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Showing 1153 to 1164 of 1175 entries
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Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer.

International journal of clinical oncology

Tomita N, Ishida H, Tanakaya K, Yamaguchi T, Kumamoto K, Tanaka T, Hinoi T, Miyakura Y, Hasegawa H, Takayama T, Ishikawa H, Nakajima T, Chino A, Shimodaira H, Hirasawa A, Nakayama Y, Sekine S, Tamura K, Akagi K, Kawasaki Y, Kobayashi H, Arai M, Itabashi M, Hashiguchi Y, Sugihara K.
PMID: 34185173
Int J Clin Oncol. 2021 Aug;26(8):1353-1419. doi: 10.1007/s10147-021-01881-4. Epub 2021 Jun 29.

Hereditary colorectal cancer (HCRC) accounts for 

Randomized, Double-Blind, Phase III Study of Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: CONSOLE.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Hata A, Okamoto I, Inui N, Okada M, Morise M, Akiyoshi K, Takeda M, Watanabe Y, Sugawara S, Shinagawa N, Kubota K, Saeki T, Tamura T.
PMID: 34793245
J Clin Oncol. 2021 Nov 18;JCO2101315. doi: 10.1200/JCO.21.01315. Epub 2021 Nov 18.

PURPOSE: We evaluated the efficacy and safety of fosnetupitant (FosNTP) versus fosaprepitant (FosAPR) for preventing highly emetogenic chemotherapy-induced nausea and vomiting. This phase III study was the first head-to-head comparison between two different neurokinin-1 receptor antagonists in combination with...

Novel probiotic yeast from Miso promotes regulatory dendritic cell IL-10 production and attenuates DSS-induced colitis in mice.

Journal of gastroenterology

Okada Y, Tsuzuki Y, Sugihara N, Nishii S, Shibuya N, Mizoguchi A, Itoh S, Tanemoto R, Inaba K, Hanawa Y, Horiuchi K, Wada A, Higashiyama M, Watanabe C, Kurihara C, Komoto S, Tomita K, Miura S, Hokari R.
PMID: 34213612
J Gastroenterol. 2021 Sep;56(9):829-842. doi: 10.1007/s00535-021-01804-0. Epub 2021 Jul 02.

BACKGROUND: Yeasts are a type of fungi thought to have probiotic functions. In this study, we isolated a novel probiotic yeast (Zygosaccharomyces sapae strain I-6) from Miso (a traditional Japanese fermented food). We examined its effects on phenotypic changes...

The importance of genetic research on the dominant species of human intestinal indigenous microbiota.

Bioscience of microbiota, food and health

Kurihara S.
PMID: 33520565
Biosci Microbiota Food Health. 2021;40(1):19-26. doi: 10.12938/bmfh.2020-011. Epub 2020 Sep 10.

Comparisons of the changes in the gut microbiota and transcriptomes as a result of changes in diet have demonstrated that the regulation of the gene functions of intestinal bacteria is fundamental for the regulation of the intestinal environment. However,...

Successful case of direct puncture of a prosthetic bypass graft in endovascular treatment for long superficial artery chronic total occlusion: a case report.

European heart journal. Case reports

Sugihara M, Ueda Y, Yano Y, Miura SI.
PMID: 33442613
Eur Heart J Case Rep. 2020 Nov 24;4(6):1-5. doi: 10.1093/ehjcr/ytaa391. eCollection 2020 Dec.

BACKGROUND: The access site for endovascular therapy (EVT) is often limited because of multi-vascular diseases. Prior lower limb bypass can potentially limit the availability of common femoral artery access when EVT is required.CASE SUMMARY: An 88-year-old woman who presented...

Reasons for Tooth Extractions in Japan: The Second Nationwide Survey.

International dental journal

Suzuki S, Sugihara N, Kamijo H, Morita M, Kawato T, Tsuneishi M, Kobayashi K, Hasuike Y, Sato T.
PMID: 34193342
Int Dent J. 2021 Jun 28; doi: 10.1016/j.identj.2021.05.008. Epub 2021 Jun 28.

BACKGROUND: More than 10 years have passed since the first nationwide study on the reasons for tooth extraction in Japan. In the present study, we conducted the second nationwide survey to update the previous data.METHODS: This was a descriptive...

XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes.

Thyroid : official journal of the American Thyroid Association

Wang Y, Xiang YY, Sugihara J, Lu WY, Liao XH, Arvan P, Refetoff S, Liu M.
PMID: 34652970
Thyroid. 2021 Dec 31; doi: 10.1089/thy.2021.0461. Epub 2021 Dec 31.

No abstract available.

Update on diagnosis, pathophysiology, and management of diabetic kidney disease.

Nephrology (Carlton, Vic.)

Sugahara M, Pak WLW, Tanaka T, Tang SCW, Nangaku M.
PMID: 33550672
Nephrology (Carlton). 2021 Jun;26(6):491-500. doi: 10.1111/nep.13860. Epub 2021 Feb 17.

Diabetic kidney disease (DKD) is a chronic complication of diabetes mellitus which may eventually lead to end-stage kidney disease (ESKD). Despite improvements in glycaemic control and blood pressure management with renin-angiotensin-aldosterone system (RAAS) blockade, the current therapy cannot completely...

Surface-Stress Induced Embrittlement of Metals.

Nano letters

Udupa A, Sugihara T, Viswanathan K, Latanision RM, Chandrasekar S.
PMID: 34726060
Nano Lett. 2021 Nov 24;21(22):9502-9508. doi: 10.1021/acs.nanolett.1c02887. Epub 2021 Nov 02.

Environment-assisted fracture phenomena in metals are usually associated with surface energy reduction due to an adsorbed film. Here we demonstrate a unique embrittlement effect in Al that is instead mediated by surface stress, induced by an adsorbed organic monolayer....

Successful Treatment of Thrombocytopenia, Anasarca, Fever, Reticulin Myelofibrosis/Renal Insufficiency, and Organomegaly Syndrome Using Plasma Exchange Followed by Rituximab in the Intensive Care Unit.

Journal of medical cases

Otsuka Y, Shirakabe A, Asayama T, Okazaki H, Shibata Y, Shigihara S, Sawatani T, Yokose N, Asai K.
PMID: 34970369
J Med Cases. 2021 Dec;12(12):474-480. doi: 10.14740/jmc3784. Epub 2021 Dec 02.

Thrombocytopenia, anasarca, fever, reticulin myelofibrosis/renal insufficiency, and organomegaly (TAFRO) syndrome is treated using corticosteroids and/or immunosuppressive agents as first-line therapy. We report the case of a 69-year-old female with TAFRO syndrome in which the patient presented multiple organ failure...

Factors Affecting the Quality of Life of Patients with Painful Spinal Bone Metastases.

Healthcare (Basel, Switzerland)

Akezaki Y, Nakata E, Kikuuchi M, Sugihara S, Katayama Y, Katayama H, Hamada M, Ozaki T.
PMID: 34828545
Healthcare (Basel). 2021 Nov 03;9(11). doi: 10.3390/healthcare9111499.

This study examined changes in the quality of life (QOL), as well as the factors affecting QOL, among patients with painful spinal bone metastases without paralysis for 1 month after radiotherapy.METHODS: This study included 79 participants (40 male and...

Single-cell DNA and RNA sequencing of circulating tumor cells.

Scientific reports

Kojima M, Harada T, Fukazawa T, Kurihara S, Saeki I, Takahashi S, Hiyama E.
PMID: 34819539
Sci Rep. 2021 Nov 24;11(1):22864. doi: 10.1038/s41598-021-02165-7.

Single-cell sequencing of circulating tumor cells can precisely represent tumor heterogeneity and provide useful information for cancer treatment and research. After spiking TGW neuroblastoma cells into blood derived from healthy volunteer, the cells were isolated by fluorescence-activated cell sorting....

Showing 1153 to 1164 of 1175 entries