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Showing 13 to 24 of 93 entries
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Pancreatic Cancer and Immunotherapy: A Clinical Overview.

Cancers

Timmer FEF, Geboers B, Nieuwenhuizen S, Dijkstra M, Schouten EAC, Puijk RS, de Vries JJJ, van den Tol MP, Bruynzeel AME, Streppel MM, Wilmink JW, van der Vliet HJ, Meijerink MR, Scheffer HJ, de Gruijl TD.
PMID: 34439292
Cancers (Basel). 2021 Aug 17;13(16). doi: 10.3390/cancers13164138.

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with high mortality. The vast majority of patients present with unresectable, advanced stage disease, for whom standard of care chemo(radio)therapy may improve survival by several months. Immunotherapy has led to a...

Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols.

Biomaterials science

Mosiewicz KA, Kolb L, van der Vlies AJ, Lutolf MP.
PMID: 32481945
Biomater Sci. 2014 Nov 30;2(11):1640-1651. doi: 10.1039/c4bm00262h. Epub 2014 Sep 04.

Mammalian cell behavior is strongly influenced by physical and chemical cues originating from the extracellular matrix (ECM). In vivo, ECM signals are displayed in a spatiotemporally complex fashion, often composed as gradients and in concentration profiles that change in...

Elucidating the degradation mechanism of the cathode catalyst of PEFCs by a combination of electrochemical methods and X-ray fluorescence spectroscopy.

Physical chemistry chemical physics : PCCP

Monzó J, van der Vliet DF, Yanson A, Rodriguez P.
PMID: 27464340
Phys Chem Chem Phys. 2016 Aug 10;18(32):22407-15. doi: 10.1039/c6cp03795j.

In this study, we report a methodology which enables the determination of the degradation mechanisms responsible for catalyst deterioration under different accelerated stress protocols (ASPs) by combining measurements of the electrochemical surface area (ECSA) and Pt content (by X-ray...

Airborne SARS-CoV-2 in home and hospital environments investigated with a high-powered air sampler.

The Journal of hospital infection

de Man P, Ortiz MA, Bluyssen PM, de Man SJ, Rentmeester MJ, van der Vliet M, Wils EJ, Ong DSY.
PMID: 34752804
J Hosp Infect. 2021 Nov 06; doi: 10.1016/j.jhin.2021.10.018. Epub 2021 Nov 06.

BACKGROUND: The initial aim was to study the effects of face masks worn by recently infected individuals on the airborne spread of SARS-CoV-2, but findings motivated us to proceed with comparing the presence of SARS-CoV-2 in air samples near...

Bulldozing β-linked glycolipids for recognition by invariant NKT cells.

Immunotherapy

de Bruin RC, Schneiders FL, Santegoets SJ, Verheul HM, de Gruijl TD, van der Vliet HJ.
PMID: 22263253
Immunotherapy. 2012 Jan;4(1):20.

No abstract available.

Clinical evaluation of the efficacy of methylnaltrexone in resolving constipation induced by different opioid subtypes combined with laboratory analysis of immunomodulatory and antiangiogenic effects of methylnaltrexone.

BMC palliative care

Neefjes EC, van der Vorst MJ, Boddaert MS, Zuurmond WW, van der Vliet HJ, Beeker A, van den Berg HP, van Groeningen CJ, Vrijaldenhoven S, Verheul HM.
PMID: 25165428
BMC Palliat Care. 2014 Aug 20;13:42. doi: 10.1186/1472-684X-13-42. eCollection 2014.

BACKGROUND: Opioid-induced constipation (OIC) is one of the major symptoms in palliative care with a prevalence of 30-50%. Methylnaltrexone for the treatment of OIC is significantly more effective than placebo, but only in about fifty percent of the patients...

Treatment of a traumatic carotid-cavernous fistula with a covered stent: some considerations. Case report.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

Meijer FJ, Van Der Vliet AM.
PMID: 20465898
Interv Neuroradiol. 2009 Jul 29;15(2):191-6. doi: 10.1177/159101990901500209. Epub 2009 Sep 01.

SUMMARY: This article discusses some considerations concerning covered stent placement in a patient with a traumatic direct carotid-cavernous fistula. Our case supports recent reports in the literature that covered stent placement can be an acceptable alternative when detachable balloon...

Corrigendum. Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4.

Epigenetics

Balog J, Thijssen PE, Shadle S, Straasheijm KR, van der Vliet PJ, Krom YD, van den Boogaard ML, de Jong A, Lemmers RJ, Tawil R, Tapscott SJ, van der Maarel SM.
PMID: 27058812
Epigenetics. 2016;11(2):175. doi: 10.1080/15592294.2016.1161273.

No abstract available.

Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.

Oncoimmunology

Werter IM, Schneiders FL, Scotet E, Verheul HM, de Gruijl TD, van der Vliet HJ.
PMID: 25941612
Oncoimmunology. 2014 Dec 08;3(9):e955343. doi: 10.4161/21624011.2014.955343. eCollection 2014 Oct.

CD1d-restricted invariant natural killer T cells (iNKT) constitute an important immunoregulatory T-cell subset involved in the induction of antitumor immune responses. Here, we provide a view on the recent observation that Vγ9Vδ2-T cells, through trogocytosis of CD1d-containing membrane fragments,...

NMR spectra and electrochemical behavior of catechol-bearing block copolymer micelles.

Data in brief

Hasegawa U, Moriyama M, Uyama H, van der Vlies AJ.
PMID: 26217751
Data Brief. 2015 Apr 22;4:1-6. doi: 10.1016/j.dib.2015.04.004. eCollection 2015 Sep.

Here, we provide the NMR spectra and AFM data for antioxidant micelles prepared from amphiphilic PAM-PDA block copolymers composed of a poly(N-acryloyl morpholine) and a redox-active catechol-bearing block with different catechol content. We also provide details of the electrochemical...

Correction: Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody.

Journal of immunology (Baltimore, Md. : 1950)

de Bruin RCG, Stam AGM, Vangone A, van Bergen En Henegouwen PMP, Verheul HMW, Sebestyén Z, Kuball J, Bonvin AMJJ, de Gruijl TD, van der Vliet HJ.
PMID: 28416722
J Immunol. 2017 May 01;198(9):3759. doi: 10.4049/jimmunol.1700317.

No abstract available.

Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.

Journal of immunology (Baltimore, Md. : 1950)

Dustin CM, Habibovic A, Hristova M, Schiffers C, Morris CR, Lin MJ, Bauer RA, Heppner DE, Daphtary N, Aliyeva M, van der Vliet A.
PMID: 34088769
J Immunol. 2021 Jun 15;206(12):2989-2999. doi: 10.4049/jimmunol.2000995. Epub 2021 Jun 04.

The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these responses is the IL-1 family cytokine IL-33, which is...

Showing 13 to 24 of 93 entries