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Showing 37 to 48 of 136 entries
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aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.

Proceedings of the National Academy of Sciences of the United States of America

Molinar-Inglis O, Birch CA, Nicholas D, Orduña-Castillo L, Cisneros-Aguirre M, Patwardhan A, Chen B, Grimsey NJ, Coronel LJ, Lin H, Gomez Menzies PK, Lawson MA, Patel HH, Trejo J.
PMID: 34873055
Proc Natl Acad Sci U S A. 2021 Dec 07;118(49). doi: 10.1073/pnas.2106623118.

Endothelial dysfunction is associated with vascular disease and results in disruption of endothelial barrier function and increased sensitivity to apoptosis. Currently, there are limited treatments for improving endothelial dysfunction. Activated protein C (aPC), a promising therapeutic, signals via protease-activated...

Adopting a multidisciplinary telemedicine intervention for fall prevention in Parkinson's disease. Protocol for a longitudinal, randomized clinical trial.

PloS one

Cubo E, Garcia-Bustillo A, Arnaiz-Gonzalez A, Ramirez-Sanz JM, Garrido-Labrador JL, Valiñas F, Allende M, Gonzalez-Bernal JJ, Gonzalez-Santos J, Diez-Pastor JF, Jahouh M, Arribas J, Trejo J.
PMID: 34932580
PLoS One. 2021 Dec 21;16(12):e0260889. doi: 10.1371/journal.pone.0260889. eCollection 2021.

BACKGROUND: Approximately 40-70% of people with Parkinson's disease (PD) fall each year, causing decreased activity levels and quality of life. Current fall-prevention strategies include the use of pharmacological and non-pharmacological therapies. To increase the accessibility of this vulnerable population,...

Healthcare resource utilization and costs in pediatric pulmonary arterial hypertension in a third-level hospital in Mexico.

Journal of comparative effectiveness research

García-Aguilar H, Vázquez SG, Trejo KS, Juárez YE, Juárez Vásquez KI, Sarmiento Sánchez ES, Molina HS.
PMID: 34585624
J Comp Eff Res. 2021 Nov;10(16):1251-1257. doi: 10.2217/cer-2021-0128. Epub 2021 Sep 29.

No abstract available.

Human influenza virus challenge identifies cellular correlates of protection for oral vaccination.

Cell host & microbe

McIlwain DR, Chen H, Rahil Z, Bidoki NH, Jiang S, Bjornson Z, Kolhatkar NS, Martinez CJ, Gaudillière B, Hedou J, Mukherjee N, Schürch CM, Trejo A, Affrime M, Bock B, Kim K, Liebowitz D, Aghaeepour N, Tucker SN, Nolan GP.
PMID: 34784508
Cell Host Microbe. 2021 Dec 08;29(12):1828-1837.e5. doi: 10.1016/j.chom.2021.10.009. Epub 2021 Nov 15.

Developing new influenza vaccines with improved performance and easier administration routes hinges on defining correlates of protection. Vaccine-elicited cellular correlates of protection for influenza in humans have not yet been demonstrated. A phase-2 double-blind randomized placebo and active (inactivated...

Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption.

Science signaling

Rada CC, Mejia-Pena H, Grimsey NJ, Canto Cordova I, Olson J, Wozniak JM, Gonzalez DJ, Nizet V, Trejo J.
PMID: 34516752
Sci Signal. 2021 Aug 31;14(698):eabc1044. doi: 10.1126/scisignal.abc1044. Epub 2021 Aug 31.

[Figure: see text].

Age-specific burden of cervical cancer associated with HIV: A global analysis with a focus on sub-Saharan Africa.

International journal of cancer

Ibrahim Khalil A, Mpunga T, Wei F, Baussano I, de Martel C, Bray F, Stelzle D, Dryden-Peterson S, Jaquet A, Horner MJ, Awolude OA, Trejo MJ, Mudini W, Soliman AS, Sengayi-Muchengeti M, Coghill AE, van Aardt MC, De Vuyst H, Hawes SE, Broutet N, Dalal S, Clifford GM.
PMID: 34626498
Int J Cancer. 2021 Oct 09; doi: 10.1002/ijc.33841. Epub 2021 Oct 09.

HIV substantially worsens human papillomavirus (HPV) carcinogenicity and contributes to an important population excess of cervical cancer, particularly in sub-Saharan Africa (SSA). We estimated HIV- and age-stratified cervical cancer burden at a country, regional and global level in 2020....

5-HT.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi

Da Costa Guevara D, Trejo E.
PMID: 34980821
J Smooth Muscle Res. 2021;57:79-93. doi: 10.1540/jsmr.57.79.

BACKGROUND: Serotonin (5-hydroxytryptamine; 5-HT) performs a variety of functions in the body including the modulation of muscle tone in respiratory airways. Several studies indicate a possible role of 5-HT in the pathophysiology of bronchial hyperresponsiveness. However, the receptors and...

Predictors of SARS-CoV-2 Infection in Youth at a Large, Urban Healthcare Center in California, March-September 2020.

Frontiers in pediatrics

Newhouse CN, Saleh T, Fuller T, Kerin T, Cambou MC, Swayze EJ, Le C, Seo W, Trejo M, Garner OB, Chandrasekaran S, Nielsen-Saines K.
PMID: 34869107
Front Pediatr. 2021 Nov 17;9:752247. doi: 10.3389/fped.2021.752247. eCollection 2021.

No abstract available.

Enteric Pathogens and Reactive Arthritis: Systematic Review and Meta-Analyses of Pathogen-Associated Reactive Arthritis.

Foodborne pathogens and disease

Pogreba-Brown K, Austhof E, Tang X, Trejo MJ, Owusu-Dommey A, Boyd K, Armstrong A, Schaefer K, Bazaco MC, Batz M, Riddle M, Porter C.
PMID: 34255548
Foodborne Pathog Dis. 2021 Sep;18(9):627-639. doi: 10.1089/fpd.2020.2910. Epub 2021 Jul 13.

The objective of this systematic review and meta-analysis was to estimate the proportion of postinfectious reactive arthritis (ReA) after bacterial enteric infection from one of four selected pathogens. We collected studies from PubMed, Web of Science, and Embase, which...

Impact of introducing cell-free DNA screening into clinical care on first trimester ultrasound.

Prenatal diagnosis

Doulaveris G, Igel CM, Trejo FE, Fiorentino D, Rabin-Havt S, Klugman S, Dar P.
PMID: 34989002
Prenat Diagn. 2022 Jan 05; doi: 10.1002/pd.6086. Epub 2022 Jan 05.

OBJECTIVE: First-trimester ultrasound is an important component of prenatal care. We investigated the impact of introducing cell-free DNA (cfDNA) aneuploidy screening into routine care, on performance of first-trimester ultrasound.METHODS: Retrospective study of patients who had prenatal care at a...

aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.

Proceedings of the National Academy of Sciences of the United States of America

Molinar-Inglis O, Birch CA, Nicholas D, Orduña-Castillo L, Cisneros-Aguirre M, Patwardhan A, Chen B, Grimsey NJ, Coronel LJ, Lin H, Gomez Menzies PK, Lawson MA, Patel HH, Trejo J.
PMID: 34873055
Proc Natl Acad Sci U S A. 2021 Dec 07;118(49). doi: 10.1073/pnas.2106623118.

Endothelial dysfunction is associated with vascular disease and results in disruption of endothelial barrier function and increased sensitivity to apoptosis. Currently, there are limited treatments for improving endothelial dysfunction. Activated protein C (aPC), a promising therapeutic, signals via protease-activated...

Primary Angioplasty in a Single Coronary Artery.

Revista espanola de cardiologia (English ed.)

Trejo B, García P, Rumiz E.
PMID: 27876466
Rev Esp Cardiol (Engl Ed). 2017 Jul;70(7):590. doi: 10.1016/j.rec.2016.10.007. Epub 2016 Nov 19.

No abstract available.

Showing 37 to 48 of 136 entries