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Showing 109 to 110 of 110 entries
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Molecules (Basel, Switzerland)

Torok R, Horompoly K, Szigeti M, Guttman A, Vitai M, Koranyi L, Jarvas G.
PMID: 34770808
Molecules. 2021 Oct 22;26(21). doi: 10.3390/molecules26216399.

Currently, diagnosing type 2 diabetes (T2D) is a great challenge. Thus, there is a need to find rapid, simple, and reliable analytical methods that can detect the disease at an early stage. The aim of this work was to...

N-glycosylation structure - function characterization of omalizumab, an anti-asthma biotherapeutic product.

Journal of pharmaceutical and biomedical analysis

Szabo M, Filep C, Nagy M, Sarkozy D, Szigeti M, Sperling E, Csanky E, Guttman A.
PMID: 34864596
J Pharm Biomed Anal. 2021 Nov 25;209:114483. doi: 10.1016/j.jpba.2021.114483. Epub 2021 Nov 25.

Omalizumab, a glycoprotein based biotherapeutics, is one of the most frequently used targeted antibody biopharmaceutical to reduce asthma exacerbations, improve lung function and reduce oral corticosteroid use. The effector function and clearance time of such glycoprotein drugs is affected...

Showing 109 to 110 of 110 entries