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Showing 13 to 23 of 23 entries
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Prolonged Complete Response in a Patient with Metastatic Pancreatic Adenocarcinoma after FOLFIRINOX Chemotherapy and Maintenance with FOLFIRI.

Case reports in oncological medicine

Nikolaou C, Matikas A, Papavasilopoulou M, Mavroudis D, Vamvakas L.
PMID: 26090249
Case Rep Oncol Med. 2015;2015:659624. doi: 10.1155/2015/659624. Epub 2015 May 21.

Metastatic pancreatic adenocarcinoma confers a poor prognosis. Even with recent advances in the treatment of this disease with the introduction of two modestly effective chemotherapy regimens, complete responses are still very rare. Moreover, there are no published data on...

The contribution of transgenic plants to better health through improved nutrition: opportunities and constraints.

Genes & nutrition

Pérez-Massot E, Banakar R, Gómez-Galera S, Zorrilla-López U, Sanahuja G, Arjó G, Miralpeix B, Vamvaka E, Farré G, Rivera SM, Dashevskaya S, Berman J, Sabalza M, Yuan D, Bai C, Bassie L, Twyman RM, Capell T, Christou P, Zhu C.
PMID: 22926437
Genes Nutr. 2013 Jan;8(1):29-41. doi: 10.1007/s12263-012-0315-5. Epub 2012 Aug 29.

Malnutrition is a prevalent and entrenched global socioeconomic challenge that reflects the combined impact of poverty, poor access to food, inefficient food distribution infrastructure, and an over-reliance on subsistence mono-agriculture. The dependence on staple cereals lacking many essential nutrients...

Voxel based internal dosimetry during radionuclide therapy.

Hellenic journal of nuclear medicine

Vamvakas I, Lyra M.
PMID: 26665215
Hell J Nucl Med. 2015 Sep-Dec;18:76-80.

BACKGROUND: Many radionuclides have been used for several decades in cancer treatment. (131)I, (90)Y, (89)Sr, (111)In, (177)Lu and (223)Ra are some of the most widely used radioisotopes. Therapeutic results and side effects can be associated only if the absorbed...

Mesothelial cyst of the round ligament misdiagnosed as irreducible inguinal hernia.

Case reports in surgery

Manatakis DK, Stamos N, Agalianos C, Vamvakas P, Kordelas A, Davides D.
PMID: 24159409
Case Rep Surg. 2013;2013:408078. doi: 10.1155/2013/408078. Epub 2013 Sep 18.

We report the case of a 36-year-old woman who presented with signs and symptoms of an irreducible inguinal hernia. Surgical exploration revealed a mesothelial cyst of the round ligament of the uterus. Mesothelial cysts of the round ligament are...

Digital technologies for medicines: shaping a framework for success.

Nature reviews. Drug discovery

Cerreta F, Ritzhaupt A, Metcalfe T, Askin S, Duarte J, Berntgen M, Vamvakas S.
PMID: 32398879
Nat Rev Drug Discov. 2020 Sep;19(9):573-574. doi: 10.1038/d41573-020-00080-6.

No abstract available.

Post-Traumatic Stress Disorder and Burnout in Healthcare Professionals During the SARS-CoV-2 Pandemic: a Cross-Sectional Study.

Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)

Ilias I, Mantziou V, Vamvakas E, Kampisiouli E, Theodorakopoulou M, Vrettou C, Douka E, Vassiliou AG, Orfanos S, Kotanidou A, Dimopoulou I.
PMID: 34722899
J Crit Care Med (Targu Mures). 2021 Jan 29;7(1):14-20. doi: 10.2478/jccm-2020-0042. eCollection 2021 Jan.

INTRODUCTION: Healthcare professionals who are directly involved in the diagnosis, treatment, and general care of patients with SARS-CoV-2 are at risk of developing adverse psychological reactions. A cross-sectional study of healthcare professionals aimed to determine the impact of the...

Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer.

World journal of surgical oncology

Kouraklis G, Theocharis S, Vamvakas P, Vagianos C, Glinavou A, Giaginis C, Sioka C.
PMID: 16426443
World J Surg Oncol. 2006 Jan 20;4:5. doi: 10.1186/1477-7819-4-5.

BACKGROUND: Cyclin D1 plays a major role as a potential contributor to the multistep process of oncogenesis; nevertheless its prognostic significance in colon cancer has already been examined in a few studies and needs to be further delineated. The...

Favorable clinical course of patients experiencing bevacizumab-induced proteinuria.

Case reports in oncology

Saloustros E, Androulakis N, Vamvakas L, Mavroudis D, Georgoulias V.
PMID: 21537380
Case Rep Oncol. 2010 Oct 12;3(3):368-71. doi: 10.1159/000321630.

Nephrotic-range proteinuria, which denotes structural damage to the glomerular filtration barrier, occurs in 1-2% of bevacizumab-treated patients. The glomerular injury and subsequent proteinuria is probably due to a direct targeting of vascular endothelial growth factor (VEGF). We report a...

Are Novel, Nonrandomized Analytic Methods Fit for Decision Making? The Need for Prospective, Controlled, and Transparent Validation.

Clinical pharmacology and therapeutics

Eichler HG, Koenig F, Arlett P, Enzmann H, Humphreys A, Pétavy F, Schwarzer-Daum B, Sepodes B, Vamvakas S, Rasi G.
PMID: 31574163
Clin Pharmacol Ther. 2020 Apr;107(4):773-779. doi: 10.1002/cpt.1638. Epub 2019 Oct 01.

Real-world data and patient-level data from completed randomized controlled trials are becoming available for secondary analysis on an unprecedented scale. A range of novel methodologies and study designs have been proposed for their analysis or combination. However, to make...

Nab-paclitaxel as second-line treatment in advanced gastric cancer: a multicenter phase II study of the Hellenic Oncology Research Group.

Annals of gastroenterology

Katsaounis P, Kotsakis A, Kentepozidis N, Polyzos A, Bakogeorgos M, Koinis F, Vamvakas L, Vardakis N, Kalbakis K, Boukovinas I, Varthalitis II, Prinarakis E, Georgoulias V, Souglakos J.
PMID: 29333068
Ann Gastroenterol. 2018 Jan-Feb;31(1):65-70. doi: 10.20524/aog.2017.0215. Epub 2017 Nov 27.

BACKGROUND: This study evaluated the safety and efficacy of nab-paclitaxel as second-line treatment in patients with advanced gastric adenocarcinoma.METHODS: Thirty-nine pretreated patients [33 with taxane-based regimens (docetaxel, cisplatin, and fluorouracil)] and 6 with combination of fluoropyrimidines plus cisplatin with...

MicroRNAs Regulating Tumor and Immune Cell Interactions in the Prediction of Relapse in Early Stage Breast Cancer.

Biomedicines

Papadaki C, Thomopoulou K, Monastirioti A, Koronakis G, Papadaki MA, Rounis K, Vamvakas L, Nikolaou C, Mavroudis D, Agelaki S.
PMID: 33924670
Biomedicines. 2021 Apr 13;9(4). doi: 10.3390/biomedicines9040421.

MicroRNAs (miRNAs) are involved in the regulation of immune response and hold an important role in tumor immune escape. We investigated the differential expression of the immunomodulatory miR-10b, miR-19a, miR-20a, miR-126, and miR-155 in the plasma of healthy women...

Showing 13 to 23 of 23 entries