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Showing 13 to 24 of 211 entries
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Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification.

Pharmaceutics

Schuster S, Biri-Kovács B, Szeder B, Buday L, Gardi J, Szabó Z, Halmos G, Mező G.
PMID: 30423956
Pharmaceutics. 2018 Nov 09;10(4). doi: 10.3390/pharmaceutics10040223.

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of...

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Schuster S, Biri-Kovács B, Szeder B, et al. Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification. Pharmaceutics. 2018;10(4)doi: 10.3390/pharmaceutics10040223.
Schuster, S., Biri-Kovács, B., Szeder, B., Buday, L., Gardi, J., Szabó, Z., Halmos, G., & Mező, G. (2018). Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification. Pharmaceutics, 10(4), . https://doi.org/10.3390/pharmaceutics10040223
Schuster, Sabine, et al. "Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification." Pharmaceutics vol. 10,4 (2018). doi: https://doi.org/10.3390/pharmaceutics10040223
Schuster S, Biri-Kovács B, Szeder B, Buday L, Gardi J, Szabó Z, Halmos G, Mező G. Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification. Pharmaceutics. 2018 Nov 09;10(4). doi: 10.3390/pharmaceutics10040223. PMID: 30423956; PMCID: PMC6320914.
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Superconformal anomalies from the path-integral measure.

Physical review. D, Particles and fields

Spence B.
PMID: 9957172
Phys Rev D Part Fields. 1986 Jul 15;34(2):533-535. doi: 10.1103/physrevd.34.533.

No abstract available.

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Spence B. Superconformal anomalies from the path-integral measure. Phys Rev D Part Fields. 1986;34(2):533-535doi: 10.1103/physrevd.34.533.
Spence, B. (1986). Superconformal anomalies from the path-integral measure. Physical review. D, Particles and fields, 34(2), 533-535. https://doi.org/10.1103/physrevd.34.533
Spence. "Superconformal anomalies from the path-integral measure." Physical review. D, Particles and fields vol. 34,2 (1986): 533-535. doi: https://doi.org/10.1103/physrevd.34.533
Spence B. Superconformal anomalies from the path-integral measure. Phys Rev D Part Fields. 1986 Jul 15;34(2):533-535. doi: 10.1103/physrevd.34.533. PMID: 9957172.
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Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals.

Journal of psychopharmacology (Oxford, England)

McCulloch DE, Madsen MK, Stenbæk DS, Kristiansen S, Ozenne B, Jensen PS, Knudsen GM, Fisher PM.
PMID: 34189985
J Psychopharmacol. 2021 Jun 30;2698811211026454. doi: 10.1177/02698811211026454. Epub 2021 Jun 30.

BACKGROUND: Psilocybin is a psychedelic drug that has shown lasting positive effects on clinical symptoms and self-reported well-being following a single dose. There has been little research into the long-term effects of psilocybin on brain connectivity in humans.AIM: Evaluate...

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McCulloch DE, Madsen MK, Stenbæk DS, et al. Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals. J Psychopharmacol. 2021;2698811211026454doi: 10.1177/02698811211026454.
McCulloch, D. E., Madsen, M. K., Stenbæk, D. S., Kristiansen, S., Ozenne, B., Jensen, P. S., Knudsen, G. M., & Fisher, P. M. (2021). Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals. Journal of psychopharmacology (Oxford, England), 2698811211026454. https://doi.org/10.1177/02698811211026454
McCulloch, Drummond E-Wen, et al. "Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals." Journal of psychopharmacology (Oxford, England) vol. (2021): 2698811211026454. doi: https://doi.org/10.1177/02698811211026454
McCulloch DE, Madsen MK, Stenbæk DS, Kristiansen S, Ozenne B, Jensen PS, Knudsen GM, Fisher PM. Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals. J Psychopharmacol. 2021 Jun 30;2698811211026454. doi: 10.1177/02698811211026454. Epub 2021 Jun 30. PMID: 34189985.
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Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37.

ACS pharmacology & translational science

Quemé-Peña M, Ricci M, Juhász T, Horváti K, Bősze S, Biri-Kovács B, Szeder B, Zsila F, Beke-Somfai T.
PMID: 33615169
ACS Pharmacol Transl Sci. 2020 Dec 03;4(1):155-167. doi: 10.1021/acsptsci.0c00155. eCollection 2021 Feb 12.

The host defense peptide LL-37 is the only human cathelicidin, characterized by pleiotropic activity ranging from immunological to anti-neoplastic functions. However, its overexpression has been associated with harmful inflammatory responses and apoptosis. Thus, for the latter cases, the development...

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Quemé-Peña M, Ricci M, Juhász T, et al. Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37. ACS Pharmacol Transl Sci. 2020;4(1):155-167doi: 10.1021/acsptsci.0c00155.
Quemé-Peña, M., Ricci, M., Juhász, T., Horváti, K., Bősze, S., Biri-Kovács, B., Szeder, B., Zsila, F., & Beke-Somfai, T. (2021). Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37. ACS pharmacology & translational science, 4(1), 155-167. https://doi.org/10.1021/acsptsci.0c00155
Quemé-Peña, Mayra, et al. "Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37." ACS pharmacology & translational science vol. 4,1 (2021): 155-167. doi: https://doi.org/10.1021/acsptsci.0c00155
Quemé-Peña M, Ricci M, Juhász T, Horváti K, Bősze S, Biri-Kovács B, Szeder B, Zsila F, Beke-Somfai T. Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37. ACS Pharmacol Transl Sci. 2020 Dec 03;4(1):155-167. doi: 10.1021/acsptsci.0c00155. eCollection 2021 Feb 12. PMID: 33615169; PMCID: PMC7887748.
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RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design.

Drugs - real world outcomes

Xia AD, Schaefer CP, Szende A, Jahn E, Hirst MJ.
PMID: 31741199
Drugs Real World Outcomes. 2019 Dec;6(4):193-203. doi: 10.1007/s40801-019-00167-6.

OBJECTIVES: Real-world evidence (RWE) is essential for the development of pharmaceutical and medical technologies and informs treatment-related decisions by regulatory agencies, payers, healthcare providers, and patients. Given that planning RWE studies present diverse challenges, we developed the RWE Framework,...

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Xia AD, Schaefer CP, Szende A, et al. RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design. Drugs Real World Outcomes. 2019;6(4):193-203doi: 10.1007/s40801-019-00167-6.
Xia, A. D., Schaefer, C. P., Szende, A., Jahn, E., & Hirst, M. J. (2019). RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design. Drugs - real world outcomes, 6(4), 193-203. https://doi.org/10.1007/s40801-019-00167-6
Xia, Andrew D, et al. "RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design." Drugs - real world outcomes vol. 6,4 (2019): 193-203. doi: https://doi.org/10.1007/s40801-019-00167-6
Xia AD, Schaefer CP, Szende A, Jahn E, Hirst MJ. RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design. Drugs Real World Outcomes. 2019 Dec;6(4):193-203. doi: 10.1007/s40801-019-00167-6. PMID: 31741199; PMCID: PMC6879703.
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Real-World Treatment Patterns and Health-Resource Utilization in Patients with Hepatocellular Carcinoma (HCC) Following Failure of Sorafenib: A Retrospective Chart Review of 127 Patients in South Korea.

Drugs - real world outcomes

Novick D, Cho JM, Colman S, Szende A.
PMID: 34905182
Drugs Real World Outcomes. 2021 Dec 14; doi: 10.1007/s40801-021-00286-z. Epub 2021 Dec 14.

BACKGROUND: European, US, Asian and Korean treatment guidelines all recommend sorafenib as first-line systemic therapy in patients with hepatocellular carcinoma (HCC). However, due to the emergence of several new treatments, post-sorafenib treatment patterns in real-world clinical practice are less...

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Novick D, Cho JM, Colman S, et al. Real-World Treatment Patterns and Health-Resource Utilization in Patients with Hepatocellular Carcinoma (HCC) Following Failure of Sorafenib: A Retrospective Chart Review of 127 Patients in South Korea. Drugs Real World Outcomes. 2021;doi: 10.1007/s40801-021-00286-z.
Novick, D., Cho, J. M., Colman, S., & Szende, A. (2021). Real-World Treatment Patterns and Health-Resource Utilization in Patients with Hepatocellular Carcinoma (HCC) Following Failure of Sorafenib: A Retrospective Chart Review of 127 Patients in South Korea. Drugs - real world outcomes, . https://doi.org/10.1007/s40801-021-00286-z
Novick, Diego, et al. "Real-World Treatment Patterns and Health-Resource Utilization in Patients with Hepatocellular Carcinoma (HCC) Following Failure of Sorafenib: A Retrospective Chart Review of 127 Patients in South Korea." Drugs - real world outcomes vol. (2021). doi: https://doi.org/10.1007/s40801-021-00286-z
Novick D, Cho JM, Colman S, Szende A. Real-World Treatment Patterns and Health-Resource Utilization in Patients with Hepatocellular Carcinoma (HCC) Following Failure of Sorafenib: A Retrospective Chart Review of 127 Patients in South Korea. Drugs Real World Outcomes. 2021 Dec 14; doi: 10.1007/s40801-021-00286-z. Epub 2021 Dec 14. PMID: 34905182.
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Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters.

NPJ vaccines

Tostanoski LH, Chandrashekar A, Patel S, Yu J, Jacob-Dolan C, Chang A, Powers OC, Sellers D, Gardner S, Barrett J, Sanborn O, Stephenson KE, Ansel JL, Jaegle K, Seaman MS, Porto M, Lok M, Spence B, Cayer K, Nase D, Holman S, Bradette H, Kar S, Andersen H, Lewis MG, Cox F, Tolboom JTBM, de Groot AM, Heerwegh D, Le Gars M, Sadoff J, Wegmann F, Zahn RC, Schuitemaker H, Barouch DH.
PMID: 35013325
NPJ Vaccines. 2022 Jan 10;7(1):2. doi: 10.1038/s41541-021-00427-z.

SARS-CoV-2 Spike-specific binding and neutralizing antibodies, elicited either by natural infection or vaccination, have emerged as potential correlates of protection. An important question, however, is whether vaccine-elicited antibodies in humans provide direct, functional protection from SARS-CoV-2 infection and disease....

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Tostanoski LH, Chandrashekar A, Patel S, et al. Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters. NPJ Vaccines. 2022;7(1):2doi: 10.1038/s41541-021-00427-z.
Tostanoski, L. H., Chandrashekar, A., Patel, S., Yu, J., Jacob-Dolan, C., Chang, A., Powers, O. C., Sellers, D., Gardner, S., Barrett, J., Sanborn, O., Stephenson, K. E., Ansel, J. L., Jaegle, K., Seaman, M. S., Porto, M., Lok, M., Spence, B., Cayer, K., Nase, D., Holman, S., Bradette, H., Kar, S., Andersen, H., Lewis, M. G., Cox, F., Tolboom, J. T. B. M., de Groot, A. M., Heerwegh, D., Le Gars, M., Sadoff, J., Wegmann, F., Zahn, R. C., Schuitemaker, H., & Barouch, D. H. (2022). Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters. NPJ vaccines, 7(1), 2. https://doi.org/10.1038/s41541-021-00427-z
Tostanoski, Lisa H, et al. "Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters." NPJ vaccines vol. 7,1 (2022): 2. doi: https://doi.org/10.1038/s41541-021-00427-z
Tostanoski LH, Chandrashekar A, Patel S, Yu J, Jacob-Dolan C, Chang A, Powers OC, Sellers D, Gardner S, Barrett J, Sanborn O, Stephenson KE, Ansel JL, Jaegle K, Seaman MS, Porto M, Lok M, Spence B, Cayer K, Nase D, Holman S, Bradette H, Kar S, Andersen H, Lewis MG, Cox F, Tolboom JTBM, de Groot AM, Heerwegh D, Le Gars M, Sadoff J, Wegmann F, Zahn RC, Schuitemaker H, Barouch DH. Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters. NPJ Vaccines. 2022 Jan 10;7(1):2. doi: 10.1038/s41541-021-00427-z. PMID: 35013325.
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Transferrin binding protein-B from .

Journal of biomolecular structure & dynamics

Karale A, Lokhande KB, Shende N, Swamy KV, Dhere R, Nawani N, Mallya A.
PMID: 34726113
J Biomol Struct Dyn. 2021 Nov 02;1-11. doi: 10.1080/07391102.2021.1994878. Epub 2021 Nov 02.

The linking of polysaccharide in glycoconjugate vaccine with carrier protein is an imperative step to develop a strong memory response. The excessive use of similar carrier protein known to result in bystander immunity warrants an urgent need for new...

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Karale A, Lokhande KB, Shende N, et al. Transferrin binding protein-B from . J Biomol Struct Dyn. 2021;1-11doi: 10.1080/07391102.2021.1994878.
Karale, A., Lokhande, K. B., Shende, N., Swamy, K. V., Dhere, R., Nawani, N., & Mallya, A. (2021). Transferrin binding protein-B from . Journal of biomolecular structure & dynamics, 1-11. https://doi.org/10.1080/07391102.2021.1994878
Karale, Abhijeet, et al. "Transferrin binding protein-B from ." Journal of biomolecular structure & dynamics vol. (2021): 1-11. doi: https://doi.org/10.1080/07391102.2021.1994878
Karale A, Lokhande KB, Shende N, Swamy KV, Dhere R, Nawani N, Mallya A. Transferrin binding protein-B from . J Biomol Struct Dyn. 2021 Nov 02;1-11. doi: 10.1080/07391102.2021.1994878. Epub 2021 Nov 02. PMID: 34726113.
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Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach.

Computational and structural biotechnology journal

Wong LM, Li WT, Shende N, Tsai JC, Ma J, Chakladar J, Gnanasekar A, Qu Y, Dereschuk K, Wang-Rodriguez J, Ongkeko WM.
PMID: 34900135
Comput Struct Biotechnol J. 2021 Nov 18;19:6240-6254. doi: 10.1016/j.csbj.2021.11.013. eCollection 2021.

BACKGROUND: The mechanisms of carcinogenesis from viral infections are extraordinarily complex and not well understood. Traditional methods of analyzing RNA-sequencing data may not be sufficient for unraveling complicated interactions between viruses and host cells. Using RNA and DNA-sequencing data...

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Wong LM, Li WT, Shende N, et al. Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach. Comput Struct Biotechnol J. 2021;19:6240-6254doi: 10.1016/j.csbj.2021.11.013.
Wong, L. M., Li, W. T., Shende, N., Tsai, J. C., Ma, J., Chakladar, J., Gnanasekar, A., Qu, Y., Dereschuk, K., Wang-Rodriguez, J., & Ongkeko, W. M. (2021). Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach. Computational and structural biotechnology journal, 196240-6254. https://doi.org/10.1016/j.csbj.2021.11.013
Wong, Lindsay M, et al. "Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach." Computational and structural biotechnology journal vol. 19 (2021): 6240-6254. doi: https://doi.org/10.1016/j.csbj.2021.11.013
Wong LM, Li WT, Shende N, Tsai JC, Ma J, Chakladar J, Gnanasekar A, Qu Y, Dereschuk K, Wang-Rodriguez J, Ongkeko WM. Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach. Comput Struct Biotechnol J. 2021 Nov 18;19:6240-6254. doi: 10.1016/j.csbj.2021.11.013. eCollection 2021. PMID: 34900135; PMCID: PMC8636736.
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Pharyngocutaneous Fistula and Horner's Syndrome following Loosening of Locking Screw of Anterior Cervical Plating: A Rare Case Report and Management.

Asian journal of neurosurgery

Jogani A, Rathod T, Marathe N, Mohanty S, Shende C.
PMID: 34211894
Asian J Neurosurg. 2021 Feb 23;16(1):196-199. doi: 10.4103/ajns.AJNS_230_19. eCollection 2021.

We hereby present a rare case of pharyngocutaneous fistula associated with locking screw loosening causing internal cricopharynx perforation and Horner's syndrome following anterior cervical plating. A 27-year-old male patient had undergone anterior cervical plating at C5-C7 level due to...

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Jogani A, Rathod T, Marathe N, et al. Pharyngocutaneous Fistula and Horner's Syndrome following Loosening of Locking Screw of Anterior Cervical Plating: A Rare Case Report and Management. Asian J Neurosurg. 2021;16(1):196-199doi: 10.4103/ajns.AJNS_230_19.
Jogani, A., Rathod, T., Marathe, N., Mohanty, S., & Shende, C. (2021). Pharyngocutaneous Fistula and Horner's Syndrome following Loosening of Locking Screw of Anterior Cervical Plating: A Rare Case Report and Management. Asian journal of neurosurgery, 16(1), 196-199. https://doi.org/10.4103/ajns.AJNS_230_19
Jogani, Abhinav, et al. "Pharyngocutaneous Fistula and Horner's Syndrome following Loosening of Locking Screw of Anterior Cervical Plating: A Rare Case Report and Management." Asian journal of neurosurgery vol. 16,1 (2021): 196-199. doi: https://doi.org/10.4103/ajns.AJNS_230_19
Jogani A, Rathod T, Marathe N, Mohanty S, Shende C. Pharyngocutaneous Fistula and Horner's Syndrome following Loosening of Locking Screw of Anterior Cervical Plating: A Rare Case Report and Management. Asian J Neurosurg. 2021 Feb 23;16(1):196-199. doi: 10.4103/ajns.AJNS_230_19. eCollection 2021. PMID: 34211894; PMCID: PMC8202369.
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Block copolymers in Alzheimer's disease therapy: A perceptive to revolutionize biomaterials.

Journal of controlled release : official journal of the Controlled Release Society

Revdekar A, Shende P.
PMID: 34763003
J Control Release. 2021 Nov 08;340:271-281. doi: 10.1016/j.jconrel.2021.11.007. Epub 2021 Nov 08.

Alzheimer's disease is a fatal illness associated with two persistent problems in treatment i. ineffective drug transportation across the bio-membranes and ii. on-site targeting. Such problems originate from the combinational factors for non-specific targets, physicochemical limitations in the delivery...

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Revdekar A, Shende P. Block copolymers in Alzheimer's disease therapy: A perceptive to revolutionize biomaterials. J Control Release. 2021;340:271-281doi: 10.1016/j.jconrel.2021.11.007.
Revdekar, A., & Shende, P. (2021). Block copolymers in Alzheimer's disease therapy: A perceptive to revolutionize biomaterials. Journal of controlled release : official journal of the Controlled Release Society, 340271-281. https://doi.org/10.1016/j.jconrel.2021.11.007
Revdekar, Amey, and Shende, Pravin. "Block copolymers in Alzheimer's disease therapy: A perceptive to revolutionize biomaterials." Journal of controlled release : official journal of the Controlled Release Society vol. 340 (2021): 271-281. doi: https://doi.org/10.1016/j.jconrel.2021.11.007
Revdekar A, Shende P. Block copolymers in Alzheimer's disease therapy: A perceptive to revolutionize biomaterials. J Control Release. 2021 Nov 08;340:271-281. doi: 10.1016/j.jconrel.2021.11.007. Epub 2021 Nov 08. PMID: 34763003.
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Role of lipopolysaccharides in potential applications of nanocarrier systems.

Current pharmaceutical design

Shende P, Gupta S.
PMID: 34818999
Curr Pharm Des. 2021 Nov 23; doi: 10.2174/1381612827666211124094302. Epub 2021 Nov 23.

BACKGROUND: Lipopolysaccharides (LPS) are considered the main molecular component in the outer membrane of gram-negative bacteria. The LPS molecule in the bacterial cell wall acts as a primary physical barrier and protects gram-negative bacteria from the surrounding environment. LPS...

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Shende P, Gupta S. Role of lipopolysaccharides in potential applications of nanocarrier systems. Curr Pharm Des. 2021;doi: 10.2174/1381612827666211124094302.
Shende, P., & Gupta, S. (2021). Role of lipopolysaccharides in potential applications of nanocarrier systems. Current pharmaceutical design, . https://doi.org/10.2174/1381612827666211124094302
Shende, Pravin, and Gupta, Shubham. "Role of lipopolysaccharides in potential applications of nanocarrier systems." Current pharmaceutical design vol. (2021). doi: https://doi.org/10.2174/1381612827666211124094302
Shende P, Gupta S. Role of lipopolysaccharides in potential applications of nanocarrier systems. Curr Pharm Des. 2021 Nov 23; doi: 10.2174/1381612827666211124094302. Epub 2021 Nov 23. PMID: 34818999.
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Showing 13 to 24 of 211 entries