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Showing 193 to 194 of 194 entries
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Induced pluripotent stem cell line ICGi036-A generated by reprogramming peripheral blood mononuclear cells from a patient with familial hypercholesterolemia caused due to compound heterozygous p.Ser177Leu/p.Cys352Arg mutations in LDLR.

Stem cell research

Zakharova IS, Shevchenko AI, Tmoyan NA, Elisaphenko EA, Zubkova ES, Sleptcov AA, Nazarenko MS, Ezhov MV, Kukharchuk VV, Parfyonova YV, Zakian SM.
PMID: 34999421
Stem Cell Res. 2022 Jan 03;59:102653. doi: 10.1016/j.scr.2022.102653. Epub 2022 Jan 03.

Familial hypercholesterolemia (FH) is a monogenic disease, leading to atherosclerosis due to a high level of low-density lipoprotein cholesterol. Most cases of the disease are based on pathological variants in the LDLR gene. Hepatocyte-like and endothelial cells derived from...

Holotoxin disassembly by protein disulfide isomerase is less efficient for Escherichia coli heat-labile enterotoxin than cholera toxin.

Scientific reports

Serrano A, Guyette JL, Heim JB, Taylor M, Cherubin P, Krengel U, Teter K, Tatulian SA.
PMID: 34997016
Sci Rep. 2022 Jan 07;12(1):34. doi: 10.1038/s41598-021-03939-9.

Cholera toxin (CT) and Escherichia coli heat-labile enterotoxin (LT) are structurally similar AB

Showing 193 to 194 of 194 entries