe N, Warby M, Wasserman JD, Whitlock JA, Sinnett D, Jabado N, Nathan PC, Shlien A, Kamihara J, Deyell RJ, Ziegler DS, Nichols KE, Dendukuri N, Malkin D, Villani A, Foulkes WD.
PMID: 34617981
JAMA Oncol. 2021 Dec 01;7(12):1806-1814. doi: 10.1001/jamaoncol.2021.4536.

IMPORTANCE: Prompt recognition of a child with a cancer predisposition syndrome (CPS) has implications for cancer management, surveillance, genetic counseling, and cascade testing of relatives. Diagnosis of CPS requires practitioner expertise, access to genetic testing, and test result interpretation....

Assembly of Indole Cores through a Palladium-Catalyzed Metathesis of Ar-X σ-Bonds.

Organic letters

Jafarpour F, Ghasemi M, Navid H, Safaie N, Rajai-Daryasarei S, Habibi A, Ferrier RC.
PMID: 33290655
Org Lett. 2020 Dec 18;22(24):9556-9561. doi: 10.1021/acs.orglett.0c03611. Epub 2020 Dec 08.

We describe the development of a new method for construction of highly substituted indole scaffolds through the strategic utilizing of the metathesis of Ar-X σ-bonds based on the dynamic nature of palladium-based oxidative addition/reductive elimination. A suitable and simple...

Assessing Unperceived Learning Needs in Continuing Medical Education for Primary Care Physicians: A Scoping Review.

The Journal of continuing education in the health professions

Armson H, Perrier L, Roder S, Shommu NS, Wakefield J, Shaw E, Zahorka S, Elmslie T, Lofft M.
PMID: 33284177
J Contin Educ Health Prof. 2020;40(4):257-267. doi: 10.1097/CEH.0000000000000300.

INTRODUCTION: Assessing needs before developing continuing medical education/continuing professional development (CME/CPD) programs is a crucial step in the education process. A previous systematic literature review described a lack of objective evaluation for learning needs assessments in primary care physicians....

Showing 193 to 200 of 200 entries