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Showing 181 to 192 of 196 entries
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The role of cDC1s .

F1000Research

Theisen D, Murphy K.
PMID: 28184299
F1000Res. 2017 Feb 01;6:98. doi: 10.12688/f1000research.9997.1. eCollection 2017.

The cDC1 subset of classical dendritic cells is specialized for priming CD8 T cell responses through the process of cross-presentation. The molecular mechanisms of cross-presentation remain incompletely understood because of limited biochemical analysis of rare cDC1 cells, difficulty in...

The Role of Interferon in the Management of BCG Refractory Nonmuscle Invasive Bladder Cancer.

Advances in urology

Correa AF, Theisen K, Ferroni M, Maranchie JK, Hrebinko R, Davies BJ, Gingrich JR.
PMID: 26550012
Adv Urol. 2015;2015:656918. doi: 10.1155/2015/656918. Epub 2015 Oct 13.

Background. Thirty to forty percent of patients with high grade nonmuscle invasive bladder cancer (NMIBC) fail to respond to intravesical therapy with bacillus Calmette-Guerin (BCG). Interferon-α2B plus BCG has been shown to be effective in a subset of patients...

Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.

Cell reports

An D, Schneller JL, Frassetto A, Liang S, Zhu X, Park JS, Theisen M, Hong SJ, Zhou J, Rajendran R, Levy B, Howell R, Besin G, Presnyak V, Sabnis S, Murphy-Benenato KE, Kumarasinghe ES, Salerno T, Mihai C, Lukacs CM, Chandler RJ, Guey LT, Venditti CP, Martini PGV.
PMID: 30157442
Cell Rep. 2018 Aug 28;24(9):2520. doi: 10.1016/j.celrep.2018.08.049.

No abstract available.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

Benestad EEP, Olsen GF, Thesen J, Aars H, Bjørkman M.
PMID: 29411566
Tidsskr Nor Laegeforen. 2018 Feb 05;138(3). doi: 10.4045/tidsskr.18.0070. Print 2018 Feb 06.

No abstract available.

Finite element model of a below-knee amputation: a feasibility study.

Computer methods in biomechanics and biomedical engineering

Campion D, Dakhil N, Llari M, Evin M, Mo F, Thefenne L, Behr M.
PMID: 29088638
Comput Methods Biomech Biomed Engin. 2017 Oct;20:35-36. doi: 10.1080/10255842.2017.1382848.

No abstract available.

Human motor control of landing from a drop in simulated microgravity.

Journal of applied physiology (Bethesda, Md. : 1985)

Gambelli CN, Theisen D, Willems PA, Schepens B.
PMID: 27516535
J Appl Physiol (1985). 2016 Sep 01;121(3):760-770. doi: 10.1152/japplphysiol.00305.2016. Epub 2016 Aug 11.

Landing on the ground on one's feet implies that the energy gained during the fall be dissipated. The aim of this study is to assess human motor control of landing in different conditions of fall initiation, simulated gravity, and...

Longitudinal evaluation of criteria for subjective cognitive decline and preclinical Alzheimer's disease in a memory clinic sample.

Alzheimer's & dementia (Amsterdam, Netherlands)

Eckerström M, Göthlin M, Rolstad S, Hessen E, Eckerström C, Nordlund A, Johansson B, Svensson J, Jonsson M, Sacuiu S, Wallin A.
PMID: 28560310
Alzheimers Dement (Amst). 2017 May 16;8:96-107. doi: 10.1016/j.dadm.2017.04.006. eCollection 2017.

INTRODUCTION: Subjective cognitive decline (SCD) and biomarker-based "at-risk" concepts such as "preclinical" Alzheimer's disease (AD) have been developed to predict AD dementia before objective cognitive impairment is detectable. We longitudinally evaluated cognitive outcome when using these classifications.METHODS: Memory clinic...

Trans people are being let down by the Health Service.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

Benestad EEP, Thesen J, Aars H, Olsen GF, Bjørkman M.
PMID: 29135196
Tidsskr Nor Laegeforen. 2017 Nov 13;137(21). doi: 10.4045/tidsskr.17.0422. Print 2017 Nov 14.

No abstract available.

No survival improvement in patients with high-risk multiple myeloma harbouring del(17p) and/or t(4;14) over the two past decades.

British journal of haematology

Chalopin T, Vallet N, Theisen O, Ochmann M, Tiab M, Godmer P, Barin C, Hérault O, Gyan E, Le Gouill S, Avet-Loiseau H, Benboubker L, Moreau P, Touzeau C.
PMID: 33928635
Br J Haematol. 2021 Aug;194(3):635-638. doi: 10.1111/bjh.17488. Epub 2021 Apr 29.

No abstract available.

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.

Oncogene

Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL.
PMID: 34145397
Oncogene. 2021 Jul;40(29):4759-4769. doi: 10.1038/s41388-021-01876-5. Epub 2021 Jun 18.

Ewing sarcoma is an aggressive bone cancer of children and young adults defined by the presence of a chromosomal translocation: t(11;22)(q24;q12). The encoded protein, EWS/FLI, fuses the amino-terminal domain of EWS to the carboxyl-terminus of FLI. The EWS portion...

Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein.

Epigenetics

Theisen ER, Selich-Anderson J, Miller KR, Tanner JM, Taslim C, Pishas KI, Sharma S, Lessnick SL.
PMID: 32842875
Epigenetics. 2021 Apr;16(4):405-424. doi: 10.1080/15592294.2020.1805678. Epub 2020 Aug 25.

Paediatric cancers commonly harbour quiet mutational landscapes and are instead characterized by single driver events such as the mutation of critical chromatin regulators, expression of oncohistones, or expression of oncogenic fusion proteins. These events ultimately promote malignancy through disruption...

Discrimination of deletion to point cytokine mutants based on an array of cross-reactive receptors mimicking protein recognition by heparan sulfate.

Analytical and bioanalytical chemistry

Genua M, Garçon LA, Sergeeva YN, Saesen E, Musnier B, Buhot A, Billon M, Gout E, Sadir R, Lortat-Jacob H, Le Narvor C, Bonnaffé D, Livache T, Hou Y.
PMID: 34258651
Anal Bioanal Chem. 2022 Jan;414(1):551-559. doi: 10.1007/s00216-021-03516-z. Epub 2021 Jul 13.

Differential sensing of proteins based on cross-reactive arrays and pattern recognition is a promising technique for the detection and identification of proteins. In this study, a rational biomimetic strategy has been used to prepare sensing materials capable of discriminating...

Showing 181 to 192 of 196 entries