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Showing 85 to 93 of 93 entries
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Computerised patient-specific prediction of the recovery profile of upper limb capacity within stroke services: the next step.

Journal of neurology, neurosurgery, and psychiatry

Selles RW, Andrinopoulou ER, Nijland RH, van der Vliet R, Slaman J, van Wegen EE, Rizopoulos D, Ribbers GM, Meskers CG, Kwakkel G.
PMID: 33479046
J Neurol Neurosurg Psychiatry. 2021 Jan 21; doi: 10.1136/jnnp-2020-324637. Epub 2021 Jan 21.

INTRODUCTION: Predicting upper limb capacity recovery is important to set treatment goals, select therapies and plan discharge. We introduce a prediction model of the patient-specific profile of upper limb capacity recovery up to 6 months poststroke by incorporating all...

Redox Dysregulation in Aging and COPD: Role of NOX Enzymes and Implications for Antioxidant Strategies.

Antioxidants (Basel, Switzerland)

Schiffers C, Reynaert NL, Wouters EFM, van der Vliet A.
PMID: 34829671
Antioxidants (Basel). 2021 Nov 11;10(11). doi: 10.3390/antiox10111799.

With a rapidly growing elderly human population, the incidence of age-related lung diseases such as chronic obstructive pulmonary disease (COPD) continues to rise. It is widely believed that reactive oxygen species (ROS) play an important role in ageing and...

Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.

Journal of immunology (Baltimore, Md. : 1950)

Dustin CM, Habibovic A, Hristova M, Schiffers C, Morris CR, Lin MJ, Bauer RA, Heppner DE, Daphtary N, Aliyeva M, van der Vliet A.
PMID: 34088769
J Immunol. 2021 Jun 15;206(12):2989-2999. doi: 10.4049/jimmunol.2000995. Epub 2021 Jun 04.

The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these responses is the IL-1 family cytokine IL-33, which is...

Natural Killer Cells and Anti-Cancer Therapies: Reciprocal Effects on Immune Function and Therapeutic Response.

Cancers

Toffoli EC, Sheikhi A, Höppner YD, de Kok P, Yazdanpanah-Samani M, Spanholtz J, Verheul HMW, van der Vliet HJ, de Gruijl TD.
PMID: 33572396
Cancers (Basel). 2021 Feb 09;13(4). doi: 10.3390/cancers13040711.

Natural Killer (NK) cells are innate immune cells with the unique ability to recognize and kill virus-infected and cancer cells without prior immune sensitization. Due to their expression of the Fc receptor CD16, effector NK cells can kill tumor...

Thioether-Based Polymeric Micelles with Fine-Tuned Oxidation Sensitivities for Chemotherapeutic Drug Delivery.

Biomacromolecules

van der Vlies AJ, Xu J, Ghasemi M, Bator C, Bell A, Rosoff-Verbit B, Liu B, Gomez ED, Hasegawa U.
PMID: 34762396
Biomacromolecules. 2021 Nov 11; doi: 10.1021/acs.biomac.1c01010. Epub 2021 Nov 11.

Oxidation-sensitive drug delivery systems (DDSs) have attracted attention due to the potential to improve efficacy and safety of chemotherapeutics. These systems are designed to release the payload in response to oxidative stress conditions, which are associated with many types...

Enhancement of NK Cell Antitumor Effector Functions Using a Bispecific Single Domain Antibody Targeting CD16 and the Epidermal Growth Factor Receptor.

Cancers

Toffoli EC, Sheikhi A, Lameris R, King LA, van Vliet A, Walcheck B, Verheul HMW, Spanholtz J, Tuynman J, de Gruijl TD, van der Vliet HJ.
PMID: 34771609
Cancers (Basel). 2021 Oct 29;13(21). doi: 10.3390/cancers13215446.

The ability to kill tumor cells while maintaining an acceptable safety profile makes Natural Killer (NK) cells promising assets for cancer therapy. Strategies to enhance the preferential accumulation and activation of NK cells in the tumor microenvironment can be...

Factors associated with longitudinal change of meniscal extrusion in overweight women without clinical signs of osteoarthritis.

Rheumatology (Oxford, England)

van der Voet JA, Wesselius D, Zhang F, Vroegindeweij D, Oei EH, Bierma-Zeinstra SMA, Englund M, Runhaar J.
PMID: 33693533
Rheumatology (Oxford). 2021 Nov 03;60(11):5175-5184. doi: 10.1093/rheumatology/keab228.

OBJECTIVES: To identify variables associated with longitudinal change in meniscal extrusion, which might be used as possible targets for knee osteoarthritis (KOA) prevention.METHODS: In a high-risk population of middle-aged overweight women, meniscal extrusion was assessed with magnetic resonance imaging...

Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.

Journal of immunology (Baltimore, Md. : 1950)

Dustin CM, Habibovic A, Hristova M, Schiffers C, Morris CR, Lin MJ, Bauer RA, Heppner DE, Daphtary N, Aliyeva M, van der Vliet A.
PMID: 34088769
J Immunol. 2021 Jun 15;206(12):2989-2999. doi: 10.4049/jimmunol.2000995. Epub 2021 Jun 04.

The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these responses is the IL-1 family cytokine IL-33, which is...

Hydrogen sulfide-releasing micelles for promoting angiogenesis.

Polymer chemistry

Chen JJY, van der Vlies AJ, Hasegawa U.
PMID: 33796157
Polym Chem. 2020 Jul 21;11:4454-4463. doi: 10.1039/d0py00495b. Epub 2020 Jun 16.

Hydrogen sulfide (H

Showing 85 to 93 of 93 entries