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Showing 2617 to 2628 of 2647 entries
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Is Neoadjuvant Treatment Justified in Clinical T1 Pancreatic Ductal Adenocarcinoma?.

Journal of clinical medicine

Kim HS, Nakagawa K, Akahori T, Nakamura K, Takagi T, Sho M, Park JS, Yoon DS.
PMID: 33672686
J Clin Med. 2021 Feb 20;10(4). doi: 10.3390/jcm10040873.

No abstract available.

A novel COL4A1 variant associated with recurrent epistaxis and glioblastoma.

Human genome variation

Muto K, Miyamoto R, Terasawa Y, Shimatani Y, Hara K, Kakimoto T, Fukumoto T, Osaki Y, Fujita K, Harada M, Uehara H, Takagi Y, Izumi Y.
PMID: 33990551
Hum Genome Var. 2021 May 14;8(1):18. doi: 10.1038/s41439-021-00150-0.

COL4A1-related disorders are characterized by a higher incidence of cerebral hemorrhage than other hereditary cerebral small vessel diseases. Accumulating data have shown broad phenotypic variations, and extracerebral hemorrhages have been linked to these disorders. Moreover, the coexistence of neural...

Isoforms of IDH in breast carcinoma: IDH2 as a potent prognostic factor associated with proliferation in estrogen-receptor positive cases.

Breast cancer (Tokyo, Japan)

Minemura H, Takagi K, Sato A, Yamaguchi M, Hayashi C, Miki Y, Harada-Shoji N, Miyashita M, Sasano H, Suzuki T.
PMID: 33713004
Breast Cancer. 2021 Jul;28(4):915-926. doi: 10.1007/s12282-021-01228-x. Epub 2021 Mar 12.

BACKGROUND: Isocitrate dehydrogenase (IDH) is an important enzyme that oxidatively decarboxylates isocitrate to α-ketoglutarate, and three isoforms (IDH1-3) have been identified. Overexpression and/or downregulation of IDH isoforms was reported in several human malignancies, suggesting importance of IDH in oncogenesis....

PAX3/7-FOXO1 fusion-negative alveolar rhabdomyosarcoma in Schuurs-Hoeijmakers syndrome.

Journal of human genetics

Ohkawa T, Nishimura A, Kosaki K, Aoki-Nogami Y, Tomizawa D, Kashimada K, Morio T, Kato M, Mizutani S, Takagi M.
PMID: 34341476
J Hum Genet. 2021 Aug 02; doi: 10.1038/s10038-021-00965-3. Epub 2021 Aug 02.

PAX3/7-FOXO1 fusion-negative alveolar rhabdomyosarcoma (ARMS) developed in a patient presenting with intellectual disability and dysmorphic facial features. Whole exome sequencing analysis of a germline sample identified a PACS1 c.607 C>T de novo variant and the patient was diagnosed with...

Technique of vessel-skeletonized parenchyma-sparing hepatectomy for the oncological treatment of bilobar colorectal liver metastases.

Langenbeck's archives of surgery

Umeda Y, Nagasaka T, Takagi K, Yoshida R, Yoshida K, Fuji T, Matsuda T, Yasui K, Kumano K, Sato H, Yagi T, Fujiwara T.
PMID: 34839388
Langenbecks Arch Surg. 2021 Nov 27; doi: 10.1007/s00423-021-02373-9. Epub 2021 Nov 27.

BACKGROUND: To aid in the oncological management of multiple bilobar colorectal liver metastases (CRLMs), we describe a new surgical procedure, VEssel-Skeletonized PArenchyma-sparing Hepatectomy (VESPAH).STUDY DESIGN: Of 152 patients with CRLMs treated with hepatectomy, 33 patients had multiple bilobar liver...

Safety and feasibility of same-day discharge in patients receiving pulmonary vein isolation-systematic review and a meta-analysis.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Sahashi Y, Kawamura I, Aikawa T, Takagi H, Briasoulis A, Kuno T.
PMID: 33630213
J Interv Card Electrophysiol. 2021 Feb 25; doi: 10.1007/s10840-021-00967-3. Epub 2021 Feb 25.

PURPOSE: The purpose of this systematic review and meta-analysis was to evaluate the feasibility and safety of a same-day discharge protocol following pulmonary vein isolation (PVI).METHODS: PubMed and Embase were systematically investigated from the inception to 20 July 2020....

Contribution of on-road transportation to PM.

Scientific reports

Li C, Managi S.
PMID: 34716375
Sci Rep. 2021 Oct 29;11(1):21320. doi: 10.1038/s41598-021-00862-x.

Fine particulate matter (PM

Validation of the SCAT5 and Child SCAT5 Word-List Memory Task.

Journal of neurotrauma

Shapiro JS, Hearps S, Rausa VC, Anderson V, Anderson N, Pugh R, Chau T, Clarke C, Davis GA, Fabiano F, Fan F, Parkin GM, Takagi M, Babl FE.
PMID: 33765839
J Neurotrauma. 2021 May 10; doi: 10.1089/neu.2020.7414. Epub 2021 May 10.

The Sports Concussion Assessment Tool-5th Edition (SCAT5) and the child version (Child SCAT5) are the current editions of the SCAT and have updated the memory testing component from previous editions. This study aimed to validate this new memory component...

Assessment of appropriate body mass index cut-off points for long-term mortality among ST-elevation myocardial infarction survivors in Asian population using machine learning algorithm.

Heart and vessels

Yoshioka N, Takagi K, Tanaka A, Morita Y, Yoshida R, Nagai H, Kanzaki Y, Watanabe N, Yamauchi R, Komeyama S, Sugiyama H, Shimojo K, Imaoka T, Sakamoto G, Ohi T, Goto H, Ishii H, Morishima I, Murohara T.
PMID: 34365566
Heart Vessels. 2021 Aug 07; doi: 10.1007/s00380-021-01916-w. Epub 2021 Aug 07.

Low body mass index (BMI) is a predictor of adverse events in patients with ST-elevated myocardial infarction (STEMI) in Western countries. Because the average BMI of Asians is significantly lower than that of the Western population, the appropriate cut-off...

Limited impact of warm ischemic threshold for partial nephrectomy in the robotic surgery era: A propensity score matching study.

International journal of urology : official journal of the Japanese Urological Association

Ishiyama Y, Kondo T, Tachibana H, Yoshida K, Takagi T, Iizuka J, Tanabe K.
PMID: 34472136
Int J Urol. 2021 Dec;28(12):1219-1225. doi: 10.1111/iju.14674. Epub 2021 Sep 01.

OBJECTIVES: To evaluate the association between extended (≥30 min) warm ischemic time and renal function in patients undergoing robot-assisted partial nephrectomy.METHODS: This multi-institutional study retrospectively recruited 1131 patients who underwent robot-assisted partial nephrectomy. Patients were classified into shorter (

Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and bioprosthetic valves: A meta-analysis.

The Journal of thoracic and cardiovascular surgery

Yokoyama Y, Briasoulis A, Ueyama H, Mori M, Iwagami M, Misumida N, Takagi H, Kuno T.
PMID: 34417050
J Thorac Cardiovasc Surg. 2021 Jul 29; doi: 10.1016/j.jtcvs.2021.07.034. Epub 2021 Jul 29.

BACKGROUND: The optimal anticoagulation strategy for patients with bioprosthetic valves and atrial fibrillation remains uncertain. We conducted a meta-analysis using updated evidence comparing direct anticoagulants (DOACs) and vitamin K antagonists (VKAs) in patients with bioprosthetic valves and atrial fibrillation.METHODS:...

Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use.

Bone

Tsuda E, Fukuda C, Okada A, Karibe T, Hiruma Y, Takagi N, Isumi Y, Yamamoto T, Hasegawa T, Uehara S, Koide M, Udagawa N, Amizuka N, Kumakura S.
PMID: 34715394
Bone. 2021 Oct 27;155:116241. doi: 10.1016/j.bone.2021.116241. Epub 2021 Oct 27.

Recent studies have established the idea that Siglec-15 is involved in osteoclast differentiation and/or function, and it is anticipated that therapies suppressing Siglec-15 function can be used to treat bone diseases such as osteoporosis. We have produced rat monoclonal...

Showing 2617 to 2628 of 2647 entries