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Synthesis of Hybrid Phosphorated Indenoquinolines and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative agents.

Bioorganic & medicinal chemistry letters

Fuertes M, Selas A, Trejo A, Knudsen BR, Palacios F, Alonso C.
PMID: 34952177
Bioorg Med Chem Lett. 2021 Dec 21;128517. doi: 10.1016/j.bmcl.2021.128517. Epub 2021 Dec 21.

This work describes the first synthesis of diethyl 6,6a,7,11b-tetrahydro-5H-indeno[2,1-c]quinolinylphosphonates 5, diethyl 7H-indeno[2,1-c]quinolinylphosphonates 6 and diethyl 7-oxo-7H-indeno[2,1-c]quinolinylphosphonates 7, which were prepared in good to high overall yields. The synthetic route involves a multicomponent reaction of 2-phosphonateaniline, aldehydes and indene as...

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Fuertes M, Selas A, Trejo A, et al. Synthesis of Hybrid Phosphorated Indenoquinolines and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative agents. Bioorg Med Chem Lett. 2021;128517doi: 10.1016/j.bmcl.2021.128517.
Fuertes, M., Selas, A., Trejo, A., Knudsen, B. R., Palacios, F., & Alonso, C. (2021). Synthesis of Hybrid Phosphorated Indenoquinolines and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative agents. Bioorganic & medicinal chemistry letters, 128517. https://doi.org/10.1016/j.bmcl.2021.128517
Fuertes, María, et al. "Synthesis of Hybrid Phosphorated Indenoquinolines and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative agents." Bioorganic & medicinal chemistry letters vol. (2021): 128517. doi: https://doi.org/10.1016/j.bmcl.2021.128517
Fuertes M, Selas A, Trejo A, Knudsen BR, Palacios F, Alonso C. Synthesis of Hybrid Phosphorated Indenoquinolines and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative agents. Bioorg Med Chem Lett. 2021 Dec 21;128517. doi: 10.1016/j.bmcl.2021.128517. Epub 2021 Dec 21. PMID: 34952177.
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Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Trejo MJ, Soliman AS, Chen Y, Kalima M, Chuba A, Chama E, Mwaba CK, Banda L, Lishimpi K.
PMID: 34121186
Int J Gynaecol Obstet. 2021 Jun 14; doi: 10.1002/ijgo.13784. Epub 2021 Jun 14.

OBJECTIVE: To examine the association between the duration of HIV infection and the stage of cervical cancer in Lusaka, Zambia.METHODS: This retrospective case-case study included 1583 cervical cancer patients from the Cancer Diseases Hospital in Lusaka, Zambia. A sub-population...

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Trejo MJ, Soliman AS, Chen Y, et al. Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia. Int J Gynaecol Obstet. 2021;doi: 10.1002/ijgo.13784.
Trejo, M. J., Soliman, A. S., Chen, Y., Kalima, M., Chuba, A., Chama, E., Mwaba, C. K., Banda, L., & Lishimpi, K. (2021). Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, . https://doi.org/10.1002/ijgo.13784
Trejo, Mario Jesus, et al. "Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia." International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics vol. (2021). doi: https://doi.org/10.1002/ijgo.13784
Trejo MJ, Soliman AS, Chen Y, Kalima M, Chuba A, Chama E, Mwaba CK, Banda L, Lishimpi K. Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia. Int J Gynaecol Obstet. 2021 Jun 14; doi: 10.1002/ijgo.13784. Epub 2021 Jun 14. PMID: 34121186.
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Human influenza virus challenge identifies cellular correlates of protection for oral vaccination.

Cell host & microbe

McIlwain DR, Chen H, Rahil Z, Bidoki NH, Jiang S, Bjornson Z, Kolhatkar NS, Martinez CJ, Gaudillière B, Hedou J, Mukherjee N, Schürch CM, Trejo A, Affrime M, Bock B, Kim K, Liebowitz D, Aghaeepour N, Tucker SN, Nolan GP.
PMID: 34784508
Cell Host Microbe. 2021 Dec 08;29(12):1828-1837.e5. doi: 10.1016/j.chom.2021.10.009. Epub 2021 Nov 15.

Developing new influenza vaccines with improved performance and easier administration routes hinges on defining correlates of protection. Vaccine-elicited cellular correlates of protection for influenza in humans have not yet been demonstrated. A phase-2 double-blind randomized placebo and active (inactivated...

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McIlwain DR, Chen H, Rahil Z, et al. Human influenza virus challenge identifies cellular correlates of protection for oral vaccination. Cell Host Microbe. 2021;29(12):1828-1837.e5doi: 10.1016/j.chom.2021.10.009.
McIlwain, D. R., Chen, H., Rahil, Z., Bidoki, N. H., Jiang, S., Bjornson, Z., Kolhatkar, N. S., Martinez, C. J., Gaudillière, B., Hedou, J., Mukherjee, N., Schürch, C. M., Trejo, A., Affrime, M., Bock, B., Kim, K., Liebowitz, D., Aghaeepour, N., Tucker, S. N., & Nolan, G. P. (2021). Human influenza virus challenge identifies cellular correlates of protection for oral vaccination. Cell host & microbe, 29(12), 1828-1837.e5. https://doi.org/10.1016/j.chom.2021.10.009
McIlwain, David R, et al. "Human influenza virus challenge identifies cellular correlates of protection for oral vaccination." Cell host & microbe vol. 29,12 (2021): 1828-1837.e5. doi: https://doi.org/10.1016/j.chom.2021.10.009
McIlwain DR, Chen H, Rahil Z, Bidoki NH, Jiang S, Bjornson Z, Kolhatkar NS, Martinez CJ, Gaudillière B, Hedou J, Mukherjee N, Schürch CM, Trejo A, Affrime M, Bock B, Kim K, Liebowitz D, Aghaeepour N, Tucker SN, Nolan GP. Human influenza virus challenge identifies cellular correlates of protection for oral vaccination. Cell Host Microbe. 2021 Dec 08;29(12):1828-1837.e5. doi: 10.1016/j.chom.2021.10.009. Epub 2021 Nov 15. PMID: 34784508; PMCID: PMC8665113.
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Risk factors for failure of limb salvage among veterans with foot ulcers.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons

Trejo J, Ryan E, Khan F, Iannuzzi N, Chansky H, Lack WD.
PMID: 34172392
Foot Ankle Surg. 2021 Jun 21; doi: 10.1016/j.fas.2021.06.003. Epub 2021 Jun 21.

BACKGROUND: There is limited available information to guide early discussions involving limb salvage for patients with non-traumatic foot ulcers. We hypothesized patient, wound and treatment factors identifiable at initial operative treatment would be associated with failure of attempted limb...

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Trejo J, Ryan E, Khan F, et al. Risk factors for failure of limb salvage among veterans with foot ulcers. Foot Ankle Surg. 2021;doi: 10.1016/j.fas.2021.06.003.
Trejo, J., Ryan, E., Khan, F., Iannuzzi, N., Chansky, H., & Lack, W. D. (2021). Risk factors for failure of limb salvage among veterans with foot ulcers. Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, . https://doi.org/10.1016/j.fas.2021.06.003
Trejo, Jonathan, et al. "Risk factors for failure of limb salvage among veterans with foot ulcers." Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons vol. (2021). doi: https://doi.org/10.1016/j.fas.2021.06.003
Trejo J, Ryan E, Khan F, Iannuzzi N, Chansky H, Lack WD. Risk factors for failure of limb salvage among veterans with foot ulcers. Foot Ankle Surg. 2021 Jun 21; doi: 10.1016/j.fas.2021.06.003. Epub 2021 Jun 21. PMID: 34172392.
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Computational simulation of the effects of oxygen on the electronic states of hydrogenated 3C-porous SiC.

Nanoscale research letters

Trejo A, Calvino M, Ramos E, Cruz-Irisson M.
PMID: 22913486
Nanoscale Res Lett. 2012 Aug 22;7(1):471. doi: 10.1186/1556-276X-7-471.

A computational study of the dependence of the electronic band structure and density of states on the chemical surface passivation of cubic porous silicon carbide (pSiC) was performed using ab initio density functional theory and the supercell method. The...

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Trejo A, Calvino M, Ramos E, et al. Computational simulation of the effects of oxygen on the electronic states of hydrogenated 3C-porous SiC. Nanoscale Res Lett. 2012;7(1):471doi: 10.1186/1556-276X-7-471.
Trejo, A., Calvino, M., Ramos, E., & Cruz-Irisson, M. (2012). Computational simulation of the effects of oxygen on the electronic states of hydrogenated 3C-porous SiC. Nanoscale research letters, 7(1), 471. https://doi.org/10.1186/1556-276X-7-471
Trejo, Alejandro, et al. "Computational simulation of the effects of oxygen on the electronic states of hydrogenated 3C-porous SiC." Nanoscale research letters vol. 7,1 (2012): 471. doi: https://doi.org/10.1186/1556-276X-7-471
Trejo A, Calvino M, Ramos E, Cruz-Irisson M. Computational simulation of the effects of oxygen on the electronic states of hydrogenated 3C-porous SiC. Nanoscale Res Lett. 2012 Aug 22;7(1):471. doi: 10.1186/1556-276X-7-471. PMID: 22913486; PMCID: PMC3462725.
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Carbon monoxide sensing properties of B-, Al- and Ga-doped Si nanowires.

Nanotechnology

de Santiago F, Trejo A, Miranda A, Salazar F, Carvajal E, Pérez LA, Cruz-Irisson M.
PMID: 29480169
Nanotechnology. 2018 May 18;29(20):204001. doi: 10.1088/1361-6528/aab237. Epub 2018 Feb 26.

Silicon nanowires (SiNWs) are considered as potential chemical sensors due to their large surface-to-volume ratio and their possible integration into arrays for nanotechnological applications. Detection of harmful gases like CO has been experimentally demonstrated, however, the influence of doping...

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de Santiago F, Trejo A, Miranda A, et al. Carbon monoxide sensing properties of B-, Al- and Ga-doped Si nanowires. Nanotechnology. 2018;29(20):204001doi: 10.1088/1361-6528/aab237.
de Santiago, F., Trejo, A., Miranda, A., Salazar, F., Carvajal, E., Pérez, L. A., & Cruz-Irisson, M. (2018). Carbon monoxide sensing properties of B-, Al- and Ga-doped Si nanowires. Nanotechnology, 29(20), 204001. https://doi.org/10.1088/1361-6528/aab237
de Santiago, F, et al. "Carbon monoxide sensing properties of B-, Al- and Ga-doped Si nanowires." Nanotechnology vol. 29,20 (2018): 204001. doi: https://doi.org/10.1088/1361-6528/aab237
de Santiago F, Trejo A, Miranda A, Salazar F, Carvajal E, Pérez LA, Cruz-Irisson M. Carbon monoxide sensing properties of B-, Al- and Ga-doped Si nanowires. Nanotechnology. 2018 May 18;29(20):204001. doi: 10.1088/1361-6528/aab237. Epub 2018 Feb 26. PMID: 29480169.
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Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis.

NPJ breast cancer

Trejo CL, Luna G, Dravis C, Spike BT, Wahl GM.
PMID: 28649656
NPJ Breast Cancer. 2017 Apr 24;3:16. doi: 10.1038/s41523-017-0018-6. eCollection 2017.

The search for the bipotent mammary stem cells that drive mammary development requires markers to enable their prospective isolation. There is general agreement that bipotent mouse mammary stem cells are abundant in late fetal development, but their existence in...

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Trejo CL, Luna G, Dravis C, et al. Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis. NPJ Breast Cancer. 2017;3:16doi: 10.1038/s41523-017-0018-6.
Trejo, C. L., Luna, G., Dravis, C., Spike, B. T., & Wahl, G. M. (2017). Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis. NPJ breast cancer, 316. https://doi.org/10.1038/s41523-017-0018-6
Trejo, Christy L, et al. "Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis." NPJ breast cancer vol. 3 (2017): 16. doi: https://doi.org/10.1038/s41523-017-0018-6
Trejo CL, Luna G, Dravis C, Spike BT, Wahl GM. Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis. NPJ Breast Cancer. 2017 Apr 24;3:16. doi: 10.1038/s41523-017-0018-6. eCollection 2017. PMID: 28649656; PMCID: PMC5460261.
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ALD Zn(O,S) Thin Films' Interfacial Chemical and Structural Configuration Probed by XAS.

ACS applied materials & interfaces

Dadlani AL, Acharya S, Trejo O, Prinz FB, Torgersen J.
PMID: 27223620
ACS Appl Mater Interfaces. 2016 Jun 15;8(23):14323-7. doi: 10.1021/acsami.6b04000. Epub 2016 May 31.

The ability to precisely control interfaces of atomic layer deposited (ALD) zinc oxysulfide (Zn(O,S)) buffer layers to other layers allows precise tuning of solar cell performance. The O K- and S K-edge X-ray absorption near edge structure (XANES) of...

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Dadlani AL, Acharya S, Trejo O, et al. ALD Zn(O,S) Thin Films' Interfacial Chemical and Structural Configuration Probed by XAS. ACS Appl Mater Interfaces. 2016;8(23):14323-7doi: 10.1021/acsami.6b04000.
Dadlani, A. L., Acharya, S., Trejo, O., Prinz, F. B., & Torgersen, J. (2016). ALD Zn(O,S) Thin Films' Interfacial Chemical and Structural Configuration Probed by XAS. ACS applied materials & interfaces, 8(23), 14323-7. https://doi.org/10.1021/acsami.6b04000
Dadlani, Anup L, et al. "ALD Zn(O,S) Thin Films' Interfacial Chemical and Structural Configuration Probed by XAS." ACS applied materials & interfaces vol. 8,23 (2016): 14323-7. doi: https://doi.org/10.1021/acsami.6b04000
Dadlani AL, Acharya S, Trejo O, Prinz FB, Torgersen J. ALD Zn(O,S) Thin Films' Interfacial Chemical and Structural Configuration Probed by XAS. ACS Appl Mater Interfaces. 2016 Jun 15;8(23):14323-7. doi: 10.1021/acsami.6b04000. Epub 2016 May 31. PMID: 27223620; PMCID: PMC4911619.
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Band-gap engineering of halogenated silicon nanowires through molecular doping.

Journal of molecular modeling

de Santiago F, Trejo A, Miranda A, Carvajal E, Pérez LA, Cruz-Irisson M.
PMID: 29035419
J Mol Model. 2017 Oct 16;23(11):314. doi: 10.1007/s00894-017-3484-8.

In this work, we address the effects of molecular doping on the electronic properties of fluorinated and chlorinated silicon nanowires (SiNWs), in comparison with those corresponding to hydrogen-passivated SiNWs. Adsorption of n-type dopant molecules on hydrogenated and halogenated SiNWs...

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de Santiago F, Trejo A, Miranda A, et al. Band-gap engineering of halogenated silicon nanowires through molecular doping. J Mol Model. 2017;23(11):314doi: 10.1007/s00894-017-3484-8.
de Santiago, F., Trejo, A., Miranda, A., Carvajal, E., Pérez, L. A., & Cruz-Irisson, M. (2017). Band-gap engineering of halogenated silicon nanowires through molecular doping. Journal of molecular modeling, 23(11), 314. https://doi.org/10.1007/s00894-017-3484-8
de Santiago, Francisco, et al. "Band-gap engineering of halogenated silicon nanowires through molecular doping." Journal of molecular modeling vol. 23,11 (2017): 314. doi: https://doi.org/10.1007/s00894-017-3484-8
de Santiago F, Trejo A, Miranda A, Carvajal E, Pérez LA, Cruz-Irisson M. Band-gap engineering of halogenated silicon nanowires through molecular doping. J Mol Model. 2017 Oct 16;23(11):314. doi: 10.1007/s00894-017-3484-8. PMID: 29035419.
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Retroperitoneal epithelioid sarcoma: A case report.

World journal of gastrointestinal endoscopy

Coronado JA, Chávez MÁ, Manrique MA, Cerna J, Trejo AL.
PMID: 29290913
World J Gastrointest Endosc. 2017 Dec 16;9(12):579-582. doi: 10.4253/wjge.v9.i12.579.

Epithelioid sarcoma (ES), a mesenchymatous malign neoformation, is often diagnosed in later stages and associated with high recurrence index, metastasis and mortality. We report a case of a 65 years old male, with history of abdominal pain and upper...

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Coronado JA, Chávez MÁ, Manrique MA, et al. Retroperitoneal epithelioid sarcoma: A case report. World J Gastrointest Endosc. 2017;9(12):579-582doi: 10.4253/wjge.v9.i12.579.
Coronado, J. A., Chávez, M. �. �., Manrique, M. A., Cerna, J., & Trejo, A. L. (2017). Retroperitoneal epithelioid sarcoma: A case report. World journal of gastrointestinal endoscopy, 9(12), 579-582. https://doi.org/10.4253/wjge.v9.i12.579
Coronado, José A, et al. "Retroperitoneal epithelioid sarcoma: A case report." World journal of gastrointestinal endoscopy vol. 9,12 (2017): 579-582. doi: https://doi.org/10.4253/wjge.v9.i12.579
Coronado JA, Chávez MÁ, Manrique MA, Cerna J, Trejo AL. Retroperitoneal epithelioid sarcoma: A case report. World J Gastrointest Endosc. 2017 Dec 16;9(12):579-582. doi: 10.4253/wjge.v9.i12.579. PMID: 29290913; PMCID: PMC5740103.
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Single Cell Multi-Omics Technology: Methodology and Application.

Frontiers in cell and developmental biology

Hu Y, An Q, Sheu K, Trejo B, Fan S, Guo Y.
PMID: 29732369
Front Cell Dev Biol. 2018 Apr 20;6:28. doi: 10.3389/fcell.2018.00028. eCollection 2018.

In the era of precision medicine, multi-omics approaches enable the integration of data from diverse omics platforms, providing multi-faceted insight into the interrelation of these omics layers on disease processes. Single cell sequencing technology can dissect the genotypic and...

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Hu Y, An Q, Sheu K, et al. Single Cell Multi-Omics Technology: Methodology and Application. Front Cell Dev Biol. 2018;6:28doi: 10.3389/fcell.2018.00028.
Hu, Y., An, Q., Sheu, K., Trejo, B., Fan, S., & Guo, Y. (2018). Single Cell Multi-Omics Technology: Methodology and Application. Frontiers in cell and developmental biology, 628. https://doi.org/10.3389/fcell.2018.00028
Hu, Youjin, et al. "Single Cell Multi-Omics Technology: Methodology and Application." Frontiers in cell and developmental biology vol. 6 (2018): 28. doi: https://doi.org/10.3389/fcell.2018.00028
Hu Y, An Q, Sheu K, Trejo B, Fan S, Guo Y. Single Cell Multi-Omics Technology: Methodology and Application. Front Cell Dev Biol. 2018 Apr 20;6:28. doi: 10.3389/fcell.2018.00028. eCollection 2018. PMID: 29732369; PMCID: PMC5919954.
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Mining IP to Domain Name Interactions to Detect DNS Flood Attacks on Recursive DNS Servers.

Sensors (Basel, Switzerland)

Alonso R, Monroy R, Trejo LA.
PMID: 27548169
Sensors (Basel). 2016 Aug 17;16(8). doi: 10.3390/s16081311.

The Domain Name System (DNS) is a critical infrastructure of any network, and, not surprisingly a common target of cybercrime. There are numerous works that analyse higher level DNS traffic to detect anomalies in the DNS or any other...

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Alonso R, Monroy R, Trejo LA. Mining IP to Domain Name Interactions to Detect DNS Flood Attacks on Recursive DNS Servers. Sensors (Basel). 2016;16(8)doi: 10.3390/s16081311.
Alonso, R., Monroy, R., & Trejo, L. A. (2016). Mining IP to Domain Name Interactions to Detect DNS Flood Attacks on Recursive DNS Servers. Sensors (Basel, Switzerland), 16(8), . https://doi.org/10.3390/s16081311
Alonso, Roberto, et al. "Mining IP to Domain Name Interactions to Detect DNS Flood Attacks on Recursive DNS Servers." Sensors (Basel, Switzerland) vol. 16,8 (2016). doi: https://doi.org/10.3390/s16081311
Alonso R, Monroy R, Trejo LA. Mining IP to Domain Name Interactions to Detect DNS Flood Attacks on Recursive DNS Servers. Sensors (Basel). 2016 Aug 17;16(8). doi: 10.3390/s16081311. PMID: 27548169; PMCID: PMC5017476.
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Showing 13 to 24 of 136 entries