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Showing 1501 to 1511 of 1511 entries
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Interhospital failure to rescue after coronary artery bypass grafting.

The Journal of thoracic and cardiovascular surgery

Likosky DS, Strobel RJ, Wu X, Kramer RS, Hamman BL, Brevig JK, Thompson MP, Ghaferi AA, Zhang M, Lehr EJ.
PMID: 33712236
J Thorac Cardiovasc Surg. 2021 Jan 29; doi: 10.1016/j.jtcvs.2021.01.064. Epub 2021 Jan 29.

OBJECTIVE: We evaluated whether interhospital variation in mortality rates for coronary artery bypass grafting was driven by complications and failure to rescue.METHODS: An observational study was conducted among 83,747 patients undergoing isolated coronary artery bypass grafting between July 2011...

Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage.

Science immunology

Askenase MH, Goods BA, Beatty HE, Steinschneider AF, Velazquez SE, Osherov A, Landreneau MJ, Carroll SL, Tran TB, Avram VS, Drake RS, Gatter GJ, Massey JA, Karuppagounder SS, Ratan RR, Matouk CC, Sheth KN, Ziai WC, Parry-Jones AR, Awad IA, Zuccarello M, Thompson RE, Dawson J, Hanley DF, Love JC, Shalek AK, Sansing LH.
PMID: 33891558
Sci Immunol. 2021 Feb 19;6(56). doi: 10.1126/sciimmunol.abd6279. Epub 2021 Feb 19.

Opportunities to interrogate the immune responses in the injured tissue of living patients suffering from acute sterile injuries such as stroke and heart attack are limited. We leveraged a clinical trial of minimally invasive neurosurgery for patients with intracerebral...

The role of SERPIN citrullination in thrombosis.

Cell chemical biology

Tilvawala R, Nemmara VV, Reyes AC, Sorvillo N, Salinger AJ, Cherpokova D, Fukui S, Gutch S, Wagner D, Thompson PR.
PMID: 34352225
Cell Chem Biol. 2021 Dec 16;28(12):1728-1739.e5. doi: 10.1016/j.chembiol.2021.07.009. Epub 2021 Aug 04.

Aberrant protein citrullination is associated with many pathologies; however, the specific effects of this modification remain unknown. We have previously demonstrated that serine protease inhibitors (SERPINs) are highly citrullinated in rheumatoid arthritis (RA) patients. These citrullinated SERPINs include antithrombin,...

Exceptional Packing Density of Ammonia in a Dual-Functionalized Metal-Organic Framework.

Journal of the American Chemical Society

Marsh C, Han X, Li J, Lu Z, Argent SP, da Silva I, Cheng Y, Daemen LL, Ramirez-Cuesta AJ, Thompson SP, Blake AJ, Yang S, Schröder M.
PMID: 33885294
J Am Chem Soc. 2021 May 05;143(17):6586-6592. doi: 10.1021/jacs.1c01749. Epub 2021 Apr 22.

We report the reversible adsorption of ammonia (NH

Ibrutinib induces durable remissions in treatment-naïve patients with CLL and 17p deletion and/or TP53 mutations.

Blood

Sivina M, Kim E, Wierda WG, Ferrajoli A, Jain N, Thompson P, Kantarjian H, Keating M, Burger JA.
PMID: 34521099
Blood. 2021 Dec 16;138(24):2589-2592. doi: 10.1182/blood.2021012315.

No abstract available.

Prevention of Vertical Transmission of Hepatitis B Within a North Carolina Hospital System.

Clinical therapeutics

Sayre W, Thompson P.
PMID: 34593255
Clin Ther. 2021 Oct;43(10):1786-1791. doi: 10.1016/j.clinthera.2021.08.012. Epub 2021 Sep 27.

PURPOSE: Hepatitis B virus (HBV) is a major contributor to liver-related disease globally. Vertical transmission of hepatitis B can lead to devastating outcomes in neonates, making prevention of transmission essential. Fortunately, prevention is possible with evidence-based interventions via guidelines...

Making academia environmentally sustainable: a student perspective.

The Lancet. Planetary health

Roca-Barcelo A, Gaines AM, Sheehan A, Thompson R, Chamberlain RC, Bos B, Belcher RN.
PMID: 34508678
Lancet Planet Health. 2021 Sep;5(9):e576-e577. doi: 10.1016/S2542-5196(21)00199-6.

No abstract available.

One-Pot Self-Assembly of Dinuclear, Tetranuclear, and H-Bonding-Directed Polynuclear Cobalt(II), Cobalt(III), and Mixed-Valence Co(II)/Co(III) Complexes of Schiff Base Ligands with Incomplete Double Cubane Core.

Materials (Basel, Switzerland)

Tandon SS, Patel N, Bunge SD, Wang EC, Thompson R, Thompson LK.
PMID: 33260611
Materials (Basel). 2020 Nov 28;13(23). doi: 10.3390/ma13235425.

The reaction of 2,6-diformyl-4-methylphenol (DFMF) with 1-amino-2-propanol (AP) and tris(hydroxymethyl)aminomethane (THMAM) was investigated in the presence of Cobalt(II) salts, (X = ClO

Coupled microbiome analyses highlights relative functional roles of bacteria in a bivalve hatchery.

Environmental microbiome

Timmins-Schiffman E, White SJ, Thompson RE, Vadopalas B, Eudeline B, Nunn BL, Roberts SB.
PMID: 33902744
Environ Microbiome. 2021 Mar 31;16(1):7. doi: 10.1186/s40793-021-00376-z.

BACKGROUND: Microbial communities are ubiquitous throughout ecosystems and are commensal with hosts across taxonomic boundaries. Environmental and species-specific microbiomes are instrumental in maintaining ecosystem and host health, respectively. The introduction of pathogenic microbes that shift microbiome community structure can...

Relative Prognostic Significance of Positron Emission Tomography Myocardial Perfusion Imaging Markers in Cardiomyopathy.

Circulation. Cardiovascular imaging

Thomas M, Sperry BW, Peri-Okonny P, Malik AO, McGhie AI, Saeed IM, Chan PS, Spertus JA, Thompson RC, Bateman TM, Patel KK.
PMID: 34665673
Circ Cardiovasc Imaging. 2021 Oct;14(10):e012426. doi: 10.1161/CIRCIMAGING.121.012426. Epub 2021 Oct 19.

BACKGROUND: Rubidium-82 positron emission tomography myocardial perfusion imaging provides measurements of perfusion, myocardial blood flow and reserve (MBFR), and changes in left ventricular ejection fraction (LVEF) at rest and peak stress. Although all of these variables are known to...

Preparation of Underrepresented Males for Scientific Careers: A Study of the Dr. John H. Hopps Jr. Defense Research Scholars Program at Morehouse College.

Thompson RC, Monroe-White T, Xavier J, Howell C, Moore MR, Haynes JK.
UIID-AD: 3544
2016; doi: 10.1187/cbe.15-12-0263.

Equal representation within higher education science, technology, engineering, and mathematics (STEM) fields and the STEM workforce in the United States across demographically diverse populations is a long-standing challenge. This study uses two-to-one nearest- neighbor matched-comparison group design to examine...

Showing 1501 to 1511 of 1511 entries