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A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis.

Neuro-oncology practice

Furuse M, Nonoguchi N, Kuroiwa T, Miyamoto S, Arakawa Y, Shinoda J, Miwa K, Iuchi T, Tsuboi K, Houkin K, Terasaka S, Tabei Y, Nakamura H, Nagane M, Sugiyama K, Terasaki M, Abe T, Narita Y, Saito N, Mukasa A, Ogasawara K, Beppu T, Kumabe T, Nariai T, Tsuyuguchi N, Nakatani E, Kurisu S, Nakagawa Y, Miyatake SI.
PMID: 27833757
Neurooncol Pract. 2016 Dec;3(4):272-280. doi: 10.1093/nop/npv064. Epub 2016 Jan 07.

BACKGROUND: Brain radiation necrosis (BRN) can be a complication of radiotherapy for primary and secondary brain tumors, as well as head and neck tumors. Since vascular endothelial growth factor (VEGF) is also a vascular permeability factor in the brain,...

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Furuse M, Nonoguchi N, Kuroiwa T, et al. A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis. Neurooncol Pract. 2016;3(4):272-280doi: 10.1093/nop/npv064.
Furuse, M., Nonoguchi, N., Kuroiwa, T., Miyamoto, S., Arakawa, Y., Shinoda, J., Miwa, K., Iuchi, T., Tsuboi, K., Houkin, K., Terasaka, S., Tabei, Y., Nakamura, H., Nagane, M., Sugiyama, K., Terasaki, M., Abe, T., Narita, Y., Saito, N., Mukasa, A., Ogasawara, K., Beppu, T., Kumabe, T., Nariai, T., Tsuyuguchi, N., Nakatani, E., Kurisu, S., Nakagawa, Y., & Miyatake, S. I. (2016). A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis. Neuro-oncology practice, 3(4), 272-280. https://doi.org/10.1093/nop/npv064
Furuse, Motomasa, et al. "A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis." Neuro-oncology practice vol. 3,4 (2016): 272-280. doi: https://doi.org/10.1093/nop/npv064
Furuse M, Nonoguchi N, Kuroiwa T, Miyamoto S, Arakawa Y, Shinoda J, Miwa K, Iuchi T, Tsuboi K, Houkin K, Terasaka S, Tabei Y, Nakamura H, Nagane M, Sugiyama K, Terasaki M, Abe T, Narita Y, Saito N, Mukasa A, Ogasawara K, Beppu T, Kumabe T, Nariai T, Tsuyuguchi N, Nakatani E, Kurisu S, Nakagawa Y, Miyatake SI. A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis. Neurooncol Pract. 2016 Dec;3(4):272-280. doi: 10.1093/nop/npv064. Epub 2016 Jan 07. PMID: 27833757; PMCID: PMC5099992.
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Direct Estimation of the Derivative of Quadratic Mutual Information with Application in Supervised Dimension Reduction.

Neural computation

Tangkaratt V, Sasaki H, Sugiyama M.
PMID: 28599116
Neural Comput. 2017 Aug;29(8):2076-2122. doi: 10.1162/NECO_a_00986. Epub 2017 Jun 09.

A typical goal of linear-supervised dimension reduction is to find a low-dimensional subspace of the input space such that the projected input variables preserve maximal information about the output variables. The dependence-maximization approach solves the supervised dimension-reduction problem through...

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Tangkaratt V, Sasaki H, Sugiyama M. Direct Estimation of the Derivative of Quadratic Mutual Information with Application in Supervised Dimension Reduction. Neural Comput. 2017;29(8):2076-2122doi: 10.1162/NECO_a_00986.
Tangkaratt, V., Sasaki, H., & Sugiyama, M. (2017). Direct Estimation of the Derivative of Quadratic Mutual Information with Application in Supervised Dimension Reduction. Neural computation, 29(8), 2076-2122. https://doi.org/10.1162/NECO_a_00986
Tangkaratt, Voot, et al. "Direct Estimation of the Derivative of Quadratic Mutual Information with Application in Supervised Dimension Reduction." Neural computation vol. 29,8 (2017): 2076-2122. doi: https://doi.org/10.1162/NECO_a_00986
Tangkaratt V, Sasaki H, Sugiyama M. Direct Estimation of the Derivative of Quadratic Mutual Information with Application in Supervised Dimension Reduction. Neural Comput. 2017 Aug;29(8):2076-2122. doi: 10.1162/NECO_a_00986. Epub 2017 Jun 09. PMID: 28599116.
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Mapping of dendritic lesions in patients with herpes simplex keratitis using in vivo confocal microscopy.

Clinical ophthalmology (Auckland, N.Z.)

Yokogawa H, Kobayashi A, Mori N, Sugiyama K.
PMID: 26445524
Clin Ophthalmol. 2015 Sep 24;9:1771-7. doi: 10.2147/OPTH.S92517. eCollection 2015.

PURPOSE: To produce a two-dimensional reconstruction map of dendritic lesions in patients with herpes simplex keratitis (HSK) using in vivo confocal microscopy.METHODS: Four eyes of four patients (mean 65.8 years) with HSK presenting with a dendritic lesion were enrolled....

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Yokogawa H, Kobayashi A, Mori N, et al. Mapping of dendritic lesions in patients with herpes simplex keratitis using in vivo confocal microscopy. Clin Ophthalmol. 2015;9:1771-7doi: 10.2147/OPTH.S92517.
Yokogawa, H., Kobayashi, A., Mori, N., & Sugiyama, K. (2015). Mapping of dendritic lesions in patients with herpes simplex keratitis using in vivo confocal microscopy. Clinical ophthalmology (Auckland, N.Z.), 91771-7. https://doi.org/10.2147/OPTH.S92517
Yokogawa, Hideaki, et al. "Mapping of dendritic lesions in patients with herpes simplex keratitis using in vivo confocal microscopy." Clinical ophthalmology (Auckland, N.Z.) vol. 9 (2015): 1771-7. doi: https://doi.org/10.2147/OPTH.S92517
Yokogawa H, Kobayashi A, Mori N, Sugiyama K. Mapping of dendritic lesions in patients with herpes simplex keratitis using in vivo confocal microscopy. Clin Ophthalmol. 2015 Sep 24;9:1771-7. doi: 10.2147/OPTH.S92517. eCollection 2015. PMID: 26445524; PMCID: PMC4590674.
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Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage.

Acute medicine & surgery

Kashiura M, Fujita H, Sugiyama K, Akashi A, Hamabe Y.
PMID: 29123765
Acute Med Surg. 2015 Jun 30;3(2):132-134. doi: 10.1002/ams2.123. eCollection 2016 Apr.

CASE: An 82-year-old man taking dabigatran was admitted with syncope. Computed tomography showed extravasation from the stomach. Laboratory data revealed renal insufficiency and prolonged activated partial thromboplastin time. The gastric endoscopy showed a gastric ulcer with an exposed vessel....

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Kashiura M, Fujita H, Sugiyama K, et al. Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage. Acute Med Surg. 2015;3(2):132-134doi: 10.1002/ams2.123.
Kashiura, M., Fujita, H., Sugiyama, K., Akashi, A., & Hamabe, Y. (2016). Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage. Acute medicine & surgery, 3(2), 132-134. https://doi.org/10.1002/ams2.123
Kashiura, Masahiro, et al. "Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage." Acute medicine & surgery vol. 3,2 (2016): 132-134. doi: https://doi.org/10.1002/ams2.123
Kashiura M, Fujita H, Sugiyama K, Akashi A, Hamabe Y. Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage. Acute Med Surg. 2015 Jun 30;3(2):132-134. doi: 10.1002/ams2.123. eCollection 2016 Apr. PMID: 29123765; PMCID: PMC5667362.
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Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty.

Allergology international : official journal of the Japanese Society of Allergology

Ishii S, Iikura M, Hojo M, Sugiyama H.
PMID: 28110895
Allergol Int. 2017 Jul;66(3):501-503. doi: 10.1016/j.alit.2016.12.008. Epub 2017 Jan 16.

No abstract available.

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Ishii S, Iikura M, Hojo M, et al. Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty. Allergol Int. 2017;66(3):501-503doi: 10.1016/j.alit.2016.12.008.
Ishii, S., Iikura, M., Hojo, M., & Sugiyama, H. (2017). Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty. Allergology international : official journal of the Japanese Society of Allergology, 66(3), 501-503. https://doi.org/10.1016/j.alit.2016.12.008
Ishii, Satoru, et al. "Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty." Allergology international : official journal of the Japanese Society of Allergology vol. 66,3 (2017): 501-503. doi: https://doi.org/10.1016/j.alit.2016.12.008
Ishii S, Iikura M, Hojo M, Sugiyama H. Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty. Allergol Int. 2017 Jul;66(3):501-503. doi: 10.1016/j.alit.2016.12.008. Epub 2017 Jan 16. PMID: 28110895.
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Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway.

OncoTargets and therapy

Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.
PMID: 24273411
Onco Targets Ther. 2013 Nov 18;6:1685-93. doi: 10.2147/OTT.S50065. eCollection 2013.

BACKGROUND: The Wnt pathway plays an important role in Hepatocarcinogenesis. We analyzed the association of the Wnt pathway with the proliferation of hepatoma cells using Wnt3a and niclosamide, a drug used to treat tapeworm infection.METHODS: We performed an MTS...

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Tomizawa M, Shinozaki F, Motoyoshi Y, et al. Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway. Onco Targets Ther. 2013;6:1685-93doi: 10.2147/OTT.S50065.
Tomizawa, M., Shinozaki, F., Motoyoshi, Y., Sugiyama, T., Yamamoto, S., Sueishi, M., & Yoshida, T. (2013). Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway. OncoTargets and therapy, 61685-93. https://doi.org/10.2147/OTT.S50065
Tomizawa, Minoru, et al. "Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway." OncoTargets and therapy vol. 6 (2013): 1685-93. doi: https://doi.org/10.2147/OTT.S50065
Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T. Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway. Onco Targets Ther. 2013 Nov 18;6:1685-93. doi: 10.2147/OTT.S50065. eCollection 2013. PMID: 24273411; PMCID: PMC3836661.
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Magnetic structure of the metallic triangular antiferromagnet Ag2NiO2.

Journal of physics. Condensed matter : an Institute of Physics journal

Nozaki H, Månsson M, Roessli B, Pomjakushin V, Kamazawa K, Ikedo Y, Fischer HE, Hansen TC, Yoshida H, Hiroi Z, Sugiyama J.
PMID: 23793164
J Phys Condens Matter. 2013 Jul 17;25(28):286005. doi: 10.1088/0953-8984/25/28/286005. Epub 2013 Jun 21.

The magnetic structure of the metallic antiferromagnet Ag2NiO2 with the Néel temperature TN = 56 K has been investigated by means of a neutron diffraction technique using a powder sample in the temperature range between 5 and 65 K....

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Nozaki H, Månsson M, Roessli B, et al. Magnetic structure of the metallic triangular antiferromagnet Ag2NiO2. J Phys Condens Matter. 2013;25(28):286005doi: 10.1088/0953-8984/25/28/286005.
Nozaki, H., Månsson, M., Roessli, B., Pomjakushin, V., Kamazawa, K., Ikedo, Y., Fischer, H. E., Hansen, T. C., Yoshida, H., Hiroi, Z., & Sugiyama, J. (2013). Magnetic structure of the metallic triangular antiferromagnet Ag2NiO2. Journal of physics. Condensed matter : an Institute of Physics journal, 25(28), 286005. https://doi.org/10.1088/0953-8984/25/28/286005
Nozaki, Hiroshi, et al. "Magnetic structure of the metallic triangular antiferromagnet Ag2NiO2." Journal of physics. Condensed matter : an Institute of Physics journal vol. 25,28 (2013): 286005. doi: https://doi.org/10.1088/0953-8984/25/28/286005
Nozaki H, Månsson M, Roessli B, Pomjakushin V, Kamazawa K, Ikedo Y, Fischer HE, Hansen TC, Yoshida H, Hiroi Z, Sugiyama J. Magnetic structure of the metallic triangular antiferromagnet Ag2NiO2. J Phys Condens Matter. 2013 Jul 17;25(28):286005. doi: 10.1088/0953-8984/25/28/286005. Epub 2013 Jun 21. PMID: 23793164.
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Corrigendum: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression.

Scientific reports

Tasaka-Fujita M, Sugiyama N, Kang W, Masaki T, Murayama A, Yamada N, Sugiyama R, Tsukuda S, Watashi K, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T.
PMID: 26670698
Sci Rep. 2015 Dec 16;5:17208. doi: 10.1038/srep17208.

No abstract available.

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Tasaka-Fujita M, Sugiyama N, Kang W, et al. Corrigendum: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression. Sci Rep. 2015;5:17208doi: 10.1038/srep17208.
Tasaka-Fujita, M., Sugiyama, N., Kang, W., Masaki, T., Murayama, A., Yamada, N., Sugiyama, R., Tsukuda, S., Watashi, K., Asahina, Y., Sakamoto, N., Wakita, T., Shin, E. C., & Kato, T. (2015). Corrigendum: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression. Scientific reports, 517208. https://doi.org/10.1038/srep17208
Tasaka-Fujita, Megumi, et al. "Corrigendum: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression." Scientific reports vol. 5 (2015): 17208. doi: https://doi.org/10.1038/srep17208
Tasaka-Fujita M, Sugiyama N, Kang W, Masaki T, Murayama A, Yamada N, Sugiyama R, Tsukuda S, Watashi K, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T. Corrigendum: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression. Sci Rep. 2015 Dec 16;5:17208. doi: 10.1038/srep17208. PMID: 26670698; PMCID: PMC4681186.
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Yb:YAG thin-disk chirped pulse amplification laser system for intense terahertz pulse generation.

Optics express

Ochi Y, Nagashima K, Maruyama M, Tsubouchi M, Yoshida F, Kohno N, Mori M, Sugiyama A.
PMID: 26072862
Opt Express. 2015 Jun 01;23(11):15057-64. doi: 10.1364/OE.23.015057.

We have developed a 1 kHz repetition picosecond laser system dedicated for intense terahertz (THz) pulse generation. The system comprises a chirped pulse amplification laser equipped with a Yb:YAG thin-disk amplifier. At room temperature, the Yb:YAG thin-disk regenerative amplifier...

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Ochi Y, Nagashima K, Maruyama M, et al. Yb:YAG thin-disk chirped pulse amplification laser system for intense terahertz pulse generation. Opt Express. 2015;23(11):15057-64doi: 10.1364/OE.23.015057.
Ochi, Y., Nagashima, K., Maruyama, M., Tsubouchi, M., Yoshida, F., Kohno, N., Mori, M., & Sugiyama, A. (2015). Yb:YAG thin-disk chirped pulse amplification laser system for intense terahertz pulse generation. Optics express, 23(11), 15057-64. https://doi.org/10.1364/OE.23.015057
Ochi, Yoshihiro, et al. "Yb:YAG thin-disk chirped pulse amplification laser system for intense terahertz pulse generation." Optics express vol. 23,11 (2015): 15057-64. doi: https://doi.org/10.1364/OE.23.015057
Ochi Y, Nagashima K, Maruyama M, Tsubouchi M, Yoshida F, Kohno N, Mori M, Sugiyama A. Yb:YAG thin-disk chirped pulse amplification laser system for intense terahertz pulse generation. Opt Express. 2015 Jun 01;23(11):15057-64. doi: 10.1364/OE.23.015057. PMID: 26072862.
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Modification of commercial NaY zeolite to give high water diffusivity and adsorb a large amount of water.

Journal of colloid and interface science

Katoh M, Kimura M, Sugino M, Horikawa T, Nakagawa K, Sugiyama S.
PMID: 26072446
J Colloid Interface Sci. 2015 Oct 01;455:220-5. doi: 10.1016/j.jcis.2015.05.050. Epub 2015 Jun 03.

By using NaY zeolites as desiccant materials, commercial NaY zeolite was alkali treated with 1 M NaOH aqueous solution and then Mg(2+) ion-exchanged by 0.5 M Mg(NO3)2 aqueous solution. Alkali treatment (AT) of NaY zeolite removed silicon atoms selectivity...

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Katoh M, Kimura M, Sugino M, et al. Modification of commercial NaY zeolite to give high water diffusivity and adsorb a large amount of water. J Colloid Interface Sci. 2015;455:220-5doi: 10.1016/j.jcis.2015.05.050.
Katoh, M., Kimura, M., Sugino, M., Horikawa, T., Nakagawa, K., & Sugiyama, S. (2015). Modification of commercial NaY zeolite to give high water diffusivity and adsorb a large amount of water. Journal of colloid and interface science, 455220-5. https://doi.org/10.1016/j.jcis.2015.05.050
Katoh, Masahiro, et al. "Modification of commercial NaY zeolite to give high water diffusivity and adsorb a large amount of water." Journal of colloid and interface science vol. 455 (2015): 220-5. doi: https://doi.org/10.1016/j.jcis.2015.05.050
Katoh M, Kimura M, Sugino M, Horikawa T, Nakagawa K, Sugiyama S. Modification of commercial NaY zeolite to give high water diffusivity and adsorb a large amount of water. J Colloid Interface Sci. 2015 Oct 01;455:220-5. doi: 10.1016/j.jcis.2015.05.050. Epub 2015 Jun 03. PMID: 26072446.
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Antimicrobial peptide LL-37 attenuates infection of hepatitis C virus.

Hepatology research : the official journal of the Japan Society of Hepatology

Matsumura T, Sugiyama N, Murayama A, Yamada N, Shiina M, Asabe S, Wakita T, Imawari M, Kato T.
PMID: 26606891
Hepatol Res. 2016 Aug;46(9):924-32. doi: 10.1111/hepr.12627. Epub 2016 Feb 04.

AIM: Although recent studies indicate that supplementation with vitamin D (VD) potentiates a sustained viral response by interferon-based therapy to chronic hepatitis C, detailed mechanisms are not fully defined. The production of cathelicidin, an antimicrobial peptide, has been demonstrated...

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Matsumura T, Sugiyama N, Murayama A, et al. Antimicrobial peptide LL-37 attenuates infection of hepatitis C virus. Hepatol Res. 2016;46(9):924-32doi: 10.1111/hepr.12627.
Matsumura, T., Sugiyama, N., Murayama, A., Yamada, N., Shiina, M., Asabe, S., Wakita, T., Imawari, M., & Kato, T. (2016). Antimicrobial peptide LL-37 attenuates infection of hepatitis C virus. Hepatology research : the official journal of the Japan Society of Hepatology, 46(9), 924-32. https://doi.org/10.1111/hepr.12627
Matsumura, Takuya, et al. "Antimicrobial peptide LL-37 attenuates infection of hepatitis C virus." Hepatology research : the official journal of the Japan Society of Hepatology vol. 46,9 (2016): 924-32. doi: https://doi.org/10.1111/hepr.12627
Matsumura T, Sugiyama N, Murayama A, Yamada N, Shiina M, Asabe S, Wakita T, Imawari M, Kato T. Antimicrobial peptide LL-37 attenuates infection of hepatitis C virus. Hepatol Res. 2016 Aug;46(9):924-32. doi: 10.1111/hepr.12627. Epub 2016 Feb 04. PMID: 26606891.
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Clinical utility of diffusion tensor imaging and fibre tractography for evaluating diffuse axonal injury with hemiparesis.

Case reports in medicine

Sugiyama K, Kondo T, Suzukamo Y, Oouchida Y, Sato M, Watanabe H, Izumi S.
PMID: 24376460
Case Rep Med. 2013;2013:321496. doi: 10.1155/2013/321496. Epub 2013 Nov 27.

Although diffuse axonal injury (DAI) frequently manifests as cognitive and/or motor disorders, abnormal brain findings are generally undetected by conventional imaging techniques. Here we report the case of a patient with DAI and hemiparesis. Although conventional MRI revealed no...

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Sugiyama K, Kondo T, Suzukamo Y, et al. Clinical utility of diffusion tensor imaging and fibre tractography for evaluating diffuse axonal injury with hemiparesis. Case Rep Med. 2013;2013:321496doi: 10.1155/2013/321496.
Sugiyama, K., Kondo, T., Suzukamo, Y., Oouchida, Y., Sato, M., Watanabe, H., & Izumi, S. (2013). Clinical utility of diffusion tensor imaging and fibre tractography for evaluating diffuse axonal injury with hemiparesis. Case reports in medicine, 2013321496. https://doi.org/10.1155/2013/321496
Sugiyama, Ken, et al. "Clinical utility of diffusion tensor imaging and fibre tractography for evaluating diffuse axonal injury with hemiparesis." Case reports in medicine vol. 2013 (2013): 321496. doi: https://doi.org/10.1155/2013/321496
Sugiyama K, Kondo T, Suzukamo Y, Oouchida Y, Sato M, Watanabe H, Izumi S. Clinical utility of diffusion tensor imaging and fibre tractography for evaluating diffuse axonal injury with hemiparesis. Case Rep Med. 2013;2013:321496. doi: 10.1155/2013/321496. Epub 2013 Nov 27. PMID: 24376460; PMCID: PMC3860099.
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