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Showing 13 to 24 of 104 entries
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Chiral alignment of OPV chromophores: exploitation of the ureidophthalimide-based foldamer.

Journal of the American Chemical Society

Sinkeldam RW, Hoeben FJ, Pouderoijen MJ, De Cat I, Zhang J, Furukawa S, De Feyter S, Vekemans JA, Meijer EW.
PMID: 17165764
J Am Chem Soc. 2006 Dec 20;128(50):16113-21. doi: 10.1021/ja063405d.

The ability of foldamers to adopt a secondary structure in solution has been exploited to organize peripheral functionality. Our previously reported poly(ureidophthalimide) foldamer proved to be an excellent scaffold for the chiral organization of peripherally positioned oligo(p-phenylenevinylene) (OPV) chromophores....

Identification of inorganic pigments used in porcelain cards based on fusing Raman and X-ray fluorescence (XRF) data.

Applied spectroscopy

Deneckere A, de Vries L, Vekemans B, Van de Voorde L, Ariese F, Vincze L, Moens L, Vandenabeele P.
PMID: 22054088
Appl Spectrosc. 2011 Nov;65(11):1281-90. doi: 10.1366/11-06368.

Raman spectroscopy and X-ray fluorescence (XRF) spectroscopy are often used as complementary techniques that are well suited for the analysis of art objects because both techniques are fast, sensitive, and noninvasive and measurements can take place in situ. In...

AN AUTOMATIC FEATURE BASED MODEL FOR CELL SEGMENTATION FROM CONFOCAL MICROSCOPY VOLUMES.

Proceedings. IEEE International Symposium on Biomedical Imaging

Delibaltov D, Ghosh P, Veeman M, Smith W, Manjunath BS.
PMID: 23154829
Proc IEEE Int Symp Biomed Imaging. 2011;199-203. doi: 10.1109/isbi.2011.5872387.

We present a model for the automated segmentation of cells from confocal microscopy volumes of biological samples. The segmentation task for these images is exceptionally challenging due to weak boundaries and varying intensity during the imaging process. To tackle...

Three-dimensional Fe speciation of an inclusion cloud within an ultradeep diamond by confocal μ-X-ray absorption near edge structure: evidence for late stage overprint.

Analytical chemistry

Silversmit G, Vekemans B, Appel K, Schmitz S, Schoonjans T, Brenker FE, Kaminsky F, Vincze L.
PMID: 21707095
Anal Chem. 2011 Aug 15;83(16):6294-9. doi: 10.1021/ac201073s. Epub 2011 Jul 14.

A stream of 1-20 μm sized mineral inclusions having the negative crystal shape of its host within an "ultra-deep" diamond from Rio Soriso (Juina area, Mato Grosso State, Brazil) has been studied with confocal μ-X-ray absorption near edge structure...

A CURVICYLINDRICAL COORDINATE SYSTEM FOR THE VISUALIZATION AND SEGMENTATION OF THE ASCIDIAN TAIL.

Proceedings. IEEE International Symposium on Biomedical Imaging

Abdollahian G, Veeman M, Smith W, Manjunath BS.
PMID: 23154852
Proc IEEE Int Symp Biomed Imaging. 2011;182-186. doi: 10.1109/isbi.2011.5872383.

State of the art biological imaging methods, such as confocal microscopy, create 3D volumes by sampling on a cartesian grid. This cartesian coordinate system is often not convenient for visualization and analysis of multi layered organs or tissues. The...

Hydrous mantle transition zone indicated by ringwoodite included within diamond.

Nature

Pearson DG, Brenker FE, Nestola F, McNeill J, Nasdala L, Hutchison MT, Matveev S, Mather K, Silversmit G, Schmitz S, Vekemans B, Vincze L.
PMID: 24622201
Nature. 2014 Mar 13;507(7491):221-4. doi: 10.1038/nature13080.

The ultimate origin of water in the Earth's hydrosphere is in the deep Earth--the mantle. Theory and experiments have shown that although the water storage capacity of olivine-dominated shallow mantle is limited, the Earth's transition zone, at depths between...

Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial.

Frontiers in immunology

van den Berg RA, Coccia M, Ballou WR, Kester KE, Ockenhouse CF, Vekemans J, Jongert E, Didierlaurent AM, van der Most RG.
PMID: 28588574
Front Immunol. 2017 May 23;8:557. doi: 10.3389/fimmu.2017.00557. eCollection 2017.

The RTS,S candidate malaria vaccine can protect against controlled human malaria infection (CHMI), but how protection is achieved remains unclear. Here, we have analyzed longitudinal peripheral blood transcriptome and immunogenicity data from a clinical efficacy trial in which healthy...

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP.

NPJ vaccines

Rampling T, Ewer KJ, Bowyer G, Edwards NJ, Wright D, Sridhar S, Payne R, Powlson J, Bliss C, Venkatraman N, Poulton ID, de Graaf H, Gbesemete D, Grobbelaar A, Davies H, Roberts R, Angus B, Ivinson K, Weltzin R, Rajkumar BY, Wille-Reece U, Lee C, Ockenhouse C, Sinden RE, Gerry SC, Lawrie AM, Vekemans J, Morelle D, Lievens M, Ballou RW, Lewis DJM, Cooke GS, Faust SN, Gilbert S, Hill AVS.
PMID: 30323956
NPJ Vaccines. 2018 Oct 09;3:49. doi: 10.1038/s41541-018-0084-2. eCollection 2018.

We assessed a combination multi-stage malaria vaccine schedule in which RTS,S/AS01B was given concomitantly with viral vectors expressing multiple-epitope thrombospondin-related adhesion protein (ME-TRAP) in a 0-month, 1-month, and 2-month schedule. RTS,S/AS01B was given as either three full doses or...

Highly Sensitive Nondestructive Rare Earth Element Detection by Means of Wavelength-Dispersive X-ray Fluorescence Spectroscopy Enabled by an Energy Dispersive pn-Charge-Coupled-Device Detector.

Analytical chemistry

De Pauw E, Tack P, Lindner M, Ashauer A, Garrevoet J, Vekemans B, Falkenberg G, Brenker FE, Vincze L.
PMID: 31774268
Anal Chem. 2020 Jan 07;92(1):1106-1113. doi: 10.1021/acs.analchem.9b04176. Epub 2019 Dec 12.

Detection of rare earth elements (REE) is commonly performed with destructive techniques such as (LA)-ICPMS or coupled to a destructive sample preparation. When investigating unique geological samples, such as cometary, asteroidal, or interstellar material from sample return missions or...

Immunogenicity and safety of AZD1222 (ChAdOx1 nCoV-19) against SARS-CoV-2 in Japan: a double-blind, randomized controlled phase 1/2 trial.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Asano M, Okada H, Itoh Y, Hirata H, Ishikawa K, Yoshida E, Matsui A, Kelly EJ, Shoemaker K, Olsson U, Vekemans J.
PMID: 34688944
Int J Infect Dis. 2022 Jan;114:165-174. doi: 10.1016/j.ijid.2021.10.030. Epub 2021 Oct 22.

BACKGROUND: Immunogenicity and safety of the AZD1222 (ChAdOx1 nCoV-19) vaccine was evaluated in Japanese adults in an ongoing phase 1/2, randomized, double-blind, parallel-group, placebo-controlled, multi-centre trial (NCT04568031).METHODS: Adults (n=256, age ≥18 years) seronegative for severe acute respiratory syndrome coronavirus-2...

Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial.

Frontiers in immunology

de Graaf H, Payne RO, Taylor I, Miura K, Long CA, Elias SC, Zaric M, Minassian AM, Silk SE, Li L, Poulton ID, Baker M, Draper SJ, Gbesemete D, Brendish NJ, Martins F, Marini A, Mekhaiel D, Edwards NJ, Roberts R, Vekemans J, Moyle S, Faust SN, Berrie E, Lawrie AM, Hill F, Hill AVS, Biswas S.
PMID: 34335606
Front Immunol. 2021 Jul 14;12:694759. doi: 10.3389/fimmu.2021.694759. eCollection 2021.

BACKGROUND: Transmission blocking vaccines targeting the sexual-stages of the malaria parasite could play a major role to achieve elimination and eradication of malaria. The METHODS: Clinical trial looking at safety and immunogenicity of two recombinant viral vectored vaccines encoding...

A phase 2/3, participant-blind, observer-blind, randomised, controlled study to assess the safety and immunogenicity of SII-ChAdOx1 nCoV-19 (COVID-19 vaccine) in adults in India.

EClinicalMedicine

Kulkarni PS, Padmapriyadarsini C, Vekemans J, Bavdekar A, Gupta M, Kulkarni P, Garg BS, Gogtay NJ, Tambe M, Lalwani S, Singh K, Munshi R, Meshram S, Selvavinayagam TS, Pandey K, Bhimarasetty DM, Ramakrishnan SR, Bhamare C, Dharmadhikari A, Vadakkedath R, Bonhomme CJ, Thakar M, Kurle SN, Kelly EJ, Gautam M, Gupta N, Panda S, Bhargava B, Shaligram U, Kapse D, Gunale B.
PMID: 34870133
EClinicalMedicine. 2021 Dec;42:101218. doi: 10.1016/j.eclinm.2021.101218. Epub 2021 Nov 30.

BACKGROUND: This phase 2/3 immunobridging study evaluated the safety and immunogenicity of the ChAdOx1 nCoV-19 Coronavirus Vaccine (Recombinant) (SII-ChAdOx1 nCoV-19), manufactured in India at the Serum Institute of India Pvt Ltd (SIIPL), following technology transfer from the AstraZeneca.METHODS: This...

Showing 13 to 24 of 104 entries