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Showing 7117 to 7126 of 7126 entries
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Blind Image Restoration Enhances Digital Autoradiographic Imaging of Radiopharmaceutical Tissue Distribution.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Lu P, Benabdallah N, Jiang W, Simons BW, Zhang H, Hobbs RF, Ulmert D, Baumann B, Pachynski RK, Jha AK, Thorek DL.
PMID: 34385337
J Nucl Med. 2021 Aug 12; doi: 10.2967/jnumed.121.262270. Epub 2021 Aug 12.

Digital autoradiography (DAR) is a powerful tool to quantitatively determine the distribution of a radiopharmaceutical within a tissue section and is widely used in drug discovery and development. However, the low image resolution and significant background noise can result...

Combinatorial immunotherapy induces tumor-infiltrating CD8.

Journal for immunotherapy of cancer

Van Braeckel-Budimir N, Dolina JS, Wei J, Wang X, Chen SH, Santiago P, Tu G, Micci L, Al-Khami AA, Pfister S, Ram S, Sundar P, Thomas G, Long H, Yang W, Potluri S, Salek-Ardakani S.
PMID: 34903555
J Immunother Cancer. 2021 Dec;9(12). doi: 10.1136/jitc-2021-003614.

BACKGROUND: Programmed death (ligand) 1 (PD-(L)1) blockade and OX40/4-1BB costimulation have been separately evaluated in the clinic to elicit potent antitumor T cell responses. The precise mechanisms underlying single agent activity are incompletely understood. It also remains unclear if...

Preparation of SnO2 nanoparticles by hard template method for high selectivity gas sensors.

Journal of nanoscience and nanotechnology

Zhang H, Wang L, Tan Z, Li Z, Ding G, Jiao Z, Gu P.
PMID: 22409048
J Nanosci Nanotechnol. 2011 Dec;11(12):11023-7. doi: 10.1166/jnn.2011.4008.

In this paper, SnO2 nanoparticles were synthesized by the impregnation method with SnCl2 x 2H2O as the inorganic precursor and mesoporous silica MCM-41 as the hard template. The physical and chemical properties of the products were characterized by X-ray...

A .

Biology open

Thompson M, Sarabia Feria N, Yoshioka A, Tu E, Civitci F, Estes S, Wagner JT.
PMID: 33685856
Biol Open. 2021 Mar 26;10(3). doi: 10.1242/bio.057398.

Current methods for non-invasive prostate cancer (PrCa) detection have a high false-positive rate and often result in unnecessary biopsies. Previous work has suggested that urinary volatile organic compound (VOC) biomarkers may be able to distinguish PrCa cases from benign...

Magneto-Based Synergetic Therapy for Implant-Associated Infections via Biofilm Disruption and Innate Immunity Regulation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Wang J, Wang L, Pan J, Zhao J, Tang J, Jiang D, Hu P, Jia W, Shi J.
PMID: 33747747
Adv Sci (Weinh). 2021 Jan 31;8(6):2004010. doi: 10.1002/advs.202004010. eCollection 2021 Mar.

Implant-associated infections (IAIs) are a common cause of orthopedic surgery failure due to microbial biofilm-induced antibiotic-resistance and innate immune inactivation. Thus, the destruction of microbial biofilm plays a key role in reducing IAIs. Herein, first, a magneto-based synergetic therapy...

An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo.

Cancer letters

Xing Y, Guo W, Wu M, Xie J, Huang D, Hu P, Zhou M, Zhang L, Zhang Q, Wang P, Wang X, Wang G, Wu H, Zhou C, Chen Y, Liu M, Yi Z, Sun Z.
PMID: 34990752
Cancer Lett. 2022 Jan 04;529:100-111. doi: 10.1016/j.canlet.2021.12.035. Epub 2022 Jan 04.

The transcription factor B cell lymphoma 6 (BCL6) is an oncogenic driver of diffuse large B cell lymphoma (DLBCL) and mediates lymphomagenesis through transcriptional repression of its target genes by recruiting corepressors to its N-terminal broad-complex/tramtrack/bric-a-brac (BTB) domain. Blocking...

The Efficacy of Ramucirumab in the Treatment of Gastric or Gastroesophageal Junction Cancer: A Meta-Analysis of RCTs.

Gastroenterology research and practice

Yang H, Zhou Y, Wang L, Gu T, Lv M, Sun J, Tu C, He J.
PMID: 33679971
Gastroenterol Res Pract. 2021 Feb 22;2021:8960315. doi: 10.1155/2021/8960315. eCollection 2021.

Five electronic databases were searched for eligible records. Outcomes were presented and analyzed according to the objective response rate (ORR), progression-free survival (PFS) rate, and overall survival (OS) rate. Five records involving 2,024 participants were included in the study....

Facile and Controllable Preparation of Poly(St-.

Materials (Basel, Switzerland)

Chen T, Sang Y, Zhou Y, Ji L, Han X, Hu P, Miao P, Gao J, Zhao Y.
PMID: 34885545
Materials (Basel). 2021 Dec 02;14(23). doi: 10.3390/ma14237390.

Hydraulic fracturing is an important technology for the exploitation of unconventional oil or gas reservoirs. In order to increase the production of oil or gas, ultra-lightweight proppants with a high compressive strength are highly desirable in hydraulic fracture systems....

Comprehensive lipidomics analysis of the lipids in hazelnut oil during storage.

Food chemistry

Sun J, Hu P, Lyu C, Tian J, Meng X, Tan H, Dong W.
PMID: 35032812
Food Chem. 2022 Jan 05;378:132050. doi: 10.1016/j.foodchem.2022.132050. Epub 2022 Jan 05.

Although hazelnut oil is is nutritious, it is easily oxidized during storage. Thus far, changes in lipids during storage have not been comprehensively analyzed. Here, we used ultra-high liquid chromatography tandem quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) to dynamically monitor...

Simultaneous quantification of eleven short-chain fatty acids by derivatization and solid phase microextraction - Gas chromatography tandem mass spectrometry.

Journal of chromatography. A

Fu Z, Jia Q, Zhang H, Kang L, Sun X, Zhang M, Wang Y, Hu P.
PMID: 34879311
J Chromatogr A. 2021 Nov 11;1661:462680. doi: 10.1016/j.chroma.2021.462680. Epub 2021 Nov 11.

As metabolites of the gut microbiome, short-chain fatty acids (SCFAs) played an important role in the diagnosis of the metabolic diseases. Because of the high polarity, high volatility and complex matrix of biological samples, the highly sensitive, selective and...

Showing 7117 to 7126 of 7126 entries