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Showing 3901 to 3910 of 3910 entries
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Potentiation of Muscarinic M.

The Journal of pharmacology and experimental therapeutics

Okimoto R, Ino K, Ishizu K, Takamatsu H, Sakamoto K, Yuyama H, Fuji H, Someya A, Ohtake A, Ishigami T, Masuda N, Takeda M, Kajioka S, Yoshimura N.
PMID: 34244231
J Pharmacol Exp Ther. 2021 Oct;379(1):64-73. doi: 10.1124/jpet.121.000709. Epub 2021 Jul 08.

Muscarinic M

Drainage Retinotomy Confers Risk of Epiretinal Membrane Formation After Vitrectomy for Rhegmatogenous Retinal Detachment Repair.

American journal of ophthalmology

Ishikawa K, Akiyama M, Mori K, Nakama T, Notomi S, Nakao S, Kohno RI, Takeda A, Sonoda KH.
PMID: 34339662
Am J Ophthalmol. 2021 Jul 30;234:20-27. doi: 10.1016/j.ajo.2021.07.028. Epub 2021 Jul 30.

PURPOSE: To describe the factors associated with epiretinal membrane (ERM) formation in eyes treated with pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).DESIGN: Nationwide, multicenter, clinical cohort study based on registry data.METHODS: We reviewed 2239 cases treated with...

Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels.

Science advances

Kurth I, Yamaguchi N, Andreu-Agullo C, Tian HS, Sridhar S, Takeda S, Gonsalves FC, Loo JM, Barlas A, Manova-Todorova K, Busby R, Bendell JC, Strauss J, Fakih M, McRee AJ, Hendifar AE, Rosen LS, Cercek A, Wasserman R, Szarek M, Spector SL, Raza S, Tavazoie MF, Tavazoie SF.
PMID: 34613776
Sci Adv. 2021 Oct 08;7(41):eabi7511. doi: 10.1126/sciadv.abi7511. Epub 2021 Oct 06.

[Figure: see text].

Preparation of Oxysterols by C-H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst.

Molecules (Basel, Switzerland)

Fujii Y, Yoritate M, Makino K, Igawa K, Takeda D, Doiuchi D, Tomooka K, Uchida T, Hirai G.
PMID: 35011456
Molecules. 2021 Dec 30;27(1). doi: 10.3390/molecules27010225.

Seven mono- and dihydroxycholesterols were prepared by direct C-H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh

Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning.

Scientific reports

Ito S, Mine Y, Yoshimi Y, Takeda S, Tanaka A, Onishi A, Peng TY, Nakamoto T, Nagasaki T, Kakimoto N, Murayama T, Tanimoto K.
PMID: 34997167
Sci Rep. 2022 Jan 07;12(1):221. doi: 10.1038/s41598-021-04354-w.

Temporomandibular disorders are typically accompanied by a number of clinical manifestations that involve pain and dysfunction of the masticatory muscles and temporomandibular joint. The most important subgroup of articular abnormalities in patients with temporomandibular disorders includes patients with different...

Fasting Plasma Glucose and Incident Colorectal Cancer: Analysis of a Nationwide Epidemiological Database.

The Journal of clinical endocrinology and metabolism

Itoh H, Kaneko H, Okada A, Yano Y, Morita K, Seki H, Kiriyama H, Kamon T, Fujiu K, Matsuoka S, Nakamura S, Michihata N, Jo T, Takeda N, Morita H, Nishiyama A, Node K, Yasunaga H, Komuro I.
PMID: 34378781
J Clin Endocrinol Metab. 2021 Jun 25; doi: 10.1210/clinem/dgab466. Epub 2021 Jun 25.

CONTEXT: Although diabetes mellitus (DM) was reported to be associated with incident colorectal cancer (CRC), the detailed association between fasting plasma glucose (FPG) and incident CRC has not been fully understood.OBJECTIVE: We assessed whether hyperglycemia is associated with a...

Associations between depressive symptoms and geriatric syndromes in community-dwelling older adults in Japan: A cross-sectional study.

Preventive medicine reports

Imaoka M, Nakao H, Nakamura M, Tazaki F, Hida M, Omizu T, Imai R, Takeda M.
PMID: 33767949
Prev Med Rep. 2021 Mar 10;22:101353. doi: 10.1016/j.pmedr.2021.101353. eCollection 2021 Jun.

It is estimated that 7.2% of community-dwelling older adults worldwide have major depression. Therefore, this study aimed to investigate the relationship between geriatric syndromes and depressive symptoms. Data were obtained from the Kaizuka Dementia Prevention Study 2018 and 2019,...

Amorphous cellulose nanofiber supercapacitors.

Scientific reports

Fukuhara M, Kuroda T, Hasegawa F, Hashida T, Takeda M, Fujima N, Morita M, Nakatani T.
PMID: 33742038
Sci Rep. 2021 Mar 19;11(1):6436. doi: 10.1038/s41598-021-85901-3.

Despite the intense interest in cellulose nanofibers (CNFs) for biomedical and engineering applications, no research findings about the electrical energy storage of CNF have been reported yet. Here, we present the first electroadsorption effects of an amorphous cellulose nanofiber...

Successful treatment of a case of hormone receptor-positive metastatic extramammary Paget disease with tamoxifen.

Investigational new drugs

Isomoto K, Haratani K, Watanabe S, Takeda M, Iwasa T, Nakagawa K.
PMID: 34463889
Invest New Drugs. 2022 Feb;40(1):194-197. doi: 10.1007/s10637-021-01168-5. Epub 2021 Aug 31.

Extramammary Paget disease (EMPD) is a rare cutaneous adenocarcinoma that usually is of epidermal origin and shows glandular differentiation and that is treated by wide local excision depending on the disease extent. For widely metastatic disease, however, a standard...

Direct platelet adhesion potentiates group 2 innate lymphoid cell functions.

Allergy

Orimo K, Tamari M, Takeda T, Kubo T, Rückert B, Motomura K, Sugiyama H, Yamada A, Saito K, Arae K, Kuriyama M, Hara M, Soyka MB, Ikutani M, Yamaguchi S, Morimoto N, Nakabayashi K, Hata K, Matsuda A, Akdis CA, Sudo K, Saito H, Nakae S, Tamaoki J, Tagaya E, Matsumoto K, Morita H.
PMID: 34402091
Allergy. 2021 Aug 17; doi: 10.1111/all.15057. Epub 2021 Aug 17.

BACKGROUND: Platelets are thought to be involved in the pathophysiology of asthma, presumably through direct adhesion to inflammatory cells, including group 2 innate lymphoid cells (ILC2s). Here, we tried to elucidate the effects of platelet adhesion to ILC2s in...

Showing 3901 to 3910 of 3910 entries