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Showing 1165 to 1175 of 1175 entries
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Treatment strategies for elderly-onset rheumatoid arthritis in the new era.

Modern rheumatology

Sugihara T.
PMID: 34791359
Mod Rheumatol. 2021 Nov 10; doi: 10.1093/mr/roab087. Epub 2021 Nov 10.

Elderly-onset rheumatoid arthritis (EORA) is characterized by acute onset and clinical features of high disease activity. Anti-cyclic citrullinated peptide antibody (ACPA) positivity or the presence of bone erosions predicts a radiological joint destruction of EORA, but ACPA-negative EORA with...

Efficacy and safety of total pancreatectomy with islet autotransplantation: A clinical study in Japan.

Journal of diabetes

Shimoda M, Chujo D, Kurokawa T, Kawabe A, Takahashi N, Ito K, Maruyama K, Shinohara K, Ajima K, Sugahara Y, Takaki T, Kajio H, Yanase M, Hinohara C, Tokuhara M, Uemura Y, Edamoto Y, Takemura N, Matsumoto S, Kokudo N.
PMID: 34324791
J Diabetes. 2021 Nov;13(11):940-942. doi: 10.1111/1753-0407.13218. Epub 2021 Aug 10.

No abstract available.

Association between high-density lipoprotein cholesterol levels and major adverse cardiovascular events in patients who underwent coronary computed tomography angiography: FU-CCTA registry.

Heart and vessels

Kawahira Y, Shiga Y, Inoue H, Suematsu Y, Tashiro K, Kato Y, Fujimi K, Takamiya Y, Kuwano T, Sugihara M, Miura SI.
PMID: 33744994
Heart Vessels. 2021 Oct;36(10):1457-1465. doi: 10.1007/s00380-021-01831-0. Epub 2021 Mar 21.

It is unclear whether higher levels of serum high-density lipoprotein cholesterol (HDL-C) prevent major adverse cardiovascular events (MACE). We prospectively evaluated 501 patients who had undergone coronary computed tomography angiography at Fukuoka University Hospital and either were clinically suspected...

The human melanoma proteome atlas-Defining the molecular pathology.

Clinical and translational medicine

Betancourt LH, Gil J, Kim Y, Doma V, Çakır U, Sanchez A, Murillo JR, Kuras M, Parada IP, Sugihara Y, Appelqvist R, Wieslander E, Welinder C, Velasquez E, de Almeida NP, Woldmar N, Marko-Varga M, Pawłowski K, Eriksson J, Szeitz B, Baldetorp B, Ingvar C, Olsson H, Lundgren L, Lindberg H, Oskolas H, Lee B, Berge E, Sjögren M, Eriksson C, Kim D, Kwon HJ, Knudsen B, Rezeli M, Hong R, Horvatovich P, Miliotis T, Nishimura T, Kato H, Steinfelder E, Oppermann M, Miller K, Florindi F, Zhou Q, Domont GB, Pizzatti L, Nogueira FCS, Horvath P, Szadai L, Tímár J, Kárpáti S, Szász AM, Malm J, Fenyö D, Ekedahl H, Németh IB, Marko-Varga G.
PMID: 34323403
Clin Transl Med. 2021 Jul;11(7):e473. doi: 10.1002/ctm2.473.

The MM500 study is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization were determined for a broad spectrum of diverse, surgically isolated...

Correction: ERdj8 governs the size of autophagosomes during the formation process.

The Journal of cell biology

Yamamoto YH, Kasai A, Omori H, Takino T, Sugihara M, Umemoto T, Hamasaki M, Hatta T, Natsume T, Morimoto RI, Arai R, Waguri S, Sato M, Sato K, Bar-Nun S, Yoshimori T, Noda T, Nagata K.
PMID: 34357389
J Cell Biol. 2020 Sep 06;220(9). doi: 10.1083/jcb.20190312707282021c. Epub 2021 Aug 06.

No abstract available.

Hypertrophic Pachymeningitis Demonstrated by Whole-Body 67Ga Scintigraphy.

Clinical nuclear medicine

Ishii S, Sugawara S, Yamakuni R, Sekino H, Ito H.
PMID: 34284475
Clin Nucl Med. 2021 Jul 20; doi: 10.1097/RLU.0000000000003833. Epub 2021 Jul 20.

ABSTRACT: Hypertrophic pachymeningitis is a rare inflammatory process characterized by thickening of the dura mater that can be idiopathic or secondary to a variety of conditions such as ANCA-related vasculitis, IgG4-related disease, Sjögren syndrome, rheumatoid arthritis, sarcoidosis, and infections....

Factors Affecting Participation in Leisure Activities in Patients after Breast Cancer Surgery.

Healthcare (Basel, Switzerland)

Akezaki Y, Nakata E, Kikuuchi M, Tominaga R, Kurokawa H, Okamoto M, Hamada M, Aogi K, Ohsumi S, Sugihara S.
PMID: 34442215
Healthcare (Basel). 2021 Aug 22;9(8). doi: 10.3390/healthcare9081078.

BACKGROUND: The purpose of this study was to investigate the factors related to patient's participation in leisure activity in breast cancer patients with axillary lymph node dissection at 3 months after surgery.METHODS: In total, 160 women who were employed...

Associations Between High Levels of High-Density Lipoprotein Cholesterol and the Presence and Severity of Coronary Artery Disease in Patients Who Have Undergone Coronary Computed Tomography Angiography.

Journal of clinical medicine research

Tashiro K, Inoue H, Shiga Y, Tsukihashi Y, Imaizumi T, Norimatsu K, Idemoto Y, Kuwano T, Sugihara M, Nishikawa H, Katsuda Y, Miura SI.
PMID: 33224375
J Clin Med Res. 2020 Nov;12(11):734-739. doi: 10.14740/jocmr4367. Epub 2020 Nov 03.

BACKGROUND: Although a recent study in a Japanese cohort indicated that extremely high-density lipoprotein cholesterol (HDL-C, ≥ 90 mg/dL) had an adverse effect on atherosclerotic cardiovascular disease mortality, we could not conclude that high levels of HDL-C were associated...

Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase.

Acta crystallographica. Section F, Structural biology communications

Murakawa T, Suzuki M, Arima T, Sugahara M, Tanaka T, Tanaka R, Iwata S, Nango E, Tono K, Hayashi H, Fukui K, Yano T, Tanizawa K, Okajima T.
PMID: 34605440
Acta Crystallogr F Struct Biol Commun. 2021 Oct 01;77:356-363. doi: 10.1107/S2053230X21008967. Epub 2021 Sep 21.

Recent advances in serial femtosecond X-ray crystallography (SFX) using X-ray free-electron lasers have paved the way for determining radiation-damage-free protein structures under nonfreezing conditions. However, the large-scale preparation of high-quality microcrystals of uniform size is a prerequisite for SFX,...

Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.

International journal of molecular sciences

Shi T, Iwama H, Fujita K, Kobara H, Nishiyama N, Fujihara S, Goda Y, Yoneyama H, Morishita A, Tani J, Yamada M, Nakahara M, Takuma K, Masaki T.
PMID: 34884875
Int J Mol Sci. 2021 Dec 02;22(23). doi: 10.3390/ijms222313071.

Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related deaths worldwide. Sorafenib has been used as a first-line systemic treatment for over a decade. However, resistance to sorafenib limits patient response and presents a major hurdle during...

Forebrain Architecture and Development in Cyclostomes, with Reference to the Early Morphology and Evolution of the Vertebrate Head.

Brain, behavior and evolution

Sugahara F, Murakami Y, Pascual-Anaya J, Kuratani S.
PMID: 34537767
Brain Behav Evol. 2021 Sep 17;1-13. doi: 10.1159/000519026. Epub 2021 Sep 17.

The vertebrate head and brain are characterized by highly complex morphological patterns. The forebrain, the most anterior division of the brain, is subdivided into the diencephalon, hypothalamus, and telencephalon from the neuromeric subdivision into prosomeres. Importantly, the telencephalon contains...

Showing 1165 to 1175 of 1175 entries