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Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice.

Veterinary pathology

Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM.
PMID: 34467820
Vet Pathol. 2021 Sep 01;3009858211043084. doi: 10.1177/03009858211043084. Epub 2021 Sep 01.

Several animal models have been developed to study the pathophysiology of SARS-CoV-2 infection and to evaluate vaccines and therapeutic agents for this emerging disease. Similar to infection with SARS-CoV-1, infection of Syrian hamsters with SARS-CoV-2 results in moderate respiratory...

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Yen HL, Valkenburg S, Sia SF, et al. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2021;3009858211043084doi: 10.1177/03009858211043084.
Yen, H. L., Valkenburg, S., Sia, S. F., Choy, K. T., Peiris, J. S. M., Wong, K. H. M., Crossland, N., Douam, F., & Nicholls, J. M. (2021). Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Veterinary pathology, 3009858211043084. https://doi.org/10.1177/03009858211043084
Yen, Hui-Ling, et al. "Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice." Veterinary pathology vol. (2021): 3009858211043084. doi: https://doi.org/10.1177/03009858211043084
Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2021 Sep 01;3009858211043084. doi: 10.1177/03009858211043084. Epub 2021 Sep 01. PMID: 34467820.
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Social media use and well-being: What we know and what we need to know.

Current opinion in psychology

Valkenburg PM.
PMID: 35016087
Curr Opin Psychol. 2021 Dec 20;45:101294. doi: 10.1016/j.copsyc.2021.12.006. Epub 2021 Dec 20.

Research into the impact of social media use (SMU) on well-being (e.g., happiness) and ill-being (e.g., depression) has exploded over the past few years. From 2019 to August 2021, 27 reviews have been published: nine meta-analyses, nine systematic reviews,...

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Valkenburg PM. Social media use and well-being: What we know and what we need to know. Curr Opin Psychol. 2021;45:101294doi: 10.1016/j.copsyc.2021.12.006.
Valkenburg, P. M. (2021). Social media use and well-being: What we know and what we need to know. Current opinion in psychology, 45101294. https://doi.org/10.1016/j.copsyc.2021.12.006
Valkenburg, Patti M. "Social media use and well-being: What we know and what we need to know." Current opinion in psychology vol. 45 (2021): 101294. doi: https://doi.org/10.1016/j.copsyc.2021.12.006
Valkenburg PM. Social media use and well-being: What we know and what we need to know. Curr Opin Psychol. 2021 Dec 20;45:101294. doi: 10.1016/j.copsyc.2021.12.006. Epub 2021 Dec 20. PMID: 35016087.
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Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong.

Respirology (Carlton, Vic.)

Mok CKP, Cohen CA, Cheng SMS, Chen C, Kwok KO, Yiu K, Chan TO, Bull M, Ling KC, Dai Z, Ng SS, Lui GC, Wu C, Amarasinghe GK, Leung DW, Wong SYS, Valkenburg SA, Peiris M, Hui DS.
PMID: 34820940
Respirology. 2021 Nov 24; doi: 10.1111/resp.14191. Epub 2021 Nov 24.

BACKGROUND AND OBJECTIVE: Few head-to-head evaluations of immune responses to different vaccines have been reported.METHODS: Surrogate virus neutralization test (sVNT) antibody levels of adults receiving either two doses of BNT162b2 (n = 366) or CoronaVac (n = 360) vaccines...

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Mok CKP, Cohen CA, Cheng SMS, et al. Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong. Respirology. 2021;doi: 10.1111/resp.14191.
Mok, C. K. P., Cohen, C. A., Cheng, S. M. S., Chen, C., Kwok, K. O., Yiu, K., Chan, T. O., Bull, M., Ling, K. C., Dai, Z., Ng, S. S., Lui, G. C., Wu, C., Amarasinghe, G. K., Leung, D. W., Wong, S. Y. S., Valkenburg, S. A., Peiris, M., & Hui, D. S. (2021). Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong. Respirology (Carlton, Vic.), . https://doi.org/10.1111/resp.14191
Mok, Chris Ka Pun, et al. "Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong." Respirology (Carlton, Vic.) vol. (2021). doi: https://doi.org/10.1111/resp.14191
Mok CKP, Cohen CA, Cheng SMS, Chen C, Kwok KO, Yiu K, Chan TO, Bull M, Ling KC, Dai Z, Ng SS, Lui GC, Wu C, Amarasinghe GK, Leung DW, Wong SYS, Valkenburg SA, Peiris M, Hui DS. Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong. Respirology. 2021 Nov 24; doi: 10.1111/resp.14191. Epub 2021 Nov 24. PMID: 34820940.
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Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults.

NPJ vaccines

Li APY, Cohen CA, Leung NHL, Fang VJ, Gangappa S, Sambhara S, Levine MZ, Iuliano AD, Perera RAPM, Ip DKM, Peiris JSM, Thompson MG, Cowling BJ, Valkenburg SA.
PMID: 33594050
NPJ Vaccines. 2021 Feb 16;6(1):25. doi: 10.1038/s41541-021-00289-5.

The vaccine efficacy of standard-dose seasonal inactivated influenza vaccines (S-IIV) can be improved by the use of vaccines with higher antigen content or adjuvants. We conducted a randomized controlled trial in older adults to compare cellular and antibody responses...

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Li APY, Cohen CA, Leung NHL, et al. Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults. NPJ Vaccines. 2021;6(1):25doi: 10.1038/s41541-021-00289-5.
Li, A. P. Y., Cohen, C. A., Leung, N. H. L., Fang, V. J., Gangappa, S., Sambhara, S., Levine, M. Z., Iuliano, A. D., Perera, R. A. P. M., Ip, D. K. M., Peiris, J. S. M., Thompson, M. G., Cowling, B. J., & Valkenburg, S. A. (2021). Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults. NPJ vaccines, 6(1), 25. https://doi.org/10.1038/s41541-021-00289-5
Li, Athena P Y, et al. "Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults." NPJ vaccines vol. 6,1 (2021): 25. doi: https://doi.org/10.1038/s41541-021-00289-5
Li APY, Cohen CA, Leung NHL, Fang VJ, Gangappa S, Sambhara S, Levine MZ, Iuliano AD, Perera RAPM, Ip DKM, Peiris JSM, Thompson MG, Cowling BJ, Valkenburg SA. Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults. NPJ Vaccines. 2021 Feb 16;6(1):25. doi: 10.1038/s41541-021-00289-5. PMID: 33594050; PMCID: PMC7886864.
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T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants.

Frontiers in medicine

Nguyen THO, Cohen CA, Rowntree LC, Bull MB, Hachim A, Kedzierska K, Valkenburg SA.
PMID: 35004764
Front Med (Lausanne). 2021 Dec 24;8:793102. doi: 10.3389/fmed.2021.793102. eCollection 2021.

T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T cell responses plays a role in the development of severe COVID-19 and...

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Nguyen THO, Cohen CA, Rowntree LC, et al. T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Front Med (Lausanne). 2021;8:793102doi: 10.3389/fmed.2021.793102.
Nguyen, T. H. O., Cohen, C. A., Rowntree, L. C., Bull, M. B., Hachim, A., Kedzierska, K., & Valkenburg, S. A. (2021). T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Frontiers in medicine, 8793102. https://doi.org/10.3389/fmed.2021.793102
Nguyen, Thi H O, et al. "T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants." Frontiers in medicine vol. 8 (2021): 793102. doi: https://doi.org/10.3389/fmed.2021.793102
Nguyen THO, Cohen CA, Rowntree LC, Bull MB, Hachim A, Kedzierska K, Valkenburg SA. T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Front Med (Lausanne). 2021 Dec 24;8:793102. doi: 10.3389/fmed.2021.793102. eCollection 2021. PMID: 35004764; PMCID: PMC8739267.
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Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations.

Pediatric research

de Hoogd S, Goulooze SC, Valkenburg AJ, Krekels EHJ, van Dijk M, Tibboel D, Knibbe CAJ.
PMID: 33603216
Pediatr Res. 2021 Dec;90(6):1201-1206. doi: 10.1038/s41390-021-01383-z. Epub 2021 Feb 18.

BACKGROUND: Morphine is commonly used for postoperative analgesia in children. Here we studied the pharmacodynamics of morphine in children after cardiac surgery receiving protocolized morphine.METHODS: Data on morphine rescue requirements guided by validated pain scores in children (n =...

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de Hoogd S, Goulooze SC, Valkenburg AJ, et al. Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations. Pediatr Res. 2021;90(6):1201-1206doi: 10.1038/s41390-021-01383-z.
de Hoogd, S., Goulooze, S. C., Valkenburg, A. J., Krekels, E. H. J., van Dijk, M., Tibboel, D., & Knibbe, C. A. J. (2021). Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations. Pediatric research, 90(6), 1201-1206. https://doi.org/10.1038/s41390-021-01383-z
de Hoogd, Sjoerd, et al. "Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations." Pediatric research vol. 90,6 (2021): 1201-1206. doi: https://doi.org/10.1038/s41390-021-01383-z
de Hoogd S, Goulooze SC, Valkenburg AJ, Krekels EHJ, van Dijk M, Tibboel D, Knibbe CAJ. Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations. Pediatr Res. 2021 Dec;90(6):1201-1206. doi: 10.1038/s41390-021-01383-z. Epub 2021 Feb 18. PMID: 33603216.
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Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice.

Veterinary pathology

Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM.
PMID: 34467820
Vet Pathol. 2021 Sep 01;3009858211043084. doi: 10.1177/03009858211043084. Epub 2021 Sep 01.

Several animal models have been developed to study the pathophysiology of SARS-CoV-2 infection and to evaluate vaccines and therapeutic agents for this emerging disease. Similar to infection with SARS-CoV-1, infection of Syrian hamsters with SARS-CoV-2 results in moderate respiratory...

Cite
Yen HL, Valkenburg S, Sia SF, et al. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2021;3009858211043084doi: 10.1177/03009858211043084.
Yen, H. L., Valkenburg, S., Sia, S. F., Choy, K. T., Peiris, J. S. M., Wong, K. H. M., Crossland, N., Douam, F., & Nicholls, J. M. (2021). Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Veterinary pathology, 3009858211043084. https://doi.org/10.1177/03009858211043084
Yen, Hui-Ling, et al. "Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice." Veterinary pathology vol. (2021): 3009858211043084. doi: https://doi.org/10.1177/03009858211043084
Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2021 Sep 01;3009858211043084. doi: 10.1177/03009858211043084. Epub 2021 Sep 01. PMID: 34467820; PMCID: PMC8721337.
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Louse flies in Azorean and mainland populations of four Passeriformes species: A new perspective to parasite Island syndromes.

International journal for parasitology. Parasites and wildlife

Tomás A, Pereira da Fonseca I, Valkenburg T, Rebelo MT.
PMID: 33384921
Int J Parasitol Parasites Wildl. 2020 Dec 22;14:33-40. doi: 10.1016/j.ijppaw.2020.12.004. eCollection 2021 Apr.

Hippoboscid flies, also known as louse flies, are obligate blood-feeders ectoparasites of birds and mammals. By studying louse fly parasites of four Passeriformes species, Eurasian blackbird (

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Tomás A, Pereira da Fonseca I, Valkenburg T, et al. Louse flies in Azorean and mainland populations of four Passeriformes species: A new perspective to parasite Island syndromes. Int J Parasitol Parasites Wildl. 2020;14:33-40doi: 10.1016/j.ijppaw.2020.12.004.
Tomás, A., Pereira da Fonseca, I., Valkenburg, T., & Rebelo, M. T. (2021). Louse flies in Azorean and mainland populations of four Passeriformes species: A new perspective to parasite Island syndromes. International journal for parasitology. Parasites and wildlife, 1433-40. https://doi.org/10.1016/j.ijppaw.2020.12.004
Tomás, André, et al. "Louse flies in Azorean and mainland populations of four Passeriformes species: A new perspective to parasite Island syndromes." International journal for parasitology. Parasites and wildlife vol. 14 (2021): 33-40. doi: https://doi.org/10.1016/j.ijppaw.2020.12.004
Tomás A, Pereira da Fonseca I, Valkenburg T, Rebelo MT. Louse flies in Azorean and mainland populations of four Passeriformes species: A new perspective to parasite Island syndromes. Int J Parasitol Parasites Wildl. 2020 Dec 22;14:33-40. doi: 10.1016/j.ijppaw.2020.12.004. eCollection 2021 Apr. PMID: 33384921; PMCID: PMC7770506.
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T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants.

Frontiers in medicine

Nguyen THO, Cohen CA, Rowntree LC, Bull MB, Hachim A, Kedzierska K, Valkenburg SA.
PMID: 35004764
Front Med (Lausanne). 2021 Dec 24;8:793102. doi: 10.3389/fmed.2021.793102. eCollection 2021.

T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T cell responses plays a role in the development of severe COVID-19 and...

Cite
Nguyen THO, Cohen CA, Rowntree LC, et al. T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Front Med (Lausanne). 2021;8:793102doi: 10.3389/fmed.2021.793102.
Nguyen, T. H. O., Cohen, C. A., Rowntree, L. C., Bull, M. B., Hachim, A., Kedzierska, K., & Valkenburg, S. A. (2021). T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Frontiers in medicine, 8793102. https://doi.org/10.3389/fmed.2021.793102
Nguyen, Thi H O, et al. "T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants." Frontiers in medicine vol. 8 (2021): 793102. doi: https://doi.org/10.3389/fmed.2021.793102
Nguyen THO, Cohen CA, Rowntree LC, Bull MB, Hachim A, Kedzierska K, Valkenburg SA. T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants. Front Med (Lausanne). 2021 Dec 24;8:793102. doi: 10.3389/fmed.2021.793102. eCollection 2021. PMID: 35004764; PMCID: PMC8739267.
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Tracking ecology over geological time: evolution within guilds of vertebrates.

Trends in ecology & evolution

Valkenburgh BV.
PMID: 21236956
Trends Ecol Evol. 1995 Feb;10(2):71-6. doi: 10.1016/S0169-5347(00)88980-6. Epub 2000 Aug 01.

Community structure, stability and change can be observed in the fossil record over timescales that far exceed what is possible in the present. Recent quantitative studies on ecological structure withion ancient guilds of various vertebrate predators, inlcuding birds, mammals...

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Valkenburgh BV. Tracking ecology over geological time: evolution within guilds of vertebrates. Trends Ecol Evol. 2000;10(2):71-6doi: 10.1016/S0169-5347(00)88980-6.
Valkenburgh, B. V. (1995). Tracking ecology over geological time: evolution within guilds of vertebrates. Trends in ecology & evolution, 10(2), 71-6. https://doi.org/10.1016/S0169-5347(00)88980-6
Valkenburgh, B V. "Tracking ecology over geological time: evolution within guilds of vertebrates." Trends in ecology & evolution vol. 10,2 (1995): 71-6. doi: https://doi.org/10.1016/S0169-5347(00)88980-6
Valkenburgh BV. Tracking ecology over geological time: evolution within guilds of vertebrates. Trends Ecol Evol. 1995 Feb;10(2):71-6. doi: 10.1016/S0169-5347(00)88980-6. Epub 2000 Aug 01. PMID: 21236956.
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A prospective randomised study comparing a GnRH-antagonist versus a GnRH-agonist short protocol for ovarian stimulation in patients referred for IVF.

Facts, views & vision in ObGyn

Gordts S, Van Turnhout C, Campo R, Puttemans P, Valkenburg M, Gordts S.
PMID: 24753894
Facts Views Vis Obgyn. 2012;4(2):82-7.

OBJECTIVE: To compare two short protocols for ovarian stimulation in IVF cycles using an antagonist and an agonist short protocol. The outcomes studied were dosis rec FSH needed, days of stimulation, number of oocytes retrieved and pregnancy outcome.METHODS: A...

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Gordts S, Van Turnhout C, Campo R, et al. A prospective randomised study comparing a GnRH-antagonist versus a GnRH-agonist short protocol for ovarian stimulation in patients referred for IVF. Facts Views Vis Obgyn. 2012;4(2):82-7
Gordts, S., Van Turnhout, C., Campo, R., Puttemans, P., Valkenburg, M., & Gordts, S. (2012). A prospective randomised study comparing a GnRH-antagonist versus a GnRH-agonist short protocol for ovarian stimulation in patients referred for IVF. Facts, views & vision in ObGyn, 4(2), 82-7.
Gordts, S, et al. "A prospective randomised study comparing a GnRH-antagonist versus a GnRH-agonist short protocol for ovarian stimulation in patients referred for IVF." Facts, views & vision in ObGyn vol. 4,2 (2012): 82-7.
Gordts S, Van Turnhout C, Campo R, Puttemans P, Valkenburg M, Gordts S. A prospective randomised study comparing a GnRH-antagonist versus a GnRH-agonist short protocol for ovarian stimulation in patients referred for IVF. Facts Views Vis Obgyn. 2012;4(2):82-7. PMID: 24753894; PMCID: PMC3987498.
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Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults.

Clinical & translational immunology

Kavian N, Hachim A, Li AP, Cohen CA, Chin AW, Poon LL, Fang VJ, Leung NH, Cowling BJ, Valkenburg SA.
PMID: 32025302
Clin Transl Immunology. 2020 Feb 03;9(2):e1107. doi: 10.1002/cti2.1107. eCollection 2020.

OBJECTIVES: Enhanced inactivated influenza vaccines (eIIV) aim to increase immunogenicity and protection compared with the widely used standard IIV (S-IIV).METHODS: We tested four vaccines in parallel, FluZone high dose, FluBlok and FluAd versus S-IIV in a randomised controlled trial...

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Kavian N, Hachim A, Li AP, et al. Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults. Clin Transl Immunology. 2020;9(2):e1107doi: 10.1002/cti2.1107.
Kavian, N., Hachim, A., Li, A. P., Cohen, C. A., Chin, A. W., Poon, L. L., Fang, V. J., Leung, N. H., Cowling, B. J., & Valkenburg, S. A. (2020). Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults. Clinical & translational immunology, 9(2), e1107. https://doi.org/10.1002/cti2.1107
Kavian, Niloufar, et al. "Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults." Clinical & translational immunology vol. 9,2 (2020): e1107. doi: https://doi.org/10.1002/cti2.1107
Kavian N, Hachim A, Li AP, Cohen CA, Chin AW, Poon LL, Fang VJ, Leung NH, Cowling BJ, Valkenburg SA. Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults. Clin Transl Immunology. 2020 Feb 03;9(2):e1107. doi: 10.1002/cti2.1107. eCollection 2020. PMID: 32025302; PMCID: PMC6997034.
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